Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0121 | 0.0493 | 0.0638 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0064 | 0.007 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.1041 | 0.2042 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0.0064 | 0.0053 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.1598 | 0.7574 | 0.7571 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0525 | 0.2432 | 0.2424 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0235 | 0.1041 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.1212 | 0.1588 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0483 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0021 | 0.0014 | 0.0004 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0046 | 0.0136 | 0.0249 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0136 | 0.0249 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.0067 |
Schistosoma mansoni | lamin | 0.0027 | 0.0043 | 0.0043 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0021 | 0.0014 | 0.0004 |
Echinococcus multilocularis | tumor protein p63 | 0.0336 | 0.1524 | 0.2001 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Echinococcus granulosus | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0047 | 0.0138 | 0.0168 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.1212 | 0.1588 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Plasmodium vivax | pyruvate kinase, putative | 0.0066 | 0.0233 | 0.0289 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1013 | 0.4771 | 0.9436 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0053 | 0.0167 | 0.0202 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0043 | 0.0064 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0066 | 0.0233 | 0.1032 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0064 | 0.0053 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0956 |
Echinococcus multilocularis | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.014 | 0.0585 | 0.0759 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0217 | 0.0407 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.0252 | 0.0241 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.0252 | 0.0319 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0718 | 0.3357 | 0.4425 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0066 | 0.0233 | 0.0222 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0217 | 0.0407 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0116 | 0.0139 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.0355 | 0.0455 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Brugia malayi | hypothetical protein | 0.0235 | 0.1041 | 0.1362 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0021 | 0.0014 | 0.0004 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0047 | 0.0138 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0041 | 0.0059 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Onchocerca volvulus | 0.007 | 0.0252 | 0.4915 | |
Onchocerca volvulus | 0.0049 | 0.015 | 0.2819 | |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.1212 | 0.238 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0077 | 0.0087 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0066 | 0.0233 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0152 | 0.028 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Echinococcus granulosus | dna polymerase eta | 0.0047 | 0.0138 | 0.0168 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.1598 | 0.7574 | 0.7571 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.0498 | 1 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0488 | 0.2253 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.0498 | 1 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.1598 | 0.7574 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0152 | 0.0187 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0525 | 0.2432 | 0.2424 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.0252 | 0.0241 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0638 |
Mycobacterium ulcerans | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0086 | 0.0099 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1013 | 0.4771 | 0.6294 |
Loa Loa (eye worm) | pyruvate kinase | 0.0066 | 0.0233 | 0.0439 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0121 | 0.0493 | 0.0483 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0005 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0806 | 0.3777 | 0.498 |
Echinococcus multilocularis | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.2104 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0217 | 0.0272 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0.0064 | 0.0053 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0021 | 0.0014 | 0.0004 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0116 | 0.0139 |
Plasmodium falciparum | pyruvate kinase | 0.0066 | 0.0233 | 0.0289 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0.0064 | 0.0067 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Leishmania major | pyruvate kinase | 0.0066 | 0.0233 | 0.0222 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0217 | 0.0407 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.2104 | 1 | 1 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0046 | 0.0136 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0233 | 0.0439 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0252 | 0.0478 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.0252 | 0.0319 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.007 | 0.0252 | 0.0319 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0718 | 0.3357 | 0.4425 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0152 | 0.028 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0116 | 0.0139 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0585 | 0.2717 | 0.3579 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.0498 | 0.0966 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0064 | 0.0053 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0116 | 0.0208 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.0252 | 0.0319 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.111 | 0.5235 | 0.6908 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0053 | 0.0167 | 0.0206 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0145 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0138 | 0.0252 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0116 | 0.0139 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0718 | 0.3357 | 0.4425 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.015 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.1013 | 0.4771 | 0.9436 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1073 | 0.5056 | 1 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0483 |
Echinococcus multilocularis | pyruvate kinase | 0.0052 | 0.0166 | 0.0204 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0021 | 0.0014 | 0.0061 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0585 | 0.2717 | 0.3578 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.2104 | 1 | 1 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0066 | 0.0233 | 0.4515 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0043 | 0.0043 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0121 | 0.0493 | 0.0634 |
Leishmania major | pyruvate kinase | 0.0066 | 0.0233 | 0.0222 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0116 | 0.0139 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.0252 | 0.1118 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | pyruvate kinase | 0.0066 | 0.0233 | 0.0439 |
Echinococcus granulosus | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0066 | 0.0233 | 0.0222 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0525 | 0.2432 | 0.2424 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0.0064 | 0.0067 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.007 | 0.0252 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0116 | 0.0208 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0014 | 0.0004 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0066 | 0.0233 | 0.0289 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.007 | 0.0252 | 0.1063 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0043 | 0.0064 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.0105 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0077 | 0.0131 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.015 | 0.0276 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0021 | 0.0014 | 0.0004 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Onchocerca volvulus | 0.0027 | 0.0043 | 0.0608 | |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0031 | 0.0064 | 0.0285 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0043 | 0.0043 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.0252 | 0.0319 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0033 | 0.0072 | 0.0077 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.0384 | 0.0493 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0121 | 0.0493 | 0.0638 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0011 | 0.0049 |
Leishmania major | DNA polymerase eta, putative | 0.0047 | 0.0138 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0021 | 0.0014 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Loa Loa (eye worm) | pyruvate kinase | 0.0066 | 0.0233 | 0.0439 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1073 | 0.5056 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0053 | 0.0167 | 0.074 |
Echinococcus multilocularis | dna polymerase eta | 0.0047 | 0.0138 | 0.0168 |
Leishmania major | DNA polymerase eta, putative | 0.0033 | 0.0072 | 0.0061 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0014 | 0.0061 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0021 | 0.0014 | 0.0004 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0121 | 0.0493 | 0.0638 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0064 | 0.0053 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.0355 | 0.0455 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1013 | 0.4771 | 0.6294 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0121 | 0.0493 | 0.0634 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.0252 | 0.0319 |
Onchocerca volvulus | 0.0048 | 0.0145 | 0.2698 | |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.014 | 0.0585 | 0.0759 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.0067 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0488 | 0.2253 | 1 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.0252 | 0.0319 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0161 | 0.0298 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | oxidoreductase | 0.0021 | 0.0014 | 0.0005 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0021 | 0.0014 | 0.0061 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.1598 | 0.7574 | 0.5 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.1212 | 0.1588 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0217 | 0.0272 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 0.0043 | 0.0043 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0638 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0043 | 0.0043 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1013 | 0.4771 | 0.6294 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0152 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0121 | 0.0493 | 0.0638 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0145 | 0.0177 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0043 | 0.0064 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0047 | 0.0138 | 0.0127 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0043 | 0.0043 |
Schistosoma mansoni | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0021 | 0.0014 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0145 | 0.0177 |
Chlamydia trachomatis | pyruvate kinase | 0.0066 | 0.0233 | 0.0089 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.1598 | 0.7574 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.007 | 0.0252 | 0.0319 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0066 | 0.0233 | 0.0977 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.0384 | 0.0493 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0217 | 0.0272 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0005 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0121 | 0.0493 | 0.0634 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Brugia malayi | hypothetical protein | 0.0122 | 0.0498 | 0.0644 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | DNA polymerase eta | 0.0047 | 0.0138 | 0.0168 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0086 | 0.0099 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0638 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0144 | 0.0176 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0077 | 0.0087 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0066 | 0.0233 | 0.4515 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0021 | 0.0014 | 0.0061 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0086 | 0.0099 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0021 | 0.0014 | 0.0061 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.007 | 0.0252 | 0.1118 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0116 | 0.0139 |
Giardia lamblia | Pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0005 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1013 | 0.4771 | 0.6294 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0235 | 0.1041 | 0.1362 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.1598 | 0.7574 | 0.7571 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0066 | 0.0233 | 0.4515 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.1598 | 0.7574 | 1 |
Onchocerca volvulus | 0.0027 | 0.0043 | 0.0608 | |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.0384 | 0.0493 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0043 | 0.0043 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0121 | 0.0493 | 0.0483 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0034 | 0.0078 | 0.0085 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.0498 | 0.0966 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0252 | 0.0478 |
Giardia lamblia | Pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0956 |
Echinococcus granulosus | lamin | 0.0027 | 0.0043 | 0.0043 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0099 | 0.0391 | 0.0502 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0053 | 0.0167 | 0.0202 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0033 | 0.0072 | 0.0061 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0066 | 0.0233 | 0.0293 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0034 | 0.0078 | 0.0085 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0525 | 0.2432 | 0.2424 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.007 | 0.0252 | 0.0319 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.007 | 0.0252 | 0.1063 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.007 | 0.0252 | 0.0319 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1013 | 0.4771 | 0.9436 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0252 | 0.0478 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.1212 | 0.238 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0116 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0005 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0066 | 0.0233 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0384 | 0.0739 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0034 | 0.0078 | 0.0085 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0217 | 0.0272 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.1598 | 0.7574 | 0.7571 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.0252 | 0.0319 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0638 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.007 | 0.0252 | 0.0319 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.1212 | 0.1588 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.007 | 0.0252 | 0.0319 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.1598 | 0.7574 | 1 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0525 | 0.2432 | 0.3202 |
Echinococcus granulosus | tumor protein p63 | 0.0336 | 0.1524 | 0.2001 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.0384 | 0.0493 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0011 | 0.0049 |
Schistosoma mansoni | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.0252 | 0.0241 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0217 | 0.0272 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0525 | 0.2432 | 0.2424 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.