Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Cathepsin F homolog | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.013 | 0.0215 | 0.0215 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0472 | 0.1098 | 0.1991 |
Brugia malayi | carbohydrate phosphorylase | 0.013 | 0.0215 | 0.0215 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Hypothetical protein | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0713 | 0.1719 | 0.1719 |
Brugia malayi | Cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.0259 | 0.0259 |
Echinococcus granulosus | cathepsin L | 0.1114 | 0.2755 | 0.2755 |
Schistosoma mansoni | cathepsin s | 0.0642 | 0.1536 | 0.1536 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0642 | 0.1536 | 0.1536 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.1862 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0916 | 0.2244 | 0.1288 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.1114 | 0.2755 | 0.2755 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.2475 | 0.6268 | 0.5808 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Plasmodium vivax | vivapain-2 | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.0097 | 1 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0022 | 0.0022 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.2031 | 0.5122 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0642 | 0.1536 | 0.0492 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Schistosoma mansoni | cathepsin C | 0.0472 | 0.1098 | 0.1098 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0017 | 0.0017 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1114 | 0.2755 | 0.2755 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0375 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0085 | 0.016 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0472 | 0.1098 | 0.1991 |
Echinococcus granulosus | cathepsin l1 | 0.1389 | 0.3464 | 0.3464 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.1862 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Brugia malayi | cathepsin L precursor | 0.0472 | 0.1098 | 0.1098 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0557 | 0.1316 | 0.2424 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Onchocerca volvulus | Cathepsin L homolog | 0.2031 | 0.5122 | 1 |
Toxoplasma gondii | cathepsin B | 0.1539 | 0.3851 | 0.7471 |
Onchocerca volvulus | 0.0472 | 0.1098 | 0.2143 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Leishmania major | cysteine peptidase A (CPA) | 0.2031 | 0.5122 | 0.5258 |
Plasmodium vivax | unspecified product | 0.1114 | 0.2755 | 0.529 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1389 | 0.3464 | 0.6749 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1114 | 0.2755 | 0.5377 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.013 | 0.0215 | 0.0215 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.2031 | 0.5122 | 1 |
Echinococcus multilocularis | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0695 | 0.1672 | 0.1672 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0472 | 0.1098 | 0.2139 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.0259 | 0.0259 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1539 | 0.3851 | 0.3093 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1389 | 0.3464 | 0.3464 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1539 | 0.3851 | 0.312 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.0097 |
Entamoeba histolytica | cysteine protease, putative | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0259 | 0.0259 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.0259 | 0.0259 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1114 | 0.2755 | 0.2755 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | cathepsin L | 0.0472 | 0.1098 | 0.1098 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0375 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0056 | 0.0024 | 0.0024 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0472 | 0.1098 | 0.1991 |
Echinococcus multilocularis | cathepsin L | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0266 | 0.0564 | 0.0564 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0017 | 0.0017 |
Brugia malayi | Papain family cysteine protease containing protein | 0.2031 | 0.5122 | 0.5122 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Echinococcus granulosus | geminin | 0.0184 | 0.0353 | 0.0353 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus multilocularis | geminin | 0.0184 | 0.0353 | 0.0353 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.0357 | 0.0357 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2031 | 0.5122 | 0.452 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Brugia malayi | Cathepsin L-like precursor | 0.0642 | 0.1536 | 0.1536 |
Loa Loa (eye worm) | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0048 | 0.0003 | 0.0006 |
Brugia malayi | Heterochromatin protein 1 | 0.008 | 0.0085 | 0.0085 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0415 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0642 | 0.1536 | 0.0492 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0472 | 0.1098 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Brugia malayi | fibroinase precursor | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0472 | 0.1098 | 0.2139 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Toxoplasma gondii | cathepsin CPC2 | 0.0557 | 0.1316 | 0.2424 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0085 | 0.0085 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0557 | 0.1316 | 0.2424 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Schistosoma mansoni | hypothetical protein | 0.0286 | 0.0617 | 0.0617 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.1114 | 0.2755 | 0.1862 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0695 | 0.1672 | 0.4007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1389 | 0.3464 | 0.6762 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0472 | 0.1098 | 0.1991 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0017 | 0.0017 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.013 | 0.0215 | 0.042 |
Onchocerca volvulus | Cathepsin L homolog | 0.2031 | 0.5122 | 1 |
Toxoplasma gondii | cathepsin CPC1 | 0.0695 | 0.1672 | 0.3134 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0056 | 0.0024 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Entamoeba histolytica | hypothetical protein | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1389 | 0.3464 | 0.6762 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.061 | 0.1454 | 0.2835 |
Entamoeba histolytica | cysteine proteinase 2 | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Plasmodium vivax | vivapain-1 | 0.1114 | 0.2755 | 0.529 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1833 | 0.4611 | 0.3946 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0713 | 0.1719 | 0.1719 |
Brugia malayi | follicle stimulating hormone receptor | 0.0266 | 0.0564 | 0.0564 |
Brugia malayi | Cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0642 | 0.1536 | 0.1536 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Plasmodium vivax | unspecified product | 0.0472 | 0.1098 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1539 | 0.3851 | 0.7517 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Loa Loa (eye worm) | hypothetical protein | 0.2031 | 0.5122 | 0.5122 |
Echinococcus granulosus | cysteine protease | 0.1114 | 0.2755 | 0.2755 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0017 | 0.0017 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.0357 | 0.0357 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0415 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.0259 | 0.0259 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Echinococcus multilocularis | cathepsin L | 0.1114 | 0.2755 | 0.2755 |
Chlamydia trachomatis | glycogen phosphorylase | 0.013 | 0.0215 | 1 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0017 | 0.0017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0695 | 0.1672 | 0.3134 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0085 | 0.016 |
Giardia lamblia | Hypothetical protein | 0.0472 | 0.1098 | 0.2427 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0695 | 0.1672 | 0.3134 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0642 | 0.1536 | 0.1536 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0472 | 0.1098 | 0.1098 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Giardia lamblia | Cathepsin L-like protease | 0.0472 | 0.1098 | 0.2427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Echinococcus multilocularis | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Onchocerca volvulus | 0.1389 | 0.3464 | 0.6764 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.2031 | 0.5122 | 0.5122 |
Echinococcus granulosus | cathepsin l1 | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0017 | 0.0017 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2031 | 0.5122 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1114 | 0.2755 | 0.1862 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0695 | 0.1672 | 0.3134 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.1114 | 0.2755 | 0.1862 |
Plasmodium vivax | vivapain-2 | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Encystation-specific protease | 0.0557 | 0.1316 | 0.3027 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | fibroinase | 0.2031 | 0.5122 | 0.5122 |
Plasmodium vivax | unspecified product | 0.0642 | 0.1536 | 0.2863 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0259 | 0.0259 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.0353 | 0.0353 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0713 | 0.1719 | 0.4135 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0472 | 0.1098 | 0.2427 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Giardia lamblia | Cathepsin L-like protease | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | cathepsin B | 0.1539 | 0.3851 | 0.3851 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Onchocerca volvulus | Cathepsin L homolog | 0.0472 | 0.1098 | 0.2143 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1114 | 0.2755 | 0.5377 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0557 | 0.1316 | 0.3027 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.1114 | 0.2755 | 0.529 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0017 | 0.0017 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0713 | 0.1719 | 0.1719 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0472 | 0.1098 | 0.1991 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0472 | 0.1098 | 0.1098 |
Plasmodium vivax | vivapain-3 | 0.1114 | 0.2755 | 0.529 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.008 | 0.0085 | 0.0085 |
Toxoplasma gondii | cathepsin CPL | 0.2031 | 0.5122 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0085 | 0.0085 |
Brugia malayi | cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.5 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0472 | 0.1098 | 0.1991 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0472 | 0.1098 | 0.1991 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0557 | 0.1316 | 0.3027 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0695 | 0.1672 | 0.3134 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0097 | 0.0097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0022 | 0.0022 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1539 | 0.3851 | 0.3851 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0695 | 0.1672 | 0.3134 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 55.6 uM | Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins | ChEMBL. | 19889536 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.