Summary of available data:

As you can imagine, some types of data are not available for all organisms in TDR Targets (genome-wide knockouts is a good example). The reasons for this may vary: sometimes this is because the experimental data is lacking for a particular organism, sometimes it's because we need to process and check the data before loading; and yet sometimes it's because gathering and/or production of data is slow, as is the case for the manual curation of target validation credentials. In the table below we have tried to summarize the current status of data availability for each organism in TDR Targets.

If your queries are returning zero genes, you are probably searching on an attribute for which we have no data. Please check the table below for more details.

● genome-wide data available
● data available for a subset of the genome

Parent Group Organism Genes Essential
genes		 Curated
targets		 PDB
Structures		 Modbase
models		 Pfam
domains		 EC
numbers		 GO
terms		 Druggability Pathways Assayability Antigenicity
Bacteria Mycobacterium tuberculosis 4049 ● ● ● ● ● ● ● ● ● ● ●
Protist - Apicomplexa Plasmodium falciparum 5590   ● ● ● ● ● ● ● ● ● ●
Protist - Kinetoplastida Leishmania major 9222   ● ● ● ● ● ● ● ● ● ●
Protist - Kinetoplastida Trypanosoma brucei 10965 ● ● ● ● ● ● ● ● ● ● ●
Protist - Kinetoplastida Trypanosoma cruzi 25013     ● ● ● ● ● ● ● ● ●
Bacteria Wolbachia endosymbiont of Brugia malayi 805     ● ● ● ● ●   ●   ●
Bacteria Mycobacterium leprae 1608   ● ● ● ● ● ●   ● ● ●
Helminth - Nematoda Brugia malayi 11508       ● ● ● ●   ● ● ●
Protist - Apicomplexa Toxoplasma gondii 8032     ● ● ● ● ● ● ● ● ●
Protist - Apicomplexa Plasmodium vivax 5446     ● ● ● ● ● ● ● ● ●
Helminth - Trematoda Schistosoma mansoni 13263       ● ●   ●     ● ●
Helminth - Nematoda Onchocerca volvulus Coming soon.