Detailed information for compound 1477910

Basic information

Technical information
  • TDR Targets ID: 1477910
  • Name: 1-[4-[2-methoxy-4-[(E)-prop-1-enyl]phenoxy]bu tyl]-3,5-dimethylpiperidine
  • MW: 331.492 | Formula: C21H33NO2
  • H donors: 0 H acceptors: 0 LogP: 5.34 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/C=C/c1ccc(c(c1)OC)OCCCCN1CC(C)CC(C1)C
  • InChi: 1S/C21H33NO2/c1-5-8-19-9-10-20(21(14-19)23-4)24-12-7-6-11-22-15-17(2)13-18(3)16-22/h5,8-10,14,17-18H,6-7,11-13,15-16H2,1-4H3/b8-5+
  • InChiKey: XJPDXOUEONEOAM-VMPITWQZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[4-(2-methoxy-4-prop-1-enylphenoxy)butyl]-3,5-dimethylpiperidine
  • 1-[4-[2-methoxy-4-[(E)-prop-1-enyl]phenoxy]butyl]-3,5-dimethyl-piperidine
  • 1-[4-(2-methoxy-4-prop-1-enyl-phenoxy)butyl]-3,5-dimethyl-piperidine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Loa Loa (eye worm) hypothetical protein 0.0033 0.0615 0.0721
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0032 0.0585 0.0684
Entamoeba histolytica cysteine protease, putative 0.0146 0.3754 0.3686
Echinococcus multilocularis tar DNA binding protein 0.0041 0.084 0.0818
Brugia malayi RNA recognition motif domain containing protein 0.0041 0.084 0.1022
Mycobacterium tuberculosis Probable hydrolase 0.0033 0.0615 0.0719
Leishmania major hypothetical protein, conserved 0.0033 0.0615 0.1586
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.2899 0.2882
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0615 0.1586
Toxoplasma gondii PHD-finger domain-containing protein 0.0012 0.0028 0.0011
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0647 0.076
Loa Loa (eye worm) hypothetical protein 0.0027 0.0464 0.0537
Toxoplasma gondii preprocathepsin c precursor, putative 0.0034 0.0647 0.1671
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0647 0.007
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0034 0.0647 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.2494 0.2149
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0146 0.3754 0.3566
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0683 0.0661
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1906 0.1487
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0647 0.007
Entamoeba histolytica cysteine protease, putative 0.0034 0.0647 0.0255
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0034 0.0647 0.1671
Entamoeba histolytica cysteine protease, putative 0.0034 0.0647 0.0255
Giardia lamblia Cathepsin L precursor 0.0034 0.0647 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Schistosoma mansoni immunophilin 0.0029 0.0502 0.0479
Entamoeba histolytica cysteine proteinase 2 0.0079 0.1906 0.1646
Loa Loa (eye worm) hypothetical protein 0.0046 0.0969 0.1153
Echinococcus granulosus cathepsin L cysteine proteinase 0.0146 0.3754 0.3739
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0012 0.0028 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0072 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0647 0.007
Echinococcus multilocularis cpg binding protein 0.0028 0.0473 0.045
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0033 0.0615 0.0079
Loa Loa (eye worm) hypothetical protein 0.0033 0.0615 0.0721
Schistosoma mansoni immunophilin 0.0033 0.0623 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Echinococcus granulosus tar DNA binding protein 0.0041 0.084 0.0818
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.003 0.0546 0.0524
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0249 0.0302
Brugia malayi Bromodomain containing protein 0.0035 0.0683 0.0831
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0072 0.0129
Loa Loa (eye worm) cathepsin B 0.0119 0.299 0.3618
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.2494 0.2149
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0033 0.0615 0.0721
Brugia malayi Cathepsin L-like precursor 0.0046 0.0969 0.1178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0032 0.0585 0.0711
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0647 0.007
Brugia malayi PHD-finger family protein 0.0035 0.0683 0.0831
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0585 0.0684
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.0159 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Leishmania major cysteine peptidase A (CPA) 0.0146 0.3754 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0065 0.0041
Giardia lamblia Cysteine protease 0.0034 0.0647 0.007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.1242 0.1221
Plasmodium falciparum serine repeat antigen 3 0.0034 0.0647 0.1671
Echinococcus multilocularis cathepsin L cysteine protease 0.0146 0.3754 0.3739
Brugia malayi beta-lactamase family protein 0.0033 0.0615 0.0748
Schistosoma mansoni hypothetical protein 0.0372 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0079 0.1906 0.5047
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0237 0.0288
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.2494 0.2295
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.2899 0.2882
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0026 0.0416 0.0393
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.003 0.0546 0.0524
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0028 0.0011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0308 0.8224 0.822
Onchocerca volvulus 0.0146 0.3754 1
Brugia malayi Cathepsin L-like precursor 0.0101 0.2494 0.3033
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0647 0.076
Echinococcus granulosus cathepsin l1 0.0146 0.3754 0.3739
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0237 0.0214
Giardia lamblia Cathepsin B precursor 0.0034 0.0647 0.007
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0647 0.0787
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0929 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0647 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0146 0.3754 0.3566
Plasmodium falciparum serine repeat antigen 8 0.0034 0.0647 0.1671
Giardia lamblia Cathepsin L-like protease 0.0034 0.0647 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0647 0.007
Echinococcus granulosus peregrin 0.0035 0.0683 0.0661
Plasmodium falciparum serine repeat antigen 2 0.0034 0.0647 0.1671
Schistosoma mansoni hypothetical protein 0.0058 0.1321 0.13
Giardia lamblia Cathepsin B precursor 0.0119 0.299 0.2707
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0647 0.076
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.7608 0.7602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0929 0.0908
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0207 0.0184
Echinococcus multilocularis cathepsin L 0.0034 0.0647 0.0625
Loa Loa (eye worm) hypothetical protein 0.0308 0.8224 1
Brugia malayi fibroinase precursor 0.0034 0.0647 0.0787
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0033 0.0615 0.0719
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.3754 0.4548
Brugia malayi cathepsin L precursor 0.0034 0.0647 0.0787
Schistosoma mansoni hypothetical protein 0.0026 0.0416 0.0393
Onchocerca volvulus 0.0146 0.3754 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0683 0.0661
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0647 0.007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.9472 1
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.003 0.0546 0.0637
Loa Loa (eye worm) hypothetical protein 0.0034 0.0647 0.076
Toxoplasma gondii cathepsin CPC2 0.0034 0.0647 0.1671
Brugia malayi isocitrate dehydrogenase 0.0019 0.0237 0.0288
Brugia malayi Cathepsin L-like precursor 0.0146 0.3754 0.4564
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0034 0.0647 0.007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0033 0.0615 0.0593
Brugia malayi cathepsin B-like cysteine proteinase 0.0308 0.8224 1
Brugia malayi jmjC domain containing protein 0.0011 0.0024 0.0029
Brugia malayi jmjC domain containing protein 0.0115 0.2899 0.3525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0647 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Plasmodium vivax unspecified product 0.0034 0.0647 0.1671
Schistosoma mansoni hypothetical protein 0.0012 0.0028 0.0004
Schistosoma mansoni hypothetical protein 0.003 0.0546 0.0524
Onchocerca volvulus 0.0058 0.1321 0.2675
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.1321 0.1606
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0647 0.007
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.4478 0.8064
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.0159 0.0363
Trypanosoma cruzi cruzipain precursor, putative 0.0046 0.0969 0.1153
Schistosoma mansoni tar DNA-binding protein 0.0041 0.084 0.0818
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0647 0.0625
Toxoplasma gondii ABC1 family protein 0.0033 0.0615 0.1586
Mycobacterium tuberculosis Conserved protein 0.0033 0.0615 0.0719
Echinococcus multilocularis cathepsin L 0.0079 0.1906 0.1887
Trypanosoma brucei PAB1-binding protein , putative 0.0016 0.0159 0.0363
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.003 0.0546 0.0524
Loa Loa (eye worm) ctsf protein 0.0146 0.3754 0.4548
Schistosoma mansoni hypothetical protein 0.0065 0.1517 0.1497
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0146 0.3754 0.3739
Loa Loa (eye worm) hypothetical protein 0.0035 0.0683 0.0804
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0683 0.0661
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0034 0.0647 0.0625
Mycobacterium ulcerans hypothetical protein 0.0033 0.0615 0.0079
Loa Loa (eye worm) hypothetical protein 0.0013 0.0069 0.0055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0079 0.1906 0.1887
Echinococcus granulosus cathepsin l cysteine peptidase 0.0146 0.3754 0.3739
Giardia lamblia Cathepsin B precursor 0.0034 0.0647 0.007
Giardia lamblia Cathepsin B precursor 0.0119 0.299 0.2707
Brugia malayi Cathepsin L-like precursor 0.0146 0.3754 0.4564
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0032 0.0585 0.0562
Onchocerca volvulus Cathepsin L homolog 0.0146 0.3754 1
Leishmania major fk506-binding protein 1-like protein 0.0032 0.0585 0.1504
Brugia malayi Cathepsin L-like precursor 0.0101 0.2494 0.3033
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0647 0.0625
Brugia malayi hypothetical protein 0.0016 0.0159 0.0194
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0028 0.0011
Brugia malayi Papain family cysteine protease containing protein 0.0146 0.3754 0.4564
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0647 0.0787
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0308 0.8224 0.822
Entamoeba histolytica cysteine proteinase, putative 0.0079 0.1906 0.1646
Schistosoma mansoni cathepsin F (C01 family) 0.0146 0.3754 0.3739
Loa Loa (eye worm) hypothetical protein 0.0096 0.2354 0.2841
Loa Loa (eye worm) hypothetical protein 0.0046 0.0969 0.1153
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0032 0.0585 0.0711
Plasmodium falciparum serine repeat antigen 7 0.0034 0.0647 0.1671
Brugia malayi Muscleblind-like protein 0.0136 0.3468 0.4216
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0026 0.0416 0.0393
Brugia malayi beta-lactamase family protein 0.0033 0.0615 0.0748
Echinococcus multilocularis cathepsin b 0.0308 0.8224 0.822
Entamoeba histolytica cysteine proteinase, putative 0.0079 0.1906 0.1646
Entamoeba histolytica cysteine protease, putative 0.0034 0.0647 0.0255
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0308 0.8224 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0046 0.0969 0.1178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Plasmodium falciparum serine repeat antigen 6 0.0034 0.0647 0.1671
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.1078 0.2827
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0034 0.0647 0.0787
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0683 0.1768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0615 0.0593
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0929 0.1104
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0034 0.0647 0.1671
Onchocerca volvulus 0.0034 0.0647 0.0647
Echinococcus multilocularis cathepsin L cysteine protease 0.0146 0.3754 0.3739
Schistosoma mansoni immunophilin 0.0033 0.0623 0.06
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0888 0.0866
Echinococcus granulosus cpg binding protein 0.0028 0.0473 0.045
Giardia lamblia Hypothetical protein 0.0034 0.0647 0.007
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0034 0.0647 0.076
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.0159 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Onchocerca volvulus 0.0101 0.2494 0.6208
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0034 0.0647 0.0625
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0034 0.0647 0.1671
Brugia malayi cathepsin L-like cysteine proteinase 0.0034 0.0647 0.0787
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0647 0.007
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0969 0.1153
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0647 0.0647
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Brugia malayi Cathepsin L-like precursor 0.0146 0.3754 0.4564
Trypanosoma cruzi cysteine proteinase, putative 0.0079 0.1906 0.2296
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0033 0.0623 0.06
Echinococcus multilocularis geminin 0.012 0.3037 0.3021
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.003 0.0546 0.0524
Echinococcus multilocularis muscleblind protein 1 0.0136 0.3468 0.3452
Mycobacterium ulcerans lipase LipD 0.0033 0.0615 0.0079
Echinococcus granulosus cathepsin l1 0.0101 0.2494 0.2476
Giardia lamblia Cysteine protease 0.0034 0.0647 0.007
Loa Loa (eye worm) hypothetical protein 0.0101 0.2494 0.3012
Echinococcus granulosus cathepsin L 0.0079 0.1906 0.1887
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0647 0.007
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0032 0.0585 0.1504
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0146 0.3754 0.3739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0647 0.007
Loa Loa (eye worm) hypothetical protein 0.0101 0.2494 0.3012
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0647 0.076
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0032 0.0585 0.0684
Schistosoma mansoni transcription factor LCR-F1 0.0026 0.0416 0.0393
Loa Loa (eye worm) hypothetical protein 0.0034 0.0647 0.076
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.1065 0.1043
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0079 0.1906 0.1887
Entamoeba histolytica cysteine protease, putative 0.0034 0.0647 0.0255
Onchocerca volvulus 0.0033 0.0615 0.0552
Mycobacterium ulcerans esterase/lipase LipP 0.0033 0.0615 0.0079
Brugia malayi Cathepsin L-like precursor 0.0146 0.3754 0.4564
Trypanosoma brucei cysteine peptidase C (CPC) 0.0119 0.299 0.7954
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0647 0.007
Brugia malayi beta-lactamase 0.0033 0.0615 0.0748
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Trypanosoma cruzi cysteine protease, putative 0.0079 0.1906 0.2296
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0034 0.0647 0.1671
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Schistosoma mansoni cathepsin F (C01 family) 0.0146 0.3754 0.3739
Loa Loa (eye worm) hypothetical protein 0.0034 0.0647 0.076
Echinococcus granulosus cathepsin b 0.0308 0.8224 0.822
Giardia lamblia Cathepsin L precursor 0.0034 0.0647 0.007
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0079 0.1906 0.1887
Brugia malayi Papain family cysteine protease containing protein 0.0079 0.1906 0.2318
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0308 0.8224 0.822
Trypanosoma cruzi cysteine proteinase, putative 0.0079 0.1906 0.2296
Echinococcus granulosus geminin 0.012 0.3037 0.3021
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0237 0.0572
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0034 0.0647 0.007
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0146 0.3754 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0033 0.0615 0.0593
Schistosoma mansoni cathepsin B (C01 family) 0.0034 0.0647 0.0625
Mycobacterium tuberculosis Probable esterase LipL 0.0033 0.0615 0.0719
Plasmodium vivax unspecified product 0.0046 0.0969 0.2534
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0237 0.026
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0033 0.0615 0.0719
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0034 0.0647 0.1671
Giardia lamblia Cathepsin L precursor 0.0034 0.0647 0.007
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0647 0.0787
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0237 0.026
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.3754 0.4548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Entamoeba histolytica hypothetical protein 0.0034 0.0647 0.0255
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0096 0.2354 0.2841
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0647 0.0255
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0032 0.0585 0.0684
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0237 0.0572
Echinococcus granulosus cathepsin L cysteine protease 0.0079 0.1906 0.1887
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0615 0.0593
Brugia malayi CXXC zinc finger family protein 0.0026 0.0432 0.0525
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0032 0.0585 0.0562
Toxoplasma gondii cathepsin CPL 0.0146 0.3754 1
Toxoplasma gondii cathepsin CPC1 0.0034 0.0647 0.1671
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.0159 0.0165
Loa Loa (eye worm) fibroinase 0.0146 0.3754 0.4548
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.2494 0.2476
Schistosoma mansoni cpg binding protein 0.0026 0.0432 0.0409
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.172 0.2069
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0647 0.0787
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.9472 1
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0615 0.0035
Brugia malayi latrophilin 2 splice variant baaae 0.0065 0.1517 0.1845
Brugia malayi hypothetical protein 0.0286 0.7608 0.925
Schistosoma mansoni hypothetical protein 0.003 0.0546 0.0524
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0237 0.0572
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Giardia lamblia Cathepsin B precursor 0.0034 0.0647 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0615 0.0721
Onchocerca volvulus 0.0146 0.3754 1
Mycobacterium tuberculosis Probable lipase LipE 0.0033 0.0615 0.0719
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0079 0.1906 0.1487
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0119 0.299 0.2974
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0615 0.0035
Echinococcus granulosus muscleblind protein 0.0136 0.3468 0.3452
Plasmodium falciparum serine repeat antigen 1 0.0034 0.0647 0.1671
Schistosoma mansoni cpg binding protein 0.0028 0.0473 0.045
Onchocerca volvulus Cathepsin F homolog 0.0146 0.3754 1
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0615 0.1586
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0034 0.0647 0.007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0647 0.076
Brugia malayi cathepsin Z-like cysteine proteinase 0.0034 0.0647 0.0787
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0146 0.3754 0.4548
Mycobacterium tuberculosis Conserved protein 0.0033 0.0615 0.0719
Brugia malayi Cathepsin L-like precursor 0.0146 0.3754 0.4564
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0096 0.2354 0.2862
Schistosoma mansoni hypothetical protein 0.012 0.3037 0.3021
Trypanosoma cruzi cruzipain precursor, putative 0.0146 0.3754 0.4548
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0647 0.0625
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Brugia malayi Cathepsin L-like cysteine proteinase 0.0101 0.2494 0.3033
Loa Loa (eye worm) hypothetical protein 0.0065 0.1517 0.1821
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.9472 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0237 0.026
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0146 0.3754 0.4548
Brugia malayi AF-10 protein 0.0012 0.0028 0.0034
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.003 0.0546 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0615 0.0721
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0119 0.299 0.2707
Entamoeba histolytica cysteine proteinase, putative 0.0079 0.1906 0.1646
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0683 0.1768
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0046 0.0969 0.1153
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0237 0.0572
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0119 0.299 0.3618
Loa Loa (eye worm) hypothetical protein 0.0046 0.0969 0.1153
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.4478 1
Schistosoma mansoni tar DNA-binding protein 0.0041 0.084 0.0818
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0683 0.0804
Mycobacterium ulcerans beta-lactamase 0.0033 0.0615 0.0079
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0237 0.0214
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0647 0.0625
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0647 0.1671
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.3754 0.4548
Loa Loa (eye worm) hypothetical protein 0.0033 0.0615 0.0721
Onchocerca volvulus 0.0033 0.0615 0.0552
Brugia malayi cathepsin L-like precursor 0.0101 0.2494 0.3033
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0034 0.0647 0.007
Plasmodium vivax ataxin-2 like protein, putative 0.0016 0.0159 0.0363
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Plasmodium vivax vivapain-1 0.0079 0.1906 0.5047
Schistosoma mansoni hypothetical protein 0.003 0.0546 0.0524
Mycobacterium tuberculosis Probable lipase LipD 0.0033 0.0615 0.0719
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0034 0.0647 0.1671
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0209 0.5497 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0647 0.1671
Schistosoma mansoni hypothetical protein 0.0035 0.0683 0.0661
Giardia lamblia Encystation-specific protease 0.0034 0.0647 0.007
Brugia malayi jmjC domain containing protein 0.0011 0.0024 0.0029
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0237 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0165
Brugia malayi Papain family cysteine protease containing protein 0.0079 0.1906 0.2318
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0034 0.0647 0.1671
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0033 0.0623 0.0228
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0929 0.0908
Entamoeba histolytica cysteine protease, putative 0.0034 0.0647 0.0255
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0237 0.0214
Echinococcus granulosus cathepsin b 0.0308 0.8224 0.822
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0032 0.0585 0.1504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0146 0.3754 1
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Onchocerca volvulus Alhambra homolog 0.0035 0.0683 0.0756
Plasmodium vivax vivapain-3 0.0079 0.1906 0.5047
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0647 0.007
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0119 0.299 0.7954
Entamoeba histolytica cysteine proteinase, putative 0.0079 0.1906 0.1646
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0033 0.0623 0.0228
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0079 0.1906 0.2296
Schistosoma mansoni tar DNA-binding protein 0.0041 0.084 0.0818
Echinococcus granulosus cathepsin L 0.0034 0.0647 0.0625
Entamoeba histolytica cysteine protease, putative 0.0034 0.0647 0.0255
Giardia lamblia Cathepsin L precursor 0.0034 0.0647 0.007
Loa Loa (eye worm) hypothetical protein 0.0136 0.3468 0.42
Schistosoma mansoni cathepsin s 0.0046 0.0969 0.0947
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Loa Loa (eye worm) hypothetical protein 0.006 0.1379 0.1652
Schistosoma mansoni cathepsin C 0.0034 0.0647 0.0625
Echinococcus multilocularis peregrin 0.0035 0.0683 0.0661
Brugia malayi cathepsin F-like cysteine proteinase 0.0034 0.0647 0.0787
Echinococcus granulosus lysine specific demethylase 6a 0.0011 0.0024 0.0000071748
Brugia malayi PHD-finger family protein 0.0013 0.0069 0.0084
Echinococcus multilocularis cysteine protease 0.0146 0.3754 0.3739
Echinococcus multilocularis dnaJ subfamily B 0.0372 1 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0033 0.0615 0.0748
Giardia lamblia PHD finger protein 15 0.0035 0.0683 0.0111
Brugia malayi jmjC domain containing protein 0.0044 0.0929 0.113
Echinococcus multilocularis lysine specific demethylase 6a 0.0011 0.0024 0.0000071748
Echinococcus multilocularis fk506 binding protein 0.0032 0.0585 0.0562
Mycobacterium tuberculosis Conserved protein 0.0033 0.0615 0.0719
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0034 0.0647 0.1671
Plasmodium falciparum serine repeat antigen 4 0.0034 0.0647 0.1671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0034 0.0647 0.1671
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Schistosoma mansoni tar DNA-binding protein 0.0041 0.084 0.0818
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0237 0.0572
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Plasmodium falciparum serine repeat antigen 5 0.0034 0.0647 0.1671
Loa Loa (eye worm) hypothetical protein 0.0146 0.3754 0.4548
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0585 0.0684
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Onchocerca volvulus 0.0146 0.3754 1
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.7608 0.7602
Loa Loa (eye worm) hypothetical protein 0.0101 0.2494 0.3012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0615 0.0721
Plasmodium vivax vivapain-2 0.0146 0.3754 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0034 0.0647 0.007
Loa Loa (eye worm) RNA binding protein 0.0041 0.084 0.0995
Brugia malayi Cathepsin L-like precursor 0.0146 0.3754 0.4564
Schistosoma mansoni cathepsin S (C01 family) 0.0034 0.0647 0.0625
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0683 0.1768
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0585 0.1504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0079 0.1906 0.5047
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Onchocerca volvulus 0.0146 0.3754 1
Entamoeba histolytica cysteine proteinase, putative 0.0146 0.3754 0.3686
Plasmodium vivax unspecified product 0.0079 0.1906 0.5047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Giardia lamblia Cathepsin L precursor 0.0034 0.0647 0.007
Schistosoma mansoni survival motor neuron protein 0.0058 0.1321 0.13
Schistosoma mansoni hypothetical protein 0.012 0.3037 0.3021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0647 0.0625
Leishmania major hypothetical protein, conserved 0.0016 0.0159 0.0363
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0615 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0647 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0065 0.0041
Loa Loa (eye worm) cysteine protease 0.0146 0.3754 0.4548
Trichomonas vaginalis esterase, putative 0.0033 0.0615 0.0035
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0033 0.0623 0.06
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0615 0.0035
Schistosoma mansoni jumonji domain containing protein 0.0092 0.2243 0.2225
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0079 0.1906 0.5047
Plasmodium falciparum serine repeat antigen 9 0.0034 0.0647 0.1671
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Brugia malayi cathepsin F-like cysteine proteinase 0.0046 0.0969 0.1178
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0033 0.0615 0.0719
Brugia malayi hypothetical protein 0.0026 0.0416 0.0506
Loa Loa (eye worm) hypothetical protein 0.0136 0.3468 0.42
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0034 0.0647 0.0625
Schistosoma mansoni hypothetical protein 0.003 0.0546 0.0524
Loa Loa (eye worm) CXXC zinc finger family protein 0.0026 0.0432 0.0498
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0034 0.0647 0.1671
Giardia lamblia Hypothetical protein 0.0034 0.0647 0.007
Leishmania major cathepsin L-like protease 0.0146 0.3754 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0034 0.0647 0.0255
Echinococcus granulosus jumonji domain containing protein 0.0049 0.1065 0.1043
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0032 0.0585 0.1504
Giardia lamblia Cathepsin B precursor 0.0034 0.0647 0.007
Leishmania major peptidylprolyl isomerase-like protein 0.0032 0.0585 0.1504
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.9472 1
Echinococcus granulosus cysteine protease 0.0079 0.1906 0.1887
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0041 0.084 0.0995
Brugia malayi TAR-binding protein 0.0041 0.084 0.1022
Loa Loa (eye worm) beta-lactamase 0.0033 0.0615 0.0721
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0237 0.0572
Entamoeba histolytica cysteine proteinase, putative 0.0146 0.3754 0.3686
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0237 0.0572
Onchocerca volvulus Cathepsin L homolog 0.0146 0.3754 1
Loa Loa (eye worm) TAR-binding protein 0.0041 0.084 0.0995
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0647 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.3754 1
Echinococcus granulosus GPCR family 2 0.003 0.0546 0.0524
Loa Loa (eye worm) FKBP5 protein 0.0032 0.0585 0.0684
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Giardia lamblia Cysteine protease 0.0034 0.0647 0.007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0615 0.0721
Giardia lamblia Cathepsin L-like protease 0.0034 0.0647 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0034 0.0647 0.007
Brugia malayi jmjC domain containing protein 0.0011 0.0024 0.0029
Plasmodium falciparum phd finger protein, putative 0.0035 0.0683 0.1768
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.3754 0.4548
Onchocerca volvulus 0.0146 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0647 0.076
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Onchocerca volvulus 0.0146 0.3754 1
Schistosoma mansoni cpg binding protein 0.0028 0.0473 0.045
Toxoplasma gondii cathepsin B 0.0119 0.299 0.7954
Echinococcus multilocularis cathepsin b 0.0308 0.8224 0.822
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0308 0.8224 0.822
Giardia lamblia Cathepsin B precursor 0.0034 0.0647 0.007
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0034 0.0647 0.1671
Entamoeba histolytica cysteine proteinase 1, putative 0.0079 0.1906 0.1646
Giardia lamblia Cathepsin L precursor 0.0034 0.0647 0.007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0146 0.3754 0.3566
Toxoplasma gondii LsmAD domain-containing protein 0.0016 0.0159 0.0363
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0034 0.0647 0.1671
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0034 0.0647 0.0625
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0029 0.0502 0.0479
Giardia lamblia Cathepsin B precursor 0.0119 0.299 0.2707
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Schistosoma mansoni tar DNA-binding protein 0.0041 0.084 0.0818
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0146 0.3754 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0237 0.0214
Brugia malayi Latrophilin receptor protein 2 0.003 0.0546 0.0664
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0237 0.0214
Brugia malayi Calcitonin receptor-like protein seb-1 0.0096 0.2354 0.2862
Plasmodium vivax vivapain-2 0.0146 0.3754 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.9472 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Loa Loa (eye worm) hypothetical protein 0.0033 0.0615 0.0721
Loa Loa (eye worm) hypothetical protein 0.003 0.0546 0.0637
Trypanosoma cruzi cysteine peptidase, putative 0.0079 0.1906 0.2296
Giardia lamblia Cysteine protease 0.0034 0.0647 0.007
Echinococcus multilocularis cysteine protease 0.0146 0.3754 0.3739
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0029 0.0502 0.0479
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Brugia malayi jmjC domain containing protein 0.0011 0.0024 0.0029
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0615 0.0035
Entamoeba histolytica cysteine protease, putative 0.0079 0.1906 0.1646
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.4478 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0146 0.3754 0.3566
Echinococcus multilocularis muscleblind protein 0.0136 0.3468 0.3452
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0647 0.076
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0034 0.0647 0.1671
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0101 0.2494 0.3012
Onchocerca volvulus 0.0033 0.0615 0.0552
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0237 0.0214
Brugia malayi RNA binding protein 0.0041 0.084 0.1022
Loa Loa (eye worm) hypothetical protein 0.0286 0.7608 0.9248
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0013 0.0062 0.0038
Echinococcus multilocularis GPCR, family 2 0.003 0.0546 0.0524

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.