Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0064 | 0.0067 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0534 | 1 | 1 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0201 | 0.3391 | 0.3582 |
Brugia malayi | ADAM-TS Spacer 1 family protein | 0.0109 | 0.1566 | 0.1654 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0507 | 0.9467 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0064 | 0.0064 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0 | 0.5 |
Plasmodium falciparum | transporter, putative | 0.003 | 0 | 0.5 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0507 | 0.9467 | 0.9467 |
Brugia malayi | ADAMTS-like protease | 0.0034 | 0.0061 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.2339 | 0.247 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0507 | 0.9467 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0055 | 0.0487 | 0.0514 |
Plasmodium falciparum | amino acid transporter, putative | 0.003 | 0 | 0.5 |
Leishmania major | lanosterol synthase, putative | 0.0353 | 0.6399 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0064 | 0.0067 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0031 | 0.0017 | 0.0018 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0064 | 0.0067 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0433 | 0.8001 | 0.8451 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.084 | 0.0888 |
Brugia malayi | angiogenesis inhibito | 0.0034 | 0.0061 | 0.0064 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0064 | 0.0067 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0064 | 0.0064 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0064 | 0.0064 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0433 | 0.8001 | 0.8001 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0064 | 0.0067 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.3391 | 0.3582 |
Plasmodium vivax | amine transporter, putative | 0.003 | 0 | 0.5 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.003 | 0 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0106 | 0.1509 | 0.1594 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.1509 | 0.1594 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0106 | 0.1509 | 0.1594 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0064 | 0.0067 |
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0046 | 0.0302 | 0.0302 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0231 | 0.3984 | 0.5 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.0433 | 0.8001 | 0.8451 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0 | 0.5 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0046 | 0.0302 | 0.0319 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.003 | 0 | 0.5 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0433 | 0.8001 | 0.8451 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0017 | 0.0018 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0507 | 0.9467 | 0.9467 |
Brugia malayi | Cytochrome P450 family protein | 0.0055 | 0.0487 | 0.0514 |
Echinococcus granulosus | adam | 0.0031 | 0.0017 | 0.0017 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0201 | 0.3391 | 0.3391 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0201 | 0.3391 | 0.3582 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0106 | 0.1509 | 0.1594 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0017 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0064 | 0.0067 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0534 | 1 | 1 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0046 | 0.0302 | 0.0302 |
Brugia malayi | hypothetical protein | 0.0148 | 0.2339 | 0.247 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0201 | 0.3391 | 0.3582 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0433 | 0.8001 | 0.8451 |
Giardia lamblia | Ceramide glucosyltransferase | 0.023 | 0.3961 | 0.5 |
Brugia malayi | Ceramide glucosyltransferase | 0.0507 | 0.9467 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0064 | 0.0067 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.084 | 0.0888 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1566 | 0.1654 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0433 | 0.8001 | 0.8001 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | adam | 0.0031 | 0.0017 | 0.0017 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0064 | 0.0064 |
Trypanosoma brucei | lanosterol synthase | 0.0376 | 0.6852 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.3391 | 0.3582 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0201 | 0.3391 | 0.3391 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0376 | 0.6852 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.008 | 0.0085 |
Onchocerca volvulus | 0.0148 | 0.2339 | 0.247 | |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0507 | 0.9467 | 1 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0376 | 0.6852 | 0.5 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0507 | 0.9467 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0534 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.084 | 0.0888 |
Onchocerca volvulus | Papilin homolog | 0.0035 | 0.008 | 0.0085 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.