Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0005 | 0.0016 | 0.0016 |
Echinococcus granulosus | E3 ubiquitin protein ligase RNF146 | 0.0005 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1486 | 0.1841 |
Onchocerca volvulus | 0.0023 | 0.0579 | 0.0699 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0093 | 0.2786 | 0.3452 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0008 | 0.0118 | 0.0118 |
Onchocerca volvulus | 0.0045 | 0.1289 | 0.158 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0329 | 0.0329 |
Brugia malayi | hypothetical protein | 0.022 | 0.6787 | 0.8407 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.2786 | 0.2786 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0008 | 0.0118 | 0.0118 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0093 | 0.2786 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1326 | 0.1643 |
Brugia malayi | Neuralized family protein | 0.0005 | 0.0016 | 0.002 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0008 | 0.0118 | 0.0146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.1197 | 0.1197 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0008 | 0.0118 | 0.0126 |
Chlamydia trachomatis | DNA topoisomerase I | 0.026 | 0.8072 | 0.5 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Brugia malayi | YY1-associated factor 2 | 0.0093 | 0.2786 | 0.3452 |
Echinococcus multilocularis | RING finger protein 185 | 0.0005 | 0.0016 | 0.0016 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0008 | 0.0118 | 0.0118 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0051 | 0.1486 | 0.1486 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Echinococcus multilocularis | E3 ubiquitin protein ligase LRSAM1 | 0.0005 | 0.0016 | 0.0016 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0093 | 0.2786 | 0.3452 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.026 | 0.8072 | 1 |
Echinococcus multilocularis | E3 ubiquitin protein ligase MYLIP | 0.0005 | 0.0016 | 0.0016 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0178 | 0.547 | 0.547 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0093 | 0.2786 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0093 | 0.2786 | 0.2786 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0061 | 0.1781 | 0.1781 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0006 | 0.0044 | 0.0044 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0093 | 0.2786 | 1 |
Chlamydia trachomatis | SWIB complex protein | 0.026 | 0.8072 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Echinococcus multilocularis | RING finger and transmembrane domain containing protein | 0.0005 | 0.0016 | 0.0016 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0008 | 0.0118 | 0.0118 |
Echinococcus multilocularis | E3 ubiquitin protein ligase mib1 | 0.0005 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | RiNg Finger protein family member | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | peter pan-related | 0.0005 | 0.0016 | 0.0016 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0008 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | brg-1 associated factor | 0.026 | 0.8072 | 0.8072 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2786 | 0.3452 |
Echinococcus multilocularis | cpg binding protein | 0.0024 | 0.062 | 0.062 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0008 | 0.0118 | 0.0118 |
Onchocerca volvulus | 0.0093 | 0.2786 | 0.3438 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0329 | 0.0329 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0093 | 0.2786 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0008 | 0.0118 | 0.0118 |
Entamoeba histolytica | hypothetical protein | 0.0005 | 0.0016 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0024 | 0.062 | 0.062 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | Hypothetical RING finger protein C16C10.7 in chromosome III | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | coup transcription factor | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.1197 | 0.1197 |
Brugia malayi | RING finger protein 20 | 0.0005 | 0.0016 | 0.002 |
Echinococcus multilocularis | geminin | 0.0117 | 0.356 | 0.356 |
Schistosoma mansoni | cpg binding protein | 0.0023 | 0.0579 | 0.0579 |
Schistosoma mansoni | hypothetical protein | 0.0322 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0008 | 0.0118 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.356 | 0.356 |
Schistosoma mansoni | thyroid hormone receptor | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0329 | 0.0329 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0329 | 0.0329 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0008 | 0.0118 | 0.0118 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0088 | 0.0088 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.022 | 0.6787 | 0.6787 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0008 | 0.0118 | 0.0118 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0093 | 0.2786 | 0.3452 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0093 | 0.2786 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2786 | 0.3452 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.026 | 0.8072 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.026 | 0.8072 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0008 | 0.0118 | 0.0146 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0093 | 0.2786 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2786 | 0.3452 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0045 | 0.1289 | 0.1289 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0329 | 0.0408 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0007 | 0.0085 | 0.0105 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0329 | 0.0329 |
Brugia malayi | Protein kinase domain containing protein | 0.0061 | 0.1781 | 0.2207 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.026 | 0.8072 | 0.8072 |
Schistosoma mansoni | RNA binding protein | 0.0093 | 0.2786 | 0.2786 |
Brugia malayi | CXXC zinc finger family protein | 0.0023 | 0.0579 | 0.0717 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus granulosus | FTZ F1 alpha | 0.031 | 0.9645 | 0.9645 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0274 | 0.851 | 0.851 |
Giardia lamblia | Kinase, TTK | 0.0061 | 0.1781 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Brugia malayi | nuclear receptor NHR-88 | 0.0008 | 0.0118 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2786 | 0.3452 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0322 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0005 | 0.0016 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0865 | 0.0865 |
Onchocerca volvulus | 0.0093 | 0.2786 | 0.3438 | |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0329 | 0.0329 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.026 | 0.8072 | 0.8072 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0008 | 0.0118 | 0.0118 |
Onchocerca volvulus | 0.0045 | 0.1279 | 0.1567 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0329 | 0.0329 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0032 | 0.0865 | 0.1071 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.1197 | 0.1197 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0093 | 0.2786 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0016 | 0.0016 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0008 | 0.0118 | 0.0118 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0045 | 0.1289 | 0.1289 |
Entamoeba histolytica | SPRY domain protein | 0.0005 | 0.0016 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0329 | 0.0329 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.1197 | 0.1197 |
Schistosoma mansoni | survival motor neuron protein | 0.0045 | 0.1279 | 0.1279 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0046 | 0.1326 | 0.1643 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Echinococcus granulosus | RING finger and transmembrane domain containing protein | 0.0005 | 0.0016 | 0.0016 |
Echinococcus multilocularis | E3 ubiquitin protein ligase Bre1 | 0.0005 | 0.0016 | 0.0016 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0008 | 0.0118 | 0.0118 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | zinc finger protein | 0.0093 | 0.2786 | 0.2786 |
Schistosoma mansoni | inhibitor of apoptosis 1 diap1 | 0.0005 | 0.0016 | 0.0016 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0093 | 0.2786 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0008 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Toxoplasma gondii | ran binding protein | 0.0093 | 0.2786 | 0.3438 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0045 | 0.1289 | 0.1597 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.356 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Schistosoma mansoni | mind bomb | 0.0005 | 0.0016 | 0.0016 |
Echinococcus multilocularis | ring finger protein 113a | 0.0005 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0008 | 0.0118 | 0.0146 |
Schistosoma mansoni | thyroid hormone receptor | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0008 | 0.0118 | 0.0118 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Onchocerca volvulus | 0.0008 | 0.0118 | 0.0126 | |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0008 | 0.0118 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0329 | 0.0329 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0093 | 0.2786 | 0.2786 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Giardia lamblia | Kinase | 0.0005 | 0.0028 | 0.0069 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0005 | 0.0028 | 0.0028 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0178 | 0.547 | 0.547 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.026 | 0.8072 | 0.8072 |
Brugia malayi | Zinc finger protein 183 homolog | 0.0005 | 0.0016 | 0.002 |
Brugia malayi | brahma associated protein 60 kDa | 0.026 | 0.8072 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0061 | 0.1781 | 0.2191 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | ring finger protein 170 | 0.0005 | 0.0016 | 0.0016 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.1197 | 0.1197 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Echinococcus granulosus | RING finger protein 185 | 0.0005 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0329 | 0.0408 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0006 | 0.0044 | 0.0044 |
Echinococcus granulosus | ring finger protein 113a | 0.0005 | 0.0016 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.026 | 0.8072 | 0.8072 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0008 | 0.0118 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0008 | 0.0118 | 0.0118 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Brugia malayi | RING zinc finger protein | 0.0005 | 0.0016 | 0.002 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0045 | 0.1279 | 0.1584 |
Schistosoma mansoni | peter pan-related | 0.0005 | 0.0016 | 0.0016 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0051 | 0.1486 | 0.1486 |
Onchocerca volvulus | 0.0093 | 0.2786 | 0.3438 | |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0329 | 0.0329 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.022 | 0.6787 | 0.6787 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0008 | 0.0118 | 0.0118 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0093 | 0.2786 | 0.2786 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.026 | 0.8072 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.026 | 0.8072 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0061 | 0.1781 | 0.2191 |
Trichomonas vaginalis | helicase, putative | 0.0005 | 0.0029 | 0.0016 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0093 | 0.2786 | 0.2786 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0008 | 0.0118 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0061 | 0.1781 | 0.2191 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0008 | 0.0118 | 0.0146 |
Giardia lamblia | Kinase, NEK | 0.0005 | 0.0028 | 0.0069 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0046 | 0.1326 | 0.1643 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.1279 | 0.1279 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0008 | 0.0118 | 0.0118 |
Echinococcus granulosus | geminin | 0.0117 | 0.356 | 0.356 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0093 | 0.2786 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0093 | 0.2786 | 1 |
Echinococcus granulosus | ring finger protein 170 | 0.0005 | 0.0016 | 0.0016 |
Echinococcus granulosus | E3 ubiquitin protein ligase LRSAM1 | 0.0005 | 0.0016 | 0.0016 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0045 | 0.1289 | 0.1289 |
Echinococcus granulosus | E3 ubiquitin protein ligase Bre1 | 0.0005 | 0.0016 | 0.0016 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0008 | 0.0118 | 0.0118 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0005 | 0.0016 | 0.002 |
Echinococcus granulosus | E3 ubiquitin protein ligase MYLIP | 0.0005 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.026 | 0.8072 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.6787 | 0.8407 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0061 | 0.1781 | 0.1781 |
Schistosoma mansoni | rnf5 | 0.0005 | 0.0016 | 0.0016 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.026 | 0.8072 | 1 |
Onchocerca volvulus | 0.0093 | 0.2786 | 0.3438 | |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0008 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | histone methyltransferase | 0.0007 | 0.0088 | 0.0109 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0051 | 0.1486 | 0.1486 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0008 | 0.0118 | 0.0126 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0006 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0865 | 0.1071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | hypothetical protein | 0.0005 | 0.0016 | 0.0016 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0329 | 0.0408 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0008 | 0.0118 | 0.0146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0008 | 0.0118 | 0.0118 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0042 | 0.1197 | 0.1482 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0093 | 0.2786 | 0.3438 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0045 | 0.1289 | 0.1289 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0023 | 0.0579 | 0.0717 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0051 | 0.1486 | 0.1841 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | ecdysteroid receptor | 0.0008 | 0.0118 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.026 | 0.8072 | 0.8072 |
Loa Loa (eye worm) | brahma associated protein | 0.026 | 0.8072 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0045 | 0.1289 | 0.1289 |
Brugia malayi | B-box zinc finger family protein | 0.0005 | 0.0016 | 0.002 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0093 | 0.2786 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Loa Loa (eye worm) | MBCTL1 | 0.0051 | 0.1486 | 0.1841 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0005 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus granulosus | E3 ubiquitin protein ligase mib1 | 0.0005 | 0.0016 | 0.0016 |
Echinococcus multilocularis | 0.0005 | 0.0016 | 0.0016 | |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0093 | 0.2786 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.1289 | 0.1597 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.1197 | 0.1197 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0046 | 0.1326 | 0.1643 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0008 | 0.0118 | 0.0118 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0008 | 0.0118 | 0.0118 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0088 | 0.0088 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0008 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0043 | 0.1216 | 0.1489 |
Schistosoma mansoni | nuclear hormone receptor | 0.0008 | 0.0118 | 0.0118 |
Echinococcus granulosus | cell growth regulator with ring finger domain | 0.0005 | 0.0016 | 0.0016 |
Echinococcus granulosus | cpg binding protein | 0.0024 | 0.062 | 0.062 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0093 | 0.2786 | 0.2786 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0093 | 0.2786 | 0.2786 |
Schistosoma mansoni | hypothetical protein | 0.026 | 0.8072 | 0.8072 |
Schistosoma mansoni | cpg binding protein | 0.0024 | 0.062 | 0.062 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.026 | 0.8072 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0029 | 0.0016 |
Brugia malayi | brahma associated protein 60 kDa | 0.026 | 0.8072 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0051 | 0.1486 | 0.1486 |
Loa Loa (eye worm) | RING finger protein 20 | 0.0005 | 0.0016 | 0.002 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Loa Loa (eye worm) | TTK protein kinase | 0.0061 | 0.1781 | 0.2207 |
Entamoeba histolytica | zinc finger domain containing protein | 0.0005 | 0.0016 | 0.5 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.026 | 0.8072 | 1 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0093 | 0.2786 | 0.3438 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0045 | 0.1289 | 0.1289 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.026 | 0.8072 | 0.8072 |
Schistosoma mansoni | fusion | 0.0093 | 0.2786 | 0.2786 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0048 | 0.1377 | 0.1377 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.026 | 0.8072 | 0.8072 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0329 | 0.0408 |
Brugia malayi | mbt repeat family protein | 0.0045 | 0.1289 | 0.1597 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0006 | 0.0044 | 0.0044 |
Brugia malayi | steroid hormone receptor | 0.0008 | 0.0118 | 0.0146 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0.2786 | 1 |
Schistosoma mansoni | ring finger protein 151 | 0.0005 | 0.0016 | 0.0016 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0093 | 0.2786 | 0.3452 |
Giardia lamblia | Kinase, NEK | 0.0005 | 0.0028 | 0.0069 |
Brugia malayi | mbt repeat family protein | 0.0045 | 0.1289 | 0.1597 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2786 | 0.3452 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0005 | 0.0029 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0008 | 0.0118 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.026 | 0.8072 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0042 | 0.1197 | 0.1482 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0051 | 0.1486 | 0.1486 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0006 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0008 | 0.0118 | 0.0146 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.026 | 0.8072 | 0.8072 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0016 | 0.002 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0045 | 0.1289 | 0.1289 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0045 | 0.1289 | 0.158 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0061 | 0.1781 | 0.1781 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0093 | 0.2786 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0118 | 0.0146 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -9 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.