Detailed information for compound 1153947

Basic information

Technical information
  • TDR Targets ID: 1153947
  • Name: 3-(propan-2-ylamino)propane-1,2-diol
  • MW: 133.189 | Formula: C6H15NO2
  • H donors: 3 H acceptors: 2 LogP: -0.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC(CNC(C)C)O
  • InChi: 1S/C6H15NO2/c1-5(2)7-3-6(9)4-8/h5-9H,3-4H2,1-2H3
  • InChiKey: YKBZGEJJKPNRSI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(Isopropylamino)propane-1,2-diol
  • 6452-57-9
  • EINECS 229-255-8

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0011 0.0011
Loa Loa (eye worm) jmjC domain-containing protein 0.0092 0.0082 0.0082
Brugia malayi Calcitonin receptor-like protein seb-1 0.0112 0.0111 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Giardia lamblia Cathepsin L-like protease 0.0711 0.0977 0.2583
Schistosoma mansoni hypothetical protein 0.0077 0.0059 0.0059
Toxoplasma gondii cathepsin B 0.2642 0.3768 0.8788
Brugia malayi CHD4 protein 0.0038 0.0003 0.0003
Plasmodium vivax unspecified product 0.1639 0.2319 0.5406
Onchocerca volvulus 0.0038 0.0003 0.000000028389
Echinococcus granulosus cathepsin L cysteine proteinase 0.3001 0.4287 0.4287
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Brugia malayi Fli-1 protein 0.0216 0.0262 0.0262
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.3001 0.4287 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.015 0.0166 0.0166
Echinococcus multilocularis chromobox protein 2 0.0038 0.0003 0.0003
Brugia malayi hypothetical protein 0.0038 0.0003 0.0003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0005 0.0005
Trypanosoma cruzi cysteine proteinase, putative 0.1639 0.2319 0.2315
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Plasmodium vivax vivapain-2 0.3001 0.4287 1
Brugia malayi cathepsin L precursor 0.0711 0.0977 0.0977
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0711 0.0977 0.2273
Loa Loa (eye worm) hypothetical protein 0.0711 0.0977 0.0977
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0138 0.0149 0.034
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0038 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0711 0.0977 0.2273
Plasmodium falciparum cysteine proteinase falcipain 3 0.3001 0.4287 1
Toxoplasma gondii cathepsin CPC2 0.0711 0.0977 0.2273
Entamoeba histolytica cysteine protease, putative 0.0711 0.0977 0.2273
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Echinococcus multilocularis cathepsin b 0.6953 1 1
Echinococcus granulosus chromobox protein 2 0.0038 0.0003 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0112 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0711 0.0977 0.2273
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.001 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.3055 0.4364 0.4362
Loa Loa (eye worm) ctsf protein 0.3001 0.4287 0.4287
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0092 0.0082 0.0077
Brugia malayi Ets-domain containing protein 0.0071 0.0052 0.0052
Brugia malayi Cathepsin L-like precursor 0.2073 0.2945 0.2945
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.007 0.0051 0.0051
Brugia malayi F/Y-rich N-terminus family protein 0.0082 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0711 0.0977 0.2273
Brugia malayi Papain family cysteine protease containing protein 0.1639 0.2319 0.2319
Schistosoma mansoni chromobox protein 0.0229 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0043 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.6953 1 1
Loa Loa (eye worm) thioredoxin reductase 0.0099 0.0092 0.0092
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0082 0.0068 0.0068
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0251 0.0312 1
Plasmodium vivax vivapain-2 0.3001 0.4287 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) inositol-1 0.0042 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.015 0.0166 0.0166
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.001 0.0006
Brugia malayi Valyl-tRNA synthetase 0.0038 0.0003 0.0003
Echinococcus multilocularis geminin 0.0376 0.0493 0.0493
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0711 0.0977 0.0977
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.2642 0.3768 0.8631
Brugia malayi cathepsin Z-like cysteine proteinase 0.0711 0.0977 0.0977
Loa Loa (eye worm) hypothetical protein 0.0112 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2073 0.2945 0.6868
Onchocerca volvulus 0.3001 0.4287 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0092 0.0082 0.0177
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.0239 0.0239
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0711 0.0977 0.2273
Brugia malayi Cathepsin L-like precursor 0.0928 0.1291 0.1291
Entamoeba histolytica cysteine proteinase 2 0.1639 0.2319 0.5406
Leishmania major cysteine peptidase A (CPA) 0.3001 0.4287 0.9822
Loa Loa (eye worm) glutathione reductase 0.0099 0.0092 0.0092
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0226 0.0275 0.8818
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.015 0.0166 0.0166
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0038 0.0003 0.0003
Onchocerca volvulus 0.0238 0.0293 0.0678
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0229 0.028 0.028
Brugia malayi Heterochromatin protein 1 0.0229 0.0281 0.0281
Schistosoma mansoni lipoxygenase 0.0109 0.0106 0.0106
Brugia malayi Papain family cysteine protease containing protein 0.0711 0.0977 0.0977
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0005 0.0005
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0711 0.0977 0.2583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1639 0.2319 0.5406
Trypanosoma cruzi cysteine peptidase, putative 0.0928 0.1291 0.1286
Plasmodium falciparum serine repeat antigen 6 0.0711 0.0977 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Onchocerca volvulus 0.0043 0.0011 0.0019
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0711 0.0977 0.0977
Brugia malayi jmjC domain containing protein 0.0819 0.1132 0.1132
Giardia lamblia Cathepsin L-like protease 0.0711 0.0977 0.2583
Giardia lamblia Cysteine protease 0.0711 0.0977 0.2583
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Schistosoma mansoni phd/f-box containing protein 0.0092 0.0082 0.0082
Loa Loa (eye worm) CHromoDomain protein family member 0.0038 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0411 0.0543 0.0543
Loa Loa (eye worm) glutaminase 2 0.0318 0.0408 0.0408
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.019 0.604
Echinococcus granulosus cathepsin b 0.6953 1 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0013 0.0008
Onchocerca volvulus 0.3001 0.4287 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0711 0.0977 0.0977
Echinococcus granulosus thioredoxin glutathione reductase 0.01 0.0093 0.0093
Echinococcus granulosus cathepsin L 0.0711 0.0977 0.0977
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0038 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0711 0.0977 0.2273
Schistosoma mansoni chromobox protein 0.0229 0.0281 0.0281
Plasmodium falciparum serine repeat antigen 9 0.0711 0.0977 0.2273
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0011 0.0011
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0711 0.0977 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0711 0.0977 0.2273
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1639 0.2319 0.5308
Loa Loa (eye worm) hypothetical protein 0.0928 0.1291 0.1291
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0043 0.001 0.0012
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0711 0.0977 0.2273
Schistosoma mansoni hypothetical protein 0.0075 0.0057 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0238 0.0293 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0711 0.0977 0.2273
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0044 0.0095
Echinococcus granulosus cathepsin b 0.6953 1 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0092 0.0082 0.0184
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0711 0.0977 0.2273
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6953 1 1
Mycobacterium ulcerans hypothetical protein 0.0167 0.019 0.451
Schistosoma mansoni glutaminase 0.0318 0.0408 0.0408
Loa Loa (eye worm) papain family cysteine protease containing protein 0.3001 0.4287 0.4287
Brugia malayi fibroinase precursor 0.0711 0.0977 0.0977
Echinococcus multilocularis PHD finger protein rhinoceros 0.0229 0.028 0.028
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0187 0.0218 0.0218
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0187 0.0218 0.0218
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1639 0.2319 0.2315
Brugia malayi Cytochrome P450 family protein 0.0067 0.0045 0.0045
Plasmodium vivax serine-repeat antigen (SERA) 0.0711 0.0977 0.2273
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0075 0.0057 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0251 0.0312 1
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0011 0.0019
Entamoeba histolytica cysteine protease, putative 0.3001 0.4287 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0316 0.0406 0.092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.3001 0.4287 1
Brugia malayi jmjC domain containing protein 0.0092 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Brugia malayi Thioredoxin reductase 0.0099 0.0092 0.0092
Giardia lamblia Cathepsin L precursor 0.0711 0.0977 0.2583
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Echinococcus multilocularis Chromobox protein 3 0.0038 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0077 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0229 0.028 0.028
Schistosoma mansoni chromobox protein 0.0038 0.0003 0.0003
Brugia malayi cathepsin F-like cysteine proteinase 0.0928 0.1291 0.1291
Entamoeba histolytica hypothetical protein 0.0711 0.0977 0.2273
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0165 0.0368
Echinococcus granulosus lysine specific demethylase 6a 0.0092 0.0082 0.0082
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0038 0.0003 0.0003
Plasmodium falciparum cysteine proteinase falcipain 1 0.1639 0.2319 0.5406
Trichomonas vaginalis conserved hypothetical protein 0.0711 0.0977 0.2273
Plasmodium falciparum serine repeat antigen 3 0.0711 0.0977 0.2273
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0112 0.0111 0.0111
Giardia lamblia Cathepsin B precursor 0.2642 0.3768 1
Leishmania major cytochrome p450-like protein 0.0043 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0135 0.0307
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0193 0.0228 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0052 0.0052
Giardia lamblia Cathepsin B precursor 0.0711 0.0977 0.2583
Onchocerca volvulus 0.3001 0.4287 1
Onchocerca volvulus Cathepsin L homolog 0.0711 0.0977 0.2273
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0129 0.0135 0.0135
Brugia malayi AF-10 protein 0.0075 0.0057 0.0057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6953 1 1
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0092 0.0082 0.0082
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0092 0.0082 0.0184
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0226 0.0275 0.8818
Brugia malayi Pre-SET motif family protein 0.14 0.1973 0.1973
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0711 0.0977 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0711 0.0977 0.2273
Entamoeba histolytica cysteine proteinase, putative 0.1639 0.2319 0.5406
Echinococcus granulosus chromobox protein 1 0.0229 0.0281 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.008 0.0181
Loa Loa (eye worm) jmjC domain-containing protein 0.0092 0.0082 0.0082
Giardia lamblia Hypothetical protein 0.0711 0.0977 0.2583
Loa Loa (eye worm) transcription factor SMAD2 0.0265 0.0332 0.0332
Brugia malayi Cathepsin L-like cysteine proteinase 0.2073 0.2945 0.2945
Plasmodium falciparum phd finger protein, putative 0.0229 0.028 0.0648
Trichomonas vaginalis chromobox protein, putative 0.0229 0.0281 0.0648
Schistosoma mansoni hypothetical protein 0.0043 0.0011 0.0011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2642 0.3768 0.3768
Brugia malayi cathepsin Z-like cysteine proteinase 0.0711 0.0977 0.0977
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0038 0.0003 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.0092 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.3001 0.4287 0.4287
Onchocerca volvulus 0.3001 0.4287 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.0239 0.0239
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Entamoeba histolytica cysteine proteinase, putative 0.3001 0.4287 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.2126 0.3023 0.3019
Giardia lamblia Cathepsin B precursor 0.0711 0.0977 0.2583
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0075 0.0057 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0376 0.0493 0.0493
Leishmania major cathepsin L-like protease 0.3001 0.4287 0.9822
Onchocerca volvulus 0.3001 0.4287 1
Trichomonas vaginalis chromobox protein, putative 0.0229 0.0281 0.0648
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0038 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0135 0.0307
Loa Loa (eye worm) hypothetical protein 0.0061 0.0037 0.0037
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.034 0.044 0.1021
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.001 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.001 0.0006
Brugia malayi Cathepsin L-like precursor 0.3001 0.4287 0.4287
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0013 0.0019
Echinococcus granulosus cathepsin l cysteine peptidase 0.3001 0.4287 0.4287
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2642 0.3768 0.3765
Echinococcus granulosus Chromobox protein 3 0.0038 0.0003 0.0003
Onchocerca volvulus 0.1594 0.2253 0.5251
Mycobacterium tuberculosis Probable reductase 0.0226 0.0275 0.8818
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0711 0.0977 0.0977
Brugia malayi MH2 domain containing protein 0.0265 0.0332 0.0332
Entamoeba histolytica cysteine proteinase, putative 0.1639 0.2319 0.5406
Brugia malayi hypothetical protein 0.0038 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.2073 0.2945 0.2945
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0856 0.1186 0.1186
Schistosoma mansoni cathepsin F (C01 family) 0.3001 0.4287 0.4287
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0005 0.0005
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0005 0.0005
Brugia malayi Cathepsin L-like precursor 0.3001 0.4287 0.4287
Loa Loa (eye worm) glutaminase 0.0318 0.0408 0.0408
Giardia lamblia Cysteine protease 0.0711 0.0977 0.2583
Giardia lamblia Cathepsin B precursor 0.2642 0.3768 1
Toxoplasma gondii thioredoxin reductase 0.0099 0.0092 0.0207
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0711 0.0977 0.0977
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.14 0.1973 0.1973
Brugia malayi Cytochrome P450 family protein 0.0043 0.001 0.001
Echinococcus granulosus histone lysine methyltransferase setb 0.0201 0.0239 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0711 0.0977 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0711 0.0977 0.2273
Brugia malayi jmjC domain containing protein 0.0092 0.0082 0.0082
Echinococcus multilocularis peregrin 0.0229 0.028 0.028
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0092 0.0082 0.0077
Schistosoma mansoni cathepsin F (C01 family) 0.3001 0.4287 0.4287
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Brugia malayi latrophilin 2 splice variant baaae 0.0077 0.0059 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.3055 0.4364 0.4362
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) hypothetical protein 0.0201 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.2073 0.2945 0.2945
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.006 0.006
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0092 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0092 0.0082 0.0082
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.001 0.0005
Giardia lamblia Cathepsin L precursor 0.0711 0.0977 0.2583
Leishmania major cathepsin L-like protease 0.3055 0.4364 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0013 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0711 0.0977 0.0977
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0201 0.0239 0.0239
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0075 0.0057 0.0126
Echinococcus granulosus cathepsin l1 0.3001 0.4287 0.4287
Brugia malayi Cathepsin L-like precursor 0.3001 0.4287 0.4287
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Entamoeba histolytica cysteine proteinase, putative 0.3001 0.4287 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0711 0.0977 0.0973
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0711 0.0977 0.0977
Schistosoma mansoni ets-related 0.0216 0.0262 0.0262
Plasmodium vivax serine-repeat antigen (SERA) 0.0711 0.0977 0.2273
Treponema pallidum fructose-bisphosphate aldolase 0.034 0.044 0.5
Schistosoma mansoni polycystin 1-related 0.0043 0.0011 0.0011
Trypanosoma brucei trypanothione reductase 0.0099 0.0092 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0819 0.1132 0.1132
Onchocerca volvulus 0.3001 0.4287 1
Entamoeba histolytica hypothetical protein 0.0038 0.0004 0.0001
Echinococcus multilocularis lysine specific demethylase 6a 0.0092 0.0082 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1639 0.2319 0.5308
Plasmodium vivax JmjC domain containing protein 0.0092 0.0082 0.0184
Onchocerca volvulus Alhambra homolog 0.0229 0.028 0.0648
Loa Loa (eye worm) hypothetical protein 0.0711 0.0977 0.0977
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0819 0.1132 0.1132
Trichomonas vaginalis set domain proteins, putative 0.1594 0.2253 0.5251
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0711 0.0977 0.2273
Brugia malayi Cathepsin L-like precursor 0.3001 0.4287 0.4287
Echinococcus granulosus potassium voltage gated channel subfamily H 0.007 0.0051 0.0051
Mycobacterium tuberculosis Probable oxidoreductase 0.0251 0.0312 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Toxoplasma gondii PHD-finger domain-containing protein 0.0229 0.028 0.0648
Giardia lamblia PHD finger protein 15 0.0229 0.028 0.0733
Leishmania major cathepsin L-like protease 0.3001 0.4287 0.9822
Giardia lamblia Encystation-specific protease 0.0711 0.0977 0.2583
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Echinococcus granulosus phd:f box containing protein 0.0092 0.0082 0.0082
Echinococcus granulosus cathepsin L cysteine protease 0.1639 0.2319 0.2319
Entamoeba histolytica hypothetical protein 0.0038 0.0004 0.0001
Giardia lamblia Cysteine protease 0.0711 0.0977 0.2583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0474 0.0634 0.0634
Loa Loa (eye worm) hypothetical protein 0.6953 1 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0711 0.0977 0.0977
Echinococcus multilocularis JmjC domain containing protein 4 0.0092 0.0082 0.0082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0044 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0013 0.0008
Onchocerca volvulus 0.2073 0.2945 0.6868
Brugia malayi Inositol-1 0.0042 0.001 0.001
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0711 0.0977 0.2273
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.001 0.0016
Giardia lamblia Hypothetical protein 0.0711 0.0977 0.2583
Echinococcus multilocularis cathepsin L cysteine protease 0.3001 0.4287 0.4287
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0099 0.0092 0.2871
Plasmodium falciparum serine repeat antigen 1 0.0711 0.0977 0.2273
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.015 0.0166 0.0166
Loa Loa (eye worm) cathepsin B 0.2642 0.3768 0.3768
Schistosoma mansoni cathepsin F (C01 family) 0.2073 0.2945 0.2945
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Toxoplasma gondii PHD-finger domain-containing protein 0.0229 0.028 0.0648
Echinococcus granulosus PHD finger protein rhinoceros 0.0229 0.028 0.028
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0004 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0057 0.0126
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.001 0.001
Echinococcus granulosus jumonji domain containing 1A 0.0092 0.0082 0.0082
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0092 0.0082 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Leishmania major cathepsin L-like protease 0.3001 0.4287 0.9822
Echinococcus multilocularis RUN 0.0043 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Entamoeba histolytica cysteine proteinase, putative 0.1639 0.2319 0.5406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.3001 0.4287 0.4287
Toxoplasma gondii PHD-finger domain-containing protein 0.0075 0.0057 0.0126
Trypanosoma cruzi major cysteine proteinase, putative 0.0765 0.1055 0.105
Echinococcus granulosus cathepsin L 0.1639 0.2319 0.2319
Loa Loa (eye worm) CYP4Cod1 0.0043 0.001 0.001
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0711 0.0977 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1639 0.2319 0.5406
Onchocerca volvulus 0.0711 0.0977 0.2273
Trichomonas vaginalis glutaminase, putative 0.0318 0.0408 0.0946
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.034 0.044 0.1021
Brugia malayi PHD-finger family protein 0.0229 0.028 0.028
Toxoplasma gondii preprocathepsin c precursor, putative 0.0711 0.0977 0.2273
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0005 0.0004
Brugia malayi Bromodomain containing protein 0.0229 0.028 0.028
Echinococcus granulosus chromobox protein 1 0.0229 0.0281 0.0281
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.001 0.0016
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0711 0.0977 0.2273
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.015 0.0166 0.0166
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.015 0.0166 0.0166
Echinococcus granulosus JmjC domain containing protein 4 0.0092 0.0082 0.0082
Echinococcus multilocularis lysine specific demethylase 5A 0.0345 0.0447 0.0447
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0011 0.0011
Echinococcus multilocularis cathepsin L 0.1639 0.2319 0.2319
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0928 0.1291 0.1291
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0201 0.0239 0.0551
Giardia lamblia Cathepsin B precursor 0.0711 0.0977 0.2583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Echinococcus multilocularis phd:f box containing protein 0.0092 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0711 0.0977 0.2273
Loa Loa (eye worm) jmjC domain-containing protein 0.0092 0.0082 0.0082
Giardia lamblia Cathepsin L precursor 0.0711 0.0977 0.2583
Echinococcus multilocularis cathepsin L 0.0711 0.0977 0.0977
Schistosoma mansoni gabp alpha 0.0071 0.0052 0.0052
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Toxoplasma gondii hypothetical protein 0.0051 0.0023 0.0045
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Entamoeba histolytica hypothetical protein 0.0038 0.0004 0.0001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0345 0.0447 0.0447
Schistosoma mansoni rab6-interacting 0.0043 0.0011 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0149 0.034
Plasmodium vivax SET domain protein, putative 0.0201 0.0239 0.0551
Leishmania major hypothetical protein, conserved 0.0092 0.0082 0.0177
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.001 0.0011
Brugia malayi Pre-SET motif family protein 0.0201 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.2073 0.2945 0.2945
Trypanosoma brucei cysteine peptidase C (CPC) 0.2642 0.3768 0.8631
Trypanosoma cruzi cruzipain precursor, putative 0.0928 0.1291 0.1286
Entamoeba histolytica cysteine protease, putative 0.0711 0.0977 0.2273
Brugia malayi jmjC domain containing protein 0.0092 0.0082 0.0082
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0011 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0226 0.0275 0.8818
Loa Loa (eye worm) hypothetical protein 0.0711 0.0977 0.0977
Echinococcus granulosus cathepsin l1 0.2073 0.2945 0.2945
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0038 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0061 0.0037 0.0037
Entamoeba histolytica cysteine protease, putative 0.0711 0.0977 0.2273
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.001 0.0005
Schistosoma mansoni protein phosphatase 2C 0.0092 0.0082 0.0082
Giardia lamblia Cysteine protease 0.0711 0.0977 0.2583
Plasmodium vivax unspecified product 0.0711 0.0977 0.2273
Trypanosoma cruzi cysteine peptidase, putative 0.3001 0.4287 0.4284
Giardia lamblia Fructose-bisphosphate aldolase 0.034 0.044 0.1157
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0011 0.0011
Brugia malayi chromobox protein homolog 3 0.0129 0.0135 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Schistosoma mansoni jumonji/arid domain-containing protein 0.0345 0.0447 0.0447
Brugia malayi Doublecortin family protein 0.0043 0.0011 0.0011
Brugia malayi hypothetical protein 0.0043 0.0011 0.0011
Echinococcus multilocularis chromobox protein 1 0.0229 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.2073 0.2945 0.2945
Onchocerca volvulus Cathepsin L homolog 0.3001 0.4287 1
Schistosoma mansoni chromobox protein 0.0038 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0129 0.0135 0.0307
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0251 0.0312 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0005 0.0005
Brugia malayi SET domain containing protein 0.0045 0.0014 0.0014
Brugia malayi cathepsin L-like precursor 0.2073 0.2945 0.2945
Schistosoma mansoni loxhd1 0.0043 0.0011 0.0011
Giardia lamblia Cathepsin L precursor 0.0711 0.0977 0.2583
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Brugia malayi Associated with TFs and helicases family protein 0.0038 0.0003 0.0003
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0711 0.0977 0.2273
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0928 0.1291 0.1291
Onchocerca volvulus Cathepsin F homolog 0.3001 0.4287 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0711 0.0977 0.2273
Brugia malayi glutathione reductase 0.0099 0.0092 0.0092
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0928 0.1291 0.1291
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0166 0.0189 0.4492
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.007 0.0051 0.0051
Echinococcus granulosus Chromo domain 0.0038 0.0003 0.0003
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0092 0.0082 0.0184
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0004 0.0004
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0711 0.0977 0.2273
Echinococcus granulosus peregrin 0.0229 0.028 0.028
Brugia malayi Protein cec-1. 0.0038 0.0003 0.0003
Giardia lamblia Cathepsin B precursor 0.0711 0.0977 0.2583
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.001 0.0016
Schistosoma mansoni inositol monophosphatase 0.0042 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.001 0.001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0005 0.0005
Brugia malayi Papain family cysteine protease containing protein 0.0711 0.0977 0.0977
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0711 0.0977 0.0977
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0711 0.0977 0.0977
Plasmodium falciparum serine repeat antigen 7 0.0711 0.0977 0.2273
Loa Loa (eye worm) fibroinase 0.3001 0.4287 0.4287
Brugia malayi Papain family cysteine protease containing protein 0.0711 0.0977 0.0977
Echinococcus multilocularis cysteine protease 0.3001 0.4287 0.4287
Giardia lamblia Cathepsin B precursor 0.0711 0.0977 0.2583
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0711 0.0977 0.0977
Loa Loa (eye worm) jmjC domain-containing protein 0.0345 0.0447 0.0447
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.2642 0.3768 0.8788
Brugia malayi jmjC domain containing protein 0.0092 0.0082 0.0082
Echinococcus multilocularis cathepsin b 0.6953 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0711 0.0977 0.0977
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.001 0.001
Brugia malayi PHD-finger family protein 0.0075 0.0057 0.0057
Echinococcus multilocularis cathepsin l cysteine peptidase 0.3001 0.4287 0.4287
Leishmania major mitochondrial DNA polymerase beta 0.0316 0.0406 0.092
Brugia malayi cathepsin L-like cysteine proteinase 0.0711 0.0977 0.0977
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.015 0.0166 0.0166
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0229 0.028 0.028
Toxoplasma gondii cathepsin CPC1 0.0711 0.0977 0.2273
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0082 0.0082
Leishmania major cathepsin L-like protease 0.3001 0.4287 0.9822
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Schistosoma mansoni inositol monophosphatase 0.0042 0.001 0.001
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.007 0.0051 0.0051
Giardia lamblia Cathepsin L precursor 0.0711 0.0977 0.2583
Leishmania major cathepsin L-like protease 0.3055 0.4364 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0038 0.0003 0.0003
Plasmodium falciparum serine repeat antigen 4 0.0711 0.0977 0.2273
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0011 0.0011
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1639 0.2319 0.2319
Plasmodium falciparum serine repeat antigen 5 0.0711 0.0977 0.2273
Leishmania major cathepsin L-like protease 0.3055 0.4364 1
Echinococcus multilocularis cysteine protease 0.3001 0.4287 0.4287
Giardia lamblia Cathepsin L precursor 0.0711 0.0977 0.2583
Toxoplasma gondii cathepsin CPL 0.3001 0.4287 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6953 1 1
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0149 0.034
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0711 0.0977 0.2273
Loa Loa (eye worm) hypothetical protein 0.0711 0.0977 0.0977
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0711 0.0977 0.2273
Brugia malayi Cathepsin L-like precursor 0.3001 0.4287 0.4287
Schistosoma mansoni hypothetical protein 0.0376 0.0493 0.0493
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.0406 0.0401
Loa Loa (eye worm) cysteine protease 0.3001 0.4287 0.4287
Trypanosoma cruzi cysteine peptidase, putative 0.3055 0.4364 0.4362
Echinococcus multilocularis Chromo domain 0.0038 0.0003 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.3055 0.4364 0.4362
Schistosoma mansoni cathepsin s 0.0928 0.1291 0.1291
Echinococcus multilocularis thioredoxin glutathione reductase 0.01 0.0093 0.0093
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0005 0.0005
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0711 0.0977 0.2273
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0711 0.0977 0.0977
Entamoeba histolytica cysteine protease, putative 0.0711 0.0977 0.2273
Plasmodium falciparum serine repeat antigen 2 0.0711 0.0977 0.2273
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Echinococcus multilocularis chromobox protein 1 0.0229 0.0281 0.0281
Loa Loa (eye worm) MH2 domain-containing protein 0.0265 0.0332 0.0332
Trypanosoma cruzi cysteine peptidase, putative 0.1639 0.2319 0.2315
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0711 0.0977 0.2273
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0092 0.0082 0.0082
Plasmodium vivax hypothetical protein, conserved 0.0229 0.028 0.0648
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Brugia malayi cathepsin F-like cysteine proteinase 0.0711 0.0977 0.0977
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0711 0.0977 0.2583
Schistosoma mansoni jumonji domain containing protein 0.0664 0.0909 0.0909
Plasmodium falciparum cysteine proteinase falcipain 2a 0.3001 0.4287 1
Schistosoma mansoni rab6-interacting 0.0043 0.0011 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.015 0.0166 0.0166
Trypanosoma cruzi cysteine proteinase, putative 0.1639 0.2319 0.2315
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0005 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0226 0.0275 0.8818
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0005 0.0005
Loa Loa (eye worm) helicase 0.0038 0.0003 0.0003
Schistosoma mansoni cathepsin C 0.0711 0.0977 0.0977
Echinococcus granulosus cysteine protease 0.1639 0.2319 0.2319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Plasmodium vivax thioredoxin reductase, putative 0.0099 0.0092 0.0207
Schistosoma mansoni phosphatidylserine receptor 0.0092 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) hypothetical protein 0.0928 0.1291 0.1291
Giardia lamblia Cathepsin B precursor 0.2642 0.3768 1
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Onchocerca volvulus Cathepsin L homolog 0.3001 0.4287 1
Echinococcus granulosus geminin 0.0376 0.0493 0.0493
Plasmodium falciparum glutathione reductase 0.0099 0.0092 0.0207
Entamoeba histolytica cysteine protease, putative 0.0711 0.0977 0.2273
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1639 0.2319 0.2319
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0711 0.0977 0.2273
Brugia malayi hypothetical protein 0.0043 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3001 0.4287 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0711 0.0977 0.2273
Entamoeba histolytica hypothetical protein 0.0038 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0027 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0711 0.0977 0.0977
Schistosoma mansoni cathepsin B (C01 family) 0.0711 0.0977 0.0977
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Plasmodium vivax vivapain-1 0.1639 0.2319 0.5406
Brugia malayi Ets-domain containing protein 0.0071 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0711 0.0977 0.2273
Leishmania major cathepsin L-like protease 0.3001 0.4287 0.9822
Brugia malayi jmjC domain containing protein 0.0345 0.0447 0.0447
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3055 0.4364 1
Plasmodium falciparum serine repeat antigen 8 0.0711 0.0977 0.2273
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0226 0.0275 0.8818
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0711 0.0977 0.2273
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0038 0.0003 0.0003
Mycobacterium ulcerans glutaminase 0.0318 0.0408 1
Brugia malayi Cathepsin L-like precursor 0.3001 0.4287 0.4287
Loa Loa (eye worm) hypothetical protein 0.0075 0.0057 0.0057
Plasmodium vivax glutathione reductase, putative 0.0099 0.0092 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0711 0.0977 0.2273
Entamoeba histolytica cysteine protease, putative 0.1639 0.2319 0.5406
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.0406 0.0401
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.6953 1 1
Schistosoma mansoni hypothetical protein 0.0038 0.0004 0.0004
Loa Loa (eye worm) PHD-finger family protein 0.0229 0.028 0.028
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0004 0.0004
Brugia malayi Cytochrome P450 family protein 0.0043 0.001 0.001
Entamoeba histolytica cysteine proteinase, putative 0.2073 0.2945 0.6868
Loa Loa (eye worm) heterochromatin protein 1 0.0229 0.0281 0.0281
Echinococcus granulosus lysine specific demethylase 5A 0.0345 0.0447 0.0447
Echinococcus multilocularis jumonji domain containing protein 0.0319 0.041 0.041
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0166 0.0189 0.6016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) hypothetical protein 0.3001 0.4287 0.4287
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0075 0.0057 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Schistosoma mansoni lipoxygenase 0.0187 0.0218 0.0218
Brugia malayi glutaminase DH11.1 0.0318 0.0408 0.0408
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.0165 0.0368
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0711 0.0977 0.2273
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0052 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.008 0.0181
Leishmania major trypanothione reductase 0.0099 0.0092 0.02
Plasmodium falciparum thioredoxin reductase 0.0099 0.0092 0.0207
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.044 0.1021
Trypanosoma brucei cytochrome P450, putative 0.0043 0.001 0.0013
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0711 0.0977 0.2273
Onchocerca volvulus 0.3001 0.4287 1
Onchocerca volvulus 0.0043 0.0011 0.0019
Entamoeba histolytica cysteine proteinase 1, putative 0.1639 0.2319 0.5406
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1639 0.2319 0.2319
Brugia malayi Papain family cysteine protease containing protein 0.1639 0.2319 0.2319
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.001 0.5
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0166 0.0189 0.6016
Echinococcus multilocularis jumonji domain containing 1A 0.0092 0.0082 0.0082
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0165 0.016
Entamoeba histolytica cysteine proteinase, putative 0.1639 0.2319 0.5406
Echinococcus granulosus jumonji domain containing protein 0.0319 0.041 0.041
Trypanosoma cruzi cysteine protease, putative 0.1639 0.2319 0.2315
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0711 0.0977 0.2583
Brugia malayi M-phase phosphoprotein, mpp8 0.0038 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2073 0.2945 0.6868
Brugia malayi Papain family cysteine protease containing protein 0.3001 0.4287 0.4287
Schistosoma mansoni cathepsin S (C01 family) 0.0711 0.0977 0.0977
Loa Loa (eye worm) hypothetical protein 0.0043 0.0011 0.0011
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0038 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3001 0.4287 1
Loa Loa (eye worm) fli-1 protein 0.0216 0.0262 0.0262
Echinococcus multilocularis cathepsin L cysteine protease 0.3001 0.4287 0.4287
Plasmodium vivax vivapain-3 0.1639 0.2319 0.5406
Echinococcus granulosus RUN 0.0043 0.0011 0.0011
Onchocerca volvulus 0.0101 0.0095 0.0214
Mycobacterium tuberculosis Probable dehydrogenase 0.0226 0.0275 0.8818
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.015 0.0166 0.0166
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0201 0.0239 0.0239
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0711 0.0977 0.2583
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0711 0.0977 0.0977
Plasmodium vivax unspecified product 0.0928 0.1291 0.3006

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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