Detailed information for compound 1159476

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 349.453 | Formula: C19H19N5S
  • H donors: 1 H acceptors: 1 LogP: 3.98 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)sc(n2)c1ccc(cc1)N1C=NC(=NC1(C)C)N
  • InChi: 1S/C19H19N5S/c1-12-4-9-15-16(10-12)25-17(22-15)13-5-7-14(8-6-13)24-11-21-18(20)23-19(24,2)3/h4-11H,1-3H3,(H2,20,23)
  • InChiKey: BAEPVIZSWUFNAQ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi CXXC zinc finger family protein 0.0089 0.0581 0.1148
Echinococcus granulosus Peptidase C54 0.0181 0.1271 0.251
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0238 0.1112
Leishmania major DNA damage repair protein, putative 0.0023 0.0081 0.0324
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.004 0.0079
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0156 0.0974
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0098 0.0143
Echinococcus multilocularis expressed conserved protein 0.0094 0.0615 0.1008
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0425 0.1912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0393 0.0776
Echinococcus multilocularis voltage gated potassium channel subunit 0.0019 0.005 0.0063
Trichomonas vaginalis endoplasmin, putative 0.0034 0.0164 0.0764
Plasmodium falciparum basic transcription factor 3b, putative 0.0072 0.0449 0.3514
Schistosoma mansoni hypothetical protein 0.0142 0.0972 0.192
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0105 0.0436
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Onchocerca volvulus 0.0064 0.0394 0.0394
Onchocerca volvulus 0.0018 0.0045 0.0045
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0045 0.0187
Schistosoma mansoni aldo-keto reductase 0.0064 0.0394 0.0777
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0703 0.3278
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0183 0.1287 0.1287
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0017 0.004 0.0079
Echinococcus granulosus endoplasmin 0.0044 0.0238 0.0471
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0088
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0058 0.0272
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0167 0.0722
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0045 0.001
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Plasmodium falciparum aldo-keto reductase, putative 0.0019 0.005 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0449 0.2094
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.009 0.0108
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0405 0.1821
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis peregrin 0.0039 0.02 0.0314
Echinococcus granulosus dna polymerase eta 0.0099 0.0652 0.1288
Giardia lamblia Protein tyrosine phosphatase 0.0017 0.004 0.0002
Schistosoma mansoni kinase 0.0056 0.0328 0.0648
Schistosoma mansoni alpha glucosidase 0.0036 0.0181 0.0357
Schistosoma mansoni hypothetical protein 0.0041 0.022 0.0435
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0058 0.0115
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.009 0.0421
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0181 0.0843
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0405 0.0657
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Trypanosoma brucei DNA polymerase IV, putative 0.0093 0.0611 0.2774
Trypanosoma cruzi aldo/keto reductase, putative 0.0064 0.0394 0.1769
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0317 0.051
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0118 0.0233
Loa Loa (eye worm) hypothetical protein 0.0071 0.0443 0.0443
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.1132 0.1872
Mycobacterium tuberculosis Conserved hypothetical protein 0.0073 0.0461 0.0905
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0064 0.0394 0.1835
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Schistosoma mansoni hypothetical protein 0.0083 0.0531 0.1049
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0044 0.0238 0.0429
Echinococcus granulosus peregrin 0.0039 0.02 0.0394
Plasmodium falciparum heat shock protein 90 0.0047 0.026 0.1958
Toxoplasma gondii Hsp90 domain-containing protein 0.0177 0.1238 1
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0017 0.004 0.004
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.004 0.0185
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0085 0.0378
Echinococcus granulosus tar DNA binding protein 0.0064 0.0393 0.0776
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0045 0.0055
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0156 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0045 0.0208
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.0355 0.0701
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.009 0.0421
Trypanosoma cruzi aldo-keto reductase 0.0064 0.0394 0.1769
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0181 0.1271 0.582
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0079
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.004 0.0135
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Schistosoma mansoni hypothetical protein 0.0029 0.0128 0.0253
Onchocerca volvulus 0.0048 0.0268 0.0268
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.005 0.0232
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0207 0.1464 0.1464
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.004 0.0135
Loa Loa (eye worm) hypothetical protein 0.0043 0.0232 0.0232
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0017 0.004 0.0047
Toxoplasma gondii exonuclease III APE 0.0019 0.0051 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0393 0.0636
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.004 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0098 0.0098
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0062 0.0287
Loa Loa (eye worm) oxidoreductase 0.0064 0.0394 0.0394
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0017 0.004 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.009 0.0369
Schistosoma mansoni tyrosine kinase 0.0059 0.0355 0.0701
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Trichomonas vaginalis helicase, putative 0.002 0.0062 0.0287
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Onchocerca volvulus 0.0017 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis protein dispatched 1 0.0049 0.0277 0.0443
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0156 0.0309
Loa Loa (eye worm) hypothetical protein 0.0099 0.0652 0.0652
Brugia malayi Hsp90 protein 0.0031 0.0142 0.0281
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0531 0.1049
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0071 0.044 0.1985
Onchocerca volvulus 0.0064 0.0394 0.0394
Trichomonas vaginalis aldo/keto reductase, putative 0.0064 0.0394 0.1835
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0056 0.0211
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0661 0.1305
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0017 0.004 0.0079
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0047
Schistosoma mansoni hypothetical protein 0.0041 0.022 0.0435
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0036 0.0178 0.0352
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0983 0.1941
Trypanosoma cruzi Heat shock protein 83, putative 0.0047 0.026 0.1152
Onchocerca volvulus 0.0089 0.0581 0.0581
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.004 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0098 0.0098
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0125 0.0247
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0672 0.1328
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Loa Loa (eye worm) hypothetical protein 0.0179 0.1253 0.1253
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0268 0.0528
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.004 0.0079
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0017 0.004 0.0187
Entamoeba histolytica peptidase, C54 family 0.0071 0.044 0.2053
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0019 0.005 0.005
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0181 0.0843
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.026 0.1046
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0071 0.044 0.1985
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0401 0.065
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0405 0.08
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Mycobacterium tuberculosis Conserved protein 0.0019 0.005 0.0027
Brugia malayi Pre-SET motif family protein 0.0033 0.0156 0.0309
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0011 0.0049
Schistosoma mansoni DNA helicase recq1 0.002 0.0058 0.0115
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.004 0.0146
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0017 0.004 0.0137
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.004 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0393 0.0776
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Onchocerca volvulus Huntingtin homolog 0.0252 0.1801 0.1801
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Brugia malayi hypothetical protein 0.0017 0.004 0.0079
Onchocerca volvulus 0.0064 0.0394 0.0394
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0285 0.0564
Echinococcus granulosus insulin receptor 0.013 0.0888 0.1754
Onchocerca volvulus 0.0018 0.0045 0.0045
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0098 0.0193
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0687 0.5064 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0859 0.0859
Entamoeba histolytica peptidase, C54 family 0.0071 0.044 0.2053
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Onchocerca volvulus 0.0017 0.004 0.004
Onchocerca volvulus 0.0064 0.0394 0.0394
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0401 0.0792
Entamoeba histolytica hypothetical protein 0.0072 0.0449 0.2094
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0098 0.0193
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0661 0.1305
Onchocerca volvulus 0.0017 0.004 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0181 0.0843
Loa Loa (eye worm) TK/EGFR protein kinase 0.0059 0.0355 0.0355
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0136 0.0269
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0982 0.4487
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.009 0.0427
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0051 0.01
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0045 0.0208
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0317 0.0626
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0017 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Onchocerca volvulus 0.0017 0.004 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0011 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0128 0.0875
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0017 0.004 0.0079
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0654 0.1292
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0071 0.044 0.3344
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0183 0.1287 0.5893
Trypanosoma brucei aldo-keto reductase, putative 0.0064 0.0394 0.1769
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.009 0.0421
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0113 0.0528
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.2145 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0105 0.0544
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0058 0.0272
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0051 0.0185
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.059 0.1164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.01 0.0661 0.308
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0314 0.1403
Onchocerca volvulus 0.0064 0.0394 0.0394
Schistosoma mansoni tyrosine kinase 0.013 0.0888 0.1754
Plasmodium vivax heat shock protein 86, putative 0.0047 0.026 0.1958
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0064 0.0394 0.0777
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0318 0.1482
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0098 0.0098
Loa Loa (eye worm) TK/INSR protein kinase 0.013 0.0888 0.0888
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0534 0.0871
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0106 0.0703 0.1388
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.009 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.034 0.1519
Echinococcus multilocularis aldo keto reductase 0.0064 0.0394 0.0638
Onchocerca volvulus 0.0017 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0166 0.1157 0.2285
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.004 0.0146
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0268 0.0268
Trichomonas vaginalis aldo/keto reductase, putative 0.0064 0.0394 0.1835
Entamoeba histolytica aldose reductase, putative 0.0064 0.0394 0.1835
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0045 0.0016
Trichomonas vaginalis DNA polymerase eta, putative 0.01 0.0661 0.308
Brugia malayi Protein kinase domain containing protein 0.0183 0.1287 0.2541
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0167 0.1193
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0767 0.1557
Echinococcus multilocularis GPCR, family 2 0.0066 0.0401 0.065
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0064 0.0394 0.3613
Loa Loa (eye worm) hypothetical protein 0.0024 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0044 0.0238 0.1983
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Mycobacterium leprae Conserved hypothetical protein 0.0046 0.0253 0.214
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0088
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Echinococcus granulosus cysteine protease atg4b 0.0181 0.1271 0.251
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0071 0.044 0.1985
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0088
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Trypanosoma cruzi DNA polymerase eta, putative 0.0099 0.0652 0.2964
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Echinococcus granulosus protein tyrosine phosphatase n9 0.0017 0.004 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.0654 0.0654
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.004 0.0079
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0081 0.0159
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0141 0.0278
Echinococcus granulosus aldo keto reductase 0.0064 0.0394 0.0777
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0285 0.0529
Entamoeba histolytica protein kinase, putative 0.0183 0.1287 0.5998
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0079
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0767 0.1557
Plasmodium falciparum thioredoxin reductase 0.0017 0.004 0.0146
Onchocerca volvulus 0.0018 0.0045 0.0045
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0982 0.4487
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0058 0.022
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Toxoplasma gondii NAC domain-containing protein 0.0072 0.0449 0.3417
Entamoeba histolytica protein kinase, putative 0.0183 0.1287 0.5998
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0058 0.0154
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0268 0.0528
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0051 0.0052
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0079
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0064 0.0394 0.1835
Onchocerca volvulus 0.0018 0.0045 0.0045
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0017 0.004 0.0187
Onchocerca volvulus 0.0017 0.004 0.004
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0045 0.0088
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.004 0.0185
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0058 0.0058
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0401 0.0401
Schistosoma mansoni cpg binding protein 0.0089 0.0581 0.1148
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Mycobacterium tuberculosis Probable reductase 0.0114 0.0767 0.1557
Leishmania major heat shock protein, putative 0.0031 0.0142 0.0609
Entamoeba histolytica protein kinase domain containing protein 0.0183 0.1287 0.5998
Leishmania major trypanothione reductase 0.005 0.0285 0.1269
Loa Loa (eye worm) hypothetical protein 0.0083 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.011
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0051 0.0185
Toxoplasma gondii heat shock protein HSP90 0.0047 0.026 0.1838
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0232 0.0232
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.004 0.0079
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.004 0.0146
Entamoeba histolytica peptidase, C54 family 0.0181 0.1271 0.5925
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.0355 0.0701
Brugia malayi RNA binding protein 0.0064 0.0393 0.0776
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0982 0.4487
Plasmodium falciparum phd finger protein, putative 0.0029 0.0128 0.0875
Onchocerca volvulus 0.0018 0.0045 0.0045
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0181 0.0843
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0019 0.005 0.0098
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.005 0.0232
Schistosoma mansoni cpg binding protein 0.0095 0.0619 0.1223
Toxoplasma gondii hypothetical protein 0.0049 0.0275 0.1964
Echinococcus granulosus bloom syndrome protein 0.002 0.0058 0.0115
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Brugia malayi Flap endonuclease-1 0.0026 0.0105 0.0207
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0111 0.0739 0.146
Loa Loa (eye worm) hypothetical protein 0.0066 0.0402 0.0402
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.0654 0.1292
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0093 0.0183
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0051 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.004 0.0047
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0098 0.0485
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Brugia malayi Calcitonin receptor-like protein seb-1 0.0207 0.1464 0.2891
Onchocerca volvulus 0.024 0.171 0.171
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0156 0.0309
Trypanosoma brucei heat shock protein 90, putative 0.0047 0.026 0.1152
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.004 0.0046
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0167 0.0722
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0317 0.0626
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0285 0.1269
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0703 0.1388
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0031 0.0142 0.0281
Loa Loa (eye worm) hypothetical protein 0.0152 0.1049 0.1049
Trypanosoma brucei heat shock protein 90, putative 0.0047 0.026 0.1152
Echinococcus multilocularis lamin 0.0058 0.0342 0.0551
Trypanosoma brucei DNA polymerase IV, putative 0.01 0.0661 0.3003
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.1132 0.2236
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0983 0.1623
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0019 0.005 0.0181
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0425 0.1912
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0531 0.0867
Schistosoma mansoni hypothetical protein 0.0166 0.1157 0.2285
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0045 0.0055
Echinococcus multilocularis aldehyde reductase 0.0046 0.0253 0.0403
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0081 0.0324
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0011 0.0049
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.2176 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.2921 0.4861
Schistosoma mansoni SET domain protein 0.0019 0.005 0.0099
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0183 0.1287 0.5893
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0401 0.065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0019 0.005 0.0083
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1495 0.1495
Echinococcus granulosus GPCR family 2 0.0066 0.0401 0.0792
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0405 0.08
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0081 0.0324
Giardia lamblia Aldose reductase 0.0064 0.0394 0.1681
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0081 0.0324
Schistosoma mansoni alpha-glucosidase 0.014 0.0962 0.19
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0228 0.1005
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Schistosoma mansoni tyrosine kinase 0.0058 0.0347 0.0685
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0045 0.0088
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0461 0.0911
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0045 0.0158
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0045 0.0088
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0181 0.0843
Schistosoma mansoni intermediate filament proteins 0.0058 0.0342 0.0675
Schistosoma mansoni hypothetical protein 0.0066 0.0401 0.0792
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0181 0.1271 0.582
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0158
Brugia malayi CHE-14 protein 0.0043 0.0232 0.0458
Mycobacterium ulcerans hypothetical protein 0.0024 0.009 0.0108
Loa Loa (eye worm) hypothetical protein 0.0024 0.009 0.009
Brugia malayi serine/threonine-protein kinase plk-2 0.0106 0.0703 0.1388
Trypanosoma brucei unspecified product 0.0051 0.029 0.129
Entamoeba histolytica cysteine protease, putative 0.0018 0.0045 0.0208
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0062 0.0287
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0181 0.1271 0.5925
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0088
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0268 0.0528
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0361 0.0361
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0687 0.5064 0.8443
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0058 0.0154
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0425 0.1912
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0105 0.031
Schistosoma mansoni tyrosine kinase 0.0059 0.0355 0.0701
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0017 0.004 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.004 0.0079
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0093 0.0183
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.009 0.0369
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0017 0.004 0.0079
Schistosoma mansoni pcd6 interacting protein-related 0.0017 0.004 0.0079
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0051 0.0029
Echinococcus multilocularis heat shock protein 0.0047 0.026 0.0414
Onchocerca volvulus 0.0017 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0401 0.0792
Plasmodium falciparum flap endonuclease 1 0.0026 0.0105 0.0683
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0196 0.0308
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0051 0.01
Entamoeba histolytica recQ family helicase, putative 0.002 0.0058 0.0272
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0051 0.0236
Onchocerca volvulus Huntingtin homolog 0.0252 0.1801 0.1801
Onchocerca volvulus 0.0017 0.004 0.004
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0051 0.0064
Schistosoma mansoni pol-related 0.0064 0.0394 0.0777
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0085 0.0215
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0081 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.028 0.1246
Loa Loa (eye worm) hypothetical protein 0.0058 0.0342 0.0342
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.005 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0285 0.0285
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0268 0.0528
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0661 0.1084
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.004 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0401 0.0792
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Echinococcus granulosus dual specificity 0.0183 0.1287 0.2541
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0085 0.0518
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0045 0.0055
Brugia malayi Furin-like cysteine rich region family protein 0.0059 0.0355 0.0701
Echinococcus multilocularis cysteine protease atg4b 0.0181 0.1271 0.2104
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0181 0.0843
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0098 0.0485
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0181 0.0786
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0317 0.051
Giardia lamblia Aldose reductase 0.0064 0.0394 0.1681
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0164 0.0325
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.2176 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0252 0.1801 0.1801
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0285 0.0457
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0062 0.0287
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0405 0.08
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0071 0.044 0.1985
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0531 0.1049
Schistosoma mansoni aldo-keto reductase 0.0064 0.0394 0.0777
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Entamoeba histolytica deoxycytidyl transferase, putative 0.0073 0.0461 0.215
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0105 0.0489
Plasmodium falciparum glutathione reductase 0.0017 0.004 0.0146
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.0641 0.4725 1
Brugia malayi ImpB/MucB/SamB family protein 0.0099 0.0652 0.1288
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0128 0.0739
Echinococcus granulosus geminin 0.0166 0.1157 0.2285
Plasmodium vivax heat shock protein 90, putative 0.0031 0.0142 0.099
Mycobacterium ulcerans hypothetical protein 0.0023 0.0081 0.0087
Loa Loa (eye worm) hypothetical protein 0.0049 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0268 0.0427
Entamoeba histolytica hypothetical protein 0.0111 0.0739 0.3447
Onchocerca volvulus 0.0017 0.004 0.004
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0044 0.0238 1
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0017 0.004 0.0079
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0098 0.0193
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0093 0.0135
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0158
Schistosoma mansoni hypothetical protein 0.0294 0.2115 0.4175
Onchocerca volvulus 0.0024 0.009 0.009
Trypanosoma cruzi aldo/keto reductase, putative 0.0019 0.005 0.0181
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0633 0.466 0.9202
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.005 0.0232
Leishmania major hypothetical protein, conserved 0.0025 0.0098 0.0403
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0081 0.0324
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0531 0.1049
Brugia malayi jmjC domain containing protein 0.0099 0.0654 0.1292
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0088 0.0571 0.0571
Schistosoma mansoni hypothetical protein 0.0066 0.0401 0.0792
Treponema pallidum heat shock protein 90 0.0044 0.0238 0.0944
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Leishmania major basic transcription factor 3a, putative 0.0072 0.0449 0.2025
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.004 0.0047
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0064 0.0394 0.0777
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0017 0.004 0.0079
Entamoeba histolytica peptidase, C54 family 0.0071 0.044 0.2053
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0058 0.0272
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0232 0.0367
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0058 0.0115
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0196 0.0388
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0687 0.5064 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.009 0.0108
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.01 0.0661 0.0661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0393 0.0776
Leishmania major hypothetical protein, conserved 0.0034 0.0167 0.0722
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0058 0.0088
Brugia malayi Endoplasmin precursor 0.0047 0.026 0.0513
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Giardia lamblia DNA damage repair protein 0.0023 0.0081 0.0195
Echinococcus granulosus lamin 0.0058 0.0342 0.0675
Loa Loa (eye worm) hypothetical protein 0.0252 0.1801 0.1801
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Onchocerca volvulus Alhambra homolog 0.0029 0.0128 0.0128
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0158
Loa Loa (eye worm) protein tyrosine phosphatase 0.0017 0.004 0.004
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0661 0.3003
Brugia malayi jmjC domain containing protein 0.0025 0.0098 0.0193
Entamoeba histolytica hypothetical protein 0.0111 0.0739 0.3447
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0105 0.0489
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0045 0.0088
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Echinococcus granulosus hypothetical protein 0.0064 0.0394 0.0777
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.004 0.0079
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0051 0.0548
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0005 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Schistosoma mansoni autophagin-1 (C54 family) 0.0181 0.1271 0.251
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.004 0.0079
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0317 0.0626
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0181 0.0843
Mycobacterium ulcerans DNA polymerase IV 0.01 0.0661 0.1326
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0739 0.146
Mycobacterium ulcerans hypothetical protein 0.0019 0.005 0.0021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.1002 0.2053
Echinococcus multilocularis transcription factor btf3 0.0072 0.0449 0.0731
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0105 0.0436
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0167 0.0722
Echinococcus multilocularis Peptidase C54 0.0181 0.1271 0.2104
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0534 0.1054
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.038 0.1705
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.059 0.1164
Leishmania major tyrosine specific protein phosphatase, putative 0.0017 0.004 0.0137
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0017 0.004 0.0079
Loa Loa (eye worm) oxidoreductase 0.0064 0.0394 0.0394
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Trichomonas vaginalis aldo/keto reductase, putative 0.0064 0.0394 0.1835
Trichomonas vaginalis heat shock protein, putative 0.0047 0.026 0.1212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Loa Loa (eye worm) hypothetical protein 0.0033 0.0156 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0017 0.004 0.0047
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0531 0.1049
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0014 0.0012 0.0024
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0047
Brugia malayi Protein kinase domain containing protein 0.0633 0.466 0.9202
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.004 0.0135
Echinococcus granulosus phd:f box containing protein 0.0025 0.0098 0.0193
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0017 0.004 0.0079
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0342 0.0342
Loa Loa (eye worm) glutathione reductase 0.005 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0024 0.009 0.009
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0203 0.04
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0081 0.0324
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0106 0.0703 0.3198
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0017 0.004 0.0079
Plasmodium vivax glutathione reductase, putative 0.005 0.0285 0.2167
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.0113 0.0751
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Schistosoma mansoni tyrosine kinase 0.0058 0.0347 0.0685
Plasmodium falciparum heat shock protein 90, putative 0.0177 0.1238 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0011 0.0049
Loa Loa (eye worm) hypothetical protein 0.0152 0.1049 0.1049
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0017 0.004 0.0079
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.026 0.1152
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0181 0.1271 0.5925
Echinococcus granulosus aldo keto reductase 0.0064 0.0394 0.0777
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0093 0.0135
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.009 0.0369
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Echinococcus multilocularis 0.0017 0.004 0.0047
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0859 0.0859
Echinococcus granulosus dnaJ subfamily B 0.0401 0.2921 0.5768
Giardia lamblia Kinase, PLK 0.0106 0.0703 0.3151
Brugia malayi jmjC domain containing protein 0.0025 0.0098 0.0193
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0036 0.0178 0.0278
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0017 0.004 0.0079
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0393 0.0393
Brugia malayi Protein kinase domain containing protein 0.013 0.0888 0.1754
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0045 0.0187
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0085 0.2277
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Plasmodium vivax basic transcription factor 3b, putative 0.0072 0.0449 0.3514
Brugia malayi Protein-tyrosine phosphatase 0.0017 0.004 0.0079
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0098 0.0403
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0064 0.0394 0.1769
Schistosoma mansoni eyes absent homolog 0.0088 0.0571 0.1127
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0158
Schistosoma mansoni transcription factor btf3 0.0072 0.0449 0.0887
Mycobacterium ulcerans hypothetical protein 0.0106 0.0709 0.1428
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0425 0.1912
Loa Loa (eye worm) endoplasmin 0.0047 0.026 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0181 0.0786
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0105 0.0436
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.004 0.0047
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.1002 1
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0098 0.0193
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Echinococcus multilocularis hypothetical protein 0.0017 0.004 0.0047
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.008 0.0511 0.231
Onchocerca volvulus 0.0017 0.004 0.004
Loa Loa (eye worm) oxidoreductase 0.0064 0.0394 0.0394
Entamoeba histolytica peptidase, C54 family 0.0071 0.044 0.2053
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Plasmodium falciparum glutathione reductase 0.005 0.0285 0.2167
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0059 0.0355 0.0701
Loa Loa (eye worm) hypothetical protein 0.0179 0.1253 0.1253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0062 0.0287
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0017 0.004 0.0079
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.0209 0.0918
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0181 0.1271 0.582
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0214 0.0423
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.2145 1
Onchocerca volvulus 0.0017 0.004 0.004
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0098 0.0403
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0073 0.0461 0.0751
Brugia malayi MH2 domain containing protein 0.0126 0.0859 0.1696
Loa Loa (eye worm) ICD-1 protein 0.0072 0.0449 0.0449
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Schistosoma mansoni ap endonuclease 0.0019 0.0051 0.01
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0045 0.0187
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0167 0.0722
Toxoplasma gondii thioredoxin reductase 0.005 0.0285 0.205
Schistosoma mansoni jumonji domain containing protein 0.0135 0.092 0.1817
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0051 0.0236
Giardia lamblia Heat shock protein HSP 90-alpha 0.004 0.0209 0.0806
Onchocerca volvulus 0.0017 0.004 0.004
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Echinococcus granulosus aldo keto reductase 0.0064 0.0394 0.0777
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0156 0.0309
Brugia malayi Muscleblind-like protein 0.0152 0.1049 0.2072
Plasmodium falciparum cysteine protease ATG4, putative 0.0071 0.044 0.3441
Echinococcus granulosus cathepsin l1 0.0018 0.0045 0.0088
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0661 0.308
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0863 0.1761
Onchocerca volvulus 0.0017 0.004 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.009 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0062 0.0287
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.059 0.1164
Leishmania major cathepsin L-like protease 0.0069 0.0425 0.1912
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0105 0.0683
Echinococcus granulosus heat shock protein 0.0047 0.026 0.0513
Schistosoma mansoni tyrosine kinase 0.0059 0.0355 0.0701
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0048 0.0272 0.1938
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.004 0.0146
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0811 0.5996 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0019
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.004 0.0135
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0167 0.1062
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0085 0.0344
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0167 0.0167
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0158
Echinococcus multilocularis bloom syndrome protein 0.002 0.0058 0.0077
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0661 0.3003
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0232 0.0458
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0181 0.1177
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0044 0.0238 0.1052
Trypanosoma cruzi heat shock protein, putative 0.0031 0.0142 0.0609
Schistosoma mansoni hypothetical protein 0.0041 0.022 0.0435
Brugia malayi hypothetical protein 0.0017 0.004 0.0079
Echinococcus multilocularis muscleblind protein 1 0.0152 0.1049 0.1734
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.059 0.1164
Brugia malayi polk-prov protein 0.0049 0.028 0.0554
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0051 0.0023
Leishmania major cathepsin L-like protease 0.0069 0.0425 0.1912
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Schistosoma mansoni lamin 0.0058 0.0342 0.0675
Leishmania major DNA polymerase kappa, putative 0.0023 0.0081 0.0324
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0232 0.0458
Mycobacterium ulcerans DNA polymerase IV 0.01 0.0661 0.1326
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.004 0.0135
Plasmodium falciparum endoplasmin, putative 0.0034 0.0164 0.1167
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0058 0.022
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Onchocerca volvulus 0.0058 0.0342 0.0342
Brugia malayi hypothetical protein 0.0088 0.0571 0.1127
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.1132 0.1132
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0073 0.0461 0.0911
Giardia lamblia DINP protein human, muc B family 0.008 0.0511 0.2237
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0045 0.0158
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0064 0.0394 0.1769
Entamoeba histolytica hypothetical protein 0.0183 0.1287 0.5998
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Trichomonas vaginalis pten, drome, putative 0.0017 0.004 0.0187
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0183 0.1287 0.5893
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0045 0.1085
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0085 0.0344
Trypanosoma brucei DNA polymerase IV, putative 0.01 0.0661 0.3003
Brugia malayi jmjC domain containing protein 0.0025 0.0098 0.0193
Loa Loa (eye worm) oxidoreductase 0.0064 0.0394 0.0394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.004 0.0135
Plasmodium vivax SET domain protein, putative 0.0033 0.0156 0.1106
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.004 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Plasmodium falciparum aldehyde reductase, putative 0.0019 0.005 0.0229
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0136 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Loa Loa (eye worm) MBCTL1 0.0054 0.0317 0.0317
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.2145 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0156 0.0309
Echinococcus granulosus transcription factor btf3 0.0072 0.0449 0.0887
Echinococcus granulosus expressed conserved protein 0.0094 0.0615 0.1215
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0181 0.1271 0.5925
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0062 0.0287
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0181 0.0843
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Echinococcus multilocularis lysine specific demethylase 5A 0.0094 0.0616 0.1009
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0531 0.0867
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0181 0.1271 0.5925
Schistosoma mansoni tyrosine kinase 0.0058 0.0347 0.0685
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0085 0.0102
Onchocerca volvulus 0.0017 0.004 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0181 0.0843
Brugia malayi jmjC domain containing protein 0.0025 0.0098 0.0193
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0181 0.0282
Trichomonas vaginalis heat shock protein, putative 0.004 0.0209 0.0976
Toxoplasma gondii aldose reductase, putative 0.0064 0.0394 0.2954
Schistosoma mansoni hypothetical protein 0.0066 0.0401 0.0792
Onchocerca volvulus 0.0017 0.004 0.004
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0167 0.1062
Loa Loa (eye worm) fibroinase 0.0018 0.0045 0.0045
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.009 0.0108
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0045 0.0045
Echinococcus multilocularis cysteine protease 0.0018 0.0045 0.0055
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0128 0.0253
Schistosoma mansoni potassium channel beta 0.0019 0.005 0.0098
Echinococcus multilocularis lamin dm0 0.0058 0.0342 0.0551
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0019 0.005 0.0232
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.059 0.1164
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Plasmodium vivax heat shock protein, putative 0.0177 0.1238 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0079
Entamoeba histolytica aldose reductase, putative 0.0064 0.0394 0.1835
Entamoeba histolytica heat shock protein 90, putative 0.0047 0.026 0.1212
Schistosoma mansoni lamin 0.0058 0.0342 0.0675
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0449 0.2094
Onchocerca volvulus 0.0017 0.004 0.004
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0058 0.0077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0011 0.0049
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.026 0.1152
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0228 0.1005
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0073 0.0461 0.0911
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Plasmodium vivax JmjC domain containing protein 0.0025 0.0098 0.0624
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0017 0.004 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0449 0.2094
Brugia malayi intermediate filament protein 0.0058 0.0342 0.0675
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0058 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0085 0.0378
Brugia malayi hypothetical protein 0.0017 0.004 0.0079
Onchocerca volvulus 0.0019 0.005 0.005
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0739 0.1215
Loa Loa (eye worm) RecQ helicase 0.002 0.0058 0.0058
Schistosoma mansoni DNA helicase recq5 0.002 0.0058 0.0115
Onchocerca volvulus Phospholipase A2 homolog 0.0283 0.2034 0.2034
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.005 0.0232
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0654 0.1292
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.1464 0.2891
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0449 0.2025
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Loa Loa (eye worm) hypothetical protein 0.0083 0.0531 0.0531
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0703 0.3198
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0181 0.0181
Schistosoma mansoni hypothetical protein 0.0066 0.0401 0.0792
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0064 0.0394 0.0777
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0105 0.0155
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.004 0.0209 0.0413
Onchocerca volvulus 0.0017 0.004 0.004
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0017 0.004 0.0079
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0058 0.0115
Trypanosoma brucei transcription factor BTF3, putative 0.0072 0.0449 0.2025
Echinococcus granulosus voltage gated potassium channel subunit 0.0019 0.005 0.0098
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0128 0.0739
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0141 0.0141
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0154 0.1068 0.1764
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0661 0.3003
Loa Loa (eye worm) heat shock protein 75 0.0031 0.0142 0.0142
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0017 0.004 0.0047
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0031 0.0142 0.0142
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0272 0.1207
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0022 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.028 0.1246
Leishmania major aldo-keto reductase-like protein 0.0064 0.0394 0.1769
Onchocerca volvulus 0.0017 0.004 0.004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0098 0.0193
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.004 0.0079
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0085 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0045 0.0187
Onchocerca volvulus 0.0018 0.0045 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0011 0.0049
Brugia malayi AMP-binding enzyme family protein 0.0024 0.009 0.0179
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0633 0.466 0.9202
Toxoplasma gondii heat shock protein 75, putative 0.0031 0.0142 0.0856
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0238 0.1112
Brugia malayi AMP-binding enzyme family protein 0.0024 0.009 0.0179
Trichomonas vaginalis set domain proteins, putative 0.024 0.171 0.7973
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0051 0.0185
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0105 0.0105
Onchocerca volvulus 0.0064 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0064 0.0394 0.0394
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0128 0.0128
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0405 0.0405
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0017 0.004 0.0047
Echinococcus multilocularis insulin receptor 0.013 0.0888 0.1464
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0098 0.0193
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0317 0.0626
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Echinococcus multilocularis muscleblind protein 0.0152 0.1049 0.1734
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0863 0.854
Loa Loa (eye worm) RNA binding protein 0.0064 0.0393 0.0393
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Trypanosoma brucei trypanothione reductase 0.005 0.0285 0.1269
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0031 0.0142 0.0218
Echinococcus multilocularis cysteine protease 0.0018 0.0045 0.0055
Echinococcus granulosus flap endonuclease 1 0.0026 0.0105 0.0207
Echinococcus granulosus dna polymerase kappa 0.01 0.0661 0.1305
Loa Loa (eye worm) hypothetical protein 0.0207 0.1464 0.1464
Echinococcus multilocularis 0.0017 0.0037 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Brugia malayi hypothetical protein 0.0252 0.1801 0.3556
Echinococcus multilocularis heat shock protein 90 0.0047 0.026 0.0414
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0164 0.0764
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.004 0.0135
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0058 0.0298
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0098 0.0143
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0058 0.0115
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0058 0.0298
Brugia malayi jmjC domain containing protein 0.0154 0.1068 0.2108
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0098 0.0193
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0045 0.0045
Toxoplasma gondii heat shock protein 90, putative 0.0047 0.026 0.1838
Echinococcus multilocularis aldo keto reductase 0.0064 0.0394 0.0638
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0005 0.001
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0064 0.0394 0.1835
Mycobacterium ulcerans heat shock protein 90 0.0044 0.0238 0.0424
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.2176 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0073 0.0461 0.0461
Loa Loa (eye worm) histone methyltransferase 0.003 0.0134 0.0134
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0085 0.0097
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0019 0.005 0.0229
Schistosoma mansoni tyrosine kinase 0.013 0.0888 0.1754
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0134 0.0203
Schistosoma mansoni ap endonuclease 0.0019 0.0051 0.01
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0633 0.466 0.466
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0703 0.3278
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Echinococcus multilocularis cpg binding protein 0.0095 0.0619 0.1015
Onchocerca volvulus 0.0017 0.004 0.004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0062 0.0287
Brugia malayi beta-NAC-like protein 0.0072 0.0449 0.0887
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0154 0.1068 0.2108
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0228 0.1005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0228 0.1005
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0739 0.146
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Loa Loa (eye worm) ctsf protein 0.0018 0.0045 0.0045
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0031 0.0142 0.0664
Onchocerca volvulus Serine\/threonine kinase homolog 0.0106 0.0703 0.0703
Trypanosoma brucei unspecified product 0.0093 0.0611 0.2774
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0017 0.004 0.0079
Echinococcus granulosus intermediate filament protein 0.0058 0.0342 0.0675
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.004 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.004 0.0047
Schistosoma mansoni SET domain protein 0.0036 0.0178 0.0352
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.1104 0.2275
Brugia malayi hypothetical protein 0.0017 0.004 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0085 0.0518
Onchocerca volvulus 0.0058 0.0342 0.0342
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Giardia lamblia Grp94/Hsp90 0.0044 0.0238 0.0944
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Echinococcus multilocularis dna polymerase eta 0.0099 0.0652 0.107
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0167 0.1193
Brugia malayi AMP-binding enzyme family protein 0.0024 0.009 0.0179
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Loa Loa (eye worm) heat shock protein 90 0.0047 0.026 0.026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0181 0.0786
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0703 0.3198
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0081 0.0324
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.004 0.0135
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0767 0.1557
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.059 0.0965
Toxoplasma gondii cathepsin CPL 0.0018 0.0045 0.0041
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0045 0.0088
Echinococcus multilocularis aldo keto reductase 0.0064 0.0394 0.0638
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0401 0.0792
Echinococcus multilocularis geminin 0.0166 0.1157 0.1913
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0767 0.1557
Echinococcus granulosus cpg binding protein 0.0095 0.0619 0.1223
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0064 0.0394 0.0638
Trypanosoma brucei heat shock protein 84, putative 0.0031 0.0142 0.0609
Trypanosoma brucei prostaglandin f synthase 0.0064 0.0394 0.1769
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.004 0.0079
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0019 0.005 0.0098
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.0972 0.192
Echinococcus granulosus aldehyde reductase 0.0046 0.0253 0.0501
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0011 0.0011
Brugia malayi Protein-tyrosine phosphatase 0.0017 0.004 0.0079
Brugia malayi Phospholipase A2 family protein 0.0283 0.2034 0.4016
Echinococcus granulosus heat shock protein 90 0.0047 0.026 0.0513
Loa Loa (eye worm) hypothetical protein 0.0181 0.1271 0.1271
Echinococcus multilocularis endoplasmin 0.0044 0.0238 0.0378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Mycobacterium ulcerans oxidoreductase 0.0064 0.0394 0.0756
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0118 0.0177
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Giardia lamblia PHD finger protein 15 0.0029 0.0128 0.0421
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0051 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Loa Loa (eye worm) hypothetical protein 0.002 0.0058 0.0058
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0081 0.0483
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0156 0.0241
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.1132 0.1872
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0011 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0298 0.1327
Loa Loa (eye worm) hypothetical protein 0.0029 0.0128 0.0128
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0661 0.3003
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0268 0.0268
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.004 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.034 0.1519
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0449 0.2025
Onchocerca volvulus 0.0033 0.0156 0.0156
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0181 0.1271 0.251
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0183 0.1287 0.5893
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0081 0.0324
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0156 0.0309
Loa Loa (eye worm) CXXC zinc finger family protein 0.0089 0.0581 0.0581
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.013 0.0755
Brugia malayi Protein-tyrosine phosphatase 1 0.0017 0.004 0.0079
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0214 0.0337
Schistosoma mansoni hypothetical protein 0.0083 0.0531 0.1049
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0405 0.1821
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0017 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0098 0.0098
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0167 0.033
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Leishmania major DNA polymerase kappa, putative 0.008 0.0511 0.231
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.1132 0.2236
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0051 0.0051
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0058 0.022
Schistosoma mansoni heat shock protein 0.0031 0.0142 0.0281
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0863 0.1761
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0017 0.004 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0767 0.1557
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0192 0.1349 0.2664
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.008 0.0511 0.101
Echinococcus granulosus lamin dm0 0.0058 0.0342 0.0675
Schistosoma mansoni endoplasmin 0.0047 0.026 0.0513
Onchocerca volvulus 0.0015 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0048 0.0268 0.0268
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0534 0.1054
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0011 0.0049
Schistosoma mansoni cpg binding protein 0.0095 0.0619 0.1223
Echinococcus multilocularis musashi 0.0058 0.0342 0.0551
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.034 0.1519
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0045 0.0045
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0098 0.0193
Onchocerca volvulus 0.0017 0.004 0.004
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0058 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2145 1
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.0209 0.0918
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0128 0.0194
Trypanosoma brucei protein tyrosine phosphatase 1 0.0017 0.004 0.0137
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0192 0.1351 0.2667
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0051 0.0236
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0051 0.0052
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0268 0.0528
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0045 0.0187
Loa Loa (eye worm) hypothetical protein 0.0142 0.0972 0.0972
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0268 0.0427
Leishmania major prostaglandin f synthase, putative 0.0064 0.0394 0.1769
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.004 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0017 0.004 0.0079
Onchocerca volvulus 0.0017 0.004 0.004
Echinococcus multilocularis heat shock protein 90 0.004 0.0209 0.033
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0079
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0098 0.0143
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0192 0.1349 0.2234
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.004 0.0135
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0285 0.2167
Entamoeba histolytica hypothetical protein 0.0111 0.0739 0.3447
Schistosoma mansoni DNA polymerase eta 0.0099 0.0652 0.1288
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0181 0.0843
Loa Loa (eye worm) cysteine protease 0.0018 0.0045 0.0045
Schistosoma mansoni heat shock protein 0.0047 0.026 0.0513
Onchocerca volvulus 0.0017 0.004 0.004
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.009 0.0113
Entamoeba histolytica heat shock protein 90, putative 0.0047 0.026 0.1212
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.026 0.1152
Leishmania major DNA polymerase eta, putative 0.0099 0.0652 0.2964
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0633 0.466 0.7768
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0531 0.0531
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0047
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0081 0.0483
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0017 0.004 0.004
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.0641 0.4725 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0405 0.1888
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0687 0.5064 1
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0633 0.466 0.466
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0661 0.3003
Brugia malayi mbt repeat family protein 0.0048 0.0268 0.0528
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0342 0.0675
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.009 0.0108
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0085 0.037
Trypanosoma brucei glucosidase, putative 0.0036 0.0181 0.0786
Trypanosoma brucei aldo/keto reductase, putative 0.0019 0.005 0.0181
Onchocerca volvulus 0.0094 0.0617 0.0617
Schistosoma mansoni endoplasmin 0.0047 0.026 0.0513
Onchocerca volvulus 4.1 G protein, putative homolog 0.0017 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis aldo keto reductase 0.0064 0.0394 0.0638
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0106 0.0703 0.1155
Loa Loa (eye worm) oxidoreductase 0.0064 0.0394 0.0394
Mycobacterium tuberculosis Probable oxidoreductase 0.0064 0.0394 0.076
Loa Loa (eye worm) hypothetical protein 0.0088 0.0571 0.0571
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0134 0.0264
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.026 0.1152
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.0355 0.0573
Trypanosoma brucei unspecified product 0.0051 0.029 0.129
Entamoeba histolytica hypothetical protein 0.0023 0.0085 0.0396
Brugia malayi heat shock protein 90 0.0047 0.026 0.0513
Loa Loa (eye worm) hypothetical protein 0.0283 0.2034 0.2034
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0767 0.7535
Onchocerca volvulus 0.0018 0.0045 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.059 0.1164
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.0355 0.0573
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0081 0.0324
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.004 0.0047
Trypanosoma brucei Heat shock protein 83, putative 0.0047 0.026 0.1152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Plasmodium vivax vivapain-2 0.0018 0.0045 0.0187
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0045 0.0208
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0098 0.0403
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0393 0.0776
Onchocerca volvulus Phospholipase A2 homolog 0.1344 1 1
Brugia malayi NADH-dependent xylose reductase 0.0019 0.005 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0511 0.231
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0017 0.004 0.0137
Entamoeba histolytica aldose reductase, putative 0.0064 0.0394 0.1835
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Schistosoma mansoni flap endonuclease-1 0.0024 0.0086 0.017
Schistosoma mansoni heat shock protein 0.0047 0.026 0.0513
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0304 0.0304
Mycobacterium ulcerans hypothetical protein 0.0159 0.1104 0.2271
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0181 0.0357
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0106 0.0703 0.0703
Brugia malayi Peptidase family C54 containing protein 0.0181 0.1271 0.251
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.013 0.0888 0.1464
Schistosoma mansoni terminal deoxycytidyl transferase 0.0073 0.0461 0.0911
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0011 0.0049
Brugia malayi TAR-binding protein 0.0064 0.0393 0.0776
Brugia malayi Thioredoxin reductase 0.005 0.0285 0.0564
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0011 0.0049
Schistosoma mansoni hypothetical protein 0.0083 0.0531 0.1049
Leishmania major cathepsin L-like protease 0.0069 0.0425 0.1912
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0081 0.0342
Schistosoma mansoni hypothetical protein 0.0041 0.022 0.0435
Leishmania major DNA polymerase eta, putative 0.0048 0.0272 0.1207
Loa Loa (eye worm) hypothetical protein 0.0054 0.0317 0.0317
Trichomonas vaginalis aldo-keto reductase, putative 0.0064 0.0394 0.1835
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0342 0.0342
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0088
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0534 0.1054
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0045 0.0055
Brugia malayi Protein kinase domain containing protein 0.0072 0.0451 0.0891
Plasmodium falciparum thioredoxin reductase 0.005 0.0285 0.2167
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0098 0.0143
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0687 0.5064 0.5064
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0017 0.004 0.0047
Trypanosoma brucei DNA polymerase eta, putative 0.0099 0.0652 0.2964
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0181 0.0843
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0019 0.005 0.0083
Schistosoma mansoni alpha-glucosidase 0.014 0.0962 0.19
Brugia malayi glutathione reductase 0.005 0.0285 0.0564
Brugia malayi Bromodomain containing protein 0.0029 0.0128 0.0253
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.004 0.004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0405 0.1821
Echinococcus granulosus insulin growth factor 1 receptor beta 0.013 0.0888 0.1754
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0064 0.0394 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0232 0.1081
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.2145 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0062 0.0287
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1287 0.2541
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0181 0.1271 0.5925
Brugia malayi PHD-finger family protein 0.0015 0.0019 0.0038
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0167 0.0259
Trypanosoma brucei polo-like protein kinase 0.0106 0.0703 0.3198
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0085 0.0097
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.059 0.059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0208
Brugia malayi PHD-finger family protein 0.0029 0.0128 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0318 0.1482
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.009 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0425 0.1912
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0405 0.1821
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0045 0.0208
Loa Loa (eye worm) hypothetical protein 0.0066 0.0401 0.0401
Brugia malayi hypothetical protein 0.0111 0.0739 0.146
Trypanosoma brucei heat shock protein, putative 0.0047 0.026 0.1152
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0633 0.466 0.466
Echinococcus granulosus muscleblind protein 0.0152 0.1049 0.2072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0208
Schistosoma mansoni patched 1 0.0043 0.0232 0.0458
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0128 0.0253
Entamoeba histolytica transcription factor BTF3, putative 0.0072 0.0449 0.2094
Echinococcus granulosus heat shock protein 90 0.004 0.0209 0.0413
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Brugia malayi Augmenter of liver regeneration 0.0034 0.0167 0.033
Onchocerca volvulus 0.0017 0.004 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.009 0.0108
Loa Loa (eye worm) hypothetical protein 0.0057 0.0334 0.0334
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0393 0.0776
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0017 0.004 0.0137
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.009 0.0113
Entamoeba histolytica hypothetical protein 0.0111 0.0739 0.3447
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.2176 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.1002 0.2058
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0062 0.0287
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.004 0.0047
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0064 0.0394 0.0777
Echinococcus multilocularis dual specificity 0.0183 0.1287 0.213
Echinococcus multilocularis dna polymerase kappa 0.01 0.0661 0.1084
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0393 0.0776
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0531 0.1049
Brugia malayi hypothetical protein 0.0017 0.004 0.0079
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.005 0.0232
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0181 0.0357
Leishmania major heat shock protein 83-1 0.0047 0.026 0.1152
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0051 0.0236
Brugia malayi Pre-SET motif family protein 0.0211 0.1495 0.2951
Echinococcus multilocularis protein patched 0.0043 0.0232 0.0367
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0181 0.1271 0.251
Onchocerca volvulus 0.0083 0.0534 0.0534
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.059 0.0965
Toxoplasma gondii histone lysine methyltransferase SET1 0.0172 0.1199 0.9671
Schistosoma mansoni serine/threonine protein kinase 0.0633 0.466 0.9202
Brugia malayi mbt repeat family protein 0.0048 0.0268 0.0528
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0863 0.1761
Schistosoma mansoni hypothetical protein 0.0401 0.2921 0.5768
Plasmodium vivax vivapain-2 0.0018 0.0045 0.0187
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Plasmodium vivax endoplasmin, putative 0.0047 0.026 0.1958
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0098 0.0624
Plasmodium vivax aldehyde reductase, putative 0.0019 0.005 0.0229
Toxoplasma gondii aldo-keto reductase 0.0019 0.005 0.0083

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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