Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Latrophilin receptor protein 2 | 0.0035 | 0.0195 | 0.0251 |
Leishmania major | cytochrome p450-like protein | 0.004 | 0.0254 | 0.0954 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0158 | 0.0204 |
Echinococcus granulosus | GPCR family 2 | 0.0035 | 0.0195 | 0.0215 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0027 | 0.0114 | 0.0125 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.1384 | 0.525 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0035 | 0.0195 | 0.0251 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0109 | 0.1025 | 0.1323 |
Chlamydia trachomatis | SWIB complex protein | 0.0713 | 0.7748 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0037 | 0.0223 | 0.0836 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0114 | 0.1083 | 0.8837 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0385 | 0.043 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.006 | 0.0483 | 0.048 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0254 | 0.2634 | 0.3325 |
Echinococcus multilocularis | cathepsin L | 0.0019 | 0.0023 | 0.0019 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0057 | 0.0204 |
Onchocerca volvulus | 0.0051 | 0.0381 | 0.0384 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.0483 | 0.054 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0223 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0087 | 0.0112 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0223 | 0.0284 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0025 | 0.0087 | 0.0112 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0254 | 0.2634 | 0.2631 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0027 | 0.0114 | 0.0148 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0057 | 0.0054 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0127 | 0.1225 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0713 | 0.7748 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0027 | 0.0114 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0381 | 0.0491 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0713 | 0.7748 | 1 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0254 | 0.2634 | 0.2964 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0037 | 0.0223 | 0.0288 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0254 | 0.2634 | 0.2964 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0713 | 0.7748 | 0.7747 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0114 | 0.1083 | 0.8837 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0254 | 0.2634 | 0.2964 |
Echinococcus granulosus | cysteine protease | 0.0019 | 0.0023 | 0.0022 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1025 | 0.1323 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0368 | 0.0471 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0019 | 0.0023 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 0.7748 | 0.8726 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0127 | 0.1225 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0713 | 0.7748 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0057 | 0.0204 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0025 | 0.0087 | 0.0107 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0483 | 0.0623 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0027 | 0.0114 | 0.0421 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0254 | 0.2634 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0165 | 0.0212 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.004 | 0.0254 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0114 | 0.1083 | 0.8837 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0483 | 0.0623 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.0057 | 0.2143 |
Brugia malayi | brahma associated protein 60 kDa | 0.0713 | 0.7748 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0037 | 0.0223 | 0.0248 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0129 | 0.1248 | 0.4731 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0385 | 0.043 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.1384 | 0.525 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0027 | 0.0114 | 0.0125 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 0.7748 | 0.8726 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0087 | 0.0112 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0027 | 0.0114 | 0.4558 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0548 | 0.5902 | 0.6646 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0027 | 0.0114 | 0.0143 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma cruzi | cysteine protease, putative | 0.0019 | 0.0023 | 0.0074 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Onchocerca volvulus | Cathepsin F homolog | 0.0037 | 0.0223 | 0.0178 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0025 | 0.0087 | 0.0107 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0223 | 0.022 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0023 | 0.0025 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0027 | 0.0114 | 0.0421 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.0057 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0254 | 0.2634 | 0.2964 |
Echinococcus multilocularis | lamin | 0.0032 | 0.0165 | 0.0161 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.006 | 0.0483 | 0.054 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.1384 | 0.525 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0254 | 0.2634 | 0.2631 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0114 | 0.1083 | 0.8837 |
Schistosoma mansoni | brg-1 associated factor | 0.0713 | 0.7748 | 0.8726 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0057 | 0.0061 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0057 | 0.0061 |
Plasmodium vivax | vivapain-3 | 0.0019 | 0.0023 | 0.0025 |
Onchocerca volvulus | Cathepsin L homolog | 0.0037 | 0.0223 | 0.0178 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0057 | 0.1711 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0019 | 0.0023 | 0.0022 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.006 | 0.0483 | 0.054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0019 | 0.0023 | 0.0022 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0057 | 0.0069 |
Schistosoma mansoni | RNA binding protein | 0.0254 | 0.2634 | 0.2964 |
Plasmodium vivax | hypothetical protein, conserved | 0.0713 | 0.7748 | 1 |
Onchocerca volvulus | 0.0032 | 0.0165 | 0.0102 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0019 | 0.0023 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0548 | 0.5902 | 0.6646 |
Brugia malayi | Cathepsin L-like precursor | 0.0025 | 0.0087 | 0.0112 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0385 | 0.0497 |
Entamoeba histolytica | cysteine protease, putative | 0.0037 | 0.0223 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0141 | 0.1384 | 0.525 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0385 | 0.0382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0223 | 0.022 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0087 | 0.0112 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0368 | 0.1386 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0027 | 0.0114 | 0.0148 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0027 | 0.0114 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0165 | 0.0181 |
Onchocerca volvulus | Cathepsin L homolog | 0.0037 | 0.0223 | 0.0178 |
Onchocerca volvulus | 0.0713 | 0.7748 | 1 | |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0019 | 0.0023 | 0.0074 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0223 | 0.022 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0127 | 0.1225 | 1 |
Brugia malayi | glutathione reductase | 0.005 | 0.0368 | 0.0475 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0641 | 0.0718 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0037 | 0.0223 | 0.0248 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0165 | 0.0212 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0368 | 0.0475 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0381 | 0.0425 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0027 | 0.0114 | 0.0148 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0815 | 0.8879 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | cathepsin l1 | 0.0025 | 0.0087 | 0.0094 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.7747 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0037 | 0.0223 | 0.0288 |
Brugia malayi | cathepsin L-like precursor | 0.0025 | 0.0087 | 0.0112 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0368 | 0.0475 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0057 | 0.0069 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0075 | 0.0641 | 0.0827 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Echinococcus multilocularis | GPCR, family 2 | 0.0035 | 0.0195 | 0.0191 |
Schistosoma mansoni | fusion | 0.0254 | 0.2634 | 0.2964 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0385 | 0.043 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0385 | 0.0497 |
Loa Loa (eye worm) | CYP4Cod1 | 0.004 | 0.0254 | 0.0328 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0025 | 0.0087 | 0.0094 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0109 | 0.1025 | 0.1323 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0223 | 0.0248 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0223 | 0.022 |
Schistosoma mansoni | lamin | 0.0032 | 0.0165 | 0.0181 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0114 | 0.1083 | 0.8837 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0641 | 0.0827 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0385 | 0.043 |
Schistosoma mansoni | zinc finger protein | 0.0254 | 0.2634 | 0.2964 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0037 | 0.0223 | 0.0288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0165 | 0.0161 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0019 | 0.0023 | 0.0022 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0254 | 0.2634 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0057 | 0.0061 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0111 | 0.1048 | 0.3969 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0254 | 0.2634 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0057 | 0.044 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0223 | 0.0248 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0195 | 0.0215 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0254 | 0.2634 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0254 | 0.2634 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0025 | 0.0087 | 0.3182 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0368 | 0.0471 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0057 | 0.0069 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0223 | 0.022 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0019 | 0.0023 | 0.0022 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0165 | 0.0212 |
Toxoplasma gondii | cathepsin CPL | 0.0037 | 0.0223 | 0.0284 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.1384 | 0.525 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0713 | 0.7748 | 0.8726 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0019 | 0.0023 | 0.0025 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0713 | 0.7748 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0057 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0195 | 0.0251 |
Echinococcus multilocularis | tumor protein p63 | 0.035 | 0.3708 | 0.3706 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0027 | 0.0114 | 0.0421 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0057 | 0.0069 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0019 | 0.0023 | 0.0074 |
Loa Loa (eye worm) | fibroinase | 0.0037 | 0.0223 | 0.0288 |
Loa Loa (eye worm) | brahma associated protein | 0.0713 | 0.7748 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0037 | 0.0223 | 0.0284 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0023 | 0.0025 |
Trypanosoma cruzi | cytochrome P450, putative | 0.004 | 0.0254 | 0.0954 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0165 | 0.0161 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0027 | 0.0114 | 0.0143 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.0483 | 0.054 |
Trypanosoma brucei | cytochrome P450, putative | 0.004 | 0.0254 | 0.0954 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0057 | 0.0069 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.1225 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.006 | 0.0483 | 0.054 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0195 | 0.0215 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0027 | 0.0114 | 0.0143 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0165 | 0.0181 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0027 | 0.0114 | 0.0143 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Echinococcus granulosus | cathepsin L | 0.0019 | 0.0023 | 0.0022 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0057 | 0.4852 |
Brugia malayi | Cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Plasmodium vivax | vivapain-1 | 0.0019 | 0.0023 | 0.0025 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0114 | 0.1083 | 0.8837 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0037 | 0.0223 | 0.0284 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0223 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.035 | 0.3708 | 0.4175 |
Trypanosoma cruzi | cytochrome P450, putative | 0.004 | 0.0254 | 0.0954 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0254 | 0.2634 | 0.2631 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0385 | 0.043 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0109 | 0.1025 | 0.1323 |
Brugia malayi | Cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.1384 | 0.525 |
Echinococcus granulosus | lamin | 0.0032 | 0.0165 | 0.0181 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.0368 | 0.1386 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0004 | 0.0005 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0037 | 0.0223 | 0.0288 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0195 | 0.0191 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Loa Loa (eye worm) | cysteine protease | 0.0037 | 0.0223 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 0.7748 | 0.8726 |
Trichomonas vaginalis | chaperonin, putative | 0.0027 | 0.0114 | 0.0143 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.006 | 0.0483 | 0.048 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0254 | 0.2634 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0165 | 0.0212 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0035 | 0.0195 | 0.0251 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0057 | 0.0074 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.8726 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0037 | 0.0223 | 0.0284 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Toxoplasma gondii | ran binding protein | 0.0254 | 0.2634 | 0.3396 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0165 | 0.0181 |
Echinococcus multilocularis | geminin | 0.0548 | 0.5902 | 0.5901 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Plasmodium vivax | unspecified product | 0.0019 | 0.0023 | 0.0025 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0057 | 0.0204 |
Onchocerca volvulus | 0.0032 | 0.0165 | 0.0102 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.1384 | 0.525 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0368 | 0.0471 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0027 | 0.0114 | 0.0125 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0223 | 0.022 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0254 | 0.2634 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0368 | 0.0471 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0195 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0368 | 0.0475 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Brugia malayi | brahma associated protein 60 kDa | 0.0713 | 0.7748 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0057 | 0.0204 |
Brugia malayi | Cathepsin L-like precursor | 0.0025 | 0.0087 | 0.0112 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0027 | 0.0114 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0165 | 0.0212 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0815 | 0.8879 | 0.8878 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0368 | 0.0365 |
Brugia malayi | YY1-associated factor 2 | 0.0254 | 0.2634 | 0.3399 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0127 | 0.0163 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0385 | 0.0382 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0223 | 0.0836 |
Schistosoma mansoni | lamin | 0.0032 | 0.0165 | 0.0181 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0023 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0019 | 0.0023 | 0.0074 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0368 | 0.2985 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0223 | 0.0288 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0254 | 0.2634 | 0.2964 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0368 | 0.0471 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0483 | 0.0623 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0254 | 0.2634 | 0.3396 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.7747 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0713 | 0.7748 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0254 | 0.2634 | 0.3396 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Echinococcus granulosus | geminin | 0.0548 | 0.5902 | 0.6646 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0019 | 0.0023 | 0.0074 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0037 | 0.0223 | 0.0248 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0368 | 0.0411 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0815 | 0.8879 | 1 |
Leishmania major | trypanothione reductase | 0.005 | 0.0368 | 0.1386 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0254 | 0.2634 | 0.2631 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.7747 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0023 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Schistosoma mansoni | hypothetical protein | 0.0254 | 0.2634 | 0.2964 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0057 | 0.0074 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 22 uM | Inhibition of farnesyl transferase | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.