Detailed information for compound 1373657

Basic information

Technical information
  • TDR Targets ID: 1373657
  • Name: [2-[di(phenyl)methyl-methylamino]-2-oxoethyl] 3-(1H-indol-3-yl)propanoate
  • MW: 426.507 | Formula: C27H26N2O3
  • H donors: 1 H acceptors: 2 LogP: 4.85 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CCc1c[nH]c2c1cccc2)OCC(=O)N(C(c1ccccc1)c1ccccc1)C
  • InChi: 1S/C27H26N2O3/c1-29(27(20-10-4-2-5-11-20)21-12-6-3-7-13-21)25(30)19-32-26(31)17-16-22-18-28-24-15-9-8-14-23(22)24/h2-15,18,27-28H,16-17,19H2,1H3
  • InChiKey: SUKWRYQWHSYEFF-UHFFFAOYSA-N  

Network

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Synonyms

  • [2-[di(phenyl)methyl-methyl-amino]-2-oxo-ethyl] 3-(1H-indol-3-yl)propanoate
  • 3-(1H-indol-3-yl)propanoic acid [2-[di(phenyl)methyl-methylamino]-2-oxoethyl] ester
  • 3-(1H-indol-3-yl)propionic acid [2-[di(phenyl)methyl-methyl-amino]-2-keto-ethyl] ester
  • T5217346
  • MLS000389654
  • SMR000255928

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens glucosidase, alpha Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) glycosyl hydrolase family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum ko:K01187 alpha-glucosidase [EC3.2.1.20], putative Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum Lysosomal alpha-glucosidase precursor, putative Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Brugia malayi Glycosyl hydrolases family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Onchocerca volvulus Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium vivax hypothetical protein, conserved 0.0035 0.005 0.0955
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.049 0.3986 0.5581
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0436 0.0388
Loa Loa (eye worm) hypothetical protein 0.049 0.3986 0.5569
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0124 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0279 0.023
Treponema pallidum fructose-bisphosphate aldolase 0.1185 1 0.5
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0161 0.0207
Trichomonas vaginalis chromobox protein, putative 0.0129 0.0865 0.082
Brugia malayi M-phase phosphoprotein, mpp8 0.0035 0.005 0.007
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0218 0.029
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0122 0.0151
Echinococcus granulosus histone lysine methyltransferase setb 0.0079 0.0429 0.0593
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0124 0.0075
Onchocerca volvulus 0.0094 0.0562 0.0722
Schistosoma mansoni alpha-glucosidase 0.0169 0.1212 0.1742
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0019 0.0027
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1185 1 1
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.6959 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.005 0.0955
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0124 0.0174
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0041 0.0102 0.0116
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0161 0.0207
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0122 0.0151
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0161 0.0231
Brugia malayi Importin beta-1 subunit 0.0032 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0365 0.2902 0.4047
Echinococcus multilocularis chromobox protein 2 0.0035 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Echinococcus multilocularis Chromo domain 0.0035 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Loa Loa (eye worm) PHD-finger family protein 0.009 0.0523 0.0706
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.005 0.007
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0279 0.4957
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0279 0.0377
Loa Loa (eye worm) hypothetical protein 0.049 0.3986 0.5569
Loa Loa (eye worm) hypothetical protein 0.0052 0.0192 0.0241
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.037 0.0509
Toxoplasma gondii PHD-finger domain-containing protein 0.009 0.0523 1
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0279 0.0401
Brugia malayi hypothetical protein 0.049 0.3986 0.5581
Loa Loa (eye worm) hypothetical protein 0.0048 0.0161 0.0197
Loa Loa (eye worm) hypothetical protein 0.012 0.0781 0.1069
Schistosoma mansoni chromobox protein 0.0214 0.1602 0.2302
Loa Loa (eye worm) hypothetical protein 0.0046 0.0147 0.0179
Schistosoma mansoni hypothetical protein 0.009 0.0523 0.0751
Trichomonas vaginalis set domain proteins, putative 0.0462 0.3748 0.3717
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.005 0.007
Loa Loa (eye worm) heterochromatin protein 1 0.0214 0.1602 0.2221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0161 0.0231
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0161 0.0207
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0079 0.0429 0.0593
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0279 0.4957
Brugia malayi RNA, U transporter 1 0.009 0.0525 0.0736
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.002 0.0463
Trichomonas vaginalis chromobox protein, putative 0.0214 0.1602 0.156
Echinococcus multilocularis lysine specific demethylase 5A 0.0109 0.0686 0.0964
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.007 0.0076
Echinococcus granulosus chromobox protein 2 0.0035 0.005 0.0048
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0129 0.0865 0.115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0429 0.0616
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0218 0.029
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.458 0.6573
Loa Loa (eye worm) hypothetical protein 0.0049 0.0172 0.0213
Onchocerca volvulus Huntingtin homolog 0.012 0.0781 0.1031
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0102 0.0143
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0218 0.029
Echinococcus multilocularis snurportin 1 0.0338 0.2671 0.3823
Schistosoma mansoni hypothetical protein 0.0035 0.005 0.0072
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0436 0.0584
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.037 0.0509
Brugia malayi jmjC domain containing protein 0.0294 0.2289 0.3206
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0124 0.0075
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0436 0.0604
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0058 0.0251 0.4793
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0436 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.007 0.0076
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.009 0.0523 0.0751
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.002 0.0386
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0579 0.4755 0.5
Onchocerca volvulus 0.0854 0.7142 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0338 0.2671 0.3723
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.005 0.0955
Brugia malayi mbt repeat family protein 0.0048 0.0161 0.0225
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.1449 0.2063
Schistosoma mansoni hypothetical protein 0.0205 0.1517 0.218
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0124 0.0075
Loa Loa (eye worm) hypothetical protein 0.049 0.3986 0.5569
Brugia malayi Bromodomain containing protein 0.0046 0.0147 0.0205
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0279 0.4957
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0429 0.0616
Onchocerca volvulus 0.0854 0.7142 1
Trypanosoma brucei protein kinase, putative 0.0062 0.0279 0.6392
Loa Loa (eye worm) MBCTL1 0.0054 0.0218 0.0278
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.0706 0.1015
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0189 0.1379 0.1962
Brugia malayi hypothetical protein 0.0365 0.2902 0.4064
Loa Loa (eye worm) jmjC domain-containing protein 0.0111 0.0706 0.0963
Schistosoma mansoni jumonji domain containing protein 0.0233 0.1767 0.2539
Brugia malayi hypothetical protein 0.049 0.3986 0.5581
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Onchocerca volvulus Alhambra homolog 0.009 0.0523 0.0667
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0854 0.7142 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0562 0.0761
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0786 0.074
Echinococcus granulosus Chromo domain 0.0035 0.005 0.0048
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.005 0.0072
Schistosoma mansoni hypothetical protein 0.0338 0.2671 0.3838
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.0706 0.1015
Plasmodium vivax hypothetical protein, conserved 0.009 0.0523 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0279 0.0377
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.458 0.6573
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.049 0.3986 0.5581
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.005 0.0955
Giardia lamblia PHD finger protein 15 0.009 0.0523 0.0251
Onchocerca volvulus 0.0854 0.7142 1
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.005 0.0072
Echinococcus granulosus chromobox protein 1 0.0214 0.1602 0.2283
Brugia malayi hypothetical protein 0.0035 0.005 0.007
Schistosoma mansoni chromobox protein 0.0214 0.1602 0.2302
Echinococcus granulosus geminin 0.0205 0.1517 0.2161
Onchocerca volvulus 0.0048 0.0161 0.0156
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0436 0.0611
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0124 0.0075
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0294 0.2289 0.3274
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.005 0.0955
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0579 0.4755 0.5
Onchocerca volvulus 0.0854 0.7142 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0436 1
Brugia malayi Protein cec-1. 0.0035 0.005 0.007
Onchocerca volvulus Huntingtin homolog 0.012 0.0781 0.1031
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0279 0.0377
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0058 0.0251 0.0337
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0854 0.7142 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0124 0.0075
Brugia malayi jmjC domain containing protein 0.0111 0.0706 0.0989
Plasmodium falciparum heterochromatin protein 1 0.0035 0.005 0.0955
Loa Loa (eye worm) hypothetical protein 0.0079 0.0429 0.0574
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0146 0.0185
Schistosoma mansoni alpha-glucosidase 0.0169 0.1212 0.1742
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0124 0.0075
Echinococcus granulosus PHD finger protein rhinoceros 0.009 0.0523 0.0729
Onchocerca volvulus 0.0854 0.7142 1
Brugia malayi MAP kinase sur-1 0.0062 0.0279 0.039
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0124 0.0146
Onchocerca volvulus 0.0854 0.7142 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.005 0.0048
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0279 0.4957
Onchocerca volvulus 0.0093 0.0554 0.0711
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0133 0.0167
Schistosoma mansoni chromobox protein 0.0035 0.005 0.0072
Brugia malayi hypothetical protein 0.012 0.0781 0.1094
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0436 0.0604
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0133 0.0191
Echinococcus multilocularis PHD finger protein rhinoceros 0.009 0.0523 0.0729
Brugia malayi Heterochromatin protein 1 0.0214 0.1602 0.2243
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.005 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0483 0.0435
Echinococcus granulosus microtubule associated protein 2 0.0833 0.6959 1
Schistosoma mansoni chromobox protein 0.0035 0.005 0.0072
Brugia malayi F/Y-rich N-terminus family protein 0.0034 0.0039 0.0054
Echinococcus multilocularis peregrin 0.0093 0.0547 0.0764
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0279 0.4957
Onchocerca volvulus 0.0114 0.0731 0.0961
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0279 0.6392
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0267 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0786 0.074
Trypanosoma brucei glucosidase, putative 0.0044 0.0124 0.2845
Echinococcus multilocularis importin subunit beta 1 0.0032 0.002 0.0005
Echinococcus multilocularis chromobox protein 1 0.0214 0.1602 0.2283
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0189 0.1379 0.1962
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0161 0.0156
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0133 0.0167
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.049 0.3986 0.5569
Brugia malayi Pre-SET motif family protein 0.0406 0.3262 0.4568
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0133 0.0186
Onchocerca volvulus Heterochromatin protein 1 homolog 0.012 0.0786 0.1039
Plasmodium vivax importin-beta 2, putative 0.0032 0.002 0.0386
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0218 0.029
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0554 0.0796
Loa Loa (eye worm) hypothetical protein 0.0854 0.7142 1
Onchocerca volvulus 0.0854 0.7142 1
Brugia malayi PHD-finger family protein 0.009 0.0523 0.0732
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0146 0.0185
Loa Loa (eye worm) hypothetical protein 0.0365 0.2902 0.4047
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.049 0.3986 0.5581
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0267 0.0374
Echinococcus granulosus jumonji domain containing protein 0.0125 0.0827 0.1167
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0436 0.0627
Schistosoma mansoni hypothetical protein 0.0291 0.2265 0.3254
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0279 0.5333
Brugia malayi Bromodomain containing protein 0.0093 0.0547 0.0767
Plasmodium falciparum phd finger protein, putative 0.009 0.0523 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0124 0.0075
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0436 1
Trichomonas vaginalis chromobox protein, putative 0.0129 0.0865 0.082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0133 0.0191
Loa Loa (eye worm) hypothetical protein 0.0154 0.1077 0.1485
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.005 0.0072
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0124 0.0075
Brugia malayi PHD-finger family protein 0.003 0.0007 0.0009
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0279 0.0363
Loa Loa (eye worm) hypothetical protein 0.012 0.0781 0.1069
Loa Loa (eye worm) hypothetical protein 0.012 0.0786 0.1076
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0218 0.0313
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.005 0.0955
Plasmodium vivax hypothetical protein, conserved 0.0035 0.005 0.0955
Giardia lamblia Fructose-bisphosphate aldolase 0.1185 1 1
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Loa Loa (eye worm) jmjC domain-containing protein 0.0185 0.135 0.1867
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.1449 0.2007
Onchocerca volvulus 0.0462 0.3748 0.5215
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0279 0.0377
Schistosoma mansoni alpha glucosidase 0.0044 0.0124 0.0178
Loa Loa (eye worm) hypothetical protein 0.009 0.0523 0.0706
Trichomonas vaginalis chromobox protein, putative 0.0214 0.1602 0.156
Loa Loa (eye worm) hypothetical protein 0.0054 0.0218 0.0278
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.007 0.01
Schistosoma mansoni hypothetical protein 0.0205 0.1517 0.218
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0124 0.0155
Echinococcus granulosus lysine specific demethylase 5A 0.0111 0.0706 0.0993
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0406 0.3262 0.4553
Echinococcus granulosus chromobox protein 1 0.0214 0.1602 0.2283
Loa Loa (eye worm) hypothetical protein 0.0365 0.2902 0.4047
Echinococcus multilocularis chromobox protein 1 0.0214 0.1602 0.2283
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0124 0.2374
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0279 0.023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0267 0.0347
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0436 1
Loa Loa (eye worm) hypothetical protein 0.0365 0.2902 0.4047
Onchocerca volvulus 0.0035 0.005 0.000000029788
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0124 0.0075
Brugia malayi chromobox protein homolog 3 0.012 0.0786 0.1101
Echinococcus multilocularis jumonji domain containing protein 0.0125 0.0827 0.1167
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0279 0.4957
Loa Loa (eye worm) hypothetical protein 0.049 0.3986 0.5569
Loa Loa (eye worm) hypothetical protein 0.0085 0.0485 0.0654
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0161 0.0207
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0232 0.031
Schistosoma mansoni importin beta-1 0.0032 0.002 0.0029
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0218 0.0305
Loa Loa (eye worm) hypothetical protein 0.006 0.0267 0.0347
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0161 0.0197
Brugia malayi LBP/BPI 0.0365 0.2902 0.4064
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.458 0.6573
Echinococcus granulosus peregrin 0.0093 0.0547 0.0764
Onchocerca volvulus 0.049 0.3986 0.555
Loa Loa (eye worm) helicase 0.0035 0.005 0.0042
Brugia malayi Valyl-tRNA synthetase 0.0035 0.005 0.007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0133 0.0191
Brugia malayi SET domain containing protein 0.0037 0.0068 0.0096
Onchocerca volvulus 0.049 0.3986 0.555
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0133 0.0158
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0294 0.2289 0.3274
Schistosoma mansoni hypothetical protein 0.0041 0.0102 0.0147
Echinococcus granulosus neuropeptide s receptor 0.0558 0.458 0.6573
Trichomonas vaginalis conserved hypothetical protein 0.0365 0.2902 0.2867
Brugia malayi Pre-SET motif family protein 0.0058 0.0251 0.0351
Schistosoma mansoni bromodomain containing protein 0.0076 0.0408 0.0586
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0161 0.0231
Plasmodium falciparum importin beta, putative 0.0032 0.002 0.0386
Echinococcus granulosus Chromobox protein 3 0.0035 0.005 0.0048
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.6959 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0133 0.0167
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.002 0.0463
Echinococcus multilocularis geminin 0.0205 0.1517 0.2161
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0133 0.0167
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0579 0.4755 0.5
Brugia malayi mbt repeat family protein 0.0048 0.0161 0.0225
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0124 0.0075
Brugia malayi Bromodomain containing protein 0.0091 0.053 0.0742
Echinococcus granulosus snurportin 1 0.0338 0.2671 0.3823
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0279 0.023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0251 0.036
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0279 0.023
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.1449 0.2063
Onchocerca volvulus 0.0365 0.2902 0.4022
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.1449 0.2029
Plasmodium vivax SET domain protein, putative 0.0058 0.0251 0.4793
Loa Loa (eye worm) hypothetical protein 0.049 0.3986 0.5569
Toxoplasma gondii PHD-finger domain-containing protein 0.009 0.0523 1
Brugia malayi PHD-finger family protein 0.0032 0.002 0.0028
Echinococcus granulosus importin subunit beta 1 0.0032 0.002 0.0005
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0124 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Brugia malayi CHD4 protein 0.0037 0.007 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0483 0.0435
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.0042
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.005 0.0955
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0854 0.7142 1
Onchocerca volvulus 0.0854 0.7142 1
Echinococcus multilocularis Chromobox protein 3 0.0035 0.005 0.0048
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.049 0.3986 0.5569
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.1449 0.2063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0854 0.7142 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1185 1 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.5805 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 70.7946 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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