Detailed information for compound 1034626

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 604.602 | Formula: C29H36N2O12
  • H donors: 5 H acceptors: 8 LogP: 3.79 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)c1c(OCCCCNC(=O)[C@@H](Cc2ccc(c(c2)C(=O)O)OCC(=O)O)NC(=O)OC(C)(C)C)cccc1O
  • InChi: 1S/C29H36N2O12/c1-29(2,3)43-28(39)31-19(15-17-10-11-21(42-16-23(33)34)18(14-17)26(36)37)25(35)30-12-5-6-13-41-22-9-7-8-20(32)24(22)27(38)40-4/h7-11,14,19,32H,5-6,12-13,15-16H2,1-4H3,(H,30,35)(H,31,39)(H,33,34)(H,36,37)/t19-/m1/s1
  • InChiKey: DRQXKGKHOSMCBP-LJQANCHMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protein tyrosine phosphatase, non-receptor type 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Protein-tyrosine phosphatase containing protein Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 Get druggable targets OG5_133865 All targets in OG5_133865
Loa Loa (eye worm) protein-tyrosine phosphatase Get druggable targets OG5_133865 All targets in OG5_133865
Echinococcus multilocularis tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Echinococcus granulosus tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma japonicum expressed protein Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma japonicum ko:K05696 protein tyrosine phosphatase, non-receptor type 1, putative Get druggable targets OG5_133865 All targets in OG5_133865
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0458 0.8158 1
Echinococcus granulosus cpg binding protein 0.0033 0.0463 0.0544
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0011 0.0068 0.0058
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0842 0.1007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0559 0.0659
Mycobacterium ulcerans integral membrane transport protein 0.001 0.0047 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.4213 0.4213
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0038 0.0559 0.0659
Onchocerca volvulus 0.0038 0.0559 0.0631
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0458 0.8158 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0091 0.1524 0.1845
Brugia malayi cathepsin L precursor 0.0091 0.1524 0.1845
Brugia malayi fibroinase precursor 0.0091 0.1524 0.1845
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0091 0.1524 0.1504
Schistosoma mansoni ap endonuclease 0.0008 0.0023 0.0002
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0173 0.3011 0.3672
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0014 0.0123 0.0125
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0011 0.0068 0.0058
Toxoplasma gondii sugar transporter ST3 0.001 0.0047 0.0025
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Brugia malayi hypothetical protein 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.1524 0.1524
Plasmodium falciparum serine repeat antigen 8 0.0091 0.1524 0.1504
Toxoplasma gondii transporter, major facilitator family protein 0.001 0.0047 0.0025
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0559 1 1
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0091 0.1524 0.5023
Onchocerca volvulus 0.0011 0.0068 0.0025
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.001 0.0047 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Echinococcus granulosus Sugar transporter ERD6 protein 0.001 0.0047 0.0033
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0091 0.1524 0.1504
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) fibroinase 0.0458 0.8158 1
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) sugar transporter 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0149 0.2563 0.3123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.5469 0.5469
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.4213 0.4213
Plasmodium falciparum serine repeat antigen 7 0.0091 0.1524 0.1504
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0012 0.0088 0.008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.6331 0.7755
Plasmodium falciparum cysteine proteinase falcipain 1 0.024 0.4213 0.42
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Schistosoma mansoni lamin 0.0012 0.0088 0.0082
Echinococcus granulosus cathepsin L cysteine proteinase 0.0458 0.8158 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0014 0.0123 0.0125
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0091 0.1524 0.1504
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.4213 0.5151
Schistosoma mansoni glucose transporter 0.001 0.0047 0.0033
Toxoplasma gondii sugar transporter ST1 0.001 0.0047 0.0025
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0038 0.0559 0.0538
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus granulosus cathepsin L 0.024 0.4213 0.5152
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0091 0.1524 0.1504
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0011 0.0068 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trypanosoma brucei pteridine reductase 1 0.0038 0.0559 0.0659
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Schistosoma mansoni cpg binding protein 0.0033 0.0463 0.0544
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0621 0.0735
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0038 0.0559 0.0662
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0357 0.6331 0.7754
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0785 0.0936
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0091 0.1524 0.1847
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Onchocerca volvulus 0.0011 0.0068 0.0025
Onchocerca volvulus 0.0011 0.0068 0.0025
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0559 1 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus multilocularis lamin dm0 0.0012 0.0088 0.0082
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0149 0.2563 0.3123
Loa Loa (eye worm) retinol dehydrogenase 12 0.0038 0.0559 0.0659
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Leishmania major hypothetical protein, conserved 0.001 0.0047 0.003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.239 0.2909
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0038 0.0559 0.0538
Trichomonas vaginalis set domain proteins, putative 0.0105 0.1766 0.1766
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0458 0.8158 0.8154
Loa Loa (eye worm) hypothetical protein 0.0149 0.2563 0.3123
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.239 0.2909
Trypanosoma cruzi major cysteine proteinase, putative 0.0091 0.1524 0.1845
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.519 0.6352
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.001 0.0047 0.0025
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0091 0.1524 0.1845
Brugia malayi Sugar transporter family protein 0.001 0.0047 0.003
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0091 0.1524 0.1504
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Giardia lamblia Cathepsin B precursor 0.0173 0.3011 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0038 0.0559 0.0659
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0038 0.0559 0.0659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0014 0.0123 0.0125
Loa Loa (eye worm) protein tyrosine phosphatase 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Onchocerca volvulus 0.0011 0.0068 0.0025
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Brugia malayi Cathepsin L-like precursor 0.0309 0.5469 0.6694
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0092 0.1538 0.1862
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Toxoplasma gondii hypothetical protein 0.0047 0.0731 0.071
Trypanosoma cruzi cruzipain precursor, putative 0.0149 0.2563 0.3123
Loa Loa (eye worm) sugar transporter 0.001 0.0047 0.003
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.519 0.6352
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0038 0.0559 0.0659
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0309 0.5469 0.6694
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Onchocerca volvulus 0.0011 0.0068 0.0025
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0091 0.1524 0.1504
Echinococcus multilocularis musashi 0.0012 0.0088 0.0082
Schistosoma mansoni hypothetical protein 0.001 0.0047 0.0033
Schistosoma mansoni lamin 0.0012 0.0088 0.0082
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0842 0.1007
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Plasmodium falciparum serine repeat antigen 4 0.0091 0.1524 0.1504
Brugia malayi major facilitator superfamily protein 0.001 0.0047 0.003
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0008 0.0023 0.0002
Leishmania major glucose transporter/membrane transporter D2, putative 0.001 0.0047 0.003
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Entamoeba histolytica cysteine proteinase 1, putative 0.024 0.4213 0.5151
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0423 0.7536 0.9235
Onchocerca volvulus 0.0458 0.8158 1
Mycobacterium ulcerans hypothetical protein 0.0155 0.2674 0.2657
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Onchocerca volvulus 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Echinococcus multilocularis cathepsin L cysteine protease 0.0458 0.8158 1
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0011 0.0068 0.0058
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Trypanosoma brucei glucose transporter 2A 0.001 0.0047 0.003
Schistosoma mansoni protein tyrosine phosphatase 0.0011 0.0068 0.0058
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) oxidoreductase 0.0038 0.0559 0.0659
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.094 0.0919
Onchocerca volvulus 0.0309 0.5469 0.6684
Trypanosoma brucei glucose transporter 1E 0.001 0.0047 0.003
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0423 0.7536 0.9235
Brugia malayi CXXC zinc finger family protein 0.0031 0.0432 0.0503
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0011 0.0068 0.0058
Leishmania major glucose transporter, lmgt3 0.001 0.0047 0.003
Plasmodium vivax serine-repeat antigen (SERA) 0.0091 0.1524 0.1504
Loa Loa (eye worm) cysteine protease 0.0458 0.8158 1
Plasmodium falciparum serine repeat antigen 6 0.0091 0.1524 0.1504
Schistosoma mansoni glucose transport protein 0.001 0.0047 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0013 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.0309 0.5469 0.6694
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni pcd6 interacting protein-related 0.0011 0.0068 0.0058
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.1524 0.1524
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Echinococcus multilocularis lamin 0.0012 0.0088 0.0082
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0458 0.8158 1
Toxoplasma gondii facilitative glucose transporter GT1 0.001 0.0047 0.0025
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi cathepsin L-like cysteine proteinase 0.0091 0.1524 0.1845
Onchocerca volvulus 0.0458 0.8158 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0014 0.0123 0.0125
Brugia malayi Sugar transporter family protein 0.001 0.0047 0.003
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0559 1 1
Trichomonas vaginalis ap endonuclease, putative 0.0008 0.0023 0.0023
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Plasmodium falciparum serine repeat antigen 9 0.0091 0.1524 0.1504
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0357 0.6331 0.7755
Trypanosoma brucei oxidoreductase-like protein 0.0038 0.0559 0.0659
Toxoplasma gondii cathepsin CPC1 0.0091 0.1524 0.1504
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Brugia malayi hypothetical protein 0.001 0.0047 0.003
Echinococcus multilocularis cathepsin L 0.024 0.4213 0.5152
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Echinococcus multilocularis Sugar transporter ERD6 protein 0.001 0.0047 0.0033
Brugia malayi cathepsin B-like cysteine proteinase 0.0357 0.6331 0.7754
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Leishmania major pteridine reductase 1 0.0038 0.0559 0.0659
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.6331 0.7755
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Brugia malayi Latrophilin receptor protein 2 0.0017 0.018 0.0193
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0038 0.0559 0.0659
Brugia malayi Protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.024 0.4213 0.5152
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0011 0.0068 0.0058
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) intermediate filament protein 0.0012 0.0088 0.008
Entamoeba histolytica hypothetical protein 0.0091 0.1524 0.1845
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Schistosoma mansoni intermediate filament proteins 0.0012 0.0088 0.0082
Onchocerca volvulus 0.0091 0.1524 0.182
Entamoeba histolytica cysteine protease, putative 0.0458 0.8158 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0091 0.1524 0.1504
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0173 0.3011 0.3672
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Echinococcus granulosus cysteine protease 0.024 0.4213 0.5152
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi Sugar transporter family protein 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.1524 0.1524
Schistosoma mansoni cpg binding protein 0.0033 0.0463 0.0544
Schistosoma mansoni cpg binding protein 0.0031 0.0432 0.0505
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Mycobacterium ulcerans oxidoreductase 0.0038 0.0559 0.0538
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi Cathepsin L-like precursor 0.0149 0.2563 0.3123
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0621 0.0735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Onchocerca volvulus 0.0011 0.0068 0.0025
Plasmodium vivax vivapain-1 0.024 0.4213 0.42
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Giardia lamblia Hypothetical protein 0.0091 0.1524 0.5023
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Echinococcus multilocularis cathepsin L 0.0091 0.1524 0.1847
Leishmania major myo-inositol/proton symporter (MIT) 0.001 0.0047 0.003
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0011 0.0068 0.0058
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0014 0.0123 0.0125
Echinococcus multilocularis synaptic vesicle 2 protein 0.001 0.0051 0.0037
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0037 0.0536 0.0633
Trypanosoma brucei cysteine peptidase C (CPC) 0.0173 0.3011 0.3672
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0091 0.1524 0.5023
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.024 0.4213 0.5151
Onchocerca volvulus Cathepsin F homolog 0.0458 0.8158 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0091 0.1524 0.1847
Trichomonas vaginalis glucose transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Brugia malayi Cathepsin L-like precursor 0.0309 0.5469 0.6694
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus synaptic vesicle 2 protein 0.001 0.0051 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus granulosus GPCR family 2 0.0017 0.018 0.0196
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.1066 0.1284
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Onchocerca volvulus Cathepsin L homolog 0.0458 0.8158 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0091 0.1524 0.1524
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.4213 0.5151
Entamoeba histolytica cysteine proteinase, putative 0.0309 0.5469 0.6694
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.018 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Brugia malayi cathepsin Z-like cysteine proteinase 0.0091 0.1524 0.1845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Plasmodium falciparum serine repeat antigen 1 0.0091 0.1524 0.1504
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0091 0.1524 0.5023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0008 0.0023 0.0002
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis myo-inositol transporter, putative 0.001 0.0047 0.0047
Trypanosoma brucei sugar transporter, putative 0.001 0.0047 0.003
Onchocerca volvulus 0.0011 0.0068 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0091 0.1524 0.1504
Entamoeba histolytica cysteine proteinase, putative 0.0458 0.8158 1
Brugia malayi major facilitator superfamily protein 0.001 0.0047 0.003
Loa Loa (eye worm) ctsf protein 0.0458 0.8158 1
Echinococcus granulosus cathepsin L cysteine protease 0.024 0.4213 0.5152
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Onchocerca volvulus 0.0011 0.0068 0.0025
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Schistosoma mansoni ap endonuclease 0.0008 0.0023 0.0002
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.1524 0.1524
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0536 0.0631
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0091 0.1524 0.1504
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0458 0.8158 1
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0559 1 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0423 0.7536 0.9235
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Plasmodium vivax serine-repeat antigen (SERA) 0.0091 0.1524 0.1504
Trypanosoma cruzi hexose transporter 0.001 0.0047 0.003
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Toxoplasma gondii sugar transporter ST2 0.001 0.0047 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0055 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Treponema pallidum exodeoxyribonuclease (exoA) 0.0008 0.0023 0.5
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.001 0.0047 0.0025
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0011 0.0068 0.0058
Brugia malayi cathepsin Z-like cysteine proteinase 0.0091 0.1524 0.1845
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Trichomonas vaginalis pten, drome, putative 0.0011 0.0068 0.0068
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.001 0.0051 0.0028
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.001 0.0047 0.0033
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Giardia lamblia Sugar-proton symporter 0.001 0.0047 0.0082
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Plasmodium falciparum serine repeat antigen 5 0.0091 0.1524 0.1504
Brugia malayi cathepsin L-like precursor 0.0309 0.5469 0.6694
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.519 0.6352
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Echinococcus granulosus cathepsin L 0.0091 0.1524 0.1847
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.001 0.0047 0.0025
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0091 0.1524 0.5023
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0038 0.0559 0.0659
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0075
Echinococcus granulosus lamin dm0 0.0012 0.0088 0.0082
Plasmodium falciparum enoyl-acyl carrier reductase 0.0559 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.024 0.4213 0.5151
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.018 0.0196
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0091 0.1524 0.1845
Onchocerca volvulus 4.1 G protein, putative homolog 0.0011 0.0068 0.0025
Brugia malayi cathepsin F-like cysteine proteinase 0.0091 0.1524 0.1845
Echinococcus multilocularis cathepsin L cysteine protease 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0038 0.0559 0.0538
Echinococcus multilocularis GPCR, family 2 0.0017 0.018 0.0196
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.018 0.0193
Echinococcus multilocularis cathepsin b 0.0357 0.6331 0.7755
Loa Loa (eye worm) hypothetical protein 0.0149 0.2563 0.3123
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Onchocerca volvulus 0.0031 0.0432 0.0474
Echinococcus granulosus protein tyrosine phosphatase n9 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Onchocerca volvulus Cathepsin L homolog 0.0091 0.1524 0.182
Giardia lamblia Cathepsin B precursor 0.0173 0.3011 1
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.6331 0.7755
Onchocerca volvulus 0.0014 0.0123 0.0093
Schistosoma mansoni cathepsin B (C01 family) 0.0091 0.1524 0.1847
Toxoplasma gondii cathepsin CPL 0.0458 0.8158 0.8154
Plasmodium vivax unspecified product 0.0091 0.1524 0.1504
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0621 0.0735
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0011 0.0068 0.0058
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0011 0.0068 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0173 0.3011 0.3011
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0011 0.0068 0.0058
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0309 0.5469 0.6694
Echinococcus multilocularis cysteine protease 0.0458 0.8158 1
Giardia lamblia Encystation-specific protease 0.0091 0.1524 0.5023
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0038 0.0559 0.0538
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi Papain family cysteine protease containing protein 0.024 0.4213 0.5151
Onchocerca volvulus 0.0011 0.0068 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.024 0.4213 0.5151
Echinococcus multilocularis cathepsin b 0.0357 0.6331 0.7755
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trypanosoma brucei protein tyrosine phosphatase 1 0.0011 0.0068 0.0055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.018 0.0193
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Leishmania major glucose transporter, lmgt2 0.001 0.0047 0.003
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Onchocerca volvulus 0.0458 0.8158 1
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0047 0.003
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0091 0.1524 0.1845
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0423 0.7536 0.9235
Plasmodium vivax hexose transporter 0.001 0.0047 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.0458 0.8158 1
Onchocerca volvulus 0.0011 0.0068 0.0025
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0011 0.0068 0.0058
Giardia lamblia Cathepsin L-like protease 0.0091 0.1524 0.5023
Trichomonas vaginalis ap endonuclease, putative 0.0008 0.0023 0.0023
Echinococcus granulosus cathepsin b 0.0357 0.6331 0.7755
Onchocerca volvulus 0.0458 0.8158 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0458 0.8158 1
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Mycobacterium tuberculosis Probable oxidoreductase 0.0038 0.0559 0.0538
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0458 0.8158 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0014 0.0123 0.0125
Trichomonas vaginalis glucose transporter, putative 0.001 0.0047 0.0047
Echinococcus granulosus cathepsin b 0.0357 0.6331 0.7755
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0091 0.1524 0.1504
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0309 0.5469 0.6694
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Mycobacterium tuberculosis Possible oxidoreductase 0.0038 0.0559 0.0538
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0054 0.0842 0.1007
Plasmodium vivax vivapain-3 0.024 0.4213 0.42
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Schistosoma mansoni cathepsin F (C01 family) 0.0458 0.8158 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Loa Loa (eye worm) histone methyltransferase 0.001 0.0055 0.0039
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.001 0.0047 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Onchocerca volvulus 0.0012 0.0088 0.005
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0055 0.0042
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi Protein-tyrosine phosphatase 1 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Plasmodium falciparum hexose transporter 0.001 0.0047 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Entamoeba histolytica cysteine proteinase 2 0.024 0.4213 0.5151
Brugia malayi Protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Echinococcus granulosus cathepsin l1 0.0309 0.5469 0.6695
Giardia lamblia Protein tyrosine phosphatase 0.0011 0.0068 0.0151
Trypanosoma cruzi cruzipain precursor, putative 0.0458 0.8158 1
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis cysteine protease 0.0458 0.8158 1
Leishmania major tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.239 0.2909
Onchocerca volvulus 0.0012 0.0088 0.005
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0038 0.0559 0.0659
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0149 0.2563 0.3123
Trypanosoma cruzi cysteine protease, putative 0.024 0.4213 0.5151
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0035
Schistosoma mansoni dihydropteridine reductase 0.0038 0.0559 0.0662
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Plasmodium vivax unspecified product 0.024 0.4213 0.42
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni cathepsin s 0.0149 0.2563 0.3124
Plasmodium falciparum cysteine proteinase falcipain 3 0.0458 0.8158 0.8154
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Schistosoma mansoni glucose transport protein 0.001 0.0047 0.0033
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0038 0.0559 0.0538
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0047 0.003
Trypanosoma cruzi cysteine proteinase, putative 0.024 0.4213 0.5151
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0091 0.1524 0.1504
Giardia lamblia Cathepsin B precursor 0.0173 0.3011 1
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni protein tyrosine phosphatase 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Plasmodium vivax SET domain protein, putative 0.0014 0.0123 0.01
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.2674 0.2657
Plasmodium vivax vivapain-2 0.0458 0.8158 0.8154
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0091 0.1524 0.1847
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Toxoplasma gondii cathepsin CPC2 0.0091 0.1524 0.1504
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0038 0.0559 0.0538
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Entamoeba histolytica cysteine proteinase, putative 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0842 0.1007
Trichomonas vaginalis hypothetical protein 0.0559 1 1
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0091 0.1524 0.1524
Plasmodium vivax unspecified product 0.0149 0.2563 0.2546
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Schistosoma mansoni cathepsin S (C01 family) 0.0091 0.1524 0.1847
Giardia lamblia Hexose transporter 0.001 0.0047 0.0082
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.018 0.0196
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Leishmania major glucose transporter, lmgt1 0.001 0.0047 0.003
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Onchocerca volvulus 0.0011 0.0068 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0536 0.0631
Leishmania major cysteine peptidase A (CPA) 0.0458 0.8158 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.519 0.6352
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0038 0.0559 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0458 0.8158 0.8158
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.024 0.4213 0.5152
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0047 0.003
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0423 0.7536 0.9235
Echinococcus multilocularis hypothetical protein 0.0011 0.0068 0.0058
Trypanosoma cruzi sugar transporter, putative 0.001 0.0047 0.003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.018 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.001 0.0047 0.0033
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus lamin 0.0012 0.0088 0.0082
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis cpg binding protein 0.0033 0.0463 0.0544
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0038 0.0559 0.0662
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0458 0.8158 1
Trichomonas vaginalis glucose transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0014 0.0123 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Loa Loa (eye worm) cathepsin B 0.0173 0.3011 0.3672
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0038 0.0559 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Schistosoma mansoni cathepsin F (C01 family) 0.0309 0.5469 0.6695
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0011 0.0068 0.0055
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0458 0.8158 0.8154
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0357 0.6331 0.7754
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0091 0.1524 0.1847
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0432 0.0503
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0053 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0012 0.0088 0.008
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0038 0.0559 0.0662
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0309 0.5469 0.6694
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.024 0.4213 0.5152
Plasmodium vivax sugar transporter, putative 0.001 0.0047 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Schistosoma mansoni cathepsin F (C01 family) 0.0458 0.8158 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0011 0.0068 0.0055
Plasmodium vivax vivapain-2 0.0458 0.8158 0.8154
Loa Loa (eye worm) hypothetical protein 0.0017 0.018 0.0193
Plasmodium falciparum serine repeat antigen 3 0.0091 0.1524 0.1504
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.024 0.4213 0.5151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.5469 0.5469
Schistosoma mansoni cathepsin C 0.0091 0.1524 0.1847
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0038 0.0559 0.0538
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0091 0.1524 0.1504
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Plasmodium falciparum serine repeat antigen 2 0.0091 0.1524 0.1504
Brugia malayi Pre-SET motif family protein 0.0014 0.0123 0.0123
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Giardia lamblia Cathepsin L-like protease 0.0091 0.1524 0.5023
Trypanosoma cruzi glucose transporter, putative 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus cathepsin l1 0.0458 0.8158 1
Brugia malayi hypothetical protein 0.001 0.0047 0.003
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0559 1 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Schistosoma mansoni glucose transport protein 0.001 0.0047 0.0033
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0038 0.0559 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.1524 0.1524
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0621 0.0735
Mycobacterium ulcerans sugar transporter 0.001 0.0047 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Brugia malayi intermediate filament protein 0.0012 0.0088 0.008
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0173 0.3011 0.3674
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Onchocerca volvulus 0.0011 0.0068 0.0025
Brugia malayi cathepsin F-like cysteine proteinase 0.0149 0.2563 0.3123
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0011 0.0068 0.0058
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0091 0.1524 0.1524
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Toxoplasma gondii cathepsin B 0.0173 0.3011 0.2995
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0011 0.0068 0.0058
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0047 0.003
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Giardia lamblia Hypothetical protein 0.0091 0.1524 0.5023
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Onchocerca volvulus 0.0105 0.1766 0.2119
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0014 0.0123 0.01
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0038 0.0559 0.0538
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transport protein, putative 0.001 0.0047 0.0047
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0091 0.1524 0.1504
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Onchocerca volvulus 0.0038 0.0559 0.0631
Echinococcus multilocularis 0.0011 0.0068 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0014 0.0123 0.0125
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni protein tyrosine phosphatase 0.0011 0.0068 0.0058
Echinococcus granulosus intermediate filament protein 0.0012 0.0088 0.0082
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Leishmania major oxidoreductase-like protein 0.0038 0.0559 0.0659
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0038 0.0559 0.0659
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0038 0.0559 0.0659
Trypanosoma cruzi major cysteine proteinase, putative 0.0091 0.1524 0.1845
Brugia malayi Pre-SET motif family protein 0.0092 0.1538 0.1862
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Mycobacterium tuberculosis Possible oxidoreductase 0.0038 0.0559 0.0538
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0559 1 1
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0038 0.0559 0.0538
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0149 0.2563 0.3123
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0091 0.1524 0.1504
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0011 0.0068 0.0055
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 5.7 Inhibition of PTP1B ChEMBL. 19385614

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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