Detailed information for compound 1159748

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 256.386 | Formula: C17H24N2
  • H donors: 0 H acceptors: 0 LogP: 3.59 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCC(CC1)CCc1cn(c2c1cccc2)C
  • InChi: 1S/C17H24N2/c1-18-11-9-14(10-12-18)7-8-15-13-19(2)17-6-4-3-5-16(15)17/h3-6,13-14H,7-12H2,1-2H3
  • InChiKey: UNRQUBJIEJFQTD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni survival motor neuron protein 0.0054 0.131 0.131
Leishmania major hypothetical protein, conserved 0.0038 0.0709 0.2301
Loa Loa (eye worm) hypothetical protein 0.0099 0.3075 0.3075
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0473 0.0473
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.0597
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0681 0.0597
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Loa Loa (eye worm) calpain 0.0037 0.0681 0.0681
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0092 0.2785 0.2785
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.2195
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0517 0.0517
Onchocerca volvulus 0.0062 0.1625 0.1721
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.2195
Brugia malayi Thioredoxin reductase 0.0053 0.1269 0.1269
Loa Loa (eye worm) hypothetical protein 0.0023 0.0125 0.0125
Brugia malayi calpain family protein 1 0.0099 0.3075 0.3075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0517 0.0517
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.1269 0.2738
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0037 0.0681 0.0597
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0274 0.0274
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.82 0.82
Brugia malayi Pre-SET motif family protein 0.0231 0.82 0.82
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0036 0.061 0.061
Echinococcus multilocularis hypothetical protein 0.0037 0.0681 0.0681
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.3831 0.3831
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Trypanosoma brucei cysteine peptidase C (CPC) 0.0092 0.2785 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0681 0.0597
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.3831 0.3831
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0036 0.061 0.1457
Brugia malayi Glutamate receptor 1 precursor 0.0024 0.0173 0.0173
Plasmodium vivax SET domain protein, putative 0.0033 0.0517 0.4079
Plasmodium falciparum thioredoxin reductase 0.0053 0.1269 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.2814 0.2814
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Brugia malayi Augmenter of liver regeneration 0.0038 0.0709 0.0709
Trichomonas vaginalis set domain proteins, putative 0.0263 0.9439 1
Schistosoma mansoni lipoxygenase 0.0119 0.3831 0.3831
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.1269 0.1269
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0133 0.4398 1
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0473 0.0473
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0517 0.1095
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0517 0.0517
Echinococcus multilocularis survival motor neuron protein 1 0.0263 0.9422 0.9422
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0352 0.0352
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0681 0.0597
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.061 0.1931
Loa Loa (eye worm) hypothetical protein 0.0073 0.2061 0.2061
Trypanosoma cruzi Aminopeptidase M1, putative 0.0036 0.061 0.0525
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0517 0.0517
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.1269 0.1269
Onchocerca volvulus 0.0121 0.3914 0.4147
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0274 0.0274
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0104 0.3249 0.3249
Plasmodium vivax calpain, putative 0.0037 0.0681 0.5367
Schistosoma mansoni calpain (C02 family) 0.0037 0.0681 0.0681
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0709 0.1849
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.2814 0.2814
Mycobacterium tuberculosis Putative ferredoxin reductase 0.012 0.3879 0.8796
Loa Loa (eye worm) aminopeptidase N 0.0036 0.061 0.061
Echinococcus granulosus glutamate NMDA receptor subunit 0.0024 0.0173 0.0173
Mycobacterium tuberculosis Probable oxidoreductase 0.0133 0.4398 1
Echinococcus multilocularis cathepsin b 0.0278 1 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0517 0.0517
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.061 0.0366
Loa Loa (eye worm) hypothetical protein 0.0055 0.1379 0.1379
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.1202 0.1202
Echinococcus multilocularis calpain A 0.0104 0.3249 0.3249
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0239 0.2876
Brugia malayi calpain 7 0.0037 0.0681 0.0681
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0709 0.1849
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.1202 0.1202
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0092 0.2785 0.272
Plasmodium vivax glutathione reductase, putative 0.0053 0.1269 1
Onchocerca volvulus 0.0092 0.2814 0.2981
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.1269 1
Echinococcus granulosus aminopeptidase N 0.0121 0.3914 0.3914
Schistosoma mansoni calpain C (C02 family) 0.0037 0.0681 0.0681
Echinococcus granulosus calpain A 0.0037 0.0681 0.0681
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.1202 0.1202
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0239 0.5
Giardia lamblia Cathepsin B precursor 0.0092 0.2785 1
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0038 0.0709 0.0709
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0173 0.0173
Onchocerca volvulus 0.0036 0.061 0.0646
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.07 0.07
Brugia malayi calpain family protein 1 0.0099 0.3075 0.3075
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.1269 0.119
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0023 0.0125 0.2383
Loa Loa (eye worm) hypothetical protein 0.0149 0.5015 0.5015
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0036 0.061 0.061
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0709 0.5591
Brugia malayi Pre-SET motif family protein 0.0033 0.0517 0.0517
Loa Loa (eye worm) cathepsin B 0.0092 0.2785 0.2785
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0352 0.0352
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0681 0.0597
Echinococcus multilocularis calpain family protein 1, d 0.0073 0.2061 0.2061
Entamoeba histolytica aminopeptidase, putative 0.0036 0.061 1
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0274 0.2161
Echinococcus granulosus calpain 0.0037 0.0681 0.0681
Giardia lamblia Cathepsin B precursor 0.0092 0.2785 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.1202 0.1202
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0133 0.4398 1
Echinococcus granulosus allatostatin A receptor 0.0149 0.5015 0.5015
Loa Loa (eye worm) hypothetical protein 0.0108 0.343 0.343
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0274 0.0274
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0036 0.061 0.061
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0104 0.3249 0.3249
Onchocerca volvulus 0.0033 0.0517 0.0548
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0274 0.0187
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0274 0.0274
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.2814 0.2814
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0023 0.0125 0.0685
Loa Loa (eye worm) glutamate receptor 2 0.0024 0.0173 0.0173
Echinococcus granulosus cathepsin b 0.0278 1 1
Echinococcus multilocularis calpain 5 0.0037 0.0681 0.0681
Leishmania major kinesin, putative 0.0026 0.0245 0.0579
Schistosoma mansoni hypothetical protein 0.0054 0.131 0.131
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0038 0.0709 0.0709
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0274 0.0139
Trypanosoma cruzi kinesin, putative 0.0026 0.0245 0.0157
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0278 1 1
Brugia malayi Peptidase family M1 containing protein 0.0036 0.061 0.061
Trypanosoma cruzi kinesin, putative 0.0026 0.0245 0.0157
Entamoeba histolytica protein kinase, putative 0.0026 0.0245 0.0169
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.1379 0.1379
Schistosoma mansoni Mername-AA248 (C02 family) 0.0037 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0085 0.2536 0.2536
Trypanosoma brucei trypanothione reductase 0.0053 0.1269 0.4046
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0274 0.0274
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0239 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.2814 0.2814
Brugia malayi hypothetical protein 0.0263 0.9422 0.9422
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0239 0.0347
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.012 0.3879 0.8796
Loa Loa (eye worm) calpain family protein 1 0.0099 0.3075 0.3075
Trypanosoma brucei calpain-like protein, putative 0.0037 0.0681 0.1737
Loa Loa (eye worm) hypothetical protein 0.0092 0.2814 0.2814
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0089 0.0702
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.047 0.047
Echinococcus granulosus cathepsin b 0.0278 1 1
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0024 0.0173 0.0173
Echinococcus multilocularis aminopeptidase N 0.0121 0.3914 0.3914
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0173 0.0173
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0023 0.0125 0.0125
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0274 0.0274
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0278 1 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0517 0.0517
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0681 0.0597
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0133 0.4398 1
Giardia lamblia Cathepsin B precursor 0.0092 0.2785 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0239 0.1882
Echinococcus multilocularis allatostatin A receptor 0.0149 0.5015 0.5015
Mycobacterium tuberculosis Probable reductase 0.012 0.3879 0.8796
Loa Loa (eye worm) hypothetical protein 0.0023 0.0125 0.0125
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0239 0.0555
Toxoplasma gondii thioredoxin reductase 0.0053 0.1269 0.4046
Onchocerca volvulus 0.0149 0.5015 0.5313
Brugia malayi glutathione reductase 0.0053 0.1269 0.1269
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0278 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.1202 0.1202
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0104 0.3249 0.3249
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.1379 0.1379
Loa Loa (eye worm) calpain family protein 1 0.0073 0.2061 0.2061
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0352 0.0352
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0173 0.0173
Trypanosoma brucei Aminopeptidase M1, putative 0.0036 0.061 0.1457
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.061 0.1931
Onchocerca volvulus 0.0263 0.9439 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.1737
Brugia malayi hypothetical protein 0.0036 0.061 0.061
Trypanosoma brucei antigen, putative 0.0037 0.0681 0.1737
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0709 0.1849
Echinococcus granulosus glutamate receptor 2 0.0029 0.0352 0.0352
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0352 0.0352
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0473 0.0473
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.012 0.3879 0.8753
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0239 0.2876
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0274 0.0139
Trypanosoma brucei calpain-like protein, putative 0.0037 0.0681 0.1737
Schistosoma mansoni glutamate receptor NMDA 0.0024 0.0173 0.0173
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0274 0.2161
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0036 0.061 0.0525
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0352 0.0352
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0125 0.0083
Echinococcus granulosus glutamate receptor 2 0.002 0.0003 0.0003
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0709 0.0626
Loa Loa (eye worm) hypothetical protein 0.0062 0.1625 0.1625
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0278 1 1
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0352 0.0352
Schistosoma mansoni glutamate receptor AMPA 0.0024 0.0173 0.0173
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Onchocerca volvulus 0.0054 0.131 0.1387
Trypanosoma brucei kinesin, putative 0.0026 0.0245 0.0025
Schistosoma mansoni ATP-binding cassette transporter 0.0024 0.0173 0.0173
Echinococcus multilocularis glutamate receptor 2 0.0024 0.0173 0.0173
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.131 0.131
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0239 1
Schistosoma mansoni lipoxygenase 0.0083 0.2447 0.2447
Brugia malayi calpain 5 0.0026 0.0245 0.0245
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.012 0.3879 0.8796
Trypanosoma brucei calpain-like protein, putative 0.0037 0.0681 0.1737
Loa Loa (eye worm) hepatopoietin HPO2 0.0038 0.0709 0.0709
Schistosoma mansoni calpain-7 (C02 family) 0.0037 0.0681 0.0681
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0278 1 1
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.2195
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0099 0.3075 0.3075
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0352 0.0352
Loa Loa (eye worm) glutamate receptor 1 0.0024 0.0173 0.0173
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0517 0.0517
Brugia malayi Peptidase family M1 containing protein 0.0121 0.3914 0.3914
Loa Loa (eye worm) peptidase family M1 containing protein 0.0098 0.302 0.302
Loa Loa (eye worm) glutathione reductase 0.0053 0.1269 0.1269
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0709 0.5591
Loa Loa (eye worm) hypothetical protein 0.0038 0.07 0.07
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.061 0.061
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0027 0.0274 0.0956
Trypanosoma cruzi aminopeptidase, putative 0.0036 0.061 0.0525
Echinococcus multilocularis calpain 7 (C02 family) 0.0037 0.0681 0.0681
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.0597
Leishmania major trypanothione reductase 0.0053 0.1269 0.4376
Schistosoma mansoni hypothetical protein 0.0038 0.07 0.07
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0023 0.0125 0.0036
Loa Loa (eye worm) calpain 5 0.0026 0.0245 0.0245
Brugia malayi Glutamate receptor 2 precursor 0.0024 0.0173 0.0173
Trypanosoma brucei calpain-like protein, putative 0.0037 0.0681 0.1737
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0037 0.0681 0.1737
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.1202 0.1202
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0092 0.2785 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.061 0.0366
Echinococcus granulosus calpain A 0.0104 0.3249 0.3249
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0239 0.1882
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.0597
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.012 0.3879 0.8796
Toxoplasma gondii cathepsin B 0.0092 0.2785 1
Mycobacterium ulcerans aminopeptidase N PepN 0.0036 0.061 1
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0023 0.0125 0.2383
Loa Loa (eye worm) hypothetical protein 0.0263 0.9422 0.9422
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0029 0.0352 0.0352
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0104 0.3249 0.3249
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.1202 0.1202
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0709 0.0626
Echinococcus multilocularis glutamate receptor 2 0.002 0.0003 0.0003
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0274 0.0274
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.1269 0.1269
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0278 1 1
Echinococcus multilocularis cathepsin b 0.0278 1 1
Echinococcus granulosus calpain 5 0.0037 0.0681 0.0681
Echinococcus granulosus survival motor neuron protein 1 0.0263 0.9422 0.9422
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0029 0.0352 0.0352
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.1202 0.1202
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0517 0.0517
Trypanosoma brucei Aminopeptidase M1, putative 0.0036 0.061 0.1457
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0092 0.2785 0.2739
Loa Loa (eye worm) hypothetical protein 0.0088 0.2639 0.2639
Echinococcus multilocularis calpain 0.0037 0.0681 0.0681
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0023 0.0125 0.0125
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0274 0.0274
Schistosoma mansoni calpain-7 (C02 family) 0.0037 0.0681 0.0681
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.1379 0.1379
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0149 0.5015 0.5015
Plasmodium falciparum glutathione reductase 0.0053 0.1269 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0681 0.0597
Echinococcus granulosus calpain 7 C02 family 0.0037 0.0681 0.0681
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0274 0.0687
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0709 0.0626
Mycobacterium tuberculosis Probable dehydrogenase 0.012 0.3879 0.8796
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.1202 0.1202
Schistosoma mansoni glutamate receptor AMPA 0.0024 0.0173 0.0173
Entamoeba histolytica calpain large subunit domain III containing protein 0.0026 0.0245 0.0169

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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