Detailed information for compound 1144602

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 165.207 | Formula: C10H12FN
  • H donors: 1 H acceptors: 0 LogP: 1.52 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC[C@H]1C[C@@H]1c1cccc(c1)F
  • InChi: 1S/C10H12FN/c11-9-3-1-2-7(4-9)10-5-8(10)6-12/h1-4,8,10H,5-6,12H2/t8-,10-/m1/s1
  • InChiKey: ASHHTAGUESNAIP-PSASIEDQSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0159 0.0254
Echinococcus multilocularis GPCR, family 2 0.0017 0.0126 0.0201
Schistosoma mansoni hypothetical protein 0.0146 0.2424 0.3861
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0126 0.0126
Brugia malayi steroid hormone receptor 0.0019 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0479 0.8382 0.8382
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.2893 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0525 0.0768
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Schistosoma mansoni netrin receptor unc5 0.0016 0.0116 0.0185
Brugia malayi MH2 domain containing protein 0.0122 0.1999 0.1999
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0159 0.0254
Loa Loa (eye worm) hypothetical protein 0.0479 0.8382 0.8382
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0164
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0096 0.1531 0.5216
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0361 0.6279 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0126 0.0201
Echinococcus multilocularis jun protein 0.0179 0.3025 0.4817
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0116 0.0116
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0159 0.0159
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0159 0.0254
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0164 0.0189
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0054 0.0785 0.0785
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0084 0.1333 0.2122
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0164 0.5
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0361 0.6279 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0179 0.3025 0.4817
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0785 0.0785
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.008 0.1255 0.1999
Schistosoma mansoni lozenge 0.006 0.0895 0.1426
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0361 0.6279 1
Loa Loa (eye worm) acetyltransferase 0.0146 0.243 0.243
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Schistosoma mansoni hypothetical protein 0.0017 0.0126 0.0201
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0116 0.0185
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0013 0.0046 0.0074
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0013 0.0046 0.0074
Entamoeba histolytica hypothetical protein 0.008 0.1255 1
Brugia malayi ecdysteroid receptor 0.0019 0.0159 0.0159
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.1097 0.1748
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0159 0.0159
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0159 0.0254
Schistosoma mansoni hypothetical protein 0.0037 0.048 0.0765
Schistosoma mansoni chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0026 0.028 0.028
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.1097 0.1748
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0126 0.0201
Brugia malayi hypothetical protein 0.0172 0.2893 0.2893
Loa Loa (eye worm) hypothetical protein 0.0096 0.1531 0.1531
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0159 0.0159
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0159 0.0254
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0159 0.0159
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.028 0.0375
Schistosoma mansoni chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Brugia malayi hypothetical protein 0.008 0.1255 0.1255
Echinococcus multilocularis Ankyrin 0.0017 0.0119 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0159 0.0159
Entamoeba histolytica hypothetical protein 0.008 0.1255 1
Brugia malayi hypothetical protein 0.0479 0.8382 0.8382
Schistosoma mansoni hypothetical protein 0.0017 0.0126 0.0201
Onchocerca volvulus 0.0019 0.0159 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0159 0.0254
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0159 0.0159
Brugia malayi hypothetical protein 0.0141 0.2337 0.2337
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0164 0.0189
Mycobacterium tuberculosis Hypothetical protein 0.0172 0.2893 0.4568
Loa Loa (eye worm) transcriptional regulator 0.0013 0.0046 0.0046
Echinococcus granulosus jun protein 0.0179 0.3025 0.4817
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.1097 0.1097
Echinococcus granulosus chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.048 0.048
Brugia malayi transcriptional regulator, Sir2 family protein 0.0013 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0017 0.0126 0.0201
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0361 0.6279 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.1097 0.1097
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0116 0.0185
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0525 0.3222
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1097 0.1686
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0159 0.0254
Loa Loa (eye worm) hypothetical protein 0.0083 0.1307 0.1307
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0361 0.6279 1
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0013 0.0046 0.0074
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0172 0.2893 0.4568
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0145 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0159 0.0159
Echinococcus granulosus transcription factor Dp 1 0.0041 0.056 0.0892
Brugia malayi Death domain containing protein 0.0016 0.0116 0.0116
Echinococcus granulosus hormone sensitive lipase 0.0226 0.3873 0.6168
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0159 0.0159
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0159 0.0254
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0145 0.0159
Onchocerca volvulus 0.0141 0.2337 0.2686
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0159 0.0254
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0013 0.0046 0.0074
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0116 0.0116
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0159 0.0254
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0159 0.0254
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0785 0.0785
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.028 0.1931
Echinococcus multilocularis chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0159 0.0159
Brugia malayi nuclear receptor NHR-88 0.0019 0.0159 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0159 0.0159
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0361 0.6279 1
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0013 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0016 0.0116 0.0116
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0159 0.0254
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0159 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0159 0.0159
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0159 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0159 0.0159
Mycobacterium ulcerans hypothetical protein 0.0026 0.028 0.0375
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0159 0.0254
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0126 0.0201
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.028 0.0375
Loa Loa (eye worm) sirtuin 4 0.0013 0.0046 0.0046
Echinococcus granulosus nuclear factor of activated T cells 5 0.0084 0.1333 0.2122
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0159 0.0254
Onchocerca volvulus 0.0479 0.8382 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0525 0.3959
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.2357 0.3754
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0096 0.1531 0.2439
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0017 0.0126 0.0126
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0226 0.3873 0.6168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0159 0.0159
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0589 0.1905
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0569 1 1
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0096 0.1531 0.2439
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.243 0.243
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.028 0.0375
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0126 0.0126
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.1097 0.1686
Loa Loa (eye worm) transcriptional regulator 0.0013 0.0046 0.0046
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0096 0.1531 0.5216
Loa Loa (eye worm) hypothetical protein 0.0017 0.0119 0.0119
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0126 0.0201
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0159 0.0254
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.243 0.3871
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0159 0.0052
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0096 0.1531 1
Echinococcus granulosus Ankyrin 0.0017 0.0119 0.0189
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0159 0.0159
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0013 0.0046 0.0074
Schistosoma mansoni chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0096 0.1531 0.5216
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.028 0.0375
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0159 0.0159
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.028 0.0375
Loa Loa (eye worm) hypothetical protein 0.0037 0.048 0.048
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0159 0.0159
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0116 0.0185
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0159 0.0254
Echinococcus multilocularis Protein lozenge 0.006 0.0895 0.1426
Brugia malayi bZIP transcription factor family protein 0.0179 0.3025 0.3025
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0589 0.087
Loa Loa (eye worm) hypothetical protein 0.0174 0.2937 0.2937
Schistosoma mansoni hypothetical protein 0.0016 0.0116 0.0185
Echinococcus granulosus death domain containing protein 0.0016 0.0116 0.0185
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0145 0.0159
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0159 0.0159
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0159 0.0254
Brugia malayi AMP-binding enzyme family protein 0.0026 0.028 0.028
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.028 0.0375
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0159 0.0254
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.243 0.3871
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0361 0.6279 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0159 0.0159
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0145 0.0159
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0159 0.0254
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0159 0.0254
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0159 0.0254
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0159 0.0052
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0159 0.0159
Brugia malayi NAD-dependent deacetylase SIRT1 0.0096 0.1531 0.1531
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0159 0.0254
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0589 0.087
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0159 0.0052
Mycobacterium ulcerans thymidylate synthase 0.0361 0.6279 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.1097 0.1748
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0119 0.0189
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0179 0.3025 0.4817
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.056 0.0892
Onchocerca volvulus 0.0361 0.6279 0.7455
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0159 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0159 0.0159
Onchocerca volvulus 0.0026 0.028 0.0197
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0361 0.6279 1
Schistosoma mansoni jun-related protein 0.0146 0.2424 0.3861
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1097 0.1686
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0164 0.0189
Brugia malayi AMP-binding enzyme family protein 0.0026 0.028 0.028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0589 0.1905
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0096 0.1531 0.5216
Loa Loa (eye worm) hypothetical protein 0.0026 0.028 0.028
Schistosoma mansoni transcription factor LCR-F1 0.008 0.1255 0.1999
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.028 0.1931
Schistosoma mansoni hypothetical protein 0.008 0.1255 0.1999
Brugia malayi Protein kinase domain containing protein 0.0016 0.0116 0.0116
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0159 0.0254
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.028 0.0375
Schistosoma mansoni coup transcription factor 0.0019 0.0159 0.0254
Brugia malayi thymidylate synthase 0.0361 0.6279 0.6279
Echinococcus multilocularis thymidylate synthase 0.0361 0.6279 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.028 0.0375
Entamoeba histolytica hypothetical protein 0.008 0.1255 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0096 0.1531 0.2439
Brugia malayi transcriptional regulator, Sir2 family protein 0.0013 0.0046 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0026 0.028 0.028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0159 0.0159
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0159 0.0254
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.1097 0.8695
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0589 0.087
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.028 0.0375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0159 0.0159
Echinococcus granulosus thymidylate synthase 0.0361 0.6279 1
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0164 0.0189
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.1999 0.1999
Schistosoma mansoni chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Echinococcus multilocularis hormone sensitive lipase 0.0226 0.3873 0.6168
Echinococcus granulosus GPCR family 2 0.0017 0.0126 0.0201
Entamoeba histolytica hypothetical protein 0.008 0.1255 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0026 0.028 0.028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.008 0.1255 0.1999
Brugia malayi Uncoordinated protein 44 0.0016 0.0116 0.0116
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0126 0.0126
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.028 0.0375
Brugia malayi nuclear hormone receptor 0.0019 0.0159 0.0159
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.028 0.1931
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0785 0.0785
Schistosoma mansoni chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.028 0.0375
Loa Loa (eye worm) thymidylate synthase 0.0361 0.6279 0.6279
Brugia malayi transcriptional regulator, Sir2 family protein 0.0013 0.0046 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0159 0.0159
Loa Loa (eye worm) transcriptional regulator 0.0013 0.0046 0.0046
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0159 0.0254
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.028 0.0375
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0226 0.3873 0.6168
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0226 0.3873 0.6168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0164
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0361 0.6279 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1097 0.1686
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0159 0.0254
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.1999 0.1999
Loa Loa (eye worm) hypothetical protein 0.0226 0.3873 0.3873
Loa Loa (eye worm) runx1 0.006 0.0895 0.0895
Schistosoma mansoni chromatin regulatory protein sir2 0.0013 0.0046 0.0074
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0589 0.0938
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0116 0.0185
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0116 0.0185
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0164
Schistosoma mansoni hypothetical protein 0.0017 0.0126 0.0201
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0159 0.0254

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.