Identification and ranking of targets against neglected tropical diseases
Posted by Dany Shanmugam on 2007-06-06 17:36:45
Ranked list of Mtb genes, by weighting, containg potential targets.
Click on the links below to browse the contents of each query or view the parameters used to filter genes. You can also use the checkboxes to select queries you would like to import into your history.
Mtb targets - ranked list from union of queries 1,3,4&5 (3093 records). Show parameters.
Score for genes in query #1 (Mtb genes with str or str model): 10 Score for genes in query #3 (Mtb gene in TDR target species + E.coli & yeast but not in mammals, C. elegans and fly): 15 Score for genes in query #4 (Mtb genes with any curation): 20 Score for genes in query #5 (Mtb genes essential in any of Cel, eco, sce and mtb): 25
Mtb genes with str or str model (2781 records). Show parameters.
species: mtu structures: PDB or Modbase
Mtb gene in TDR target species + E.coli & yeast but not in mammals, C. elegans and fly (804 records). Show parameters.
phylogenetic_distribution: NOT IN mmu, IN tcr, IN sce, IN pfa, NOT IN dme, NOT IN hsa, NOT IN cel, IN eco, IN lma, IN tbr species: mtu
Mtb genes with any curation (33 records). Show parameters.
curated: yes species: mtu
Mtb genes essential in any of Cel, eco, sce and mtb (1054 records). Show parameters.
essential: Any species: mtu
