Detailed information for compound 1297275

Basic information

Technical information
  • TDR Targets ID: 1297275
  • Name: 2,5-Bis(3,4,5-trimethoxyphenyl)-1,3,4-oxadiaz ole
  • MW: 402.398 | Formula: C20H22N2O7
  • H donors: 0 H acceptors: 2 LogP: 2.9 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(cc(c1OC)OC)c1nnc(o1)c1cc(OC)c(c(c1)OC)OC
  • InChi: 1S/C20H22N2O7/c1-23-13-7-11(8-14(24-2)17(13)27-5)19-21-22-20(29-19)12-9-15(25-3)18(28-6)16(10-12)26-4/h7-10H,1-6H3
  • InChiKey: PJMJPGFUGZBTAE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 23288-95-1
  • MLS000527344
  • 2,5-Bis-(3,4,5-trimethoxy-phenyl)-[1,3,4]oxadiazole
  • BAS 03027873
  • 1,3,4-OXADIAZOLE, 2,5-BIS(3,4,5-TRIMETHOXYPHENYL)-
  • 2,5-Bis(3,4,5-trimetossifenilico)-1,3,4-ossadiazoli [Italian]
  • BRN 1050733
  • ZINC02015183
  • AF-399/40768929
  • SMR000117818
  • ST5046244

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0003 0.0043
Giardia lamblia Cathepsin L-like protease 0.0027 0.0009 0.0431
Schistosoma mansoni tar DNA-binding protein 0.0957 0.0681 0.0681
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0028 0.0704
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0021 0.0517
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.0633
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0046 0.0023 0.0023
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0027 0.0009 0.0161
Schistosoma mansoni phosphoglucomutase 0.0022 0.0006 0.0006
Echinococcus granulosus nibrin 0.0019 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Plasmodium vivax unspecified product 0.0027 0.0009 0.0161
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0002 0.0002
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0556 0.0391 1
Brugia malayi Cathepsin L-like precursor 0.0123 0.0078 0.0985
Brugia malayi Cathepsin L-like precursor 0.0123 0.0078 0.0985
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.0058 0.0133
Plasmodium falciparum serine repeat antigen 6 0.0027 0.0009 0.0161
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0003 0.0069
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0002 0.0002
Echinococcus granulosus phd:f box containing protein 0.0019 0.0003 0.0003
Brugia malayi larval opioid receptor 0.0017 0.0002 0.0023
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0556 0.0391 0.0391
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.0041 0.0041
Schistosoma mansoni intermediate filament proteins 0.0126 0.008 0.008
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.0196 0.0196
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0001 0.0005
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0027 0.0009 0.0161
Brugia malayi Serotonin receptor 0.0017 0.0002 0.0023
Schistosoma mansoni phosphoglucomutase 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0007 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0009 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.0039 0.0018 0.0438
Brugia malayi mbt repeat family protein 0.0058 0.0031 0.0394
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0021 0.0517
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0034 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0005 0.0067
Echinococcus multilocularis cysteine protease 0.0123 0.0078 0.0078
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0041 0.0517
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0016 0.0001 0.0017
Echinococcus granulosus sterol regulatory element binding protein 0.0092 0.0056 0.0056
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0033 0.0837
Trypanosoma cruzi prolyl endopeptidase 0.0021 0.0005 0.012
Brugia malayi Pre-SET motif family protein 0.0095 0.0058 0.0732
Brugia malayi MH2 domain containing protein 0.0076 0.0045 0.0561
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0002 0.0002
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0031 0.0031
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0085 0.0051 0.0116
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0003 0.0003
Trypanosoma cruzi oligopeptidase b 0.0021 0.0005 0.012
Onchocerca volvulus 0.0017 0.0002 0.0013
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0022 0.0395
Loa Loa (eye worm) hypothetical protein 0.006 0.0033 0.0417
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0033 0.0073
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0046 0.0023 0.0023
Brugia malayi beta-lactamase 0.0071 0.0041 0.0517
Schistosoma mansoni hypothetical protein 0.0355 0.0246 0.0246
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0003 0.0043
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0002 0.0002
Leishmania major cysteine peptidase A (CPA) 0.0123 0.0078 0.1991
Echinococcus granulosus fmrfamide receptor 0.0017 0.0002 0.0002
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0021 0.0005 0.012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0046 0.0023 0.0284
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0002 0.0023
Brugia malayi Cathepsin L-like cysteine proteinase 0.0084 0.005 0.0634
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0033 0.0013 0.0168
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0033 0.0837
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0009 0.0158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0088 0.0088
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0041 0.0099
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0028 0.0704
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.0004 0.0101
Brugia malayi MH2 domain containing protein 0.1116 0.0796 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0088 0.0088
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0397 0.0277 0.0277
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable reductase 0.0193 0.0129 0.0308
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0012 0.027
Toxoplasma gondii hypothetical protein 0.0033 0.0013 0.0309
Toxoplasma gondii hypothetical protein 0.0048 0.0025 0.06
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0006 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0003 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0003 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0115 0.2157
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0002 0.0002
Brugia malayi cathepsin L-like cysteine proteinase 0.0027 0.0009 0.0119
Echinococcus granulosus GPCR family 2 0.0221 0.0149 0.0149
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0028 0.0704
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0123 0.0078 0.1468
Echinococcus granulosus prolyl endopeptidase 0.0021 0.0005 0.0005
Brugia malayi glutathione reductase 0.0085 0.0051 0.064
Brugia malayi cathepsin L-like precursor 0.0084 0.005 0.0634
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0003 0.0069
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0058 0.0032 0.0032
Toxoplasma gondii FATC domain-containing protein 0.0028 0.001 0.0225
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0002 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0033 0.0837
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0011 0.0267
Brugia malayi hypothetical protein 0.0069 0.004 0.0501
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0222 0.015 0.2828
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0002 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0011 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0066 0.0037 0.0689
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Trypanosoma cruzi ribonuclease H1, putative 0.0022 0.0006 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.0158
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0556 0.0391 0.0391
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0221 0.0149 0.0149
Schistosoma mansoni RAR-like nuclear receptor 0.0046 0.0023 0.0023
Plasmodium vivax vivapain-2 0.0123 0.0078 0.1935
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0021 0.0005 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.1116 0.0796 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0009 0.0158
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.0633
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0118
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0041 0.0092
Echinococcus multilocularis Niemann Pick C1 protein 0.0307 0.0212 0.0212
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0041 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0118
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0088 0.0088
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.025 0.017 0.214
Entamoeba histolytica hypothetical protein 0.0067 0.0038 0.1923
Plasmodium falciparum pantothenate kinase 2, putative 0.0028 0.001 0.0173
Brugia malayi hypothetical protein 0.0024 0.0007 0.009
Loa Loa (eye worm) fibroinase 0.0123 0.0078 0.0984
Leishmania major cathepsin L-like protease 0.0179 0.0119 0.3041
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0004 0.0101
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0012 0.0287
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus granulosus dna polymerase eta 0.006 0.0033 0.0033
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0034 0.0075
Onchocerca volvulus 0.0017 0.0002 0.0013
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0028 0.0028
Schistosoma mansoni cpg binding protein 0.0064 0.0036 0.0036
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0022 0.0052
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0031 0.0031
Echinococcus multilocularis serine protein kinase ATM 0.0028 0.001 0.001
Brugia malayi G protein-coupled receptor 0.0017 0.0002 0.0023
Giardia lamblia Cysteine protease 0.0027 0.0009 0.0431
Loa Loa (eye worm) hypothetical protein 0.0058 0.0031 0.0393
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.005 0.2554
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0043
Entamoeba histolytica prolyl oligopeptidase family protein 0.0021 0.0005 0.0209
Giardia lamblia GTOR 0.002 0.0004 0.0171
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramyl pentapeptide synthase 0.5672 0.4088 1
Giardia lamblia Cathepsin B precursor 0.0027 0.0009 0.0431
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0041 0.0092
Trypanosoma cruzi cysteine proteinase, putative 0.0066 0.0037 0.0944
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0004 0.0101
Brugia malayi prolyl oligopeptidase family protein 0.0134 0.0087 0.109
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0046 0.0023 0.0285
Echinococcus multilocularis cysteine protease 0.0123 0.0078 0.0078
Loa Loa (eye worm) pantothenate kinase 0.0066 0.0038 0.0472
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0002 0.0002
Leishmania major DNA polymerase kappa, putative 0.0019 0.0003 0.0069
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0027 0.0009 0.0161
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0002 0.0022
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0021 0.0005 0.0005
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0003 0.0075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0022 0.0548
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0033 0.0013 0.0013
Echinococcus granulosus g protein coupled receptor 0.0017 0.0002 0.0002
Brugia malayi Serine carboxypeptidase S28 family protein 0.0016 0.0001 0.0015
Brugia malayi steroid hormone receptor 0.0046 0.0023 0.0285
Trypanosoma cruzi cruzipain precursor, putative 0.0179 0.0119 0.3041
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0681 0.0482 0.6054
Echinococcus granulosus sex peptide receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0075
Trichomonas vaginalis set domain proteins, putative 0.0744 0.0527 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0009 0.0158
Giardia lamblia Cysteine protease 0.0027 0.0009 0.0431
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0002 0.0002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0052 0.0027 0.068
Mycobacterium tuberculosis Conserved protein 0.0071 0.0041 0.0092
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0516
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0023 0.0023
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0002 0.0002
Schistosoma mansoni Smad4 0.0076 0.0045 0.0045
Giardia lamblia Cathepsin B precursor 0.0085 0.0051 0.2599
Onchocerca volvulus 0.0084 0.005 0.0937
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Loa Loa (eye worm) latrophilin receptor protein 2 0.0221 0.0149 0.1875
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.0005 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0221 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Brugia malayi nuclear hormone receptor 0.0046 0.0023 0.0285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0058 0.0058
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0047 0.0024 0.1165
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0002 0.0023
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0002 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Echinococcus multilocularis serotonin receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0076 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0082 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0046 0.0023 0.0285
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0002 0.0002
Echinococcus multilocularis importin subunit beta 1 0.0064 0.0036 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0028 0.0511
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0698 0.0494 0.6208
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Giardia lamblia Cysteine protease 0.0027 0.0009 0.0431
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0064
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3158 0.2272 0.2272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0046 0.0023 0.0284
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.0004 0.0101
Trypanosoma brucei prolyl endopeptidase 0.0021 0.0005 0.012
Schistosoma mansoni cathepsin B (C01 family) 0.0027 0.0009 0.0009
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0022 0.0006 0.0005
Echinococcus multilocularis Ankyrin 0.0014 0.0000087348 0.0000087348
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.018 0.012 0.2262
Entamoeba histolytica cysteine protease, putative 0.0027 0.0009 0.0431
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0088 0.0088
Mycobacterium leprae Probable lipase LipE 0.0071 0.0041 0.0092
Brugia malayi ecdysone receptor 0.0022 0.0005 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0005 0.012
Entamoeba histolytica cysteine proteinase, putative 0.0123 0.0078 0.4001
Schistosoma mansoni Smad4 0.0034 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0033 0.0837
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Brugia malayi G-protein coupled receptor 0.0017 0.0002 0.0023
Echinococcus multilocularis thioredoxin glutathione reductase 0.0085 0.0051 0.0051
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0215 0.0145 0.0346
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0009 0.0118
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0027 0.0671
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0002 0.0002
Echinococcus granulosus g protein coupled receptor 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0221 0.0149 0.0149
Brugia malayi prolyl oligopeptidase family protein 0.018 0.012 0.151
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramyl tripeptide synthase 0.1676 0.1201 0.2931
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0088 0.0088
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0052 0.0027 0.0493
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0019 0.0909
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0011 0.0267
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0007 0.009
Echinococcus granulosus TGF beta signal transducer SmadC 0.0076 0.0045 0.0045
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Giardia lamblia Alanyl dipeptidyl peptidase 0.0021 0.0005 0.0209
Schistosoma mansoni tar DNA-binding protein 0.0957 0.0681 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0085 0.0051 0.0953
Echinococcus multilocularis cpg binding protein 0.0064 0.0036 0.0036
Plasmodium vivax vivapain-2 0.0123 0.0078 0.1935
Chlamydia trachomatis UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 0.1676 0.1201 0.2931
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0003 0.0043
Schistosoma mansoni cathepsin s 0.0039 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0046 0.0023 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0019 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0001 0.0005
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0027 0.0009 0.0431
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0004 0.0101
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0065 0.0037 0.0458
Loa Loa (eye worm) hypothetical protein 0.0058 0.0032 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.0158
Trypanosoma cruzi cruzipain precursor, putative 0.0039 0.0018 0.0438
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0024 0.0007 0.0088
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.001 0.0125
Brugia malayi MH1 domain containing protein 0.0042 0.002 0.0253
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0003 0.0043
Plasmodium falciparum serine repeat antigen 8 0.0027 0.0009 0.0161
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0123 0.0079 0.0989
Plasmodium vivax unspecified product 0.0039 0.0018 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Leishmania major pantothenate kinase subunit, putative 0.0071 0.0041 0.1031
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0027 0.0009 0.0161
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0123 0.0078 0.0985
Schistosoma mansoni cathepsin S (C01 family) 0.0027 0.0009 0.0009
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0003 0.0059
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Echinococcus granulosus FTZ F1 alpha 0.0046 0.0023 0.0023
Loa Loa (eye worm) thioredoxin reductase 0.0085 0.0051 0.0639
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0012 0.0287
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0021 0.0005 0.0004
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Echinococcus multilocularis cathepsin L 0.0027 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Brugia malayi Thioredoxin reductase 0.0085 0.0051 0.064
Loa Loa (eye worm) MBCTL1 0.0066 0.0037 0.0465
Brugia malayi beta-lactamase family protein 0.0071 0.0041 0.0517
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Echinococcus granulosus allatostatin A receptor 0.0017 0.0002 0.0002
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0021 0.0005 0.012
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0041 0.0041
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0029 0.0011 0.0018
Trichomonas vaginalis pantothenate kinase, putative 0.0066 0.0038 0.0693
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0134 0.0087 0.2205
Brugia malayi RNase H family protein 0.0022 0.0006 0.0069
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.0206 0.525
Schistosoma mansoni topbp1 0.0019 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0027 0.0009 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Giardia lamblia Cathepsin L precursor 0.0027 0.0009 0.0431
Onchocerca volvulus Protein ultraspiracle homolog 0.0046 0.0023 0.0409
Echinococcus granulosus GTP binding nuclear protein Ran 0.0047 0.0024 0.0024
Giardia lamblia Cathepsin L precursor 0.0027 0.0009 0.0431
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0058 0.1455
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0046 0.0023 0.0023
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0003 0.0119
Entamoeba histolytica prolyl oligopeptidase family protein 0.0021 0.0005 0.0209
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0019 0.0399
Toxoplasma gondii pantothenate kinase 0.0028 0.001 0.0225
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.0005 0.0066
Echinococcus granulosus Smad4 0.0076 0.0045 0.0045
Plasmodium falciparum cysteine proteinase falcipain 1 0.0066 0.0037 0.088
Entamoeba histolytica hypothetical protein 0.0052 0.0027 0.1344
Entamoeba histolytica prolyl oligopeptidase family protein 0.0021 0.0005 0.0209
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Entamoeba histolytica hypothetical protein 0.0067 0.0038 0.1923
Leishmania major importin beta-1 subunit, putative 0.0052 0.0027 0.068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0028 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0179 0.0119 0.3041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0009 0.0158
Plasmodium falciparum peptidase, putative 0.0021 0.0005 0.0051
Echinococcus granulosus cathepsin l1 0.0123 0.0078 0.0078
Echinococcus multilocularis neuropeptide receptor A26 0.0017 0.0002 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0011 0.0198
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0047 0.0024 0.0297
Trichomonas vaginalis ribonuclease H1, putative 0.0022 0.0006 0.0083
Brugia malayi CHE-14 protein 0.0092 0.0056 0.0709
Brugia malayi Steroid receptor seven-up type 2 0.0046 0.0023 0.0285
Echinococcus multilocularis protein dispatched 1 0.0105 0.0066 0.0066
Leishmania major DNA polymerase kappa, putative 0.006 0.0033 0.0837
Trypanosoma cruzi ribonuclease H1, putative 0.0022 0.0006 0.0128
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0005 0.0051
Onchocerca volvulus 0.0017 0.0002 0.0013
Brugia malayi mothers against decapentaplegic homolog 3 0.0034 0.0014 0.0179
Loa Loa (eye worm) MH2 domain-containing protein 0.0076 0.0045 0.056
Echinococcus granulosus cathepsin L cysteine proteinase 0.0123 0.0078 0.0078
Plasmodium falciparum cysteine proteinase falcipain 3 0.0123 0.0078 0.1935
Echinococcus multilocularis cathepsin b 0.0214 0.0145 0.0145
Brugia malayi MH1 domain containing protein 0.0076 0.0045 0.0561
Echinococcus multilocularis dna polymerase eta 0.006 0.0033 0.0033
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0011 0.0011
Echinococcus multilocularis tar DNA binding protein 0.0957 0.0681 0.0681
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0094 0.0094
Echinococcus multilocularis geminin 0.0682 0.0483 0.0483
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0012 0.0219
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0003 0.0057
Echinococcus granulosus cathepsin b 0.0214 0.0145 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0017 0.0309
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0011 0.0506
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0037 0.0944
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0028 0.001 0.001
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0002 0.0002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0033 0.0837
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Giardia lamblia Encystation-specific protease 0.0027 0.0009 0.0431
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0047 0.0024 0.0296
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0011 0.0186
Echinococcus multilocularis snurportin 1 0.0681 0.0482 0.0482
Giardia lamblia Cathepsin B precursor 0.0027 0.0009 0.0431
Echinococcus granulosus ecdysone induced protein 78C 0.0046 0.0023 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0957 0.0681 0.0681
Brugia malayi hypothetical protein 0.003 0.0012 0.0147
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0021 0.0005 0.0005
Loa Loa (eye worm) prolyl oligopeptidase 0.0021 0.0005 0.0064
Loa Loa (eye worm) hypothetical protein 0.0126 0.008 0.101
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0041 0.076
Brugia malayi Serotonin receptor 0.0017 0.0002 0.0023
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.009 0.0211
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0041 0.0041
Leishmania major cathepsin L-like protease 0.0123 0.0078 0.1991
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0041 0.0092
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0037 0.0466
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0021 0.0005 0.0209
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0037 0.1878
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0002 0.0002
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0003 0.0003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0215 0.0145 0.7459
Brugia malayi Pre-SET motif family protein 0.0654 0.0462 0.5805
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0039 0.0018 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0028 0.0511
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0221 0.0149 0.0149
Toxoplasma gondii exonuclease III APE 0.0022 0.0005 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.0196 0.0196
Brugia malayi Cathepsin L-like precursor 0.0123 0.0078 0.0985
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0002 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0005 0.0005
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0002 0.0022
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0011 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.002 0.0501
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0033 0.0033
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0088 0.0088
Giardia lamblia Pantothenate kinase 4 0.0066 0.0038 0.189
Brugia malayi MH2 domain containing protein 0.0076 0.0045 0.0561
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Brugia malayi prolyl oligopeptidase family protein 0.0021 0.0005 0.0065
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0004 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trypanosoma brucei pantothenate kinase subunit, putative 0.0066 0.0038 0.0949
Brugia malayi Inositol-1 0.0045 0.0022 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0041 0.1039
Onchocerca volvulus 0.0017 0.0002 0.0013
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0069
Treponema pallidum UDP-N-acetylmuramate--L-alanine ligase 0.3285 0.2363 0.5777
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0058 0.0058
Echinococcus granulosus tumor protein p63 0.2344 0.1684 0.1684
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0004 0.0101
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Mycobacterium leprae ProbableUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 0.5672 0.4088 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0002 0.0022
Brugia malayi GnHR receptor homolog 0.0017 0.0002 0.0023
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0123 0.0078 0.1935
Schistosoma mansoni hypothetical protein 0.0089 0.0054 0.0054
Trypanosoma brucei cysteine peptidase C (CPC) 0.0085 0.0051 0.1299
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.1676 0.1201 0.2931
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0005 0.0078
Brugia malayi hypothetical protein 0.002 0.0004 0.0049
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0005 0.0222
Brugia malayi AKH receptor 0.0017 0.0002 0.0023
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0022 0.1077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0046 0.0023 0.0284
Schistosoma mansoni zinc finger protein 0.0022 0.0005 0.0005
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0021 0.0005 0.0103
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0037 0.0037
Brugia malayi hypothetical protein 0.0019 0.0003 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.0104 0.0245
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0037 0.1878
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0214 0.0145 0.0145
Loa Loa (eye worm) acetyltransferase 0.0149 0.0097 0.1221
Entamoeba histolytica cysteine protease, putative 0.0027 0.0009 0.0431
Onchocerca volvulus 0.0017 0.0002 0.0013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0003 0.0074
Brugia malayi conserved hypotetical protein 0.0022 0.0005 0.0066
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0021 0.0005 0.012
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0033 0.0837
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0046 0.0023 0.0284
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0654 0.0462 0.5805
Brugia malayi hypothetical protein 0.0067 0.0038 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0009 0.0158
Trypanosoma brucei ingi protein (ORF1) 0.0024 0.0007 0.0162
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0231 0.0157 0.0157
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0021 0.0005 0.012
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0058 0.1455
Toxoplasma gondii fumble protein 0.0066 0.0038 0.0934
Brugia malayi RNase H family protein 0.0022 0.0006 0.0069
Loa Loa (eye worm) hypothetical protein 0.0123 0.0078 0.0984
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.0166 0.2088
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0085 0.0051 0.1299
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0004 0.0101
Trypanosoma brucei importin beta-1 subunit, putative 0.0064 0.0036 0.0903
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0024 0.0007 0.0007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0957 0.0681 0.856
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0028 0.0028
Brugia malayi Probable ClpP-like protease 0.0094 0.0058 0.0728
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0011 0.025
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0091
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0002 0.0023
Schistosoma mansoni smad1 5 8 and 0.0076 0.0045 0.0045
Brugia malayi Niemann-Pick C1 protein precursor 0.0215 0.0145 0.1823
Onchocerca volvulus 0.0123 0.0078 0.1468
Brugia malayi hypothetical protein 0.0286 0.0196 0.2464
Onchocerca volvulus 0.0017 0.0002 0.0013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.0088 0.1105
Loa Loa (eye worm) MH1 domain-containing protein 0.0076 0.0045 0.056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0215 0.0145 0.0346
Giardia lamblia Cathepsin L-like protease 0.0027 0.0009 0.0431
Trypanosoma cruzi major cysteine proteinase, putative 0.0027 0.0009 0.023
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0009 0.0119
Echinococcus granulosus Dipeptidyl peptidase 9 0.0134 0.0087 0.0087
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.006 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0089 0.0054 0.0054
Echinococcus multilocularis cathepsin b 0.0214 0.0145 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.002 0.0501
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0005 0.0005
Echinococcus multilocularis pantothenate kinase 4 0.0066 0.0038 0.0038
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0027 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Schistosoma mansoni pantothenate kinase 0.0066 0.0038 0.0038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0002 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0064 0.0036 0.0903
Echinococcus granulosus cathepsin L 0.0027 0.0009 0.0009
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.009 0.021
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0032 0.04
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0194 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0033 0.1662
Echinococcus granulosus mothers against decapentaplegic 2 0.0034 0.0014 0.0014
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0022 0.0022
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0041 0.076
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0031 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0027 0.0009 0.0158
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0123 0.0078 0.1468
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Loa Loa (eye worm) intermediate filament protein 0.0126 0.008 0.101
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Mycobacterium tuberculosis Probable peptidase 0.0021 0.0005 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0023 0.0023
Onchocerca volvulus 0.0017 0.0002 0.0013
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0047 0.0024 0.0592
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0027 0.0009 0.0118
Trypanosoma brucei protein kinase, putative 0.0053 0.0028 0.0704
Brugia malayi RE15519p 0.0017 0.0002 0.0023
Brugia malayi intermediate filament protein 0.0126 0.008 0.1011
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0037 0.0037
Mycobacterium tuberculosis Possible ligase 0.0556 0.0391 0.095
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0556 0.0391 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0024 0.0007 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0041 0.076
Plasmodium vivax vivapain-3 0.0066 0.0037 0.088
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0004 0.0101
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0002 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0123 0.0078 0.4001
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0028 0.0689
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0012 0.0287
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0027 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.002 0.0492
Mycobacterium ulcerans hypothetical protein 0.0071 0.0041 0.0099
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.0005 0.0077
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0003 0.0075
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0028 0.0704
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.0194 0.0467
Trichomonas vaginalis ran, putative 0.0047 0.0024 0.0427
Leishmania major cathepsin L-like protease 0.0179 0.0119 0.3041
Entamoeba histolytica Ran family GTPase 0.0047 0.0024 0.1165
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0011 0.0011
Schistosoma mansoni cellular tumor antigen P53 0.0343 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0066 0.0037 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0023 0.0285
Brugia malayi MH1 domain containing protein 0.0076 0.0045 0.0561
Plasmodium vivax serine-repeat antigen (SERA) 0.0027 0.0009 0.0161
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0034 0.0034
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0007 0.0162
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0013 0.0024
Schistosoma mansoni nuclear receptor 0.0022 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.017 0.3216
Trypanosoma brucei trypanothione reductase 0.0085 0.0051 0.129
Echinococcus multilocularis ribonuclease H1 0.0022 0.0006 0.0006
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0556 0.0391 0.7422
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0009 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0046 0.0023 0.0284
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0214 0.0145 0.0145
Chlamydia trachomatis UDP-N-acetylmuramoylalanine--D-glutamate ligase 0.1676 0.1201 0.2931
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0002 0.0002
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0003 0.0057
Schistosoma mansoni survival motor neuron protein 0.0058 0.0032 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0005 0.0081
Leishmania major DNA polymerase eta, putative 0.006 0.0033 0.0837
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0041 0.076
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0022 0.0548
Brugia malayi prolyl oligopeptidase family protein 0.0021 0.0005 0.0065
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0002 0.0022
Schistosoma mansoni hypothetical protein 0.0089 0.0054 0.0054
Echinococcus granulosus Protein patched homolog 1 0.0092 0.0056 0.0056
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0003 0.0069
Trichomonas vaginalis pantothenate kinase, putative 0.0066 0.0038 0.0693
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0009 0.0009
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0047 0.0024 0.0526
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0034 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Echinococcus multilocularis tumor protein p63 0.2344 0.1684 0.1684
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Brugia malayi Cytochrome P450 family protein 0.0015 0.0001 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0014
Onchocerca volvulus 0.0123 0.0078 0.1468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Plasmodium vivax serine-repeat antigen (SERA) 0.0027 0.0009 0.0161
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0004 0.0101
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0058 0.0058
Brugia malayi Dopamine receptor protein 2 0.0017 0.0002 0.0023
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0215 0.0145 0.0346
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0021 0.0005 0.0209
Onchocerca volvulus 0.0058 0.0031 0.0574
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0002 0.0023
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0003 0.0069
Echinococcus granulosus cathepsin b 0.0214 0.0145 0.0145
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0516
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0027 0.0009 0.0161
Leishmania major GTP-binding protein, putative 0.0047 0.0024 0.0592
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0134 0.0087 0.0087
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0022 0.0548
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramoylalanine-D-glutamate ligase 0.0556 0.0391 0.095
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0455 0.0318 0.077
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Schistosoma mansoni hypothetical protein 0.0221 0.0149 0.0149
Onchocerca volvulus Cathepsin L homolog 0.0123 0.0078 0.1468
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0013 0.0024
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0061 0.0033 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi RNA binding protein 0.0957 0.0681 0.856
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0133
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0003 0.0075
Treponema pallidum ribonuclease H (rnhA) 0.0022 0.0006 0.0005
Entamoeba histolytica cysteine proteinase 1, putative 0.0066 0.0037 0.1878
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0023 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0011 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.1676 0.1201 0.2931
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0009 0.0119
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.0005 0.0005
Echinococcus granulosus Ankyrin 0.0014 0.0000087348 0.0000087348
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Trypanosoma cruzi cysteine proteinase, putative 0.0066 0.0037 0.0944
Loa Loa (eye worm) hypothetical protein 0.0221 0.0149 0.1875
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.0206 0.525
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0134 0.0087 0.2205
Mycobacterium ulcerans UDP-N-acetylmuramate--L-alanine ligase 0.3285 0.2363 0.578
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Entamoeba histolytica hypothetical protein 0.0019 0.0003 0.0118
Leishmania major cathepsin L-like protease 0.0123 0.0078 0.1991
Mycobacterium leprae possible ligase 0.0556 0.0391 0.095
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus granulosus dna polymerase kappa 0.006 0.0033 0.0033
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0011 0.0025
Brugia malayi jmjC domain containing protein 0.0019 0.0003 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0012 0.0219
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0066 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0682 0.0483 0.0483
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Onchocerca volvulus 0.0027 0.0009 0.0158
Plasmodium vivax unspecified product 0.0066 0.0037 0.088
Plasmodium falciparum serine repeat antigen 3 0.0027 0.0009 0.0161
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0055 0.0055
Onchocerca volvulus 0.0126 0.008 0.1507
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Toxoplasma gondii cathepsin B 0.0085 0.0051 0.1285
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0037 0.0037
Brugia malayi polk-prov protein 0.0019 0.0003 0.0041
Echinococcus granulosus nmda type glutamate receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0014
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0003 0.0053
Mycobacterium tuberculosis Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 0.5672 0.4088 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0002 0.0002
Echinococcus multilocularis sterol regulatory element binding protein 0.0092 0.0056 0.0056
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0002 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0009 0.0158
Schistosoma mansoni pantothenate kinase 0.0066 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0123 0.0078 0.1991
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0009 0.0009
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0037 0.0037
Brugia malayi fibroinase precursor 0.0027 0.0009 0.0119
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0002 0.0002
Toxoplasma gondii cathepsin CPC1 0.0027 0.0009 0.0213
Schistosoma mansoni steroid hormone receptor ad4bp 0.0046 0.0023 0.0023
Echinococcus multilocularis neuropeptide s receptor 0.0017 0.0002 0.0002
Trypanosoma brucei unspecified product 0.0042 0.002 0.0492
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0022 0.0005 0.0005
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0134 0.0087 0.2205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0037 0.0944
Brugia malayi Dopamine receptor 0.0017 0.0002 0.0023
Leishmania major hypothetical protein, conserved 0.0071 0.0041 0.1039
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0002 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0041 0.1039
Schistosoma mansoni DNA ligase IV 0.0019 0.0003 0.0003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.0041 0.0041
Loa Loa (eye worm) RNA binding protein 0.0957 0.0681 0.856
Echinococcus multilocularis Niemann Pick C1 protein 0.0215 0.0145 0.0145
Entamoeba histolytica pantothenate kinase 1, putative 0.0066 0.0038 0.189
Loa Loa (eye worm) nuclear factor I 0.0042 0.002 0.0251
Giardia lamblia Cathepsin L precursor 0.0027 0.0009 0.0431
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0052 0.0027 0.0493
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Trypanosoma brucei RNA helicase, putative 0.0082 0.0049 0.1238
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.018 0.012 0.012
Brugia malayi neuropeptide F receptor 0.0017 0.0002 0.0023
Schistosoma mansoni lamin 0.0126 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Echinococcus multilocularis Smad4 0.0076 0.0045 0.0045
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0033 0.0033
Onchocerca volvulus 0.0071 0.0041 0.076
Toxoplasma gondii preprocathepsin c precursor, putative 0.0027 0.0009 0.0213
Loa Loa (eye worm) hypothetical protein 0.0222 0.015 0.1883
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0011 0.0137
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0002 0.0002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0047 0.0024 0.0592
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Schistosoma mansoni topbp1 0.0019 0.0003 0.0003
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0004 0.0101
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0041 0.0092
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Mycobacterium ulcerans UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 0.5672 0.4088 1
Trypanosoma brucei prolyl oligopeptidase, putative 0.0021 0.0005 0.012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.0108 0.2035
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0003 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0041 0.0976
Echinococcus granulosus thioredoxin glutathione reductase 0.0085 0.0051 0.0051
Plasmodium falciparum serine repeat antigen 4 0.0027 0.0009 0.0161
Echinococcus granulosus lamin dm0 0.0126 0.008 0.008
Entamoeba histolytica cysteine protease, putative 0.0123 0.0078 0.4001
Schistosoma mansoni adenoreceptor 0.0017 0.0002 0.0002
Giardia lamblia Hypothetical protein 0.0027 0.0009 0.0431
Echinococcus multilocularis lamin 0.0126 0.008 0.008
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Echinococcus multilocularis acylamino acid releasing enzyme 0.0021 0.0005 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0123 0.0078 0.0078
Brugia malayi MH1 domain containing protein 0.0042 0.002 0.0253
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0041 0.0516
Plasmodium falciparum pantothenate kinase 1, putative 0.0066 0.0038 0.0886
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Onchocerca volvulus 0.0071 0.0041 0.076
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus multilocularis sex peptide receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0077
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0058
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.018 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Giardia lamblia DINP protein human, muc B family 0.006 0.0033 0.1662
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.0194 1
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0556 0.0391 0.0391
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0221 0.0149 0.0149
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0004 0.0102
Onchocerca volvulus 0.0017 0.0002 0.0013
Brugia malayi Cathepsin L-like precursor 0.0123 0.0078 0.0985
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0027 0.0009 0.0009
Mycobacterium ulcerans beta-lactamase 0.0071 0.0041 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0027 0.0009 0.0158
Onchocerca volvulus Ribonuclease H1 homolog 0.0022 0.0006 0.0083
Onchocerca volvulus 0.0019 0.0003 0.0043
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0033 0.0837
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.025 0.017 0.214
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0033 0.061
Schistosoma mansoni biogenic amine receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Brugia malayi hypothetical protein 0.0019 0.0003 0.0043
Brugia malayi jmjC domain containing protein 0.0074 0.0044 0.0547
Brugia malayi Cathepsin L-like precursor 0.0084 0.005 0.0634
Trypanosoma cruzi cysteine peptidase, putative 0.0179 0.0119 0.3041
Brugia malayi Cathepsin L-like precursor 0.0039 0.0018 0.0222
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0005 0.0126
Brugia malayi Cytochrome P450 family protein 0.0015 0.0001 0.0006
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0028 0.1394
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0004 0.0171
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0004 0.0084
Echinococcus granulosus intermediate filament protein 0.0126 0.008 0.008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0067 0.0038 0.0038
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0028 0.0704
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0141 0.0091 0.2327
Schistosoma mansoni Smad4 0.0034 0.0014 0.0014
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0005 0.0209
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.0005 0.0005
Brugia malayi Smad1 0.0076 0.0045 0.0561
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0007 0.0169
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0005 0.0005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0041 0.0092
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.0005 0.0066
Schistosoma mansoni tar DNA-binding protein 0.0957 0.0681 0.0681
Trypanosoma brucei ribonuclease H1 0.0022 0.0006 0.0128
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0012 0.0207
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0066 0.0037 0.0689
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0005 0.0005
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0004 0.0102
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0076 0.0045 0.0045
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0009 0.0009
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0123 0.0078 0.1468
Echinococcus multilocularis GPCR, family 2 0.0221 0.0149 0.0149
Treponema pallidum UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (murF) 0.5672 0.4088 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0002 0.0002
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0005 0.0066
Trypanosoma cruzi major cysteine proteinase, putative 0.0084 0.0051 0.128
Brugia malayi Calcitonin receptor-like protein seb-1 0.0698 0.0494 0.6208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0118
Schistosoma mansoni hypothetical protein 0.0221 0.0149 0.0149
Brugia malayi cytoplasmic intermediate filament protein 0.0067 0.0038 0.0481
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0046 0.0023 0.0023
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0027 0.0009 0.0431
Loa Loa (eye worm) cathepsin B 0.0085 0.0051 0.0644
Echinococcus granulosus g protein coupled receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0039 0.0018 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0043
Giardia lamblia Cysteine protease 0.0027 0.0009 0.0431
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0009 0.0158
Loa Loa (eye worm) hypothetical protein 0.0092 0.0056 0.0708
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0027 0.0009 0.0158
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0146
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0003 0.0003
Echinococcus granulosus cathepsin L cysteine protease 0.0066 0.0037 0.0037
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0006 0.0006
Onchocerca volvulus 0.0058 0.0032 0.0583
Echinococcus multilocularis prolyl endopeptidase 0.0021 0.0005 0.0005
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0011 0.0025
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0006 0.007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0033 0.008
Leishmania major trypanothione reductase 0.0085 0.0051 0.129
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0013 0.0258
Echinococcus granulosus serotonin receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Onchocerca volvulus 0.0095 0.0058 0.1086
Plasmodium vivax SET domain protein, putative 0.0095 0.0058 0.1418
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0027 0.0009 0.0161
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0004 0.0055
Schistosoma mansoni biogenic amine receptor 0.0017 0.0002 0.0002
Echinococcus granulosus Niemann Pick C1 protein 0.0307 0.0212 0.0212
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0066 0.0037 0.0944
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Toxoplasma gondii ribonuclease HI protein 0.0022 0.0006 0.0111
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0005 0.0066
Brugia malayi Intermediate filament tail domain containing protein 0.0126 0.008 0.1011
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Onchocerca volvulus 0.0022 0.0005 0.0078
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0003 0.0006
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0003 0.0003
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0016 0.0001 0.0017
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Schistosoma mansoni ran 0.0047 0.0024 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0005 0.0005
Onchocerca volvulus 0.0123 0.0078 0.1468
Brugia malayi CXXC zinc finger family protein 0.006 0.0033 0.0418
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.0092 0.2339
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0005 0.0057
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0033 0.0033
Trichomonas vaginalis esterase, putative 0.0071 0.0041 0.076
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Brugia malayi topoisomerase 0.0019 0.0003 0.0043
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0012 0.0219
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0022 0.0045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0027 0.0009 0.0161
Echinococcus granulosus importin subunit beta 1 0.0064 0.0036 0.0036
Brugia malayi nuclear receptor RXR 0.0022 0.0005 0.0066
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0033 0.0013 0.0167
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0031 0.0031
Echinococcus multilocularis serotonin receptor 0.0017 0.0002 0.0002
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0027 0.0009 0.0431
Entamoeba histolytica cysteine protease, putative 0.0027 0.0009 0.0431
Brugia malayi cathepsin F-like cysteine proteinase 0.0027 0.0009 0.0119
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0004 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0056 0.105
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0193 0.0129 0.0308
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0556 0.0391 0.0391
Brugia malayi jmjC domain containing protein 0.0019 0.0003 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0037 0.0944
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0066 0.0037 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0023 0.0285
Onchocerca volvulus Cathepsin L homolog 0.0027 0.0009 0.0158
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0044 0.0044
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0002 0.0023
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0027 0.0009 0.0431
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0028 0.001 0.0242
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0092 0.0056 0.0708
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0027 0.0009 0.0161
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0031 0.0031
Schistosoma mansoni cathepsin F (C01 family) 0.0123 0.0078 0.0078
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0002 0.0002
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0231 0.0157 0.0157
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0002 0.0002
Leishmania major ribonuclease H1, putative 0.0022 0.0006 0.0128
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0031 0.0574
Loa Loa (eye worm) steroid hormone receptor 0.0046 0.0023 0.0284
Echinococcus multilocularis cathepsin L cysteine protease 0.0123 0.0078 0.0078
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0088 0.0088
Onchocerca volvulus 0.0017 0.0002 0.0013
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0134 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0064 0.0036 0.0449
Schistosoma mansoni hypothetical protein 0.0477 0.0334 0.0334
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0004 0.0004
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0021 0.0467
Plasmodium vivax vivapain-1 0.0066 0.0037 0.088
Schistosoma mansoni ran 0.0047 0.0024 0.0024
Echinococcus granulosus neuropeptide receptor 0.0017 0.0002 0.0002
Schistosoma mansoni myosin xvIII 0.0017 0.0002 0.0002
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0011 0.0186
Echinococcus granulosus snurportin 1 0.0681 0.0482 0.0482
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0027 0.0009 0.0161
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0061 0.0033 0.0033
Leishmania major DNA polymerase eta, putative 0.0019 0.0003 0.0069
Mycobacterium ulcerans UDP-N-acetylmuramyl tripeptide synthase 0.0556 0.0391 0.0957
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0002 0.0002
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0006 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0009 0.0158
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0002 0.0002
Entamoeba histolytica cysteine proteinase 2 0.0066 0.0037 0.1878
Brugia malayi jmjC domain containing protein 0.0019 0.0003 0.0043
Brugia malayi MAP kinase sur-1 0.0053 0.0028 0.0353
Brugia malayi putative neuropeptide receptor 0.0017 0.0002 0.0023
Schistosoma mansoni cathepsin C 0.0027 0.0009 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0041 0.0092
Echinococcus multilocularis thyroid hormone receptor alpha 0.0046 0.0023 0.0023
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.0058 0.0058
Echinococcus granulosus somatostatin receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.0005 0.0065
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.002 0.0501
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.0005 0.0005
Plasmodium falciparum glutathione reductase 0.0085 0.0051 0.1229
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0003 0.0005
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0027 0.0009 0.0431
Echinococcus granulosus cathepsin l1 0.0084 0.005 0.005
Brugia malayi nuclear hormone receptor 0.0022 0.0005 0.0066
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0033 0.0837
Plasmodium vivax pantothenate kinase, putative 0.0066 0.0038 0.0886
Echinococcus multilocularis musashi 0.0126 0.008 0.008
Plasmodium vivax importin-beta 2, putative 0.0064 0.0036 0.0839
Leishmania major mitochondrial DNA polymerase beta 0.0299 0.0206 0.525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0002 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0194 1
Schistosoma mansoni cathepsin F (C01 family) 0.0123 0.0078 0.0078
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0016 0.0001 0.0001
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0003 0.0043
Brugia malayi nuclear receptor RXR 0.0024 0.0007 0.009
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.141
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0041 0.0099
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0058
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.0088 0.1104
Schistosoma mansoni opsin-like receptor 0.0017 0.0002 0.0002
Brugia malayi ecdysteroid receptor 0.0046 0.0023 0.0285
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0002 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0033 0.0837
Brugia malayi Melatonin receptor type 1A 0.0017 0.0002 0.0023
Echinococcus multilocularis FTZ F1 alpha 0.0046 0.0023 0.0023
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0003 0.0074
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0221
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.018 0.012 0.012
Trypanosoma brucei unspecified product 0.006 0.0033 0.0837
Giardia lamblia Cathepsin L precursor 0.0027 0.0009 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0005 0.0068
Trypanosoma cruzi oligopeptidase b 0.0021 0.0005 0.012
Leishmania major hypothetical protein, conserved 0.003 0.0012 0.0287
Brugia malayi cathepsin L precursor 0.0027 0.0009 0.0119
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0005 0.0005
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0066 0.0038 0.0949
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0011 0.0198
Entamoeba histolytica cysteine protease, putative 0.0027 0.0009 0.0431
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0005 0.0005
Brugia malayi nuclear receptor NHR-67 0.0022 0.0005 0.0066
Giardia lamblia Cathepsin B precursor 0.0085 0.0051 0.2599
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0003 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0069
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Giardia lamblia Ribonuclease H 0.0022 0.0006 0.0225
Brugia malayi cathepsin F-like cysteine proteinase 0.0039 0.0018 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0002 0.0002
Schistosoma mansoni smad1 5 8 and 0.0076 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0221
Schistosoma mansoni cathepsin F (C01 family) 0.0084 0.005 0.005
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0556 0.0391 1
Giardia lamblia Cathepsin B precursor 0.0027 0.0009 0.0431
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.017 0.3216
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Echinococcus granulosus Niemann Pick C1 protein 0.0215 0.0145 0.0145
Brugia malayi hypothetical protein 0.0022 0.0005 0.0066
Schistosoma mansoni phosphoglucomutase 0.0022 0.0006 0.0006
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0002 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0017 0.0002 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0028 0.0511
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0003 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.002 0.0492
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.0004 0.0101
Schistosoma mansoni folylpolyglutamate synthase 0.0556 0.0391 0.0391
Trypanosoma cruzi trypanothione reductase, putative 0.0085 0.0051 0.129
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0041 0.0092
Onchocerca volvulus 0.0017 0.0002 0.0013
Loa Loa (eye worm) nuclear hormone receptor 0.0022 0.0005 0.0065
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0037 0.1878
Mycobacterium ulcerans hypothetical protein 0.0158 0.0104 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Brugia malayi DKFZp564C0469 protein 0.0019 0.0003 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0009 0.0158
Brugia malayi hypothetical protein 0.0022 0.0005 0.0066
Brugia malayi RNase H family protein 0.0022 0.0006 0.0069
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0092 0.2339
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Plasmodium falciparum serine repeat antigen 5 0.0027 0.0009 0.0161
Loa Loa (eye worm) Smad1 0.0076 0.0045 0.056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Brugia malayi jmjC domain containing protein 0.0019 0.0003 0.0043
Giardia lamblia Cathepsin L precursor 0.0027 0.0009 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.004
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0095 0.0058 0.0731
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0214 0.0145 0.3688
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0092 0.2339
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0046 0.0023 0.0023
Loa Loa (eye worm) DR-78 0.0022 0.0005 0.0065
Echinococcus multilocularis nibrin 0.0019 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0067 0.0038 0.1923
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0015 0.0015
Echinococcus granulosus ribonuclease H1 0.0022 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0046 0.0023 0.0285
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0001 0.0005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.0005 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0033 0.061
Treponema pallidum NADH oxidase 0.0029 0.0011 0.0018
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.009 0.0218
Loa Loa (eye worm) hypothetical protein 0.0094 0.0058 0.0727
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0047 0.0024 0.0526
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.017 0.3216
Giardia lamblia Cathepsin B precursor 0.0027 0.0009 0.0431
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0089
Mycobacterium tuberculosis Conserved protein 0.0071 0.0041 0.0092
Loa Loa (eye worm) hypothetical protein 0.0477 0.0334 0.4202
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0002 0.0002
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0123 0.0078 0.0984
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Loa Loa (eye worm) hypothetical protein 0.0061 0.0033 0.042
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0005 0.0057
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0041 0.0092
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0011 0.0267
Brugia malayi photoreceptor-specific nuclear receptor 0.0046 0.0023 0.0285
Leishmania major cathepsin L-like protease 0.0123 0.0078 0.1991
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0037 0.1878
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0004 0.0004
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0058 0.0058
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0215 0.0145 0.1822
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0085 0.0085
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0556 0.0391 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0014 0.0178
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0011 0.0267
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0016 0.0001 0.0001
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0134 0.0087 0.2205
Brugia malayi nuclear receptor NHR-88 0.0022 0.0005 0.0066
Echinococcus granulosus neuropeptide receptor A26 0.0017 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0002 0.0002
Brugia malayi ORL1-like opioid receptor 0.0017 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni opsin-like receptor 0.0017 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0046 0.0023 0.0285
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0133
Leishmania major DNA damage repair protein, putative 0.0019 0.0003 0.0069
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0046 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.1116 0.0796 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0027 0.0009 0.0431
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0046 0.0023 0.0285
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0000087314 0.0000087314
Schistosoma mansoni biogenic amine receptor 0.0017 0.0002 0.0002
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0004 0.0101
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0023 0.0285
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0097 0.0097
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0024 0.0007 0.0007
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0047 0.0024 0.0576
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Leishmania major folylpolyglutamate synthetase 0.0556 0.0391 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0003 0.0042
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0003 0.0069
Onchocerca volvulus Prolyl endopeptidase homolog 0.0021 0.0005 0.0077
Leishmania major oligopeptidase b 0.0021 0.0005 0.012
Schistosoma mansoni ap endonuclease 0.0022 0.0005 0.0005
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0014 0.0178
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0003 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0046 0.0023 0.0023
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0002 0.0022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0004 0.0056
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0009 0.0119
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0516
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0088
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0033 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0005 0.012
Mycobacterium tuberculosis Conserved protein 0.0071 0.0041 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.017 0.3216
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trichomonas vaginalis importin beta-1, putative 0.0052 0.0027 0.0493
Brugia malayi prolyl oligopeptidase family protein 0.0021 0.0005 0.0065
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0058 0.1463
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0076 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Trypanosoma cruzi cysteine peptidase, putative 0.0179 0.0119 0.3041
Schistosoma mansoni coup transcription factor 0.0046 0.0023 0.0023
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0003 0.0003
Toxoplasma gondii HEAT repeat-containing protein 0.0064 0.0036 0.0888
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0003 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0193 0.0129 0.0308
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0024 0.0007 0.0162
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0005 0.0222
Plasmodium falciparum serine repeat antigen 1 0.0027 0.0009 0.0161
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0002 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0477 0.0334 0.4203
Echinococcus granulosus cathepsin L 0.0066 0.0037 0.0037
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0002 0.0002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0046 0.0023 0.0409
Schistosoma mansoni patched 1 0.0092 0.0056 0.0056
Schistosoma mansoni cpg binding protein 0.0064 0.0036 0.0036
Entamoeba histolytica cysteine protease, putative 0.0027 0.0009 0.0431
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0027 0.0009 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Echinococcus granulosus serine protein kinase ATM 0.0028 0.001 0.001
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0031 0.0031
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0556 0.0391 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0133
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0004 0.0101
Mycobacterium tuberculosis Probable oxidoreductase 0.0215 0.0145 0.0346
Brugia malayi Papain family cysteine protease containing protein 0.0066 0.0037 0.047
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0088
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0295 0.0203 0.0203
Giardia lamblia Cathepsin B precursor 0.0085 0.0051 0.2599
Toxoplasma gondii thioredoxin reductase 0.0085 0.0051 0.1275
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0193 0.0129 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0041 0.076
Echinococcus multilocularis ecdysone induced protein 78C 0.0046 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0021 0.0005 0.0004
Schistosoma mansoni smad 0.0076 0.0045 0.0045
Leishmania major cathepsin L-like protease 0.0123 0.0078 0.1991
Schistosoma mansoni hypothetical protein 0.0221 0.0149 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0046 0.0023 0.0284
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0133
Echinococcus granulosus mothers against decapentaplegic 5 0.0076 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0516
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0115 0.2157
Loa Loa (eye worm) beta-lactamase 0.0071 0.0041 0.0516
Echinococcus multilocularis smad 0.0076 0.0045 0.0045
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0003 0.0053
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0221 0.0149 0.1876
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0027 0.0009 0.0431
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus granulosus cysteine protease 0.0066 0.0037 0.0037
Echinococcus granulosus tar DNA binding protein 0.0957 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Plasmodium falciparum glutathione reductase 0.0029 0.0011 0.0198
Schistosoma mansoni hypothetical protein 0.0067 0.0038 0.0038
Trypanosoma cruzi cysteine protease, putative 0.0066 0.0037 0.0944
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0014 0.0178
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Loa Loa (eye worm) inositol-1 0.0045 0.0022 0.0275
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0067 0.0038 0.1923
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0002 0.0002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0011 0.0025
Brugia malayi MH2 domain containing protein 0.0034 0.0014 0.0179
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0011 0.025
Brugia malayi Cytochrome P450 family protein 0.0028 0.001 0.0127
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis protein patched 0.0092 0.0056 0.0056
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0021 0.0005 0.0005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0698 0.0494 0.6208
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0004 0.0056
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.002 0.0492
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0012 0.0207
Echinococcus granulosus acylamino acid releasing enzyme 0.0021 0.0005 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0004 0.0055
Brugia malayi nuclear receptor NHR-88 0.0046 0.0023 0.0285
Onchocerca volvulus Cathepsin L homolog 0.0123 0.0078 0.1468
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0033 0.0418
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0088
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0027 0.0009 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0046 0.0023 0.0284
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0042
Plasmodium falciparum importin beta, putative 0.0064 0.0036 0.0839
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0011 0.0198
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0005 0.0126
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0023 0.0285
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0042 0.0042
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramate-alanine ligase 0.3285 0.2363 0.5777
Mycobacterium tuberculosis Probable dehydrogenase 0.0193 0.0129 0.0308
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0221
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0123 0.0078 0.0078
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0091 0.0055 0.1388
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus multilocularis lamin dm0 0.0126 0.008 0.008
Schistosoma mansoni smad1 5 8 and 0.0076 0.0045 0.0045
Toxoplasma gondii cathepsin CPL 0.0123 0.0078 0.1978
Schistosoma mansoni ap endonuclease 0.0022 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0023 0.0285
Echinococcus granulosus mothers against decapentaplegic 6 0.0034 0.0014 0.0014
Brugia malayi sulfakinin receptor protein 0.0017 0.0002 0.0023
Onchocerca volvulus Cathepsin F homolog 0.0123 0.0078 0.1468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0123 0.0078 0.0984
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0067 0.0038 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0004 0.0004
Echinococcus multilocularis nmda type glutamate receptor 0.0027 0.0009 0.0009
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0002 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0003 0.0069
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.1676 0.1201 0.2936
Trypanosoma brucei unspecified product 0.0024 0.0007 0.0162
Onchocerca volvulus 0.0744 0.0527 1
Plasmodium vivax glutathione reductase, putative 0.0085 0.0051 0.1229
Mycobacterium ulcerans lipase LipD 0.0071 0.0041 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) hypothetical protein 0.0058 0.0032 0.0399
Onchocerca volvulus 0.0017 0.0002 0.0013
Brugia malayi RNA recognition motif domain containing protein 0.0957 0.0681 0.856
Giardia lamblia DNA damage repair protein 0.0019 0.0003 0.0107
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0033 0.008
Schistosoma mansoni DNA polymerase eta 0.006 0.0033 0.0033
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0046 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0043
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0042 0.0042
Plasmodium vivax JmjC domain containing protein 0.0019 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0343 0.0238 0.2986
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Brugia malayi FolC bifunctional protein 0.0556 0.0391 0.492
Trypanosoma brucei unspecified product 0.0042 0.002 0.0492
Giardia lamblia Hypothetical protein 0.0027 0.0009 0.0431
Brugia malayi neuropeptide F receptor 0.0017 0.0002 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0005 0.0005
Mycobacterium ulcerans UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 0.1676 0.1201 0.2936
Treponema pallidum folylpolyglutamate synthetase (folC) 0.1676 0.1201 0.2931
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0013 0.0258
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0011 0.0018
Trypanosoma cruzi folylpolyglutamate synthetase 0.0556 0.0391 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0022 0.0395
Giardia lamblia Cathepsin B precursor 0.0027 0.0009 0.0431
Brugia malayi Importin beta-1 subunit 0.0064 0.0036 0.045
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0021 0.0005 0.0011
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0295 0.0203 0.0203
Leishmania major cathepsin L-like protease 0.0123 0.0078 0.1991
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0002 0.0002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0286 0.0196 0.2463
Brugia malayi follicle stimulating hormone receptor 0.0244 0.0166 0.2089
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0011 0.0267
Onchocerca volvulus 0.0123 0.0078 0.1468
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0041 0.0041
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0066 0.0037 0.0037
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0028 0.0352
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0516
Brugia malayi Serine protease Z688.6 precursor 0.0016 0.0001 0.0015
Brugia malayi mbt repeat family protein 0.0058 0.0031 0.0394
Onchocerca volvulus 0.0071 0.0041 0.076
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0016 0.0001 0.0001
Echinococcus multilocularis expressed conserved protein 0.0202 0.0136 0.0136
Echinococcus granulosus hypothetical protein 0.0017 0.0002 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0046 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0118
Trichomonas vaginalis pantothenate kinase, putative 0.0066 0.0038 0.0693
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0028 0.0704
Schistosoma mansoni hypothetical protein 0.0681 0.0482 0.0482
Schistosoma mansoni hypothetical protein 0.0682 0.0483 0.0483
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor 0.0017 0.0002 0.0002
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0011 0.0198
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0034 0.0014 0.0249
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0003 0.0074
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0021 0.0005 0.012
Plasmodium falciparum serine repeat antigen 2 0.0027 0.0009 0.0161
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0002 0.0002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0005 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.0066 0.0037 0.047
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0044 0.0546
Schistosoma mansoni amine GPCR 0.0017 0.0002 0.0002
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0041 0.0041
Brugia malayi cathepsin Z-like cysteine proteinase 0.0027 0.0009 0.0119
Echinococcus granulosus dnaJ subfamily B 0.0397 0.0277 0.0277
Echinococcus multilocularis mothers against decapentaplegic 6 0.0034 0.0014 0.0014
Plasmodium falciparum serine repeat antigen 7 0.0027 0.0009 0.0161
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0022 0.0548
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0034 0.0034
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0046 0.0023 0.0023
Echinococcus granulosus expressed conserved protein 0.0202 0.0136 0.0136
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0003 0.0003
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0004 0.0004
Toxoplasma gondii cathepsin CPC2 0.0027 0.0009 0.0213
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) FolC protein 0.0556 0.0391 0.4919
Plasmodium falciparum serine repeat antigen 9 0.0027 0.0009 0.0161
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0077 0.1951
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0033 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0041 0.1039
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0074
Brugia malayi RNA, U transporter 1 0.0181 0.0121 0.1518
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0071 0.0041 0.1031
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.001 0.0125
Brugia malayi Cathepsin L-like precursor 0.0123 0.0078 0.0985
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0027 0.0009 0.0119
Onchocerca volvulus 0.0017 0.0002 0.0013
Onchocerca volvulus 0.0017 0.0002 0.0013
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0022 0.0395
Brugia malayi N-terminal motif family protein 0.0222 0.015 0.1884
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0033 0.0837
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0027 0.0009 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0011 0.0267
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0058 0.0058
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0017 0.0002 0.0013
Plasmodium vivax thioredoxin reductase, putative 0.0085 0.0051 0.1229
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0021 0.0384
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0058 0.0058
Onchocerca volvulus 0.0123 0.0078 0.1468
Echinococcus granulosus geminin 0.0682 0.0483 0.0483
Brugia malayi jmjC domain containing protein 0.0071 0.0041 0.0516
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0193 0.0129 0.0308
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0023 0.0285
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0299 0.0206 0.525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0194 0.3669
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0064
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Toxoplasma gondii ABC1 family protein 0.0071 0.0041 0.1024
Plasmodium falciparum thioredoxin reductase 0.0085 0.0051 0.1229
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0021 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0033 0.0837
Onchocerca volvulus 0.0046 0.0023 0.0409
Loa Loa (eye worm) hypothetical protein 0.0214 0.0145 0.1818
Schistosoma mansoni transcription factor LCR-F1 0.0067 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0069 0.004 0.05
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.0005 0.0066
Echinococcus granulosus neuropeptide s receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0009 0.0118
Brugia malayi Dopamine receptor protein 1 0.0017 0.0002 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0075
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0005 0.0005
Giardia lamblia Alanyl dipeptidyl peptidase 0.0021 0.0005 0.0209
Chlamydia trachomatis bifunctional UDP-N-acetylmuramate-alanine ligase/D-alanine-D-alanine ligase 0.3285 0.2363 0.5777
Giardia lamblia Cathepsin L precursor 0.0027 0.0009 0.0431
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0046 0.0023 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0118
Schistosoma mansoni opsin-like receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) cysteine protease 0.0123 0.0078 0.0984
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0028 0.0704
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0022 0.0005 0.0078
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0007 0.0007
Onchocerca volvulus 0.0126 0.008 0.1507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0009 0.0158
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0085 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.0633
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0005 0.0004
Brugia malayi Cathepsin L-like precursor 0.0084 0.005 0.0634
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0027 0.0009 0.0161
Echinococcus multilocularis cathepsin L 0.0066 0.0037 0.0037
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0031 0.0031
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0123 0.0078 0.1935
Onchocerca volvulus 0.0343 0.0238 0.4496
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.0044 0.0044
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0134 0.0087 0.2205
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0023 0.0285
Echinococcus granulosus orexin receptor type 2 0.0017 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0005 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0123 0.0078 0.0985
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0002 0.0002
Schistosoma mansoni histamine h1 receptor 0.0017 0.0002 0.0002
Toxoplasma gondii prolyl endopeptidase 0.0021 0.0005 0.0103
Echinococcus granulosus pantothenate kinase 4 0.0066 0.0038 0.0038
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0021 0.0005 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0179 0.0119 0.3041
Brugia malayi Serine protease Z688.6 precursor 0.0016 0.0001 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.017 0.3216
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0046 0.0023 0.0023
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0005 0.0067
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0033 0.0033
Onchocerca volvulus Fumble homolog 0.0066 0.0038 0.0693
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0046 0.0023 0.0285
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0046 0.0023 0.0023
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.0058 0.141
Schistosoma mansoni lamin 0.0126 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Loa Loa (eye worm) prolyl oligopeptidase 0.018 0.012 0.1509
Entamoeba histolytica hypothetical protein 0.0028 0.001 0.0456
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Onchocerca volvulus 0.0123 0.0078 0.1468
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.002 0.0501
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0004 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0123 0.0078 0.1468
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0019 0.0004 0.0008
Brugia malayi tailless protein 0.0022 0.0005 0.0066
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trypanosoma brucei ingi protein (ORF1) 0.0024 0.0007 0.0162
Schistosoma mansoni retinoic acid receptor RXR 0.0046 0.0023 0.0023
Onchocerca volvulus 0.006 0.0033 0.061
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0193 0.0129 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0084 0.005 0.0937
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0005 0.0126
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0028 0.001 0.0173
Brugia malayi Latrophilin receptor protein 2 0.0221 0.0149 0.1876
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0218 0.0147 0.0147
Treponema pallidum UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD) 0.1676 0.1201 0.2931
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.0277 0.0277
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0022 0.0533
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0085 0.0051 0.1299
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0284
Trypanosoma brucei oligopeptidase b 0.0021 0.0005 0.012
Brugia malayi TAR-binding protein 0.0957 0.0681 0.856
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0033 0.0073
Echinococcus multilocularis cathepsin L cysteine protease 0.0123 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.0005 0.0066
Echinococcus multilocularis mothers against decapentaplegic 2 0.0034 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.0005 0.0065
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Echinococcus granulosus cpg binding protein 0.0064 0.0036 0.0036
Schistosoma mansoni nuclear receptor 0.0022 0.0005 0.0005
Echinococcus granulosus cathepsin l cysteine peptidase 0.0123 0.0078 0.0078
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0003 0.0003
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0141
Schistosoma mansoni neuropeptide receptor 0.0017 0.0002 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0005 0.0078
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0021 0.0384
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0126 0.008 0.101
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Loa Loa (eye worm) hypothetical protein 0.0113 0.0071 0.0896
Echinococcus granulosus lamin 0.0126 0.008 0.008
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0016 0.0001 0.0017
Mycobacterium ulcerans UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase 0.3285 0.2363 0.578
Plasmodium falciparum thioredoxin reductase 0.0029 0.0011 0.0198
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0023 0.0023
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0027 0.0009 0.0161
Schistosoma mansoni inositol monophosphatase 0.0045 0.0022 0.0022
Schistosoma mansoni importin beta-1 0.0064 0.0036 0.0036
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0005 0.0126
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0046 0.0023 0.0023
Mycobacterium ulcerans hypothetical protein 0.0019 0.0003 0.0007
Loa Loa (eye worm) TAR-binding protein 0.0957 0.0681 0.856
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0003 0.0069
Schistosoma mansoni inositol monophosphatase 0.0045 0.0022 0.0022
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0017 0.0002 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0004 0.0063
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0011 0.0267
Brugia malayi pantothenate kinase family protein 0.0066 0.0038 0.0473
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0065
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0003 0.0043
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0067 0.0038 0.048
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0214 0.0145 0.0145
Toxoplasma gondii hypothetical protein 0.0021 0.0005 0.0103
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0097 0.1222
Treponema pallidum UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (murE) 0.3285 0.2363 0.5777
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0047 0.0024 0.0592
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0295 0.0203 0.0203
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0019 0.0909
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0028 0.0511
Brugia malayi cathepsin B-like cysteine proteinase 0.0214 0.0145 0.1819
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0043
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.001 0.0242
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0123 0.0078 0.1468
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.017 0.3216
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0021 0.0005 0.0077
Echinococcus multilocularis somatostatin receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0088
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0516
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0556 0.0391 0.7421
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0002 0.0002
Echinococcus multilocularis dna polymerase kappa 0.006 0.0033 0.0033
Trichomonas vaginalis pantothenate kinase, putative 0.0066 0.0038 0.0693
Loa Loa (eye worm) ctsf protein 0.0123 0.0078 0.0984
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Brugia malayi cathepsin Z-like cysteine proteinase 0.0027 0.0009 0.0119
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0003 0.0069
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0957 0.0681 0.0681
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0017 0.0002 0.0023
Trichomonas vaginalis pantothenate kinase, putative 0.0066 0.0038 0.0693
Schistosoma mansoni hypothetical protein 0.0089 0.0054 0.0054
Brugia malayi hypothetical protein 0.0024 0.0007 0.009
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0011 0.0267
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0047 0.0024 0.0024
Echinococcus granulosus smad 0.0076 0.0045 0.0045
Onchocerca volvulus 0.0017 0.0002 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.001 0.0167
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.0005 0.0005
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0003 0.0003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0002 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0003 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0046 0.0023 0.0285
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0214 0.0145 0.0145
Schistosoma mansoni thyroid hormone receptor 0.0046 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.0179 0.0119 0.3041
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.0251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0009 0.0158
Brugia malayi beta-lactamase family protein 0.0071 0.0041 0.0517
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0698 0.0494 0.6208
Loa Loa (eye worm) glutathione reductase 0.0085 0.0051 0.0639
Entamoeba histolytica cysteine protease, putative 0.0066 0.0037 0.1878
Schistosoma mansoni smad 0.0034 0.0014 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0108 0.2036
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0003 0.0003
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0058 0.0141
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0027 0.0009 0.0161
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0002 0.0002
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0031 0.0031
Chlamydia trachomatis UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminoligase 0.5672 0.4088 1
Onchocerca volvulus 0.0017 0.0002 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0033 0.0418
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0015 0.0015
Onchocerca volvulus Bile acid receptor homolog 0.0046 0.0023 0.0409
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0005 0.0081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0084 0.005 0.0937

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) > 112.219 um PUBCHEM_BIOASSAY: Luminescence Biochemical Dose Response HTS to Identify Inhibitors of Luciferase. (Class of assay: confirmatory) [Related pubchem assays: 1663 (Primary HTS), 1678 (Summary of Project)] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) 8.1995 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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