Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0005 | 0.0002 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0019 | 0.0089 | 0.0098 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.0444 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0018 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0022 | 0.0108 | 0.0119 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0073 | 0.0078 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.023 | 0.023 |
Schistosoma mansoni | ets | 0.0011 | 0.0041 | 0.0045 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1962 | 0.2164 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0056 | 0.0318 | 0.035 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0298 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0376 | 0.0414 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0116 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0028 | 0.0028 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0035 | 0.0035 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0028 | 0.003 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0022 | 0.0108 | 0.0119 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.0411 | 0.2525 | 0.2784 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.0997 | 0.11 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.0582 | 0.3585 | 1 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | Ets-domain containing protein | 0.0011 | 0.0041 | 0.0045 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | DR-78 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.0444 | 0.0444 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.006 | 0.0344 | 0.0379 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Leishmania major | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0349 | 0.2138 | 0.2358 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1962 | 0.2164 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0005 | 0.0002 | 0.0002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.023 | 0.0254 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0056 | 0.0318 | 0.1257 |
Brugia malayi | conserved hypotetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0151 | 0.0166 |
Echinococcus granulosus | muscleblind protein | 0.032 | 0.1962 | 0.2164 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0011 | 0.0041 | 0.0045 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.0411 | 0.2525 | 0.2784 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0045 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.031 | 0.0342 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1188 | 0.1309 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0428 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.0582 | 0.3585 | 0.3952 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0005 | 0.0004 | 0.0004 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0074 | 0.0434 | 0.0479 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0122 | 0.0134 |
Brugia malayi | Polyprenyl synthetase family protein | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0351 | 0.0387 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1188 | 0.1309 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Schistosoma mansoni | trans-prenyltransferase | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | geminin | 0.0196 | 0.1188 | 0.1309 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0035 | 0.0035 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0027 | 0.003 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0005 | 0.0002 | 0.0002 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0035 | 0.0038 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0011 | 0.0041 | 0.0045 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.0411 | 0.2525 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | glutathione synthetase | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0723 | 0.0797 |
Echinococcus multilocularis | muscleblind protein | 0.032 | 0.1962 | 0.1962 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | protein C ets 2 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0017 | 0.0018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 0.907 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Echinococcus multilocularis | ets variant gene 4 | 0.0011 | 0.0041 | 0.0041 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3585 |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.0444 | 0.049 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0005 | 0.0002 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0049 | 0.0277 | 0.0305 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0011 | 0.0041 | 0.0045 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0035 | 0.0799 |
Schistosoma mansoni | elf1 | 0.0011 | 0.0041 | 0.0045 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0122 | 0.0134 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0035 | 0.0799 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0005 | 0.0004 | 0.0004 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0298 | 0.0298 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0035 | 0.0038 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.0411 | 0.2525 | 0.2757 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0056 | 0.0318 | 0.035 |
Onchocerca volvulus | 0.0074 | 0.0434 | 1 | |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0161 | 0.0161 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0034 | 0.0037 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.0411 | 0.2525 | 0.2784 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0035 | 0.0035 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0349 | 0.2138 | 0.2358 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0011 | 0.0041 | 0.0045 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0028 | 0.003 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.023 | 0.0254 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0011 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.0235 | 0.0235 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0349 | 0.2138 | 0.2358 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0035 | 0.0038 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0108 | 0.0428 |
Toxoplasma gondii | hypothetical protein | 0.0056 | 0.0322 | 0.0355 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0034 | 0.0037 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0056 | 0.0318 | 0.0347 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0298 | 0.0298 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.009 | 0.0099 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.0411 | 0.2525 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0411 | 0.2525 | 0.2784 |
Onchocerca volvulus | 0.0005 | 0.0002 | 0.0042 | |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.0444 | 0.049 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0035 | 0.0035 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0035 | 0.0038 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0056 | 0.0318 | 0.0314 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0122 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0018 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Onchocerca volvulus | 0.001 | 0.0035 | 0.0799 | |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0122 | 0.0134 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0122 | 0.0134 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0931 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0002 | 0.0002 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0411 | 0.2525 | 0.2784 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0035 | 0.0799 |
Brugia malayi | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | ets-related | 0.0011 | 0.0041 | 0.0045 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Brugia malayi | tailless protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0035 | 0.0038 |
Leishmania major | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Toxoplasma gondii | propionate-CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0298 | 0.0328 |
Onchocerca volvulus | 0.0005 | 0.0002 | 0.0042 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | protein C ets 2 | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | ecdysone receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Brugia malayi | Inositol-1 | 0.0042 | 0.0235 | 0.0259 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | 0.0029 | 0.0151 | 0.3472 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0052 | 0.0057 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0034 | 0.0034 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0011 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0072 | 0.0079 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | hypothetical protein | 0.0042 | 0.023 | 0.0254 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0035 | 0.0038 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0103 | 0.0077 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0165 | 0.0997 | 0.11 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0151 | 0.0166 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.0235 | 0.0259 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0022 | 0.0108 | 0.0428 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0184 | 0.1113 | 0.1227 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.0208 | 0.0229 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0022 | 0.0108 | 0.0428 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.0411 | 0.2525 | 0.2782 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0298 | 0.0328 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0017 | 0.0017 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.1465 | 0.907 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | fli-1 protein | 0.0231 | 0.1405 | 0.1549 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0005 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | oxidoreductase | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0005 | 0.0006 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0074 | 0.0434 | 0.172 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0011 | 0.0041 | 0.0045 |
Mycobacterium ulcerans | hypothetical protein | 0.0184 | 0.1113 | 0.1227 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.0411 | 0.2525 | 0.2784 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0052 | 0.0206 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0005 | 0.0006 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | Muscleblind-like protein | 0.032 | 0.1962 | 0.2164 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.0997 | 0.11 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0017 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0122 | 0.0122 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | geminin | 0.0196 | 0.1188 | 0.1188 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.1465 | 0.907 | 1 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0022 | 0.0108 | 0.0108 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0011 | 0.0041 | 0.0041 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0082 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0011 | 0.0041 | 0.0041 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0035 | 0.0035 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Fli-1 protein | 0.0231 | 0.1405 | 0.1549 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.1465 | 0.907 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 0.0235 | 0.0259 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | ets-related | 0.0231 | 0.1405 | 0.1549 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0411 | 0.2525 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | nuclear receptor NHR-88 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.0235 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0004 | 0.0004 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | transcription factor E74 isoform | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0298 | 0.0328 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0011 | 0.0041 | 0.0045 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.0411 | 0.2525 | 0.2525 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0005 | 0.0004 | 0.0004 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0235 | 0.0259 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0151 | 0.0166 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.0411 | 0.2525 | 0.2525 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0022 | 0.0108 | 0.0119 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Entamoeba histolytica | recQ family DNA helicase | 0.0005 | 0.0004 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0035 | 0.0038 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | nuclear receptor NHR-67 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.023 | 0.0254 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.0411 | 0.2525 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | muscleblind protein 1 | 0.032 | 0.1962 | 0.1962 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.0444 | 0.049 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.0444 | 0.049 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.1465 | 0.907 | 1 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0035 | 0.0038 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0349 | 0.2138 | 0.2358 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0005 | 0.0005 |
Entamoeba histolytica | recQ family helicase, putative | 0.0005 | 0.0003 | 0.001 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0074 | 0.0434 | 0.172 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.0235 | 0.0259 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.1465 | 0.907 | 1 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0235 | 0.0259 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.0208 | 0.0822 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | ~ 0.001 M | In vitro inhibition of growth of L1210 mouse leukemic cells | ChEMBL. | 7328577 |
ILS (functional) | = 1 % | Increase in life span of tumor L1210 leukemic mice 1-5 days after 200 mg/kg of the compound administered | ChEMBL. | 7328577 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.