Detailed information for compound 1394485
Basic information
Technical information
- TDR Targets ID: 1394485
- Name: N-(2,2-dimethyloxan-4-yl)-4-morpholin-4-ylsul fonylbenzenesulfonamide
- MW: 418.528 | Formula: C17H26N2O6S2
-
H donors: 1
H acceptors: 4
LogP: 0.69
Rotable bonds: 5
Rule of 5 violations (Lipinski): 1 - SMILES: CC1(C)OCCC(C1)NS(=O)(=O)c1ccc(cc1)S(=O)(=O)N1CCOCC1
- InChi: 1S/C17H26N2O6S2/c1-17(2)13-14(7-10-25-17)18-26(20,21)15-3-5-16(6-4-15)27(22,23)19-8-11-24-12-9-19/h3-6,14,18H,7-13H2,1-2H3
- InChiKey: FVGLWZCHWVFUPJ-UHFFFAOYSA-N
Network
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Synonyms
- N-(2,2-dimethyltetrahydropyran-4-yl)-4-morpholinosulfonyl-benzenesulfonamide
- N-(2,2-dimethyl-4-tetrahydropyranyl)-4-morpholinosulfonylbenzenesulfonamide
- N-(2,2-dimethyloxan-4-yl)-4-morpholin-4-ylsulfonyl-benzenesulfonamide
- SMR000007534
- MLS000033357
- N-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-4-(morpholine-4-sulfonyl)-benzenesulfonamide
- ASN 06977363
Targets
Known targets for this compound
No curated genes were found associated with this compound
Predicted pathogen targets for this compound
By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model
Ranking Plot
Putative Targets List
| Species | Potential target | Raw | Global | Species |
|---|---|---|---|---|
| Echinococcus multilocularis | heat shock protein 90 | 0.0099 | 0.8565 | 0.7479 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Leishmania major | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | heat shock protein 85, putative | 0.0099 | 0.8565 | 0.8565 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | ketoacyl reductase | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0106 | 1 | 1 |
| Leishmania major | oxidoreductase-like protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | heat shock protein, putative | 0.0079 | 0.4308 | 0.4018 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | retinol dehydrogenase 11 | 0.0106 | 1 | 1 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Treponema pallidum | heat shock protein 90 | 0.0079 | 0.4308 | 0.5 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | heat shock protein, putative | 0.0079 | 0.4308 | 0.4018 |
| Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | oxidoreductase | 0.0106 | 1 | 1 |
| Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Entamoeba histolytica | short chain dehydrogenase family protein | 0.0106 | 1 | 1 |
| Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0106 | 1 | 0.5 |
| Mycobacterium ulcerans | oxidoreductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | heat shock protein 85, putative | 0.0099 | 0.8565 | 0.8565 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible oxidoreductase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | retinal dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | heat shock protein 90 | 0.0099 | 0.8565 | 0.7479 |
| Entamoeba histolytica | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | dehydrogenase | 0.0106 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0106 | 1 | 1 |
| Echinococcus granulosus | heat shock protein | 0.0099 | 0.8565 | 0.7479 |
| Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0106 | 1 | 1 |
| Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0106 | 1 | 1 |
| Giardia lamblia | Hypothetical protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | carbonyl reductase | 0.0106 | 1 | 1 |
| Entamoeba histolytica | short chain dehydrogenase family protein | 0.0106 | 1 | 1 |
| Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, putative | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0106 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | heat shock protein 90, putative | 0.0079 | 0.4308 | 0.4308 |
| Brugia malayi | hypothetical protein | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium leprae | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | heat shock protein 85, putative | 0.0099 | 0.8565 | 0.8565 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | heat shock protein, putative | 0.0099 | 0.8565 | 0.8492 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | short chain dehydrogenase/reductase, putative | 0.0106 | 1 | 1 |
| Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Mycobacterium ulcerans | ketoacyl reductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0106 | 1 | 1 |
| Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase | 0.0106 | 1 | 1 |
| Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Giardia lamblia | Short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | heat shock protein 90, putative | 0.0099 | 0.8565 | 0.8565 |
| Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0106 | 1 | 1 |
| Echinococcus granulosus | oxidoreductase | 0.0106 | 1 | 1 |
| Toxoplasma gondii | carbonyl reductase 1, putative | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Schistosoma mansoni | carbonyl reductase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | carbonyl reductase | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0106 | 1 | 1 |
| Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0106 | 1 | 1 |
| Echinococcus granulosus | hypothetical protein | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0099 | 0.8565 | 0.7479 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0106 | 1 | 1 |
| Plasmodium falciparum | heat shock protein 90 | 0.0099 | 0.8565 | 0.8492 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | oxidoreductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Leishmania major | short chain dehydrogenase/reductase, putative | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Leishmania major | short chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | retinol dehydrogenase 11 | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | short chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Brugia malayi | Retinol dehydrogenase 12 | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0106 | 1 | 1 |
| Plasmodium vivax | steroid dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0106 | 1 | 1 |
| Plasmodium falciparum | steroid dehydrogenase, putative | 0.0106 | 1 | 1 |
| Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | dehydrogenase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Possible oxidoreductase | 0.0106 | 1 | 1 |
| Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | pteridine reductase 1 | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | heat shock protein 85, putative | 0.0079 | 0.4308 | 0.4308 |
| Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Echinococcus granulosus | hypothetical protein | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0106 | 1 | 1 |
| Echinococcus granulosus | WW domain containing oxidoreductase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, putative | 0.0106 | 1 | 1 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | heat shock protein | 0.0099 | 0.8565 | 0.7479 |
| Leishmania major | dehydrogenase-like protein | 0.0106 | 1 | 1 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0106 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | heat shock protein, putative | 0.0079 | 0.4308 | 0.4018 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0106 | 1 | 1 |
| Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | conserved hypothetical protein | 0.0106 | 1 | 1 |
| Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | transient receptor potential cation channel | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | Heat shock protein 83, putative | 0.0099 | 0.8565 | 0.8565 |
| Onchocerca volvulus | Sepiapterin reductase homolog | 0.0106 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0106 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Brugia malayi | dehydrogenases, short chain protein 9 | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | dehydrogenase | 0.0106 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Brugia malayi | dehydrogenases, short chain protein 2 | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0106 | 1 | 0.5 |
| Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0106 | 1 | 1 |
| Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Echinococcus multilocularis | steroid dehydrogenase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Giardia lamblia | Reductase, putative | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0106 | 1 | 1 |
| Onchocerca volvulus | 0.0106 | 1 | 0.5 | |
| Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0106 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | ketoacyl reductase | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | short chain dehydrogenase-like protein | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0106 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0106 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Plasmodium vivax | hypothetical protein, conserved | 0.0106 | 1 | 1 |
| Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0106 | 1 | 1 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0106 | 1 | 1 |
| Trypanosoma brucei | oxidoreductase-like protein | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0106 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0106 | 1 | 1 |
| Leishmania major | heat shock protein 83-1 | 0.0099 | 0.8565 | 0.7479 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0106 | 1 | 1 |
Activities
No activities found for this compound.
Phenotypes
Whole-cell/tissue/organism interactions
We have no records of whole-cell/tissue assays done with this compound
What does this mean?
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Annotated phenotypes:
We have no manually annotated phenotypes for this drug.
What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by
drugs, or by genetic manipulation of cells (e.g. gene knockouts or
knockdowns) is manually curated from the literature. These
descriptions help to describe the potential of the target for drug
development. If no information is available for this gene or if the
information is incomplete, this may mean that i) the papers
containing this information either appeared after the curation
effort for this organism was carried out or they were inadvertently
missed by curators; or that ii) the curation effort for this
organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
External resources for this compound
- ChEMBL: CHEMBL1525850
Bibliographic References
No literature references available for this target.
If you have references for this compound, please enter them in a user comment (below) or Contact us.