Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | microtubule associated protein 2 | 0.0748 | 0.8453 | 0.8285 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0311 | 0.3115 | 0.8719 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 0.1115 | 0.0148 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0348 | 0.3567 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0311 | 0.3115 | 0.8719 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0311 | 0.3115 | 0.8719 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0311 | 0.3115 | 0.2366 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 0.1115 | 0.0148 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0748 | 0.8453 | 0.8285 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0311 | 0.3115 | 0.2366 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0311 | 0.3115 | 0.8719 |
Echinococcus multilocularis | tumor protein p63 | 0.0351 | 0.3605 | 0.291 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0311 | 0.3115 | 0.8719 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0348 | 0.3567 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.8719 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0348 | 0.3567 | 1 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0311 | 0.3115 | 0.2366 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0147 | 0.1115 | 0.0148 |
Toxoplasma gondii | ran binding protein | 0.0311 | 0.3115 | 0.3115 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0311 | 0.3115 | 0.7984 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0311 | 0.3115 | 0.8719 |
Schistosoma mansoni | zinc finger protein | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0311 | 0.3115 | 0.8719 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Schistosoma mansoni | RNA binding protein | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.1327 | 0.3643 |
Schistosoma mansoni | hypothetical protein | 0.0311 | 0.3115 | 0.2366 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0311 | 0.3115 | 0.2366 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.2172 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.8719 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0311 | 0.3115 | 0.3115 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0311 | 0.3115 | 0.7984 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0748 | 0.8453 | 0.8285 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0311 | 0.3115 | 0.2366 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.8719 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0348 | 0.3567 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0183 | 0.1554 | 0.5 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0311 | 0.3115 | 0.2366 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Schistosoma mansoni | fusion | 0.0311 | 0.3115 | 0.2366 |
Brugia malayi | YY1-associated factor 2 | 0.0311 | 0.3115 | 0.2438 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0311 | 0.3115 | 0.2366 |
Echinococcus granulosus | tumor protein p63 | 0.0351 | 0.3605 | 0.291 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.