Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
1576 records found | Showing page 1 of 64 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
| M. tuberculosis | Rv0009 | OG5_128211 | Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ... |
| M. tuberculosis | Rv0012 | OG5_171691 | Probable conserved membrane protein |
| M. tuberculosis | Rv0013 | OG5_128663 | Possible anthranilate synthase component II TrpG (glutamine amidotransferase) |
| M. tuberculosis | Rv0014c | OG5_146588 | Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) |
| M. tuberculosis | Rv0015c | OG5_155711 | Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) |
| M. tuberculosis | Rv0016c | OG5_133524 | Probable penicillin-binding protein PbpA |
| M. tuberculosis | Rv0017c | OG5_179437 | Probable cell division protein RodA |
| M. tuberculosis | Rv0032 | OG5_126783 | Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv0033 | No group | Probable acyl carrier protein AcpA (ACP) |
| M. tuberculosis | Rv0035 | No group | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0036c | OG5_239103 | Conserved protein |
| M. tuberculosis | Rv0040c | OG5_237533 | Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen) |
| M. tuberculosis | Rv0042c | OG5_130983 | Possible transcriptional regulatory protein (probably MarR-family) |
| M. tuberculosis | Rv0043c | OG5_178458 | Probable transcriptional regulatory protein (probably GntR-family) |
| M. tuberculosis | Rv0044c | OG5_146706 | Possible oxidoreductase |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv0047c | OG5_178684 | Conserved protein |
| M. tuberculosis | Rv0053 | OG5_131749 | 30S ribosomal protein S6 RpsF |
| M. tuberculosis | Rv0056 | OG5_130699 | 50S ribosomal protein L9 RplI |
| M. tuberculosis | Rv0058 | OG5_131890 | Probable replicative DNA helicase DnaB |
| M. tuberculosis | Rv0060 | OG5_133608 | Conserved hypothetical protein |
| M. tuberculosis | Rv0062 | OG5_137267 | Possible cellulase CelA1 (endoglucanase) (endo-1,4-beta-glucanase) (FI-cmcase) ( ... |
| M. tuberculosis | Rv0066c | OG5_126691 | Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv0068 | OG5_126621 | Probable oxidoreductase |