Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 100 mg kg-1 | Anticonvulsant activity in ip dosed CF1 albino mouse assessed as dose required to protect against maximal electroshock-induced seizures after 4 hrs | ChEMBL. | 20638856 |
Activity (functional) | = 100 mg kg-1 | Anticonvulsant activity in ip dosed CF1 albino mouse assessed as dose required to protect against maximal electroshock-induced seizures after 0.5 hrs | ChEMBL. | 20638856 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.