Detailed information for compound 1175677

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 805.016 | Formula: C47H60N6O6
  • H donors: 4 H acceptors: 6 LogP: 7.31 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)N[C@@H](C(C)(C)C)C(=O)N[C@@H](C[C@@H]([C@@H](NC(=O)[C@H](C(C)(C)C)N1CCN(C1=O)Cc1ccccc1)Cc1ccccc1)O)Cc1ccc(cc1)c1ccccn1
  • InChi: 1S/C47H60N6O6/c1-46(2,3)40(51-44(57)59-7)42(55)49-36(28-33-21-23-35(24-22-33)37-20-14-15-25-48-37)30-39(54)38(29-32-16-10-8-11-17-32)50-43(56)41(47(4,5)6)53-27-26-52(45(53)58)31-34-18-12-9-13-19-34/h8-25,36,38-41,54H,26-31H2,1-7H3,(H,49,55)(H,50,56)(H,51,57)/t36-,38+,39+,40-,41-/m1/s1
  • InChiKey: KMAMPFGXPHTYPQ-YPINIOOUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum serine repeat antigen 3 0.044 0.0823 0.2306
Plasmodium vivax unspecified product 0.044 0.0823 0.2306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Trypanosoma cruzi cysteine peptidase, putative 0.0569 0.1076 0.1257
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.005
Leishmania major cytochrome p450-like protein 0.0022 0.0004 0.0012
Leishmania major fatty acid elongase, putative 0.002 0.0001 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0009 0.0025
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0004 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.0114 0.0114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4391 0.8563 0.8563
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0043 0.1405
Toxoplasma gondii GNS1/SUR4 family protein 0.002 0.0001 0.0003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.0823 0.0823
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.044 0.0823 0.2306
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Plasmodium falciparum serine repeat antigen 4 0.044 0.0823 0.2306
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0009 0.0025
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0052 0.0063 0.0074
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.031
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0067 0.0078
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0043 0.0109
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.003 0.0021 0.006
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0184 0.0323 0.0323
Schistosoma mansoni P2X receptor subunit 0.0044 0.0049 0.0049
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0046 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0026 0.003
Entamoeba histolytica cysteine protease, putative 0.1842 0.3571 1
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0175 0.0305 0.0356
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0004 0.0004
Leishmania major acetyl-CoA synthetase, putative 0.0046 0.0053 0.0149
Brugia malayi AMP-binding enzyme family protein 0.0158 0.0272 0.0318
Echinococcus granulosus chromobox protein 1 0.0074 0.0107 0.0107
Onchocerca volvulus 0.0152 0.0259 0.0652
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0053 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Schistosoma mansoni biogenic amine receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.0032 0.0026 0.0065
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0056 0.0071 0.0083
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0053 0.0062
Brugia malayi Peptidase family M13 containing protein 0.0056 0.0071 0.0083
Brugia malayi prolyl oligopeptidase family protein 0.0175 0.0305 0.0356
Loa Loa (eye worm) prolyl oligopeptidase 0.0175 0.0305 0.0356
Echinococcus multilocularis cathepsin L cysteine protease 0.1842 0.3571 0.3571
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0205 0.0363 0.0424
Onchocerca volvulus 0.1842 0.3571 0.8991
Giardia lamblia Dipeptidyl-peptidase I precursor 0.044 0.0823 0.2559
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.0114 0.0114
Toxoplasma gondii preprocathepsin c precursor, putative 0.044 0.0823 0.2306
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.0114 0.0114
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0184 0.0323 0.0323
Schistosoma mansoni cytochrome P450 0.0022 0.0004 0.0004
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0009 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0121
Giardia lamblia Cathepsin L-like protease 0.044 0.0823 0.2559
Brugia malayi Pre-SET motif family protein 0.1286 0.2481 0.2897
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0175 0.0305 0.0853
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Echinococcus granulosus sphingosine kinase 1 0.0163 0.0281 0.0281
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0025 0.0025
Leishmania major hypothetical protein, conserved 0.0155 0.0265 0.0742
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.0078 0.0114 0.0288
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0004 0.0144
Trichomonas vaginalis D-aminoacylase, putative 0.0155 0.0265 0.0742
Loa Loa (eye worm) hypothetical protein 0.0158 0.0272 0.0318
Entamoeba histolytica hypothetical protein 0.0112 0.0182 0.0509
Echinococcus multilocularis neuropeptide receptor A26 0.0529 0.0999 0.0999
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0046 0.0053 0.0149
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0214 0.0382 0.0382
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0118 0.0194 0.1021
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0138 0.0232 0.0651
Entamoeba histolytica papain family cysteine protease domain containing protein 0.044 0.0823 0.2306
Schistosoma mansoni cathepsin S (C01 family) 0.044 0.0823 0.0823
Leishmania major mitochondrial DNA polymerase beta 0.0205 0.0363 0.1018
Brugia malayi Muscleblind-like protein 0.0447 0.0838 0.0979
Schistosoma mansoni hypothetical protein 0.0032 0.0025 0.0025
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0046 0.0053 0.1745
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.0114 0.0134
Brugia malayi Cytochrome P450 family protein 0.0068 0.0095 0.0111
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0031 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.044 0.0823 0.0961
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0078 0.0114 0.0134
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0026 0.0031
Echinococcus multilocularis sphingosine kinase 1 0.0163 0.0281 0.0281
Echinococcus granulosus 7TM GPCR rhodopsin 0.0078 0.0114 0.0114
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0059 0.0077 0.0077
Brugia malayi Papain family cysteine protease containing protein 0.044 0.0823 0.0961
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0004 0.0144
Loa Loa (eye worm) hypothetical protein 0.0175 0.0305 0.0356
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.0823 0.0823
Schistosoma mansoni microtubule-associated protein tau 0.5124 1 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Onchocerca volvulus 0.0155 0.0265 0.0667
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1842 0.3571 1
Plasmodium vivax aspartyl protease, putative 0.003 0.0021 0.006
Schistosoma mansoni histamine h1 receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.1274 0.2457 0.2869
Entamoeba histolytica cysteine proteinase, putative 0.1008 0.1937 0.5425
Echinococcus granulosus lamin 0.0054 0.0067 0.0067
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0004 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Plasmodium vivax aspartyl proteinase, putative 0.0128 0.0213 0.0596
Echinococcus multilocularis serotonin receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0013 0.0013
Echinococcus granulosus eukaryotic initiation factor 4A 0.0214 0.0382 0.0382
Onchocerca volvulus 0.0216 0.0385 0.0968
Mycobacterium leprae probable zinc metalloprotease 0.0056 0.0071 0.2215
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0052
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0162 0.0189
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0175 0.0305 0.0853
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0046 0.0053 0.028
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.0114 0.0114
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0078 0.0114 0.0114
Leishmania major hypothetical protein, conserved 0.0024 0.0009 0.0025
Echinococcus multilocularis cysteine protease 0.1842 0.3571 0.3571
Plasmodium falciparum cysteine proteinase falcipain 3 0.1842 0.3571 1
Brugia malayi G protein-coupled receptor 0.0078 0.0114 0.0134
Brugia malayi cathepsin Z-like cysteine proteinase 0.044 0.0823 0.0961
Echinococcus multilocularis acylamino acid releasing enzyme 0.0175 0.0305 0.0305
Brugia malayi Fatty acid elongation protein 3 0.002 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.044 0.0823 0.2306
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.031
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0175 0.0305 0.0853
Leishmania major oligopeptidase b 0.0175 0.0305 0.0853
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0128 0.0213 0.0249
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4391 0.8563 0.8563
Mycobacterium ulcerans lipase LipD 0.0155 0.0265 0.8701
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0004 0.0144
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0029 0.0019 0.0052
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0051 0.0062 0.0173
Entamoeba histolytica cysteine protease, putative 0.044 0.0823 0.2306
Schistosoma mansoni cathepsin C 0.044 0.0823 0.0823
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0214 0.0382 0.1068
Schistosoma mansoni cathepsin D (A01 family) 0.0378 0.0702 0.0702
Loa Loa (eye worm) hypothetical protein 0.0569 0.1076 0.1257
Entamoeba histolytica acyl-CoA synthetase, putative 0.0158 0.0272 0.0762
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.044 0.0823 0.2306
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.0114 0.0134
Brugia malayi Papain family cysteine protease containing protein 0.044 0.0823 0.0961
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0184 0.0323 0.0323
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0158 0.0272 0.1434
Plasmodium falciparum serine repeat antigen 7 0.044 0.0823 0.2306
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0205 0.0363 0.0424
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0155 0.0265 0.1397
Entamoeba histolytica acyl-coA synthetase, putative 0.0158 0.0272 0.0762
Brugia malayi eukaryotic initiation factor 4A 0.0214 0.0382 0.0446
Schistosoma mansoni P2X receptor subunit 0.0044 0.0049 0.0049
Giardia lamblia Cysteine protease 0.044 0.0823 0.2559
Schistosoma mansoni hypothetical protein 0.0112 0.0182 0.0182
Leishmania major fatty acid elongase, putative 0.002 0.0001 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0031 0.0023 0.0023
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1842 0.3571 0.417
Leishmania major cytochrome p450-like protein 0.0022 0.0004 0.0012
Loa Loa (eye worm) beta-lactamase 0.0155 0.0265 0.031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0051
Echinococcus granulosus voltage gated potassium channel 0.002 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0004 0.0144
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0052
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0175 0.0305 0.0853
Onchocerca volvulus Cathepsin L homolog 0.1842 0.3571 0.8991
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0155 0.0265 0.1397
Brugia malayi AKH receptor 0.0078 0.0114 0.0134
Toxoplasma gondii prolyl endopeptidase 0.0175 0.0305 0.0853
Brugia malayi aspartic protease BmAsp-1, identical 0.003 0.0021 0.0025
Brugia malayi neuropeptide F receptor 0.0078 0.0114 0.0134
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0059 0.0077 0.009
Giardia lamblia Cathepsin L precursor 0.044 0.0823 0.2559
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0004 0.0023
Schistosoma mansoni intermediate filament proteins 0.0054 0.0067 0.0067
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0162 0.0189
Brugia malayi Tachykinin-like peptides receptor 99D 0.0078 0.0114 0.0134
Giardia lamblia Cathepsin B precursor 0.1662 0.3217 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0988 0.1898 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.044 0.0823 0.0823
Echinococcus multilocularis prolyl endopeptidase 0.0175 0.0305 0.0305
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0028 0.0017 0.0017
Trypanosoma brucei cysteine peptidase C (CPC) 0.1662 0.3217 0.9009
Echinococcus granulosus g protein coupled receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.044 0.0823 0.2073
Brugia malayi cathepsin Z-like cysteine proteinase 0.044 0.0823 0.0961
Onchocerca volvulus 0.0046 0.0053 0.0134
Echinococcus granulosus cathepsin l cysteine peptidase 0.1842 0.3571 0.3571
Onchocerca volvulus 0.0046 0.0053 0.0134
Loa Loa (eye worm) peptidase family M13 containing protein 0.0041 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0118 0.0194 0.0226
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0046 0.0053 0.0149
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0004 0.0144
Brugia malayi cytochrome P450 0.0022 0.0004 0.0005
Brugia malayi MH2 domain containing protein 0.0236 0.0425 0.0496
Echinococcus granulosus muscleblind protein 0.0447 0.0838 0.0838
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Onchocerca volvulus 0.1842 0.3571 0.8991
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0053 0.0062
Echinococcus multilocularis serotonin receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.1842 0.3571 0.8991
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.044 0.0823 0.2306
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1662 0.3217 0.9009
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0173 0.0914
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0114 0.0114
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.044 0.0823 0.2306
Trypanosoma cruzi cruzipain precursor, putative 0.1842 0.3571 0.417
Schistosoma mansoni hypothetical protein 0.0078 0.0114 0.0114
Onchocerca volvulus 0.0078 0.0114 0.0288
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0078 0.0114 0.0134
Giardia lamblia Hypothetical protein 0.044 0.0823 0.2559
Onchocerca volvulus Cathepsin L homolog 0.1842 0.3571 0.8991
Schistosoma mansoni hypothetical protein 0.0032 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1008 0.1937 0.1937
Brugia malayi hypothetical protein 0.003 0.0021 0.0025
Onchocerca volvulus Prolyl endopeptidase homolog 0.0175 0.0305 0.0767
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0009 0.001
Echinococcus granulosus beta LACTamase domain containing family member 0.0155 0.0265 0.0265
Plasmodium vivax plasmepsin V, putative 0.003 0.0021 0.006
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1008 0.1937 0.1937
Loa Loa (eye worm) papain family cysteine protease containing protein 0.044 0.0823 0.0961
Brugia malayi Cathepsin L-like precursor 0.1274 0.2457 0.2869
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0019 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.005
Echinococcus granulosus hypothetical protein 0.0078 0.0114 0.0114
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0031 0.0023 0.0027
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0046 0.0053 0.1624
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Loa Loa (eye worm) TYRA-2 protein 0.0078 0.0114 0.0134
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0078 0.0114 0.0114
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.044 0.0823 0.2306
Echinococcus granulosus neuropeptide receptor 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0004 0.0023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0112 0.0181 0.0955
Echinococcus multilocularis cathepsin b 0.4391 0.8563 0.8563
Brugia malayi beta-lactamase 0.0155 0.0265 0.031
Loa Loa (eye worm) hypothetical protein 0.0158 0.0272 0.0318
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0078 0.0114 0.0134
Trypanosoma cruzi cruzipain precursor, putative 0.0569 0.1076 0.1257
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0025 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0031 0.0023 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0158 0.0272 0.8934
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0158 0.0272 0.0762
Schistosoma mansoni cathepsin s 0.0569 0.1076 0.1076
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0028 0.0017 0.0017
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0214 0.0382 0.1068
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0214 0.0382 0.1068
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0041 0.0043 0.012
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Onchocerca volvulus 0.0078 0.0114 0.0288
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.2047 0.3971 0.3971
Mycobacterium ulcerans acyl-CoA synthetase 0.0158 0.0272 0.8934
Plasmodium falciparum long chain fatty acid elongation enzyme, putative 0.002 0.0001 0.0003
Plasmodium vivax serine-repeat antigen (SERA), putative 0.044 0.0823 0.2306
Trypanosoma cruzi cysteine proteinase, putative 0.1008 0.1937 0.2262
Schistosoma mansoni cellular tumor antigen P53 0.0216 0.0385 0.0385
Entamoeba histolytica cysteine protease, putative 0.044 0.0823 0.2306
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0009 0.001
Echinococcus multilocularis chromobox protein 1 0.0074 0.0107 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0004 0.0023
Mycobacterium tuberculosis Probable oxidoreductase 0.0166 0.0288 0.1517
Echinococcus granulosus g-protein coupled receptor 0.0078 0.0114 0.0114
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0158 0.0272 0.8934
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.007 0.0099 0.0115
Echinococcus multilocularis cysteine protease 0.1842 0.3571 0.3571
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.044 0.0823 0.0823
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0046 0.0053 0.028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.044 0.0823 0.2306
Echinococcus granulosus p2X purinoceptor 4 0.0044 0.0049 0.0049
Giardia lamblia Cathepsin B precursor 0.044 0.0823 0.2559
Echinococcus granulosus histone lysine methyltransferase setb 0.0184 0.0323 0.0323
Trypanosoma cruzi cysteine protease, putative 0.1008 0.1937 0.2262
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0128 0.0213 0.0213
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0026 0.0073
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0078 0.0114 0.0114
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0819 0.1566 0.4386
Mycobacterium leprae Probable lipase LipE 0.0155 0.0265 0.8682
Brugia malayi prolyl oligopeptidase family protein 0.2047 0.3971 0.4638
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0004 0.0144
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.002 0.0002 0.0002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0078 0.0114 0.0114
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.0114 0.0114
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0214 0.0382 0.0382
Plasmodium falciparum plasmepsin IX 0.003 0.0021 0.006
Loa Loa (eye worm) hypothetical protein 0.044 0.0823 0.0961
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0031 0.0023 0.0023
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0114 0.0114
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0028 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0152 0.0259 0.0303
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1842 0.3571 0.3571
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Entamoeba histolytica acyl-CoA synthetase, putative 0.0158 0.0272 0.0762
Mycobacterium tuberculosis Conserved protein 0.0155 0.0265 0.1397
Schistosoma mansoni amine GPCR 0.0078 0.0114 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.1842 0.3571 0.417
Brugia malayi fibroinase precursor 0.044 0.0823 0.0961
Schistosoma mansoni growth hormone secretagogue receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis microtubule associated protein 2 0.5124 1 1
Brugia malayi GNS1/SUR4 family protein 0.002 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0004 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.044 0.0823 0.2306
Echinococcus multilocularis endothelin converting enzyme 1 0.0056 0.0071 0.0071
Echinococcus multilocularis muscleblind protein 1 0.0447 0.0838 0.0838
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.0182 0.0182
Echinococcus granulosus serotonin receptor 0.0078 0.0114 0.0114
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Probable hydrolase 0.0155 0.0265 0.1397
Echinococcus multilocularis tumor protein p63 0.1473 0.2848 0.2848
Mycobacterium ulcerans esterase/lipase LipP 0.0155 0.0265 0.8701
Trypanosoma cruzi cysteine peptidase, putative 0.1842 0.3571 0.417
Mycobacterium ulcerans hypothetical protein 0.0163 0.0281 0.9213
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0078 0.0114 0.0114
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Onchocerca volvulus Cathepsin F homolog 0.1842 0.3571 0.8991
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0158 0.0272 0.8934
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1662 0.3217 0.3217
Onchocerca volvulus 0.0078 0.0114 0.0288
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0004 0.0144
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0018 0.0022
Trichomonas vaginalis esterase, putative 0.0155 0.0265 0.0742
Toxoplasma gondii cathepsin CPC1 0.044 0.0823 0.2306
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0059 0.0077 0.0077
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0004 0.0012
Trypanosoma brucei oligopeptidase b 0.0175 0.0305 0.0853
Toxoplasma gondii hypothetical protein 0.0175 0.0305 0.0853
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0046 0.0053 0.028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0053 0.028
Mycobacterium tuberculosis Probable lipase LipE 0.0155 0.0265 0.1397
Schistosoma mansoni biogenic amine receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.0155 0.0265 0.0667
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0184 0.0323 0.0323
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0175 0.0305 0.0305
Toxoplasma gondii cathepsin CPC2 0.044 0.0823 0.2306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0158 0.0272 0.1434
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0052
Onchocerca volvulus 0.0054 0.0067 0.0169
Brugia malayi Protein phosphatase 2C containing protein 0.0103 0.0164 0.0192
Onchocerca volvulus 0.0078 0.0114 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.044 0.0823 0.2306
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0004 0.0023
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0569 0.1076 0.1257
Brugia malayi Cathepsin L-like precursor 0.1842 0.3571 0.417
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Plasmodium vivax vivapain-1 0.1008 0.1937 0.5425
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0078 0.0114 0.0134
Plasmodium falciparum plasmepsin X 0.003 0.0021 0.006
Entamoeba histolytica hypothetical protein 0.0112 0.0182 0.0509
Onchocerca volvulus 0.0078 0.0114 0.0288
Schistosoma mansoni voltage-gated potassium channel 0.0064 0.0087 0.0087
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0078 0.0114 0.0114
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0049 0.0124
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0004 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0004 0.0023
Echinococcus multilocularis neuropeptide receptor 0.0078 0.0114 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni biogenic amine receptor 0.0078 0.0114 0.0114
Plasmodium vivax serine-repeat antigen (SERA), putative 0.044 0.0823 0.2306
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0214 0.0382 0.1068
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0103 0.0164 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0114 0.0114
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.044 0.0823 0.0823
Entamoeba histolytica cysteine proteinase 1, putative 0.1008 0.1937 0.5425
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0078 0.0114 0.0134
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0097 0.0152 0.0426
Echinococcus granulosus neuropeptide receptor A26 0.0529 0.0999 0.0999
Plasmodium falciparum plasmepsin IV 0.0128 0.0213 0.0596
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0004 0.0144
Leishmania major eukaryotic initiation factor 4a, putative 0.0214 0.0382 0.1068
Giardia lamblia Cathepsin B precursor 0.1662 0.3217 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.044 0.0823 0.2306
Brugia malayi Heterochromatin protein 1 0.0074 0.0107 0.0125
Onchocerca volvulus 0.0078 0.0114 0.0288
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0046 0.0053 0.1745
Brugia malayi putative neuropeptide receptor NPR1 0.0078 0.0114 0.0134
Echinococcus granulosus tachykinin peptides receptor 99D 0.0078 0.0114 0.0114
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0031 0.0023 0.0023
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0155 0.0265 0.8701
Plasmodium falciparum serine repeat antigen 9 0.044 0.0823 0.2306
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0078 0.0114 0.0114
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0138 0.0232 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.044 0.0823 0.2306
Brugia malayi RE15519p 0.0078 0.0114 0.0134
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0078 0.0114 0.0114
Trichomonas vaginalis rotamase, putative 0.007 0.0099 0.0277
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0025
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0158 0.0272 0.8919
Loa Loa (eye worm) hypothetical protein 0.0447 0.0838 0.0979
Plasmodium vivax plasmepsin IV, putative 0.0128 0.0213 0.0596
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Schistosoma mansoni P2X receptor subunit 0.0044 0.0049 0.0049
Echinococcus granulosus endothelin converting enzyme 1 0.0056 0.0071 0.0071
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0046 0.0053 0.0149
Entamoeba histolytica hypothetical protein 0.0112 0.0182 0.0509
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0364 0.0676 0.079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Brugia malayi ORL1-like opioid receptor 0.0078 0.0114 0.0134
Giardia lamblia Cathepsin B precursor 0.044 0.0823 0.2559
Loa Loa (eye worm) hypothetical protein 0.0158 0.0272 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.044 0.0823 0.2306
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0118 0.0194 0.5
Schistosoma mansoni cathepsin B (C01 family) 0.044 0.0823 0.0823
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Onchocerca volvulus 0.0078 0.0114 0.0288
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0068 0.0096 0.0268
Giardia lamblia Cathepsin L precursor 0.044 0.0823 0.2559
Toxoplasma gondii cathepsin CPL 0.1842 0.3571 1
Onchocerca volvulus 0.0054 0.0067 0.0169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Giardia lamblia Cathepsin B precursor 0.044 0.0823 0.2559
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Plasmodium vivax vivapain-2 0.1842 0.3571 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Echinococcus multilocularis muscleblind protein 0.0447 0.0838 0.0838
Echinococcus granulosus neuropeptide receptor 0.0078 0.0114 0.0114
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.044 0.0823 0.2306
Plasmodium falciparum plasmepsin VIII, putative 0.003 0.0021 0.006
Plasmodium falciparum plasmepsin VII 0.003 0.0021 0.006
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.044 0.0823 0.0961
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0158 0.0272 0.8934
Brugia malayi cathepsin L precursor 0.044 0.0823 0.0961
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0004 0.0023
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0004 0.0144
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0004 0.0144
Plasmodium falciparum serine repeat antigen 8 0.044 0.0823 0.2306
Giardia lamblia Cathepsin L-like protease 0.044 0.0823 0.2559
Brugia malayi cathepsin L-like cysteine proteinase 0.044 0.0823 0.0961
Giardia lamblia Cysteine protease 0.044 0.0823 0.2559
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0018 0.0022
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0056 0.0071 0.0071
Plasmodium vivax vivapain-3 0.1008 0.1937 0.5425
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Schistosoma mansoni neuropeptide receptor 0.0078 0.0114 0.0114
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Schistosoma mansoni cathepsin D (A01 family) 0.0378 0.0702 0.0702
Plasmodium vivax acetyl-CoA synthetase, putative 0.0046 0.0053 0.0149
Echinococcus multilocularis cathepsin L 0.1008 0.1937 0.1937
Loa Loa (eye worm) hypothetical protein 0.0102 0.0162 0.0189
Plasmodium falciparum plasmepsin V 0.003 0.0021 0.006
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.0114 0.0114
Plasmodium falciparum fatty acid elongation protein, GNS1/SUR4 family, putative 0.002 0.0001 0.0003
Echinococcus granulosus cathepsin L 0.044 0.0823 0.0823
Schistosoma mansoni amine GPCR 0.0078 0.0114 0.0114
Echinococcus granulosus intermediate filament protein 0.0054 0.0067 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.0114 0.0134
Echinococcus granulosus expressed protein 0.007 0.0099 0.0099
Plasmodium falciparum serine repeat antigen 1 0.044 0.0823 0.2306
Schistosoma mansoni voltage-gated potassium channel 0.0064 0.0087 0.0087
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.007 0.0099 0.0115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0138 0.0232 0.0651
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0004 0.0144
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0046 0.0053 0.0149
Mycobacterium ulcerans hypothetical protein 0.0108 0.0173 0.5694
Trypanosoma cruzi hypothetical protein, conserved 0.0155 0.0265 0.031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0043 0.1405
Loa Loa (eye worm) hypothetical protein 0.0032 0.0025 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.044 0.0823 0.2306
Plasmodium vivax aspartyl protease, putative 0.003 0.0021 0.006
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0046 0.0053 0.1745
Brugia malayi hypothetical protein 0.003 0.0021 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0107 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.002 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0009 0.0025
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.2047 0.3971 1
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0175 0.0305 0.1605
Echinococcus multilocularis p2X purinoceptor 4 0.0044 0.0049 0.0049
Toxoplasma gondii peptidase family M13 protein 0.0056 0.0071 0.0199
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1008 0.1937 0.2262
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0112 0.0181 0.0955
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0021 0.006
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0025 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.0114 0.0114
Echinococcus multilocularis g-protein coupled receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Leishmania major cysteine peptidase A (CPA) 0.1842 0.3571 1
Mycobacterium leprae conserved hypothetical protein 0.0155 0.0265 0.8682
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1662 0.3217 0.3757
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0046 0.0053 0.1745
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0052
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0128 0.0213 0.0596
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) papain family cysteine protease containing protein 0.044 0.0823 0.0961
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0175 0.0305 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0078 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0175 0.0305 0.0853
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0155 0.0265 0.0265
Schistosoma mansoni sphingosine kinase A B 0.0163 0.0281 0.0281
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0214 0.0382 0.0382
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.1008 0.1937 0.5425
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Brugia malayi Angiotensin-converting enzyme family protein 0.0364 0.0676 0.079
Plasmodium vivax unspecified product 0.0569 0.1076 0.3013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0004 0.0144
Mycobacterium ulcerans zinc metalloprotease 0.0056 0.0071 0.2327
Schistosoma mansoni neuropeptide receptor 0.0078 0.0114 0.0114
Schistosoma mansoni lamin 0.0054 0.0067 0.0067
Schistosoma mansoni opsin-like receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.0114 0.0114
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0026 0.0031
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0819 0.1566 0.1829
Loa Loa (eye worm) hypothetical protein 0.0567 0.1073 0.1253
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.2047 0.3971 0.3971
Plasmodium falciparum peptidase, putative 0.0175 0.0305 0.0853
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0098 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1008 0.1937 0.5425
Plasmodium falciparum serine repeat antigen 6 0.044 0.0823 0.2306
Toxoplasma gondii propionate-CoA ligase 0.0046 0.0053 0.0149
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.044 0.0823 0.2559
Toxoplasma gondii aspartyl protease 0.003 0.0021 0.006
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Echinococcus multilocularis neuropeptide receptor 0.0078 0.0114 0.0114
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0138 0.0232 0.0651
Echinococcus granulosus G protein coupled receptor 139 0.0078 0.0114 0.0114
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0184 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0052
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0004 0.0023
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0819 0.1566 0.1566
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.044 0.0823 0.0961
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0175 0.0305 0.0305
Trypanosoma cruzi prolyl endopeptidase 0.0175 0.0305 0.0356
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0004 0.0144
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0158 0.0272 0.8934
Brugia malayi Cathepsin L-like precursor 0.1274 0.2457 0.2869
Loa Loa (eye worm) hypothetical protein 0.0056 0.0071 0.0083
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0046 0.0053 0.0149
Trichomonas vaginalis set domain proteins, putative 0.1463 0.2829 0.7921
Loa Loa (eye worm) hypothetical protein 0.0569 0.1076 0.1257
Schistosoma mansoni lamin 0.0054 0.0067 0.0067
Schistosoma mansoni amine GPCR 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Conserved protein 0.0155 0.0265 0.1397
Schistosoma mansoni sphingoid long chain base kinase 0.0163 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.044 0.0823 0.0961
Giardia lamblia Cathepsin L precursor 0.044 0.0823 0.2559
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0043 0.1405
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0128 0.0213 0.0213
Entamoeba histolytica hypothetical protein, conserved 0.0163 0.0281 0.0786
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Brugia malayi larval opioid receptor 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.1274 0.2457 0.2869
Echinococcus granulosus acylamino acid releasing enzyme 0.0175 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Echinococcus granulosus biogenic amine 5HT receptor 0.0078 0.0114 0.0114
Trypanosoma cruzi cysteine proteinase, putative 0.1008 0.1937 0.2262
Brugia malayi G protein-coupled receptor F59B2.13 0.0078 0.0114 0.0134
Schistosoma mansoni amine GPCR 0.0078 0.0114 0.0114
Plasmodium vivax vivapain-2 0.1842 0.3571 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0078 0.0114 0.0134
Echinococcus granulosus cathepsin l1 0.1274 0.2457 0.2457
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.0114 0.0114
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0062
Loa Loa (eye worm) hypothetical protein 0.0042 0.0044 0.0052
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.0182 0.0182
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0025
Brugia malayi Dopamine receptor 0.0078 0.0114 0.0134
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni neuropeptide f receptor 76f 0.0078 0.0114 0.0114
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0053 0.1745
Giardia lamblia Alanyl dipeptidyl peptidase 0.0175 0.0305 0.0947
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0078 0.0114 0.0114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0053 0.0062
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0155 0.0265 0.031
Onchocerca volvulus 0.1842 0.3571 0.8991
Echinococcus multilocularis cathepsin b 0.4391 0.8563 0.8563
Echinococcus multilocularis neuropeptide s receptor 0.0529 0.0999 0.0999
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0095 0.0111
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0107 0.0299
Onchocerca volvulus 0.1274 0.2457 0.6187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1008 0.1937 0.5425
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0046 0.0053 0.0062
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0049 0.0139
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.0114 0.0114
Echinococcus granulosus sex peptide receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Brugia malayi neuropeptide F receptor 0.0078 0.0114 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.044 0.0823 0.2306
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis orexin receptor type 2 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0138 0.0232 0.0271
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0002 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1842 0.3571 0.417
Onchocerca volvulus 0.0158 0.0272 0.0685
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0046 0.0053 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0236 0.0425 0.0496
Onchocerca volvulus 0.0078 0.0114 0.0288
Schistosoma mansoni memapsin-2 (A01 family) 0.003 0.0021 0.0021
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0175 0.0305 0.0853
Loa Loa (eye worm) hypothetical protein 0.0118 0.0194 0.0226
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.001
Schistosoma mansoni chromobox protein 0.0074 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0099 0.0277
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0019
Brugia malayi Cathepsin L-like precursor 0.1842 0.3571 0.417
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0098 0.0115
Giardia lamblia Alanyl dipeptidyl peptidase 0.0175 0.0305 0.0947
Echinococcus granulosus cathepsin b 0.4391 0.8563 0.8563
Trypanosoma brucei hypothetical protein, conserved 0.0155 0.0265 0.0742
Echinococcus granulosus g protein coupled receptor 0.0078 0.0114 0.0114
Echinococcus granulosus neuropeptide s receptor 0.0529 0.0999 0.0999
Plasmodium vivax unspecified product 0.1008 0.1937 0.5425
Loa Loa (eye worm) cathepsin B 0.1662 0.3217 0.3757
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.031
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0002 0.0002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0046 0.0053 0.0062
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0056 0.0071 0.0083
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Leishmania major fatty acid elongase, putative 0.002 0.0001 0.0003
Trichomonas vaginalis antibiotic synthetase, putative 0.0046 0.0053 0.0149
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0114 0.0114
Plasmodium falciparum serine repeat antigen 5 0.044 0.0823 0.2306
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1286 0.2481 0.2897
Trypanosoma cruzi fatty acid elongase, putative 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0056 0.0071 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.044 0.0823 0.2306
Schistosoma mansoni amine GPCR 0.0078 0.0114 0.0114
Trypanosoma cruzi oligopeptidase b 0.0175 0.0305 0.0356
Brugia malayi Serotonin receptor 0.0078 0.0114 0.0134
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0041 0.0043 0.0043
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0138 0.0232 0.0271
Plasmodium vivax GNS1/SUR4 domain containing protein 0.002 0.0001 0.0003
Schistosoma mansoni myosin xvIII 0.0078 0.0114 0.0114
Schistosoma mansoni biogenic amine (5HT) receptor 0.0078 0.0114 0.0114
Giardia lamblia Cysteine protease 0.044 0.0823 0.2559
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0819 0.1566 0.1829
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.0823 0.0823
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0569 0.1076 0.1257
Plasmodium falciparum acyl-CoA synthetase 0.0118 0.0194 0.0543
Loa Loa (eye worm) hypothetical protein 0.0954 0.1831 0.2138
Echinococcus granulosus p2X purinoceptor 4 0.0044 0.0049 0.0049
Onchocerca volvulus 0.0078 0.0114 0.0288
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0112 0.0181 0.0955
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0214 0.0382 0.1068
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0068 0.0096 0.0112
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni rotamase 0.007 0.0099 0.0099
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0026 0.0031
Loa Loa (eye worm) melatonin receptor type 1A 0.0078 0.0114 0.0134
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.044 0.0823 0.2306
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0569 0.1076 0.1257
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.0114 0.0114
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0046 0.0053 0.028
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0078 0.0114 0.0134
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0002 0.0002
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0152 0.0426
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0004 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0158 0.0272 0.0762
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.0114 0.0114
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0214 0.0382 0.0382
Trypanosoma cruzi hypothetical protein, conserved 0.0155 0.0265 0.031
Loa Loa (eye worm) peptidase family M13 containing protein 0.0041 0.0042 0.005
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.005
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Echinococcus granulosus peptide allatostatin:somatostatin 0.0078 0.0114 0.0114
Brugia malayi Cathepsin L-like precursor 0.1842 0.3571 0.417
Echinococcus granulosus tm gpcr rhodopsin 0.0322 0.0593 0.0593
Onchocerca volvulus 0.0049 0.0058 0.0145
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Loa Loa (eye worm) hypothetical protein 0.4391 0.8563 1
Trichomonas vaginalis D-aminoacylase, putative 0.0155 0.0265 0.0742
Loa Loa (eye worm) hypothetical protein 0.0216 0.0385 0.0449
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0742 0.1415 0.3963
Plasmodium falciparum eukaryotic initiation factor 4A 0.0214 0.0382 0.1068
Loa Loa (eye worm) fatty acid elongation protein 3 0.002 0.0001 0.0001
Toxoplasma gondii integral membrane protein, GNS1/SUR4 family protein, putative 0.002 0.0001 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0031 0.0036
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0025 0.0029
Toxoplasma gondii ABC1 family protein 0.0155 0.0265 0.0742
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0138 0.0232 0.0651
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0107 0.0125
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0175 0.0305 0.0356
Echinococcus granulosus cathepsin b 0.4391 0.8563 0.8563
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0031 0.0023 0.0023
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0078 0.0114 0.0114
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0004 0.0012
Trypanosoma cruzi fatty acid elongase, putative 0.002 0.0001 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.0158 0.0272 0.0762
Brugia malayi cathepsin B-like cysteine proteinase 0.4391 0.8563 1
Echinococcus granulosus tumor protein p63 0.1473 0.2848 0.2848
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0322 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0054 0.0067 0.0078
Mycobacterium ulcerans hypothetical protein 0.0138 0.0232 0.7626
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0214 0.0382 0.0446
Schistosoma mansoni hypothetical protein 0.007 0.0098 0.0098
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0005
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0046 0.0053 0.0062
Brugia malayi Cathepsin L-like cysteine proteinase 0.1274 0.2457 0.2869
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Plasmodium vivax serine-repeat antigen (SERA) 0.044 0.0823 0.2306
Plasmodium vivax hypothetical protein, conserved 0.0155 0.0265 0.0742
Schistosoma mansoni opsin-like receptor 0.0078 0.0114 0.0114
Echinococcus granulosus p2X purinoceptor 4 0.0044 0.0049 0.0049
Entamoeba histolytica prolyl oligopeptidase family protein 0.0175 0.0305 0.0853
Loa Loa (eye worm) hypothetical protein 0.0128 0.0213 0.0249
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0175 0.0305 0.0853
Entamoeba histolytica prolyl oligopeptidase family protein 0.0175 0.0305 0.0853
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0049 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Schistosoma mansoni alpha-1 adrenergic receptor 0.0078 0.0114 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1008 0.1937 0.5425
Trypanosoma cruzi major cysteine proteinase, putative 0.044 0.0823 0.0961
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Brugia malayi prolyl oligopeptidase family protein 0.0819 0.1566 0.1829
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0041 0.0043 0.0226
Schistosoma mansoni acetyl-CoA synthetase 0.0046 0.0053 0.0053
Onchocerca volvulus Protein phosphatase 1D homolog 0.0103 0.0164 0.0414
Plasmodium falciparum plasmepsin I 0.0128 0.0213 0.0596
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Echinococcus multilocularis p2X purinoceptor 4 0.0044 0.0049 0.0049
Mycobacterium tuberculosis Conserved protein 0.0155 0.0265 0.1397
Trichomonas vaginalis conserved hypothetical protein 0.044 0.0823 0.2306
Entamoeba histolytica prolyl oligopeptidase family protein 0.0175 0.0305 0.0853
Mycobacterium ulcerans beta-lactamase 0.0155 0.0265 0.8701
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0025 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.1274 0.2457 0.6881
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0197 0.0347 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.002 0.0055
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Brugia malayi G-protein coupled receptor 0.0078 0.0114 0.0134
Echinococcus multilocularis lamin dm0 0.0054 0.0067 0.0067
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0053 0.028
Toxoplasma gondii aldehyde dehydrogenase 0.0041 0.0043 0.012
Echinococcus multilocularis somatostatin receptor 0.0078 0.0114 0.0114
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0155 0.0265 0.0265
Plasmodium vivax RNA helicase-1, putative 0.0214 0.0382 0.1068
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0078 0.0114 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Schistosoma mansoni hypothetical protein 0.0078 0.0114 0.0114
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma brucei Fatty acid elongase 0.002 0.0001 0.0003
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0046 0.0053 0.0149
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0184 0.0323 0.0378
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Loa Loa (eye worm) hypothetical protein 0.1842 0.3571 0.417
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0078 0.0114 0.0114
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Brugia malayi Cytochrome P450 family protein 0.0033 0.0026 0.0031
Entamoeba histolytica cysteine proteinase, putative 0.1842 0.3571 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Trypanosoma brucei prolyl endopeptidase 0.0175 0.0305 0.0853
Giardia lamblia Cathepsin B precursor 0.044 0.0823 0.2559
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.0043 0.0043
Brugia malayi Cathepsin L-like precursor 0.1842 0.3571 0.417
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0121
Loa Loa (eye worm) hypothetical protein 0.0118 0.0194 0.0226
Schistosoma mansoni P2X receptor subunit 0.0044 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0158 0.0272 0.8919
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0026 0.0858
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0053 0.028
Loa Loa (eye worm) oxidoreductase 0.0046 0.0053 0.0062
Mycobacterium tuberculosis Probable esterase LipL 0.0155 0.0265 0.1397
Echinococcus granulosus biogenic amine 5HT receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0004 0.0144
Leishmania major cathepsin L-like protease 0.1842 0.3571 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium tuberculosis Probable peptidase 0.0175 0.0305 0.1605
Onchocerca volvulus 0.1463 0.2829 0.7122
Echinococcus multilocularis allatostatin A receptor 0.0078 0.0114 0.0114
Entamoeba histolytica cysteine proteinase, putative 0.1008 0.1937 0.5425
Plasmodium vivax aspartyl protease, putative 0.003 0.0021 0.006
Brugia malayi beta-lactamase family protein 0.0155 0.0265 0.031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0021 0.0021
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0004 0.0023
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0053 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Brugia malayi Pepsin A precursor 0.003 0.0021 0.0025
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0004 0.0023
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0138 0.0232 0.0651
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0178 0.031 0.031
Echinococcus multilocularis voltage gated potassium channel 0.002 0.0002 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1008 0.1937 0.5425
Onchocerca volvulus 0.003 0.0021 0.0054
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0046 0.0053 0.028
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0205 0.0363 0.1018
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0013 0.0013
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0053 0.1624
Echinococcus granulosus g protein coupled receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis GPCR, family 2 0.0032 0.0025 0.0025
Echinococcus multilocularis 0.0022 0.0004 0.0004
Schistosoma mansoni opsin-like receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) prolyl oligopeptidase 0.2047 0.3971 0.4638
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.2457 0.6881
Loa Loa (eye worm) cysteine protease 0.1842 0.3571 0.417
Echinococcus granulosus Dipeptidyl peptidase 9 0.0819 0.1566 0.1566
Echinococcus granulosus dro:myosuppressin receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0954 0.1831 0.2138
Mycobacterium ulcerans acyl-CoA synthetase 0.0158 0.0272 0.8934
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0214 0.0382 0.0446
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0004 0.0023
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0021 0.0004 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.031
Schistosoma mansoni cathepsin F (C01 family) 0.1842 0.3571 0.3571
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Schistosoma mansoni neuropeptide receptor 0.0078 0.0114 0.0114
Schistosoma mansoni cathepsin F (C01 family) 0.1842 0.3571 0.3571
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0819 0.1566 0.4386
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.0043 0.0043
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0012
Loa Loa (eye worm) aspartic protease BmAsp-1 0.003 0.0021 0.0025
Brugia malayi G-protein coupled receptor 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.044 0.0823 0.0961
Brugia malayi Cathepsin L-like precursor 0.1842 0.3571 0.417
Entamoeba histolytica cysteine protease, putative 0.044 0.0823 0.2306
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0138 0.0232 0.0271
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0004 0.0023
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0046 0.0053 0.0149
Brugia malayi Papain family cysteine protease containing protein 0.1008 0.1937 0.2262
Entamoeba histolytica cysteine proteinase, putative 0.1842 0.3571 1
Echinococcus multilocularis cathepsin L cysteine protease 0.1842 0.3571 0.3571
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0078 0.0114 0.0114
Brugia malayi hypothetical protein 0.0567 0.1073 0.1253
Echinococcus multilocularis p2X purinoceptor 4 0.0044 0.0049 0.0049
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0046 0.0053 0.0062
Schistosoma mansoni neuropeptide receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0026 0.0031
Brugia malayi sulfakinin receptor protein 0.0078 0.0114 0.0134
Treponema pallidum ATP-dependent RNA helicase 0.0214 0.0382 1
Plasmodium falciparum plasmepsin VI 0.0128 0.0213 0.0596
Trichomonas vaginalis penicillin-binding protein, putative 0.0155 0.0265 0.0742
Onchocerca volvulus 0.1842 0.3571 0.8991
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1662 0.3217 0.9009
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0051 0.0062 0.0173
Echinococcus granulosus cathepsin L cysteine protease 0.1008 0.1937 0.1937
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1842 0.3571 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Schistosoma mansoni hypothetical protein 0.0022 0.0004 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.0182 0.0182
Echinococcus granulosus somatostatin receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0013
Giardia lamblia Hypothetical protein 0.044 0.0823 0.2559
Mycobacterium ulcerans short chain dehydrogenase 0.0166 0.0288 0.9449
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0021 0.0004 0.001
Echinococcus granulosus fmrfamide receptor 0.0078 0.0114 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0175 0.0305 0.0853
Trypanosoma cruzi fatty acid elongase, putative 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0175 0.0305 0.0853
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Schistosoma mansoni hypothetical protein 0.0078 0.0114 0.0114
Loa Loa (eye worm) cytochrome P450 0.0022 0.0004 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Brugia malayi follicle stimulating hormone receptor 0.0078 0.0114 0.0134
Trypanosoma cruzi fatty acid elongase, putative 0.002 0.0001 0.0001
Plasmodium vivax acyl-CoA synthetase, putative 0.0118 0.0194 0.0543
Entamoeba histolytica hypothetical protein 0.044 0.0823 0.2306
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.0114 0.0114
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0078 0.0114 0.0134
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0068 0.0096 0.0268
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.0823 0.0823
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0062
Brugia malayi hypothetical protein 0.0152 0.0259 0.0303
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.044 0.0823 0.2306
Giardia lamblia Cathepsin L precursor 0.044 0.0823 0.2559
Brugia malayi Pre-SET motif family protein 0.0184 0.0323 0.0378
Plasmodium falciparum plasmepsin III 0.003 0.0021 0.006
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0152 0.0178
Entamoeba histolytica cysteine proteinase 2 0.1008 0.1937 0.5425
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1274 0.2457 0.6881
Echinococcus multilocularis beta LACTamase domain containing family member 0.0155 0.0265 0.0265
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.044 0.0823 0.2306
Brugia malayi AMP-binding enzyme family protein 0.0158 0.0272 0.0318
Echinococcus multilocularis chromobox protein 1 0.0074 0.0107 0.0107
Toxoplasma gondii cathepsin B 0.1662 0.3217 0.9009
Echinococcus multilocularis sex peptide receptor 0.0078 0.0114 0.0114
Entamoeba histolytica hypothetical protein 0.0112 0.0182 0.0509
Trypanosoma brucei prolyl oligopeptidase, putative 0.0175 0.0305 0.0853
Mycobacterium ulcerans hypothetical protein 0.0158 0.0272 0.8934
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.044 0.0823 0.2306
Onchocerca volvulus 0.0155 0.0265 0.0667
Brugia malayi chromobox protein homolog 3 0.0041 0.0043 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.044 0.0823 0.2306
Brugia malayi Papain family cysteine protease containing protein 0.1008 0.1937 0.2262
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0004 0.0144
Brugia malayi prolyl oligopeptidase family protein 0.0175 0.0305 0.0356
Schistosoma mansoni neprilysin-2 (M13 family) 0.0028 0.0017 0.0017
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.044 0.0823 0.2306
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0175 0.0305 0.0853
Echinococcus multilocularis cathepsin L 0.044 0.0823 0.0823
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0214 0.0382 0.0382
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0004 0.0144
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Plasmodium vivax serine-repeat antigen (SERA) 0.044 0.0823 0.2306
Echinococcus granulosus neuropeptide FF receptor 2 0.0078 0.0114 0.0114
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0067 0.0078
Echinococcus granulosus GPCR family 2 0.0032 0.0025 0.0025
Entamoeba histolytica cysteine protease, putative 0.044 0.0823 0.2306
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0214 0.0382 0.096
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0214 0.0382 0.2011
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0067 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0158 0.0272 0.0318
Echinococcus granulosus lamin dm0 0.0054 0.0067 0.0067
Onchocerca volvulus 0.0078 0.0114 0.0288
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1008 0.1937 0.5425
Onchocerca volvulus 0.003 0.0021 0.0054
Trypanosoma cruzi oligopeptidase b 0.0175 0.0305 0.0356
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0175 0.0305 1
Echinococcus multilocularis fmrfamide receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.0078 0.0114 0.0288
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0046 0.0053 0.0053
Mycobacterium tuberculosis Probable lipase LipD 0.0155 0.0265 0.1397
Echinococcus granulosus prolyl endopeptidase 0.0175 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Loa Loa (eye worm) transcription factor SMAD2 0.0236 0.0425 0.0496
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.0823 0.0823
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0046 0.0053 0.028
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0025 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0004 0.0023
Giardia lamblia Cathepsin B precursor 0.1662 0.3217 1
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0138 0.0232 0.0651
Trypanosoma cruzi cysteine peptidase, putative 0.1008 0.1937 0.2262
Brugia malayi aspartic protease BmAsp-2, identical 0.003 0.0021 0.0025
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0138 0.0232 0.0271
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.2047 0.3971 0.3971
Entamoeba histolytica hypothetical protein, conserved 0.0175 0.0305 0.0853
Mycobacterium ulcerans acetyl-CoA synthetase 0.0046 0.0053 0.1745
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.044 0.0823 0.2306
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0056 0.0071 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.0114 0.0114
Brugia malayi hypothetical protein 0.0112 0.0182 0.0212
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0026 0.0031
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0046 0.0053 0.1745
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Toxoplasma gondii hypothetical protein 0.0033 0.0027 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.005
Onchocerca volvulus 0.0078 0.0114 0.0288
Loa Loa (eye worm) hypothetical protein 0.0447 0.0838 0.0979
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1842 0.3571 1
Giardia lamblia Encystation-specific protease 0.044 0.0823 0.2559
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0029 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.031
Brugia malayi cathepsin F-like cysteine proteinase 0.044 0.0823 0.0961
Schistosoma mansoni hypothetical protein 0.0032 0.0025 0.0025
Echinococcus granulosus cathepsin L cysteine proteinase 0.1842 0.3571 0.3571
Brugia malayi intermediate filament protein 0.0054 0.0067 0.0078
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.0114 0.0134
Plasmodium falciparum cysteine proteinase falcipain 1 0.1008 0.1937 0.5425
Giardia lamblia Cysteine protease 0.044 0.0823 0.2559
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0004 0.0144
Trypanosoma cruzi cysteine peptidase, putative 0.1842 0.3571 0.417
Brugia malayi beta-lactamase family protein 0.0155 0.0265 0.031
Echinococcus granulosus allatostatin A receptor 0.0078 0.0114 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0031 0.0023 0.0023
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0004 0.0004
Onchocerca volvulus 0.1842 0.3571 0.8991
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4391 0.8563 0.8563
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0031 0.0023 0.0023
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0214 0.0382 0.1068
Echinococcus multilocularis G protein coupled receptor 139 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0155 0.0265 0.1397
Loa Loa (eye worm) ctsf protein 0.1842 0.3571 0.417
Echinococcus granulosus chromobox protein 1 0.0074 0.0107 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0175 0.0305 0.0356
Giardia lamblia Cathepsin L precursor 0.044 0.0823 0.2559
Giardia lamblia Cathepsin B precursor 0.044 0.0823 0.2559
Giardia lamblia Dipeptidyl-peptidase I precursor 0.044 0.0823 0.2559
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0078 0.0114 0.0114
Onchocerca volvulus 0.0028 0.0016 0.004
Brugia malayi cahepsin L-like non-peptiedase homolog 0.044 0.0823 0.0961
Echinococcus multilocularis G-protein coupled receptor, putative 0.0078 0.0114 0.0114
Echinococcus multilocularis fmrfamide receptor 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0118 0.0194 0.0226
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0118 0.0194 0.6361
Brugia malayi Serotonin receptor 0.0078 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0162 0.0189
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.044 0.0823 0.0823
Plasmodium falciparum plasmepsin II 0.0128 0.0213 0.0596
Loa Loa (eye worm) hypothetical protein 0.0053 0.0065 0.0076
Echinococcus multilocularis expressed protein 0.007 0.0099 0.0099
Echinococcus granulosus orexin receptor type 2 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Onchocerca volvulus 0.0078 0.0114 0.0288
Loa Loa (eye worm) hypothetical protein 0.0214 0.0382 0.0446
Brugia malayi prolyl oligopeptidase family protein 0.0175 0.0305 0.0356
Toxoplasma gondii aspartyl protease ASP1 0.0128 0.0213 0.0596
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1842 0.3571 1
Trypanosoma cruzi major cysteine proteinase, putative 0.044 0.0823 0.0961
Entamoeba histolytica cysteine protease, putative 0.044 0.0823 0.2306
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0004 0.0023
Giardia lamblia Cathepsin L precursor 0.044 0.0823 0.2559
Leishmania major eukaryotic initiation factor 4a, putative 0.0214 0.0382 0.1068
Loa Loa (eye worm) hypothetical protein 0.0252 0.0456 0.0532
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis musashi 0.0054 0.0067 0.0067
Trichomonas vaginalis rotamase, putative 0.0068 0.0096 0.0268
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0155 0.0265 0.031
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1842 0.3571 1
Leishmania major cytochrome p450-like protein 0.0033 0.0026 0.0073
Loa Loa (eye worm) hypothetical protein 0.0175 0.0305 0.0356
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Brugia malayi Dopamine receptor protein 2 0.0078 0.0114 0.0134
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4391 0.8563 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0175 0.0305 0.0305
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0078 0.0114 0.0114
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.044 0.0823 0.2306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0078 0.0114 0.0114
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.044 0.0823 0.2306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.044 0.0823 0.2306
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma cruzi cysteine peptidase, putative 0.1842 0.3571 0.417
Entamoeba histolytica papain family cysteine protease domain containing protein 0.044 0.0823 0.2306
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0078 0.0114 0.0114
Brugia malayi Cathepsin L-like precursor 0.1842 0.3571 0.417
Onchocerca volvulus 0.0078 0.0114 0.0288
Mycobacterium ulcerans hypothetical protein 0.0155 0.0265 0.8701
Brugia malayi cathepsin L-like precursor 0.1274 0.2457 0.2869
Mycobacterium tuberculosis Conserved protein 0.0163 0.0281 0.1479
Brugia malayi Papain family cysteine protease containing protein 0.044 0.0823 0.0961
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1842 0.3571 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0059 0.0077 0.009
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0819 0.1566 0.4386
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0163 0.0281 0.0328
Loa Loa (eye worm) fibroinase 0.1842 0.3571 0.417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Brugia malayi putative neuropeptide receptor 0.0078 0.0114 0.0134
Giardia lamblia Dipeptidyl-peptidase I precursor 0.044 0.0823 0.2559
Onchocerca volvulus 0.1842 0.3571 0.8991
Brugia malayi Eukaryotic aspartyl protease family protein 0.003 0.0021 0.0025
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0046 0.0053 0.0062
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0184 0.0323 0.0906
Leishmania major acetyl-CoA synthetase, putative 0.0046 0.0053 0.0149
Entamoeba histolytica cysteine protease, putative 0.1008 0.1937 0.5425
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0112 0.0181 0.0955
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.044 0.0823 0.0961
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.044 0.0823 0.2306
Schistosoma mansoni hypothetical protein 0.0032 0.0025 0.0025
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0214 0.0382 0.1186
Trypanosoma cruzi hypothetical protein, conserved 0.0175 0.0305 0.0356
Trichomonas vaginalis penicillin-binding protein, putative 0.0155 0.0265 0.0742
Onchocerca volvulus 0.0046 0.0053 0.0134
Plasmodium falciparum serine repeat antigen 2 0.044 0.0823 0.2306
Brugia malayi hypothetical protein 0.0078 0.0114 0.0134
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0046 0.0053 0.1624
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0819 0.1566 0.1566
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0041 0.0043 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0114 0.0114
Schistosoma mansoni chromobox protein 0.0074 0.0107 0.0107
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0028 0.0017 0.0017
Echinococcus multilocularis lamin 0.0054 0.0067 0.0067
Brugia malayi GnHR receptor homolog 0.0078 0.0114 0.0134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4391 0.8563 0.8563
Brugia malayi Melatonin receptor type 1A 0.0078 0.0114 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0004 0.0023
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0004 0.001
Plasmodium vivax SET domain protein, putative 0.0184 0.0323 0.0906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.044 0.0823 0.2306
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0078 0.0114 0.0114
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1842 0.3571 0.3571
Loa Loa (eye worm) aspartyl protease 6 0.003 0.0021 0.0025
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0004 0.0144
Echinococcus granulosus cathepsin l1 0.1842 0.3571 0.3571
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Onchocerca volvulus Cathepsin L homolog 0.044 0.0823 0.2073
Brugia malayi Dopamine receptor protein 1 0.0078 0.0114 0.0134
Brugia malayi hypothetical protein 0.0024 0.0009 0.001
Brugia malayi cathepsin F-like cysteine proteinase 0.0569 0.1076 0.1257
Onchocerca volvulus Neuropeptide F receptor homolog 0.0078 0.0114 0.0288
Schistosoma mansoni adenoreceptor 0.0078 0.0114 0.0114
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0005
Echinococcus granulosus 7tm_1 domain containing protein 0.0078 0.0114 0.0114
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0046 0.0053 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.044 0.0823 0.2306
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0046 0.0053 0.1745
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0046 0.0053 0.1745
Trichomonas vaginalis D-aminoacylase, putative 0.0155 0.0265 0.0742
Echinococcus multilocularis dro:myosuppressin receptor 0.0078 0.0114 0.0114
Schistosoma mansoni cathepsin F (C01 family) 0.1274 0.2457 0.2457
Brugia malayi Cathepsin L-like precursor 0.0569 0.1076 0.1257
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0175 0.0305 0.0305
Loa Loa (eye worm) GNS1/SUR4 family protein 0.002 0.0001 0.0001
Onchocerca volvulus 0.0078 0.0114 0.0288
Onchocerca volvulus 0.0197 0.0347 0.0874
Brugia malayi Cytochrome P450 family protein 0.0022 0.0004 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0009 0.0025
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0053 0.0062
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0078 0.0114 0.0134
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0053 0.1745
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0078 0.0114 0.0288
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.004 0.0041 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0175 0.0305 0.0853
Loa Loa (eye worm) hypothetical protein 0.1274 0.2457 0.2869
Onchocerca volvulus 0.0078 0.0114 0.0288
Toxoplasma gondii aspartyl protease ASP3 0.003 0.0021 0.006
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1008 0.1937 0.1937
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0004 0.0023
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0068 0.0096 0.0112
Echinococcus granulosus cathepsin L 0.1008 0.1937 0.1937
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1274 0.2457 0.2869
Loa Loa (eye worm) hypothetical protein 0.0118 0.0194 0.0226
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0068 0.0096 0.0268
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0128 0.0213 0.0596
Brugia malayi Cytochrome P450 family protein 0.0033 0.0026 0.0031
Brugia malayi Papain family cysteine protease containing protein 0.1842 0.3571 0.417
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Toxoplasma gondii peptidylprolyl isomerase 0.0068 0.0096 0.0268
Trichomonas vaginalis antibiotic synthetase, putative 0.0046 0.0053 0.0149
Echinococcus granulosus cysteine protease 0.1008 0.1937 0.1937
Echinococcus granulosus alpha 1A adrenergic receptor 0.0078 0.0114 0.0114
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0128 0.0213 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1842 0.3571 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0114 0.0134
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0046 0.0053 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.044 0.0823 0.2306

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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