Detailed information for compound 1430778

Basic information

Technical information
  • TDR Targets ID: 1430778
  • Name: IDI1_015168
  • MW: 346.328 | Formula: C13H13F3N4O2S
  • H donors: 1 H acceptors: 5 LogP: 2.51 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1nc(ncc1S(=O)(=O)c1ccc(cn1)C(F)(F)F)C(C)C
  • InChi: 1S/C13H13F3N4O2S/c1-7(2)12-19-6-9(11(17)20-12)23(21,22)10-4-3-8(5-18-10)13(14,15)16/h3-7H,1-2H3,(H2,17,19,20)
  • InChiKey: GCAYBTXVNSFGMD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Maybridge3_003781
  • 2-isopropyl-5-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}pyrimidin-4-amine
  • MLS000860710
  • SMR000459494
  • ZINC00149255

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0241 0.1086 0.2291
Echinococcus granulosus tyrosine protein kinase ABL1 0.0006 0.0009 0.0009
Plasmodium falciparum serine repeat antigen 1 0.0241 0.1086 0.2291
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0241 0.1086 0.2291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Plasmodium falciparum serine repeat antigen 6 0.0241 0.1086 0.2291
Entamoeba histolytica SH2 domain containing protein 0.0004 0 0.0001
Giardia lamblia Encystation-specific protease 0.0241 0.1086 0.2826
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0006 0.0009 0.0009
Brugia malayi hypothetical protein 0.0009 0.0023 0.0023
Schistosoma mansoni poly [ADP-ribose] polymerase 0.001 0.0031 0.0031
Brugia malayi Cation transporter family protein 0.0019 0.0069 0.0069
Brugia malayi cathepsin Z-like cysteine proteinase 0.0241 0.1086 0.1086
Giardia lamblia Hypothetical protein 0.0241 0.1086 0.2826
Loa Loa (eye worm) phosphatidylinositol kinase 0.0004 0.0000082046 0.0000082046
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0008 0.0018 0.0018
Brugia malayi Sex muscle abnormal protein 5 0.0007 0.0017 0.0017
Leishmania major phosphatidylinositol kinase related protein, putative 0.0004 0.0000082046 0.0000037917
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.001 0.0031 0.0031
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0004 0.0000082046 0.0000082046
Schistosoma mansoni cathepsin C 0.0241 0.1086 0.1086
Plasmodium falciparum cysteine proteinase falcipain 1 0.0564 0.2568 0.5416
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0004 0.0000082046 0.0000017976
Schistosoma mansoni sorting nexin 0.0004 0.000006407 0.000006407
Brugia malayi cathepsin F-like cysteine proteinase 0.0323 0.1465 0.1465
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0009 0.0026 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0023 0.0023
Onchocerca volvulus Fxna peptidase homolog 0.0018 0.0067 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0004 0.0000082046 0.0000037917
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0026 0.0026
Brugia malayi Peptidase family M28 containing protein 0.0115 0.0509 0.0509
Echinococcus granulosus nAChR subunit 0.0019 0.0069 0.0069
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0009 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1038 0.4741 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.007 0.0146
Leishmania major hypothetical protein, conserved 0.0018 0.0067 0.0142
Echinococcus granulosus cathepsin l cysteine peptidase 0.1038 0.4741 0.4741
Brugia malayi hypothetical protein 0.0004 0.0002 0.0002
Trypanosoma cruzi cruzipain precursor, putative 0.1038 0.4741 0.4741
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.007 0.0146
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Onchocerca volvulus 0.0019 0.0069 0.0146
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0038
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.007 0.0146
Brugia malayi fibroinase precursor 0.0241 0.1086 0.1086
Echinococcus multilocularis cathepsin b 0.2185 1 1
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0069 0.0069
Echinococcus multilocularis 0.0004 0.0000082046 0.0000082046
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase shark 0.0006 0.001 0.001
Brugia malayi Myosin tail family protein 0.0004 0.000006407 0.000006407
Brugia malayi Variant SH3 domain containing protein 0.0007 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Loa Loa (eye worm) hypothetical protein 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) hypothetical protein 0.0007 0.0017 0.0017
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0069 0.0069
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0069 0.0069
Brugia malayi photoreceptor-specific nuclear receptor 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0004 0.0000082046 0.0000082046
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0004 0.0000082046 0.0000037917
Echinococcus granulosus intersectin 2 0.0004 0.000006407 0.000006407
Entamoeba histolytica cysteine proteinase, putative 0.1038 0.4741 1
Trypanosoma cruzi cysteine peptidase, putative 0.1038 0.4741 0.4741
Brugia malayi Papain family cysteine protease containing protein 0.0564 0.2568 0.2568
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Echinococcus multilocularis poly (ADP ribose) polymerase 0.001 0.0031 0.0031
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0009 0.0023 0.0023
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.001 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0564 0.2568 0.5416
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0004 0.0000082046 0.0000082046
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0009 0.0026 0.0026
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0004 0.000006407 0.000006407
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0009 0.0023 0.0023
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0842 0.3843 0.3843
Onchocerca volvulus Putative nachr subunit 0.0019 0.0069 0.0146
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0241 0.1086 0.2291
Onchocerca volvulus 0.0006 0.0009 0.0019
Plasmodium falciparum cysteine proteinase falcipain 3 0.1038 0.4741 1
Onchocerca volvulus 0.001 0.003 0.0063
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0564 0.2568 0.2568
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0018 0.0018
Echinococcus granulosus cathepsin L cysteine protease 0.0564 0.2568 0.2568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0013 0.0027
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0004 0.0002 0.0002
Echinococcus granulosus src region 0.0004 0.000006407 0.000006407
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.007 0.0146
Trypanosoma cruzi cysteine peptidase, putative 0.1038 0.4741 0.4741
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0009
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1038 0.4741 0.4741
Echinococcus multilocularis SAM domain containing protein 0.0006 0.0013 0.0013
Trypanosoma brucei poly(adp-ribose) polymerase 0.001 0.0031 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0006 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Entamoeba histolytica cysteine proteinase, putative 0.1038 0.4741 1
Leishmania major cysteine peptidase A (CPA) 0.1038 0.4741 1
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0008 0.0018 0.0018
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0241 0.1086 0.2291
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0715 0.3259 0.6875
Schistosoma mansoni Fxna peptidase (M28 family) 0.0018 0.0067 0.0067
Echinococcus multilocularis cathepsin b 0.2185 1 1
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0269 0.1218 0.1218
Echinococcus granulosus cysteine protease 0.0564 0.2568 0.2568
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0009 0.0023 0.0023
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0004 0.0000082046 0.0000082046
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0004 0 0.0001
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0007 0.0017 0.0017
Onchocerca volvulus 0.001 0.003 0.0063
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0115 0.0509 0.0509
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0009 0.0026 0.0026
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0011 0.0032 0.0067
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0006 0.0009 0.0009
Echinococcus granulosus FTZ F1 alpha 0.0008 0.0018 0.0018
Echinococcus multilocularis cysteine protease 0.1038 0.4741 0.4741
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.007 0.007
Brugia malayi Cathepsin L-like precursor 0.1038 0.4741 0.4741
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0018 0.0018
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0715 0.3259 0.3259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0015 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0564 0.2568 0.5416
Echinococcus multilocularis cathepsin L cysteine protease 0.1038 0.4741 0.4741
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0004 0.0000082046 0.0000082046
Schistosoma mansoni acetylcholine receptor-related 0.0009 0.0023 0.0023
Onchocerca volvulus 0.0019 0.0069 0.0146
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.007 0.007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0008 0.0018 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.0079
Brugia malayi Cathepsin L-like precursor 0.0323 0.1465 0.1465
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0069 0.0069
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0241 0.1086 0.1086
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0004 0.0000082046 0.0000037917
Schistosoma mansoni tyrosine kinase 0.0006 0.001 0.001
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.007 0.007
Echinococcus granulosus Spectrin alpha actinin 0.0004 0.000006407 0.000006407
Plasmodium vivax vivapain-2 0.1038 0.4741 1
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0002
Brugia malayi Variant SH3 domain containing protein 0.0004 0.000006407 0.000006407
Schistosoma mansoni Dab2-interacting protein-like 0.0004 0.000006407 0.000006407
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0004 0.0000082046 0.0000037917
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0011 0.0032 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0018 0.0018
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0018 0.0018
Onchocerca volvulus Protein ultraspiracle homolog 0.0008 0.0018 0.0039
Loa Loa (eye worm) leucyl aminopeptidase 0.0018 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Plasmodium falciparum serine repeat antigen 4 0.0241 0.1086 0.2291
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0004 0.0000082046 0.0000037917
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Loa Loa (eye worm) tnks protein 0.0066 0.0286 0.0286
Schistosoma mansoni cathepsin F (C01 family) 0.1038 0.4741 0.4741
Brugia malayi Peripheral plasma membrane protein CASK 0.0004 0.000006407 0.000006407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0241 0.1086 0.2291
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0038 0.0079
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0009 0.0026 0.0026
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0004 0.0000082046 0.0000082046
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0018 0.0018
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0004 0.000006407 0.000006407
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1038 0.4741 0.4741
Trypanosoma cruzi major cysteine proteinase, putative 0.0241 0.1086 0.1086
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0008 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Plasmodium vivax vivapain-3 0.0564 0.2568 0.5416
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.007 0.0069
Plasmodium falciparum serine repeat antigen 5 0.0241 0.1086 0.2291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Trypanosoma cruzi cysteine peptidase, putative 0.0323 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0018 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0006 0.0013 0.0013
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0009 0.0026 0.0026
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0269 0.1218 0.1218
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0241 0.1086 0.1086
Echinococcus granulosus growth factor receptor bound protein 2 0.0007 0.0017 0.0017
Plasmodium falciparum protein kinase, putative 0.0008 0.0022 0.0045
Echinococcus granulosus tyrosine protein kinase Lyn 0.0009 0.0026 0.0026
Plasmodium falciparum serine repeat antigen 9 0.0241 0.1086 0.2291
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0323 0.1465 0.1465
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2185 1 1
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0004 0.0000082046 0.0000082046
Trypanosoma cruzi cysteine peptidase, putative 0.0564 0.2568 0.2568
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.007 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0715 0.3259 0.6875
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0032 0.0032
Brugia malayi Fes/CIP4 homology domain containing protein 0.0004 0.000006407 0.000006407
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0006 0.0013 0.0013
Schistosoma mansoni sarm1 0.0006 0.0013 0.0013
Giardia lamblia Hypothetical protein 0.0241 0.1086 0.2826
Schistosoma mansoni tyrosine kinase 0.0009 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Entamoeba histolytica hypothetical protein 0.0004 0.0000082046 0.0000037917
Onchocerca volvulus 0.0019 0.0069 0.0146
Mycobacterium tuberculosis Conserved protein 0.0018 0.0067 1
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0004 0.0000082046 0.0000037917
Echinococcus multilocularis growth factor receptor bound protein 2 0.0007 0.0017 0.0017
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1038 0.4741 0.4741
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0009 0.0023 0.0023
Brugia malayi Cation transporter family protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Schistosoma mansoni cell polarity protein 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0008 0.0018 0.0018
Brugia malayi hypothetical protein 0.0009 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0069 0.0069
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Onchocerca volvulus 0.1038 0.4741 1
Echinococcus multilocularis cysteine protease 0.1038 0.4741 0.4741
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0004 0.0000082046 0.0000037917
Schistosoma mansoni hypothetical protein 0.0004 0.000006407 0.000006407
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.001 0.0031 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0067 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Echinococcus multilocularis transfer RNA-Ala 0.0004 0.000006407 0.000006407
Toxoplasma gondii FATC domain-containing protein 0.0011 0.0032 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0018 0.0018
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0004 0.0000082046 0.0000037917
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Echinococcus granulosus epidermal growth factor receptor 0.0081 0.0356 0.0356
Trypanosoma cruzi cruzipain precursor, putative 0.0323 0.1465 0.1465
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Brugia malayi Guanylate kinase family protein 0.0004 0.000006407 0.000006407
Brugia malayi nuclear receptor RXR 0.0004 0.0002 0.0002
Plasmodium vivax vivapain-1 0.0564 0.2568 0.5416
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.007 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Onchocerca volvulus Fxna peptidase homolog 0.0018 0.0067 0.0142
Entamoeba histolytica cysteine proteinase 2 0.0564 0.2568 0.5416
Onchocerca volvulus 0.0004 0 0.0001
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0012 0.0038 0.0079
Leishmania major hypothetical protein, unknown function 0.0004 0.0000082046 0.0000037917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0004 0.000006407 0.000006407
Brugia malayi Tnks protein 0.0072 0.0314 0.0314
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0009 0.0026 0.0026
Loa Loa (eye worm) thyroid receptor interactor 0.0004 0.000006407 0.000006407
Brugia malayi WGR domain containing protein 0.001 0.0031 0.0031
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0004 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0018 0.0018
Brugia malayi steroid hormone receptor 0.0008 0.0018 0.0018
Plasmodium vivax serine-repeat antigen (SERA) 0.0241 0.1086 0.2291
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0013 0.0027
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0303 0.1374 0.1374
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0004 0.0000082046 0.0000017976
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0018 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0006 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0008 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.007 0.0146
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0008 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Schistosoma mansoni C-fyn 0.0004 0.000006407 0.000006407
Echinococcus multilocularis Spectrin alpha actinin 0.0004 0.000006407 0.000006407
Schistosoma mansoni cathepsin F (C01 family) 0.0715 0.3259 0.3259
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0241 0.1086 0.2826
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0009 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0241 0.1086 0.1086
Loa Loa (eye worm) hypothetical protein 0.0241 0.1086 0.1086
Entamoeba histolytica cysteine protease, putative 0.0241 0.1086 0.2291
Brugia malayi Protein kinase domain containing protein 0.0006 0.0009 0.0009
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0007 0.0017 0.0017
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0018 0.0018
Echinococcus multilocularis serine protein kinase ATM 0.0011 0.0032 0.0032
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.001 0.003 0.003
Schistosoma mansoni tyrosine kinase 0.0009 0.0026 0.0026
Schistosoma mansoni fkbp-rapamycin associated protein 0.0011 0.0032 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0004 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.001 0.0031 0.0065
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0241 0.1086 0.2826
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0004 0.0000082046 0.0000082046
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0241 0.1086 0.2291
Toxoplasma gondii peptidase, M28 family protein 0.0018 0.0067 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Onchocerca volvulus Cathepsin L homolog 0.0241 0.1086 0.2291
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Echinococcus multilocularis cathepsin L 0.0241 0.1086 0.1086
Echinococcus granulosus cathepsin L 0.0564 0.2568 0.2568
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0004 0.0000082046 0.0000017976
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0008 0.0018 0.0018
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0004 0.0000082046 0.0000082046
Trypanosoma brucei cysteine peptidase C (CPC) 0.0842 0.3843 0.8106
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0018 0.0018
Echinococcus granulosus cathepsin b 0.2185 1 1
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0004 0.000006407 0.000006407
Onchocerca volvulus 0.0019 0.0069 0.0146
Brugia malayi Papain family cysteine protease containing protein 0.1038 0.4741 0.4741
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0069 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0241 0.1086 0.1086
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0069 0.0069
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Onchocerca volvulus 0.1038 0.4741 1
Brugia malayi Neurabin protein 1 0.0006 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0241 0.1086 0.2291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi Liprin-alpha 2 0.0006 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0008 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) ctsf protein 0.1038 0.4741 0.4741
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0026 0.0026
Plasmodium falciparum tyrosine kinase-like protein 0.0008 0.0022 0.0045
Schistosoma mansoni nck2/grb4 0.0007 0.0017 0.0017
Echinococcus multilocularis liprin alpha 2 0.0006 0.0013 0.0013
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0241 0.1086 0.2291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0241 0.1086 0.2291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Onchocerca volvulus Cathepsin F homolog 0.1038 0.4741 1
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Loa Loa (eye worm) phosphatidylinositol 3 0.0004 0.0000082046 0.0000082046
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0004 0.0000082046 0.0000037917
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0241 0.1086 0.2291
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0026 0.0026
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0004 0.0002 0.0002
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0842 0.3843 0.8106
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0008 0.0018 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0715 0.3259 0.6875
Brugia malayi Variant SH3 domain containing protein 0.0004 0.000006407 0.000006407
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.001 0.0031 0.0031
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0069 0.0069
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0011 0.0032 0.0032
Leishmania major glutaminyl cyclase, putative 0.0018 0.0067 0.0142
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.001 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0008 0.0018 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0008 0.0018 0.0018
Entamoeba histolytica cysteine proteinase 1, putative 0.0564 0.2568 0.5416
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0069 0.0069
Onchocerca volvulus Glutaminyl cyclase homolog 0.0115 0.0509 0.1074
Entamoeba histolytica cysteine proteinase, putative 0.0564 0.2568 0.5416
Loa Loa (eye worm) hypothetical protein 0.0323 0.1465 0.1465
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Giardia lamblia Cysteine protease 0.0241 0.1086 0.2826
Echinococcus granulosus expressed protein 0.0004 0.000006407 0.000006407
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0241 0.1086 0.2826
Brugia malayi FAT domain containing protein 0.0008 0.0021 0.0021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0004 0.0000082046 0.0000082046
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0069 0.0069
Schistosoma mansoni tyrosine kinase 0.0049 0.0207 0.0207
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.007 0.0069
Brugia malayi Src substrate cortactin 0.0004 0.000006407 0.000006407
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0004 0.0000082046 0.0000082046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0241 0.1086 0.2291
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0069 0.0069
Echinococcus multilocularis thyroid hormone receptor alpha 0.0008 0.0018 0.0018
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0241 0.1086 0.1086
Schistosoma mansoni formin binding protein and related proteins 0.0004 0.000006407 0.000006407
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0018 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0241 0.1086 0.1086
Onchocerca volvulus 0.0004 0 0.0001
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Giardia lamblia Cathepsin L precursor 0.0241 0.1086 0.2826
Loa Loa (eye worm) TK/ABL protein kinase 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Brugia malayi coiled-coil like protein 1 0.0006 0.0013 0.0013
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0564 0.2568 0.2568
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.0018 0.0067 0.5
Schistosoma mansoni tyrosine kinase 0.0081 0.0356 0.0356
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0004 0.0000082046 0.0000037917
Brugia malayi cathepsin L-like precursor 0.0715 0.3259 0.3259
Schistosoma mansoni hypothetical protein 0.0006 0.0013 0.0013
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.001 0.003 0.003
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0069 0.0069
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0006 0.0013 0.0013
Onchocerca volvulus 0.1038 0.4741 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.007 0.007
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0111 0.049 0.049
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0023 0.0023
Loa Loa (eye worm) TK protein kinase 0.0006 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0026 0.0026
Brugia malayi cathepsin Z-like cysteine proteinase 0.0241 0.1086 0.1086
Echinococcus multilocularis tyrosine protein kinase Abl 0.0009 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Schistosoma mansoni tyrosine kinase 0.0079 0.0348 0.0348
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0004 0.0000082046 0.0000082046
Brugia malayi Papain family cysteine protease containing protein 0.0564 0.2568 0.2568
Brugia malayi cathepsin L-like cysteine proteinase 0.0241 0.1086 0.1086
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0004 0.000006407 0.000006407
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0004 0.0000082046 0.0000082046
Brugia malayi FXNA 0.0018 0.0067 0.0067
Brugia malayi Protein kinase domain containing protein 0.0006 0.0009 0.0009
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) hypothetical protein 0.0064 0.0277 0.0277
Leishmania major hypothetical protein, conserved 0.0098 0.0432 0.091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0069
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.007 0.007
Loa Loa (eye worm) GABA receptor subunit 0.001 0.003 0.003
Schistosoma mansoni dreadlocks/dock 0.0004 0.000006407 0.000006407
Trypanosoma cruzi glutaminyl cyclase, putative 0.0018 0.0067 0.0067
Entamoeba histolytica hypothetical protein 0.0004 0.0000082046 0.0000037917
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0241 0.1086 0.1086
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0241 0.1086 0.2291
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Brugia malayi hypothetical protein 0.0006 0.0013 0.0013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0004 0.0000082046 0.0000082046
Brugia malayi Tyrosine-protein kinase abl-1 0.0009 0.0026 0.0026
Brugia malayi hypothetical protein 0.0009 0.0023 0.0023
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2185 1 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0006 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Trypanosoma cruzi cysteine proteinase, putative 0.0564 0.2568 0.2568
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.001 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Echinococcus granulosus cathepsin L cysteine proteinase 0.1038 0.4741 0.4741
Echinococcus multilocularis liprin beta 1 0.0006 0.0013 0.0013
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0011 0.0032 0.0032
Loa Loa (eye worm) phosphatidylinositol 3 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0008 0.0018 0.0018
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0004 0.0000082046 0.0000082046
Onchocerca volvulus 0.0006 0.0009 0.0019
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0008 0.0018 0.0018
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0081 0.0356 0.0356
Schistosoma mansoni hypothetical protein 0.0004 0.000006407 0.000006407
Entamoeba histolytica cysteine proteinase, putative 0.0564 0.2568 0.5416
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0011 0.0032 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Schistosoma mansoni hypothetical protein 0.0008 0.0021 0.0021
Echinococcus granulosus stromal interaction molecule 1 0.0006 0.0013 0.0013
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0008 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Schistosoma mansoni run and tbc1 domain containing 0.0004 0.000006407 0.000006407
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0004 0.000006407 0.000006407
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0013 0.0027
Echinococcus multilocularis nAChR subunit 0.001 0.003 0.003
Plasmodium vivax unspecified product 0.0564 0.2568 0.5416
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0006 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Schistosoma mansoni growth factor receptor-bound protein 0.0007 0.0017 0.0017
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0009 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0006 0.0013 0.0013
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0241 0.1086 0.1086
Echinococcus granulosus liprin beta 1 0.0006 0.0013 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2185 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi hypothetical protein 0.0006 0.0013 0.0013
Giardia lamblia Cathepsin B precursor 0.0241 0.1086 0.2826
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Plasmodium vivax vivapain-2 0.1038 0.4741 1
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0115 0.0509 0.0509
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Echinococcus granulosus Sterile alpha motif SAM 0.0006 0.0013 0.0013
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0069 0.0069
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0006 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0008 0.0018 0.0018
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0007 0.0015 0.0015
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.007 0.0146
Echinococcus granulosus serine protein kinase ATM 0.0011 0.0032 0.0032
Loa Loa (eye worm) cysteine protease 0.1038 0.4741 0.4741
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0241 0.1086 0.2291
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0241 0.1086 0.2291
Plasmodium vivax unspecified product 0.0241 0.1086 0.2291
Onchocerca volvulus 0.0006 0.0013 0.0027
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0018 0.0067 0.0067
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.007 0.0146
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.007 0.0069
Schistosoma mansoni nAChR subunit 0.0009 0.0023 0.0023
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0031
Onchocerca volvulus 0.0241 0.1086 0.2291
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Onchocerca volvulus 0.1038 0.4741 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1038 0.4741 1
Plasmodium vivax unspecified product 0.0323 0.1465 0.309
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0004 0.0000082046 0.0000082046
Giardia lamblia Cathepsin B precursor 0.0842 0.3843 1
Schistosoma mansoni dynamin-associated protein 0.0004 0.000006407 0.000006407
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Echinococcus granulosus nAChR subunit 0.001 0.003 0.003
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Schistosoma mansoni coup transcription factor 0.0008 0.0018 0.0018
Schistosoma mansoni cathepsin F (C01 family) 0.1038 0.4741 0.4741
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0241 0.1086 0.2291
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.001 0.0031 0.0031
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0067 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0069 0.0069
Toxoplasma gondii preprocathepsin c precursor, putative 0.0241 0.1086 0.2291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0564 0.2568 0.2568
Loa Loa (eye worm) hypothetical protein 0.0008 0.0021 0.0021
Trypanosoma cruzi major cysteine proteinase, putative 0.0241 0.1086 0.1086
Onchocerca volvulus 0.0006 0.0009 0.0019
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0004 0.0000082046 0.0000017976
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0009 0.0023 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0564 0.2568 0.2568
Loa Loa (eye worm) hypothetical protein 0.0323 0.1465 0.1465
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1038 0.4741 1
Entamoeba histolytica hypothetical protein 0.0011 0.0032 0.0067
Schistosoma mansoni hypothetical protein 0.0006 0.0013 0.0013
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0004 0.0000082046 0.0000037917
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0069
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.007 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi Variant SH3 domain containing protein 0.0007 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0004 0.0000082046 0.0000037917
Entamoeba histolytica zinc finger protein, putative 0.001 0.0031 0.0065
Loa Loa (eye worm) guanylate kinase 0.0004 0.000006407 0.000006407
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0241 0.1086 0.2291
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0008 0.0018 0.0018
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0012 0.0038 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0241 0.1086 0.2291
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.007 0.007
Giardia lamblia Cathepsin L-like protease 0.0241 0.1086 0.2826
Echinococcus multilocularis tyrosine protein kinase shark 0.0006 0.001 0.001
Echinococcus multilocularis Zinc finger, PHD finger 0.0004 0.0000082046 0.0000082046
Onchocerca volvulus 0.0009 0.0023 0.0049
Loa Loa (eye worm) phosphatidylinositol 3 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0069 0.0069
Brugia malayi Protein kinase domain containing protein 0.0049 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2185 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0044
Mycobacterium ulcerans hypothetical protein 0.0018 0.0067 0.5
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Entamoeba histolytica cysteine protease, putative 0.0241 0.1086 0.2291
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0004 0.0000082046 0.0000037917
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Giardia lamblia Cysteine protease 0.0241 0.1086 0.2826
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0069 0.0069
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Schistosoma mansoni nicalin (M28 family) 0.0018 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.1086 0.2291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0004 0.0000082046 0.0000082046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0241 0.1086 0.2291
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0018 0.0067 0.0142
Echinococcus granulosus cathepsin b 0.2185 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Toxoplasma gondii cathepsin CPC1 0.0241 0.1086 0.2291
Giardia lamblia Cysteine protease 0.0241 0.1086 0.2826
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.007 0.0069
Loa Loa (eye worm) TK/INSR protein kinase 0.0049 0.0207 0.0207
Brugia malayi Nuclear hormone receptor-like 1 0.0004 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0018 0.0018
Onchocerca volvulus Cathepsin L homolog 0.1038 0.4741 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi hypothetical protein 0.0009 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0241 0.1086 0.2291
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0004 0.0000082046 0.0000082046
Echinococcus multilocularis expressed protein 0.0004 0.000006407 0.000006407
Entamoeba histolytica cysteine proteinase, putative 0.0564 0.2568 0.5416
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Entamoeba histolytica hypothetical protein 0.0004 0.0000082046 0.0000037917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0006 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Schistosoma mansoni apoptosis stimulating of P53 0.0004 0.0000064102 0.0000064102
Onchocerca volvulus 0.0018 0.0067 0.0142
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0004 0.0002 0.0002
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0004 0.000006407 0.000006407
Schistosoma mansoni tyrosine kinase 0.0009 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Brugia malayi Papain family cysteine protease containing protein 0.0241 0.1086 0.1086
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0004 0.0000064102 0.0000064102
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0241 0.1086 0.1086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Plasmodium falciparum serine repeat antigen 8 0.0241 0.1086 0.2291
Brugia malayi ecdysteroid receptor 0.0008 0.0018 0.0018
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0006 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.2185 1 1
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0241 0.1086 0.1086
Echinococcus granulosus tyrosine protein kinase Src42A 0.0009 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0002
Giardia lamblia Cysteine protease 0.0241 0.1086 0.2826
Giardia lamblia Cathepsin B precursor 0.0241 0.1086 0.2826
Loa Loa (eye worm) phosphatidylinositol 3 0.0004 0.0000082046 0.0000082046
Brugia malayi Spectrin alpha chain 0.0004 0.000006407 0.000006407
Toxoplasma gondii hypothetical protein 0.0018 0.0067 0.0142
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0004 0.0000082046 0.0000017976
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0015 0.0033
Echinococcus multilocularis intersectin 2 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Echinococcus multilocularis nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0241 0.1086 0.2291
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trypanosoma cruzi glutaminyl cyclase, putative 0.0018 0.0067 0.0067
Schistosoma mansoni poly [ADP-ribose] polymerase 0.001 0.0031 0.0031
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0004 0.000006407 0.000006407
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0004 0.0000082046 0.0000082046
Onchocerca volvulus 0.1038 0.4741 1
Echinococcus granulosus nostrin 0.0004 0.000006407 0.000006407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0069
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0004 0.0000082046 0.0000037917
Plasmodium vivax tyrosine kinase-like protein, putative 0.0008 0.0022 0.0045
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0842 0.3843 0.3843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0241 0.1086 0.2291
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0004 0.0000082046 0.0000082046
Echinococcus granulosus epidermal growth factor receptor 0.015 0.0673 0.0673
Onchocerca volvulus 0.0715 0.3259 0.6875
Loa Loa (eye worm) steroid hormone receptor 0.0008 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0241 0.1086 0.2291
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0009 0.0026 0.0026
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1038 0.4741 1
Schistosoma mansoni neurotransmitter gated ion channel 0.001 0.003 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0069 0.0069
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.007 0.007
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0004 0.000006407 0.000006407
Brugia malayi cathepsin F-like cysteine proteinase 0.0241 0.1086 0.1086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Brugia malayi cathepsin L precursor 0.0241 0.1086 0.1086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Echinococcus multilocularis tankyrase 0.0072 0.0315 0.0315
Trypanosoma brucei glutaminyl cyclase, putative 0.0018 0.0067 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0008 0.0018 0.0018
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0004 0.000006407 0.000006407
Trypanosoma cruzi cysteine proteinase, putative 0.0564 0.2568 0.2568
Schistosoma mansoni eps8-related protein 0.0004 0.000006407 0.000006407
Brugia malayi nuclear receptor NHR-88 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0018 0.0018
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0004 0.000006407 0.000006407
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0008 0.0018 0.0018
Giardia lamblia Cathepsin L precursor 0.0241 0.1086 0.2826
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Brugia malayi Steroid receptor seven-up type 2 0.0008 0.0018 0.0018
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.1038 0.4741 0.4741
Echinococcus multilocularis tyrosine kinase 0.0006 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0009 0.0026 0.0026
Brugia malayi Variant SH3 domain containing protein 0.0004 0.000006407 0.000006407
Onchocerca volvulus 0.1038 0.4741 1
Giardia lamblia Cathepsin L-like protease 0.0241 0.1086 0.2826
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0241 0.1086 0.1086
Schistosoma mansoni tyrosine kinase 0.0079 0.0348 0.0348
Entamoeba histolytica hypothetical protein 0.0004 0.0000082046 0.0000037917
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0069 0.0069
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0004 0.0000082046 0.0000037917
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Echinococcus granulosus liprin alpha 2 0.0006 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0069 0.0069
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Giardia lamblia Cathepsin B precursor 0.0241 0.1086 0.2826
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0241 0.1086 0.2291
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0006 0.0013 0.0013
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.007 0.0146
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0004 0.0000082046 0.0000037917
Toxoplasma gondii cathepsin B 0.0842 0.3843 0.8106
Brugia malayi SH2 domain containing protein 0.0006 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0009 0.0009
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0069 0.0069
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0023 0.0023
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0004 0 0.0001
Giardia lamblia GTOR 0.0019 0.007 0.0181
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0004 0.0000082046 0.0000017976
Echinococcus multilocularis cathepsin L 0.0564 0.2568 0.2568
Schistosoma mansoni tyrosine kinase 0.015 0.0673 0.0673
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0069 0.0069
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0069 0.0069
Giardia lamblia Cathepsin L precursor 0.0241 0.1086 0.2826
Onchocerca volvulus Bile acid receptor homolog 0.0008 0.0018 0.0039
Entamoeba histolytica cysteine protease, putative 0.0241 0.1086 0.2291
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0069 0.0069
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0241 0.1086 0.1086
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0069 0.0069
Echinococcus granulosus ecdysone induced protein 78C 0.0008 0.0018 0.0018
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Brugia malayi leucyl aminopeptidase 0.0018 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Loa Loa (eye worm) hypothetical protein 0.0241 0.1086 0.1086
Brugia malayi WGR domain containing protein 0.001 0.0031 0.0031
Echinococcus multilocularis cathepsin L cysteine protease 0.1038 0.4741 0.4741
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0004 0.000006407 0.000006407
Echinococcus granulosus epidermal growth factor receptor kinase 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) p53BP2 0.0004 0.0000064102 0.0000064102
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0715 0.3259 0.3259
Echinococcus granulosus poly adp ribose polymerase 2 0.001 0.0031 0.0031
Giardia lamblia Cathepsin L precursor 0.0241 0.1086 0.2826
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0006 0.0013 0.0027
Brugia malayi Cathepsin L-like precursor 0.1038 0.4741 0.4741
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0007 0.0017 0.0017
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0115 0.0509 0.0509
Onchocerca volvulus 0.1038 0.4741 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0006 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0004 0.0000082046 0.0000082046
Schistosoma mansoni growth factor receptor-bound protein 0.0007 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0241 0.1086 0.2291
Giardia lamblia Cathepsin B precursor 0.0842 0.3843 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Onchocerca volvulus 0.0004 0 0.0001
Echinococcus granulosus cathepsin l1 0.0715 0.3259 0.3259
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0009 0.0023 0.0023
Plasmodium falciparum serine repeat antigen 7 0.0241 0.1086 0.2291
Entamoeba histolytica hypothetical protein 0.001 0.0031 0.0065
Onchocerca volvulus 0.0009 0.0023 0.0049
Entamoeba histolytica cysteine protease, putative 0.0241 0.1086 0.2291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Echinococcus granulosus insulin receptor 0.0049 0.0207 0.0207
Entamoeba histolytica protein kinase, putative 0.0004 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Giardia lamblia Cathepsin L precursor 0.0241 0.1086 0.2826
Loa Loa (eye worm) cathepsin B 0.0842 0.3843 0.3843
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.001 0.0031 0.0031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0004 0.0000082046 0.0000082046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0842 0.3843 0.8106
Schistosoma mansoni sorbin 0.0004 0.000006407 0.000006407
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.007 0.0146
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0241 0.1086 0.2291
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0006 0.0009 0.0019
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0004 0.0000082046 0.0000082046
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.007 0.0069
Brugia malayi Cathepsin L-like precursor 0.0715 0.3259 0.3259
Schistosoma mansoni tyrosine kinase 0.0081 0.0356 0.0356
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0008 0.0018 0.0018
Brugia malayi SRC-1 0.0009 0.0026 0.0026
Schistosoma mansoni cathepsin B (C01 family) 0.0241 0.1086 0.1086
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0067 0.0142
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Brugia malayi Protein kinase domain containing protein 0.0006 0.0009 0.0009
Echinococcus multilocularis nostrin 0.0004 0.000006407 0.000006407
Brugia malayi SH2 domain containing protein 0.0006 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase Srms 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0241 0.1086 0.2291
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0011 0.0032 0.0032
Echinococcus granulosus c src tyrosine kinase 0.0009 0.0026 0.0026
Schistosoma mansoni tyrosine kinase 0.0079 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0018 0.0018
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0009 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.0006 0.0009 0.0009
Schistosoma mansoni acetylcholine receptor subunit beta 0.0009 0.0023 0.0023
Giardia lamblia Cathepsin B precursor 0.0241 0.1086 0.2826
Brugia malayi Cation transporter family protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Brugia malayi hypothetical protein 0.0009 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.001 0.0031 0.0065
Plasmodium vivax serine-repeat antigen (SERA) 0.0241 0.1086 0.2291
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0032 0.0032
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0026 0.0026
Loa Loa (eye worm) fibroinase 0.1038 0.4741 0.4741
Schistosoma mansoni cathepsin s 0.0323 0.1465 0.1465
Giardia lamblia Cathepsin B precursor 0.0241 0.1086 0.2826
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Brugia malayi SH3 domain containing protein 0.0004 0.000006407 0.000006407
Onchocerca volvulus 0.0006 0.0013 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0241 0.1086 0.2291
Entamoeba histolytica cysteine protease, putative 0.1038 0.4741 1
Loa Loa (eye worm) SRC-1 0.0009 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0009 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0241 0.1086 0.2291
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0241 0.1086 0.2291
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0004 0 0.0001
Onchocerca volvulus 0.0004 0 0.0001
Onchocerca volvulus 0.0009 0.0023 0.0049
Loa Loa (eye worm) TK/EGFR protein kinase 0.015 0.0673 0.0673
Entamoeba histolytica protein kinase rad3, putative 0.0011 0.0032 0.0067
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0004 0.0000082046 0.0000037917
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0004 0.0000082046 0.0000037917
Leishmania major cathepsin L-like protease 0.1038 0.4741 1
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0069 0.0069
Trypanosoma cruzi hypothetical protein, conserved 0.0094 0.0415 0.0415
Echinococcus multilocularis 0.0046 0.0195 0.0195
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0031 0.0065
Brugia malayi Variant SH3 domain containing protein 0.0004 0.0000064102 0.0000064102
Echinococcus granulosus SAM domain containing protein 0.0006 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0241 0.1086 0.1086
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0006 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0032
Giardia lamblia Cathepsin L precursor 0.0241 0.1086 0.2826
Trypanosoma cruzi cysteine peptidase, putative 0.1038 0.4741 0.4741
Echinococcus granulosus cathepsin L 0.0241 0.1086 0.1086
Toxoplasma gondii cathepsin CPL 0.1038 0.4741 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0009 0.0026 0.0026
Schistosoma mansoni nAChR subunit 0.0009 0.0023 0.0023
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0241 0.1086 0.1086
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0004 0.0000082046 0.0000017976
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2185 1 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.0572 0.0572
Brugia malayi Cathepsin L-like precursor 0.1038 0.4741 0.4741
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0018 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Brugia malayi nuclear hormone receptor 0.0008 0.0018 0.0018
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.001 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0715 0.3259 0.3259
Plasmodium falciparum serine repeat antigen 3 0.0241 0.1086 0.2291
Onchocerca volvulus 0.0019 0.0069 0.0146
Echinococcus granulosus tyrosine protein kinase Srms 0.0006 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Loa Loa (eye worm) protein-tyrosine kinase 0.0004 0.000006407 0.000006407
Brugia malayi Protein kinase domain containing protein 0.0006 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Schistosoma mansoni tankyrase 0.0072 0.0316 0.0316
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0069 0.0069
Onchocerca volvulus 0.0004 0 0.0001
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0069 0.0069
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.007 0.007
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0004 0.0000082046 0.0000082046
Brugia malayi hypothetical protein 0.0006 0.0009 0.0009
Echinococcus granulosus endophilin A3 0.0004 0.000006407 0.000006407
Onchocerca volvulus Cathepsin L homolog 0.1038 0.4741 1
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0018 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0018 0.0067 0.0067
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0069 0.0069
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0069 0.0069
Onchocerca volvulus 0.0008 0.0018 0.0039
Brugia malayi hypothetical protein 0.0004 0.0002 0.0002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0241 0.1086 0.2826
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0069 0.0069
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0004 0.0000082046 0.0000037917
Echinococcus granulosus cathepsin l1 0.1038 0.4741 0.4741
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0564 0.2568 0.5416
Entamoeba histolytica hypothetical protein 0.001 0.0031 0.0065
Echinococcus granulosus tyrosine kinase 0.0006 0.0009 0.0009
Echinococcus multilocularis epidermal growth factor receptor 0.0081 0.0356 0.0356
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0241 0.1086 0.1086
Schistosoma mansoni tyrosine kinase 0.0006 0.0009 0.0009
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0004 0.0000082046 0.0000037917
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.001 0.003 0.003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0008 0.0018 0.0018
Mycobacterium leprae conserved hypothetical protein 0.0004 0.0000082046 0.5
Echinococcus granulosus tyrosine protein kinase Blk 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0006 0.0009 0.0019
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0009 0.0023 0.0023
Giardia lamblia Cathepsin B precursor 0.0842 0.3843 1
Loa Loa (eye worm) acetylcholine receptor protein 0.0009 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0323 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Echinococcus multilocularis FTZ F1 alpha 0.0008 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0013 0.0027
Brugia malayi Cathepsin L-like cysteine proteinase 0.0715 0.3259 0.3259
Brugia malayi nicalin 0.0018 0.0067 0.0067
Entamoeba histolytica cysteine protease, putative 0.0241 0.1086 0.2291
Onchocerca volvulus 0.0006 0.0009 0.0019
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Brugia malayi Variant SH3 domain containing protein 0.0004 0.000006407 0.000006407
Brugia malayi Variant SH3 domain containing protein 0.0004 0.000006407 0.000006407
Brugia malayi Papain family cysteine protease containing protein 0.0241 0.1086 0.1086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Brugia malayi protein-tyrosine kinase 0.0006 0.0009 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.0004 0.0000082046 0.0000082046
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0004 0.0000082046 0.0000017976
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0023 0.0023
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000017976
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0241 0.1086 0.2291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Plasmodium falciparum serine repeat antigen 2 0.0241 0.1086 0.2291
Echinococcus granulosus fch and double sh3 domains protein 2 0.0004 0.000006407 0.000006407
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0004 0.0000082046 0.0000037917
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1038 0.4741 1
Trypanosoma cruzi cysteine peptidase, putative 0.1038 0.4741 0.4741
Onchocerca volvulus 0.0019 0.0069 0.0146
Brugia malayi Cathepsin L-like precursor 0.0715 0.3259 0.3259
Schistosoma mansoni tyrosine kinase 0.0049 0.0207 0.0207
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.007 0.0146
Echinococcus multilocularis c src tyrosine kinase 0.0009 0.0026 0.0026
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1038 0.4741 0.4741
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0026 0.0026
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0018 0.0018
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0018 0.0067 1
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0564 0.2568 0.5416
Echinococcus multilocularis insulin receptor 0.0049 0.0207 0.0207
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Trypanosoma cruzi cysteine protease, putative 0.0564 0.2568 0.2568
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Brugia malayi Papain family cysteine protease containing protein 0.0241 0.1086 0.1086
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0055 0.0234 0.0234
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0004 0.0000082046 0.0000082046
Loa Loa (eye worm) hypothetical protein 0.0715 0.3259 0.3259
Toxoplasma gondii cathepsin CPC2 0.0241 0.1086 0.2291
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0004 0.0000082046 0.0000017976
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0023 0.0023
Leishmania major phosphatidylinositol 3-kinase, putative 0.0004 0.0000082046 0.0000037917
Onchocerca volvulus Tankyrase homolog 0.0065 0.0281 0.0593
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.1086 0.2291
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0004 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0032 0.0067
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0323 0.1465 0.1465
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0241 0.1086 0.1086
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) hypothetical protein 0.0241 0.1086 0.1086
Echinococcus granulosus tyrosine kinase 0.0006 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.1038 0.4741 0.4741
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0018 0.0018
Schistosoma mansoni nAChR subunit 0.0019 0.0069 0.0069
Brugia malayi Cathepsin L-like precursor 0.1038 0.4741 0.4741
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0004 0.0000082046 0.0000037917
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0011 0.0032 0.0032
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0004 0.0000082046 0.0000082046
Brugia malayi Cathepsin L-like precursor 0.1038 0.4741 0.4741
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.0207 0.0207
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0241 0.1086 0.2291
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0031 0.0065
Schistosoma mansoni tyrosine kinase 0.0009 0.0026 0.0026
Onchocerca volvulus 0.0004 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0241 0.1086 0.2291
Schistosoma mansoni adapter molecule crk 0.0007 0.0017 0.0017
Echinococcus multilocularis stromal interaction molecule 1 0.0006 0.0013 0.0013
Schistosoma mansoni cathepsin S (C01 family) 0.0241 0.1086 0.1086
Brugia malayi protein-tyrosine kinase 0.0004 0.000006407 0.000006407
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0069 0.0069
Entamoeba histolytica cysteine protease, putative 0.0241 0.1086 0.2291
Echinococcus granulosus tankyrase 0.0072 0.0315 0.0315
Echinococcus multilocularis epidermal growth factor receptor 0.015 0.0673 0.0673
Brugia malayi Furin-like cysteine rich region family protein 0.015 0.0673 0.0673
Entamoeba histolytica hypothetical protein 0.0241 0.1086 0.2291
Leishmania major phosphatidylinositol kinase, putative 0.0004 0.0000082046 0.0000037917
Loa Loa (eye worm) hypothetical protein 0.0239 0.1079 0.1079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1038 0.4741 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0023
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Entamoeba histolytica cysteine protease, putative 0.0564 0.2568 0.5416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.007 0.0146
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0004 0.0000082046 0.0000037917
Leishmania major phosphatidylinositol 4-kinase, putative 0.0004 0.0000082046 0.0000037917
Echinococcus granulosus poly ADP ribose polymerase 1 0.001 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0006 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0004 0.000006407 0.000006407
Echinococcus granulosus NCK adaptor protein 0.0007 0.0017 0.0017
Schistosoma mansoni lip-related protein (liprin) alpha 0.0006 0.0013 0.0013
Onchocerca volvulus Fxna peptidase homolog 0.0018 0.0067 0.0142
Onchocerca volvulus 0.0006 0.0009 0.0019
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0009 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0006 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.001 0.003 0.0063
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0004 0.000006407 0.000006407
Echinococcus multilocularis endophilin A3 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) hypothetical protein 0.0115 0.0509 0.0509
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0564 0.2568 0.5416
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0069 0.0069
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0004 0.000006407 0.000006407
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0008 0.0018 0.0018
Echinococcus multilocularis NCK adaptor protein 0.0007 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1038 0.4741 1
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0004 0.000006407 0.000006407
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0009 0.0009

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 63.0957 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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