TDR Targets

Brugia malayi genome prioritization including C. elegans tissue-specific gene expression data

Posted by Santiago Carmona on 2011-06-16 17:05:34

This ranked list of B. malayi targets was constructed from the published list 361 (for PLOS-NTD paper, http://tdrtargets.org/published/browse/361 ) by including additional criteria based on C. elegans tissue specific gene expression data.
C. elegans Neuron and Muscle specifically expressed genes (predicted) data was taken from "Global Prediction of Tissue-Specific Gene Expression and Context-Dependent Gene Networks in Caenorhabditis elegans", Chikina et. al.
Both gene sets were mapped to B. malayi genome. More information available in http://tdrtargets.org/published/browse/392
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Queries in this set

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B. malayi orthologs of C. elegans genes differentially expressed in muscle (519 records). Show parameters.

B. malayi orthologs of C. elegans genes differentially expressed in neurons (430 records). Show parameters.

Bma druggable precedence by similarity to starlite targets (806 records). Show parameters.

Bma - sterile in Cel (1461 records). Show parameters.