Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0254 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0234 | 0.8326 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.3233 | 0.1027 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0234 | 0.8326 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 1 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0234 | 0.8326 | 0.8326 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0234 | 0.8326 | 1 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0234 | 0.8326 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0234 | 0.8326 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.3233 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0254 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] | ChEMBL. | No reference |
Potency (functional) | = 125.8925 um | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.