Detailed information for compound 1482323

Basic information

Technical information
  • TDR Targets ID: 1482323
  • Name: 6-pyrrolidin-1-ylsulfonyl-1,2,3,4-tetrahydroq uinoline
  • MW: 266.359 | Formula: C13H18N2O2S
  • H donors: 1 H acceptors: 2 LogP: 1.93 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=S(=O)(c1ccc2c(c1)CCCN2)N1CCCC1
  • InChi: 1S/C13H18N2O2S/c16-18(17,15-8-1-2-9-15)12-5-6-13-11(10-12)4-3-7-14-13/h5-6,10,14H,1-4,7-9H2
  • InChiKey: CVGAVEBLFIEIQO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-1-pyrrolidinylsulfonyl-1,2,3,4-tetrahydroquinoline
  • ZINC03888986

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0073 0.0432 0.0432
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0031 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0029 0.0033
Echinococcus multilocularis serotonin receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Leishmania major glucose transporter, lmgt1 0.0032 0.013 0.0322
Schistosoma mansoni metabotropic glutamate receptor 0.0059 0.0331 0.0331
Loa Loa (eye worm) cysteine protease 0.0561 0.4038 0.4684
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.013 0.0853 0.2113
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0122 0.0436
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0065 0.014
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0853 0.2044
Entamoeba histolytica cysteine protease, putative 0.013 0.0853 0.1989
Schistosoma mansoni glucose transport protein 0.0104 0.066 0.066
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0035 0.0175
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0255 0.0255
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0695 0.1721
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0695 0.0695
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0063 0.0152
Giardia lamblia Fructose-bisphosphate aldolase 0.0579 0.4173 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.03 0.03
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0153 0.0153
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0031 0.0036
Brugia malayi cathepsin Z-like cysteine proteinase 0.013 0.0853 0.099
Brugia malayi Cathepsin L-like precursor 0.0386 0.2747 0.3186
Onchocerca volvulus Cathepsin L homolog 0.013 0.0853 0.2113
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0127 0.0315
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.013 0.0853 0.0853
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.002 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.004
Brugia malayi ORL1-like opioid receptor 0.0049 0.0255 0.0296
Echinococcus multilocularis cathepsin b 0.1181 0.862 0.862
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.0044
Brugia malayi metabotropic glutamate receptor type 2 0.0059 0.0331 0.0384
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.004 0.0047
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0238 0.0276
Echinococcus multilocularis cathepsin L 0.0305 0.2144 0.2144
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.004 0.004
Schistosoma mansoni lozenge 0.0056 0.0303 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Echinococcus granulosus tar DNA binding protein 0.0062 0.0352 0.0352
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0283 0.1983 1
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0035 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.013 0.0853 0.2044
Loa Loa (eye worm) steroid hormone receptor 0.002 0.004 0.0047
Onchocerca volvulus 0.0386 0.2747 0.6802
Brugia malayi hypothetical protein 0.0443 0.3164 0.367
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.004 0.004
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0038 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0239 0.0593
Schistosoma mansoni zinc finger protein 0.0021 0.0049 0.0049
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0255 0.0255
Schistosoma mansoni thyroid hormone receptor 0.002 0.004 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0031 0.0123 0.0142
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0561 0.4038 1
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0255 0.0255
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0239 0.0509
Brugia malayi cathepsin L precursor 0.013 0.0853 0.099
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Onchocerca volvulus 0.0047 0.0239 0.0593
Loa Loa (eye worm) ctsf protein 0.0561 0.4038 0.4684
Giardia lamblia Cysteine protease 0.013 0.0853 0.2044
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Onchocerca volvulus Cathepsin L homolog 0.0561 0.4038 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.013 0.0853 0.099
Echinococcus granulosus g protein coupled receptor 0.0049 0.0255 0.0255
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0035 0.0152 0.0176
Onchocerca volvulus 0.0049 0.0255 0.0631
Onchocerca volvulus 0.0049 0.0255 0.0631
Echinococcus multilocularis cathepsin L cysteine protease 0.0561 0.4038 0.4038
Entamoeba histolytica hypothetical protein 0.013 0.0853 0.1989
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0239 0.1207
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.004 0.0047
Echinococcus granulosus GPCR family 3 C terminal 0.002 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0386 0.2747 0.3186
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0502
Echinococcus granulosus g protein coupled receptor 0.0049 0.0255 0.0255
Trypanosoma brucei cysteine peptidase C (CPC) 0.0455 0.3255 0.8062
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0255 0.0255
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Leishmania major hypothetical protein, conserved 0.0015 0.0005 0.0013
Onchocerca volvulus 0.0561 0.4038 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.013 0.0853 0.2113
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0432 0.1036
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.002 0.0038 0.0095
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0065 0.0161
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0255 0.0255
Brugia malayi Cathepsin L-like precursor 0.0561 0.4038 0.4684
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0063 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.013 0.0853 0.2044
Trypanosoma cruzi major cysteine proteinase, putative 0.013 0.0853 0.099
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0046 0.0053
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0035 0.0035
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0175 0.1183 0.1373
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0029 0.0144
Loa Loa (eye worm) papain family cysteine protease containing protein 0.013 0.0853 0.099
Echinococcus granulosus cathepsin L cysteine proteinase 0.0561 0.4038 0.4038
Onchocerca volvulus 0.0561 0.4038 1
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0122 0.0293
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0031 0.0031
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0063 0.0063
Brugia malayi Bromodomain containing protein 0.0077 0.0458 0.0532
Loa Loa (eye worm) hypothetical protein 0.0041 0.0193 0.0224
Echinococcus multilocularis cysteine protease 0.0561 0.4038 0.4038
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.004 0.004
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0607 0.0607
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.03 0.0349
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus granulosus allatostatin A receptor 0.0049 0.0255 0.0255
Schistosoma mansoni protein kinase 0.0032 0.0127 0.0127
Giardia lamblia Dipeptidyl-peptidase I precursor 0.013 0.0853 0.2044
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0305 0.2144 0.2144
Brugia malayi PXA domain containing protein 0.0019 0.0031 0.0036
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0127 0.0127
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.013 0.0853 0.2113
Brugia malayi cathepsin F-like cysteine proteinase 0.013 0.0853 0.099
Loa Loa (eye worm) hypothetical protein 0.0047 0.0239 0.0278
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0352 0.0352
Plasmodium vivax hexose transporter 0.0104 0.066 0.1633
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.03 0.03
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0334 0.0334
Echinococcus granulosus metabotropic glutamate receptor 5 0.015 0.1 0.1
Onchocerca volvulus 0.0049 0.0255 0.0631
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0695 0.0806
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0063 0.0157
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0695 0.1721
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.004 0.004
Giardia lamblia Cathepsin L precursor 0.013 0.0853 0.2044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.004
Entamoeba histolytica cysteine proteinase, putative 0.0561 0.4038 0.9673
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0031 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0046 0.0046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0035 0.0175
Brugia malayi Dopamine receptor 0.0049 0.0255 0.0296
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.013 0.0853 0.0853
Schistosoma mansoni metabotropic glutamate receptor 0.0102 0.0646 0.0646
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0647 0.0647
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0255 0.0255
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1181 0.862 0.862
Brugia malayi G protein-coupled receptor 0.0049 0.0255 0.0296
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Echinococcus multilocularis FTZ F1 alpha 0.002 0.004 0.004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.013 0.0853 0.0853
Echinococcus granulosus dna polymerase eta 0.0019 0.0035 0.0035
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.013 0.0853 0.099
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.013 0.0853 0.2113
Loa Loa (eye worm) hypothetical protein 0.0122 0.0797 0.0925
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0345 0.0345
Echinococcus granulosus geminin 0.0205 0.1405 0.1405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.004 0.0047
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0123 0.0304
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0031 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Echinococcus multilocularis neuropeptide s receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0561 0.4038 0.4684
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Plasmodium falciparum serine repeat antigen 1 0.013 0.0853 0.2113
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0255 0.0296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Echinococcus multilocularis dna polymerase eta 0.0019 0.0035 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0432 0.1036
Echinococcus granulosus tumor protein p63 0.0408 0.2909 0.2909
Entamoeba histolytica cysteine proteinase, putative 0.0305 0.2144 0.5104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Entamoeba histolytica hypothetical protein 0.0019 0.0031 0.0007
Entamoeba histolytica protein kinase, putative 0.0032 0.0127 0.0238
Brugia malayi Bromodomain containing protein 0.0038 0.0175 0.0203
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0255 0.0255
Brugia malayi Metabotropic glutamate receptor precursor. 0.0122 0.0792 0.0919
Brugia malayi 6-phosphofructokinase 0.0109 0.0695 0.0806
Schistosoma mansoni protein kinase 0.0032 0.0127 0.0127
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0255 0.0255
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0065 0.0161
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0239 0.1207
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0073 0.0432 0.0432
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0695 0.0806
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.013 0.0853 0.2113
Schistosoma mansoni amine GPCR 0.0049 0.0255 0.0255
Schistosoma mansoni cathepsin S (C01 family) 0.013 0.0853 0.0853
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0109 0.0194
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0239 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0175 0.1183 0.1373
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0127 0.0147
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.004 0.004
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.013 0.0853 0.2044
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.004 0.0047
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0255 0.0255
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0352 0.0352
Entamoeba histolytica hypothetical protein 0.0019 0.0031 0.0007
Plasmodium vivax serine-repeat antigen (SERA), putative 0.013 0.0853 0.2113
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0073 0.0432 0.0432
Plasmodium falciparum serine repeat antigen 4 0.013 0.0853 0.2113
Schistosoma mansoni cpg binding protein 0.0032 0.013 0.013
Schistosoma mansoni microtubule-associated protein tau 0.1367 1 1
Onchocerca volvulus 0.0049 0.0255 0.0631
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.004 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.004 0.004
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0255 0.0631
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0368 0.0427
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis GPCR, family 2 0.0047 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0035 0.0152 0.0176
Entamoeba histolytica hypothetical protein 0.0019 0.0031 0.0007
Schistosoma mansoni hypothetical protein 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.006 0.0334 0.0387
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0255 0.0296
Plasmodium vivax unspecified product 0.0175 0.1183 0.293
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0695 0.1666
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0142
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0123 0.0142
Schistosoma mansoni protein kinase 0.0032 0.0127 0.0127
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0607 0.0704
Schistosoma mansoni cpg binding protein 0.0032 0.013 0.013
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0029 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0073 0.0432 0.0975
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0092
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0695 0.0806
Toxoplasma gondii preprocathepsin c precursor, putative 0.013 0.0853 0.2113
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0561 0.4038 0.4038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0031
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Leishmania major DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.013 0.0853 0.0853
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0255 0.0255
Giardia lamblia Cathepsin L precursor 0.013 0.0853 0.2044
Giardia lamblia Cathepsin B precursor 0.0455 0.3255 0.78
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0432 0.0502
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0239 0.0593
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0063 0.032
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0063 0.0074
Brugia malayi Papain family cysteine protease containing protein 0.0305 0.2144 0.2487
Schistosoma mansoni glucose transport protein 0.0104 0.066 0.066
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0071 0.0071
Brugia malayi Steroid receptor seven-up type 2 0.002 0.004 0.0047
Plasmodium vivax vivapain-2 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0638 0.0741
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0137 0.0693
Loa Loa (eye worm) RNA binding protein 0.0062 0.0352 0.0408
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0142
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0255 0.0296
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.002 0.0038 0.0038
Entamoeba histolytica cysteine protease, putative 0.0561 0.4038 0.9673
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.013 0.0853 0.0853
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0984 0.1141
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0031
Plasmodium falciparum protein kinase 7 0.0293 0.206 0.5103
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0046 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0029 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0035 0.0175
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0171 0.0171
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1181 0.862 0.862
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0031 0.0031
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0255 0.0255
Brugia malayi cahepsin L-like non-peptiedase homolog 0.013 0.0853 0.099
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.013 0.0853 0.2113
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0031 0.0031
Echinococcus granulosus zinc finger protein 0.0021 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0984 0.1141
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Echinococcus granulosus cpg binding protein 0.0032 0.013 0.013
Brugia malayi larval opioid receptor 0.0049 0.0255 0.0296
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0127 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.004 0.0047
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0045 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.013 0.0853 0.2044
Brugia malayi hypothetical protein 0.0019 0.0031 0.0036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0238 0.0238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0305 0.2144 0.531
Onchocerca volvulus 0.0443 0.3164 0.7836
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0031 0.0031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0312 0.0772
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0638 0.0741
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0506 0.0587
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Schistosoma mansoni hypothetical protein 0.0031 0.0123 0.0123
Giardia lamblia Cathepsin B precursor 0.0455 0.3255 0.78
Echinococcus multilocularis geminin 0.0205 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0053 0.0287 0.0333
Loa Loa (eye worm) hypothetical protein 0.0071 0.0415 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.013 0.0853 0.2044
Entamoeba histolytica papain family cysteine protease domain containing protein 0.013 0.0853 0.1989
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0046 0.0046
Schistosoma mansoni biogenic amine receptor 0.0049 0.0255 0.0255
Brugia malayi RNA binding protein 0.0062 0.0352 0.0408
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.013 0.0322
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.015 0.1 0.116
Giardia lamblia Cathepsin B precursor 0.013 0.0853 0.2044
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0152 0.0764
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0255 0.0255
Schistosoma mansoni glucose transport protein 0.0104 0.066 0.066
Echinococcus multilocularis neuropeptide receptor A26 0.0049 0.0255 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Entamoeba histolytica hypothetical protein 0.0023 0.0065 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Schistosoma mansoni hypothetical protein 0.0205 0.1405 0.1405
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0075
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0199 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.004 0.0047
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0255 0.0296
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0175 0.1183 0.1373
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0579 0.4173 1
Onchocerca volvulus 0.0561 0.4038 1
Echinococcus granulosus cathepsin l1 0.0561 0.4038 0.4038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0255 0.0296
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0065 0.0088
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0261
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Brugia malayi jmjC domain containing protein 0.0102 0.0647 0.075
Loa Loa (eye worm) hypothetical protein 0.0097 0.0607 0.0704
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.013 0.0853 0.2044
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Brugia malayi putative neuropeptide receptor 0.0049 0.0255 0.0296
Schistosoma mansoni bromodomain containing protein 0.0065 0.0372 0.0372
Trypanosoma cruzi ISWI complex protein 0.0015 0.0005 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.004 0.004
Brugia malayi 6-phosphofructokinase 0.0109 0.0695 0.0806
Brugia malayi Papain family cysteine protease containing protein 0.0305 0.2144 0.2487
Loa Loa (eye worm) hypothetical protein 0.013 0.0853 0.099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.004 0.0047
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.013 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0432 0.1036
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0065 0.0161
Toxoplasma gondii exonuclease III APE 0.0018 0.0029 0.0071
Schistosoma mansoni cathepsin F (C01 family) 0.0386 0.2747 0.2747
Echinococcus granulosus sex peptide receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.016 0.0397
Brugia malayi metabotropic GABA-B receptor subtype 2 0.002 0.0038 0.0044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0238 0.0238
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0188
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0127 0.0315
Schistosoma mansoni neuropeptide receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0023 0.0023
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0123 0.0123
Echinococcus granulosus neuropeptide s receptor 0.0049 0.0255 0.0255
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0046 0.0046
Brugia malayi G-protein coupled receptor 0.0049 0.0255 0.0296
Plasmodium vivax vivapain-1 0.0305 0.2144 0.531
Giardia lamblia Encystation-specific protease 0.013 0.0853 0.2044
Schistosoma mansoni nuclear hormone receptor 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0127 0.0315
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.004 0.004
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0109 0.0261
Onchocerca volvulus 0.0049 0.0255 0.0631
Onchocerca volvulus Poor gastrulation protein homolog 0.002 0.0038 0.0095
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.004
Brugia malayi jmjC domain containing protein 0.0041 0.0197 0.0229
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.013 0.0853 0.099
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Onchocerca volvulus Alhambra homolog 0.0031 0.0123 0.0304
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.004 0.004
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Echinococcus granulosus fmrfamide receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0036
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.013 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0127 0.0315
Loa Loa (eye worm) hypothetical protein 0.0148 0.0984 0.1141
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0239 0.1207
Leishmania major protein kinase, putative 0.0032 0.0127 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.013 0.0853 0.2044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.03 0.03
Plasmodium falciparum serine repeat antigen 9 0.013 0.0853 0.2113
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0031 0.0036
Echinococcus granulosus dna polymerase kappa 0.0019 0.0035 0.0035
Giardia lamblia Cathepsin B precursor 0.013 0.0853 0.2044
Plasmodium falciparum serine repeat antigen 2 0.013 0.0853 0.2113
Giardia lamblia Cathepsin L precursor 0.013 0.0853 0.2044
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0031 0.0031
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0038 0.0189
Giardia lamblia Cathepsin B precursor 0.013 0.0853 0.2044
Trypanosoma brucei glucose transporter 1E 0.0032 0.013 0.0322
Schistosoma mansoni ap endonuclease 0.0018 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0386 0.2747 0.3186
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Entamoeba histolytica cysteine protease, putative 0.013 0.0853 0.1989
Brugia malayi Cathepsin L-like precursor 0.0561 0.4038 0.4684
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0127 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0032 0.013 0.0312
Entamoeba histolytica cysteine protease, putative 0.013 0.0853 0.1989
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0255 0.0296
Brugia malayi Cathepsin L-like precursor 0.0561 0.4038 0.4684
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Plasmodium falciparum mitogen-activated protein kinase 2 0.0168 0.1132 0.2804
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis somatostatin receptor 0.0049 0.0255 0.0255
Giardia lamblia Cysteine protease 0.013 0.0853 0.2044
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.004 0.004
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.004 0.004
Schistosoma mansoni neuropeptide receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0065 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0255 0.0255
Giardia lamblia Hypothetical protein 0.013 0.0853 0.2044
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0123 0.0304
Schistosoma mansoni histamine h1 receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.013 0.0853 0.099
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0158 0.0158
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.013 0.0853 0.2113
Onchocerca volvulus 0.006 0.0334 0.0826
Plasmodium vivax serine-repeat antigen (SERA) 0.013 0.0853 0.2113
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Schistosoma mansoni hypothetical protein 0.0049 0.0255 0.0255
Entamoeba histolytica hypothetical protein 0.0035 0.0153 0.0301
Echinococcus multilocularis peregrin 0.0034 0.014 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.013 0.0853 0.2044
Onchocerca volvulus Cathepsin F homolog 0.0561 0.4038 1
Onchocerca volvulus Huntingtin homolog 0.0122 0.0797 0.1974
Entamoeba histolytica hypothetical protein 0.0035 0.0153 0.0301
Onchocerca volvulus 0.0029 0.0104 0.0258
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0255 0.0255
Schistosoma mansoni coup transcription factor 0.002 0.004 0.004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0238 0.0276
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0199 0.0199
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0138 0.0915 0.0915
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Echinococcus granulosus somatostatin receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.013 0.0853 0.2044
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0255 0.0296
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.013 0.0322
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0175 0.1183 0.1373
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0342 0.0342
Echinococcus multilocularis protein patched 0.0041 0.0199 0.0199
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0197 0.0197
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0035 0.0083
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Schistosoma mansoni hypothetical protein 0.0047 0.0238 0.0238
Loa Loa (eye worm) glutamate receptor 0.0048 0.0246 0.0286
Trypanosoma brucei unspecified product 0.0019 0.0035 0.0086
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0255 0.0296
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0695 0.1608
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0255 0.0296
Brugia malayi Papain family cysteine protease containing protein 0.013 0.0853 0.099
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0022 0.0026
Echinococcus granulosus neuropeptide receptor 0.0049 0.0255 0.0255
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0255 0.0255
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0255 0.0255
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Plasmodium vivax serine-repeat antigen (SERA) 0.013 0.0853 0.2113
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0035 0.0035
Schistosoma mansoni biogenic amine receptor 0.0049 0.0255 0.0255
Brugia malayi cathepsin F-like cysteine proteinase 0.0175 0.1183 0.1373
Schistosoma mansoni opsin-like receptor 0.0049 0.0255 0.0255
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0238 0.0276
Echinococcus granulosus General substrate transporter 0.0089 0.0552 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0352 0.0352
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0063 0.0063
Brugia malayi Papain family cysteine protease containing protein 0.013 0.0853 0.099
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.013 0.0312
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0035 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.013 0.0853 0.2044
Toxoplasma gondii protein kinase, putative 0.0293 0.206 0.5103
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0255 0.0255
Entamoeba histolytica hypothetical protein 0.0035 0.0153 0.0301
Trypanosoma cruzi cysteine peptidase, putative 0.0561 0.4038 0.4684
Loa Loa (eye worm) hypothetical protein 0.0386 0.2747 0.3186
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0239 0.1207
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0127 0.0315
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0255 0.0296
Onchocerca volvulus 0.0049 0.0255 0.0631
Schistosoma mansoni amine GPCR 0.0049 0.0255 0.0255
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.004 0.004
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0152 0.0375
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.004
Plasmodium falciparum proline--tRNA ligase 0.0036 0.016 0.0397
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0065 0.0161
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0239 0.0509
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0023 0.0023
Onchocerca volvulus 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Entamoeba histolytica cysteine proteinase 2 0.0305 0.2144 0.5104
Loa Loa (eye worm) runx1 0.0056 0.0303 0.0351
Onchocerca volvulus 0.0561 0.4038 1
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0035 0.0152 0.0176
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0018 0.0018
Trypanosoma cruzi major cysteine proteinase, putative 0.013 0.0853 0.099
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0127 0.0127
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.004 0.0099
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0031 0.0031
Brugia malayi PHD-finger family protein 0.0031 0.0123 0.0142
Brugia malayi Receptor family ligand binding region containing protein 0.0031 0.0123 0.0142
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.066 0.066
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Plasmodium falciparum serine repeat antigen 6 0.013 0.0853 0.2113
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0035 0.0015
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.013 0.0853 0.2044
Echinococcus multilocularis microtubule associated protein 2 0.1367 1 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0031 0.0031
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0168 0.1132 0.2804
Brugia malayi Serotonin receptor 0.0049 0.0255 0.0296
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0455 0.3255 0.3255
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Schistosoma mansoni opsin-like receptor 0.0049 0.0255 0.0255
Brugia malayi TAR-binding protein 0.0062 0.0352 0.0408
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Brugia malayi Dopamine receptor protein 1 0.0049 0.0255 0.0296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Echinococcus multilocularis zinc finger protein 0.0021 0.0049 0.0049
Entamoeba histolytica cysteine proteinase, putative 0.0386 0.2747 0.6558
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.016 0.0186
Entamoeba histolytica cysteine proteinase 1, putative 0.0305 0.2144 0.5104
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0796 0.578 0.578
Schistosoma mansoni ap endonuclease 0.0018 0.0029 0.0029
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0255 0.0255
Giardia lamblia DINP protein human, muc B family 0.0019 0.0035 0.0083
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0188
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0031 0.0031
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.004 0.004
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0695 0.3379
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.013 0.0853 0.2044
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0261
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0561 0.4038 0.4684
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.004 0.004
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0197 0.0197
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.004 0.0099
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.03 0.03
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0345 0.0345
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0065 0.0327
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0035 0.0035
Brugia malayi Cathepsin L-like precursor 0.0561 0.4038 0.4684
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.004 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.013 0.0853 0.2044
Trypanosoma cruzi cysteine peptidase, putative 0.0561 0.4038 0.4684
Brugia malayi hypothetical protein 0.0019 0.0031 0.0036
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0255 0.0255
Plasmodium vivax unspecified product 0.013 0.0853 0.2113
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0029 0.4399
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0123 0.0304
Echinococcus multilocularis sex peptide receptor 0.0049 0.0255 0.0255
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.004 0.004
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0031 0.0123 0.0142
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0255 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0075
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0579 0.4173 1
Echinococcus granulosus dnaJ subfamily B 0.0409 0.2914 0.2914
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0023 0.0023
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0305 0.2144 0.5138
Entamoeba histolytica cysteine proteinase, putative 0.0305 0.2144 0.5104
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0031 0.0036
Echinococcus multilocularis Protein lozenge 0.0056 0.0303 0.0303
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.011 0.0707 0.0821
Brugia malayi Dopamine receptor protein 2 0.0049 0.0255 0.0296
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0031 0.0036
Plasmodium vivax unspecified product 0.0305 0.2144 0.531
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Brugia malayi Cathepsin L-like precursor 0.0561 0.4038 0.4684
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0075
Echinococcus multilocularis protein dispatched 1 0.0047 0.0242 0.0242
Plasmodium vivax vivapain-3 0.0305 0.2144 0.531
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.066 0.158
Onchocerca volvulus 0.0049 0.0255 0.0631
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Giardia lamblia Cathepsin B precursor 0.0455 0.3255 0.78
Brugia malayi G-protein coupled receptor 0.0049 0.0255 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Plasmodium falciparum phd finger protein, putative 0.0031 0.0123 0.0304
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0035 0.004
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0031 0.0031
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0042 0.0101
Echinococcus granulosus cathepsin L 0.0305 0.2144 0.2144
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.004 0.004
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0255 0.0255
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.0047 0.0239 0.0278
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0029 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0695 0.1666
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0071 0.0071
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0109 0.0261
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.016 0.0397
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0074
Entamoeba histolytica cysteine protease, putative 0.013 0.0853 0.1989
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0238 0.0238
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0063 0.0074
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0352 0.0352
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0063 0.032
Schistosoma mansoni opsin-like receptor 0.0049 0.0255 0.0255
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0109 0.027
Trypanosoma cruzi ISWI complex protein 0.0015 0.0005 0.0006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.004 0.0047
Schistosoma mansoni amine GPCR 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0047 0.0239 0.0278
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0255 0.0255
Brugia malayi CHE-14 protein 0.0041 0.0199 0.0231
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0065 0.0163
Brugia malayi RE15519p 0.0049 0.0255 0.0296
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0695 0.0806
Echinococcus granulosus orexin receptor type 2 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0031 0.0075
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0239 0.0593
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0109 0.027
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0561 0.4038 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni hypothetical protein 0.0104 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.004 0.0047
Plasmodium vivax vivapain-2 0.0561 0.4038 1
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0255 0.0255
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0113 0.0113
Entamoeba histolytica hypothetical protein 0.0023 0.0063 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0561 0.4038 0.9675
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.013 0.0853 0.2044
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0255 0.0255
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0063 0.0157
Brugia malayi Serotonin receptor 0.0049 0.0255 0.0296
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0255 0.0255
Entamoeba histolytica cysteine proteinase, putative 0.0561 0.4038 0.9673
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.004 0.0047
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0432 0.1071
Brugia malayi AKH receptor 0.0049 0.0255 0.0296
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0695 0.3504
Schistosoma mansoni hypothetical protein 0.0409 0.2914 0.2914
Echinococcus multilocularis cpg binding protein 0.0032 0.013 0.013
Trichomonas vaginalis glucose transporter, putative 0.0032 0.013 0.0312
Onchocerca volvulus 0.002 0.004 0.0099
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0255 0.0255
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0305 0.2144 0.2144
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0065 0.0161
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0073 0.0432 0.1071
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0204
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0914 0.0914
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Brugia malayi cathepsin B-like cysteine proteinase 0.1181 0.862 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0352 0.0352
Echinococcus granulosus cysteine protease 0.0305 0.2144 0.2144
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0031
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0035 0.0035
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0031 0.0031
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Loa Loa (eye worm) hypothetical protein 0.013 0.0853 0.099
Toxoplasma gondii cathepsin B 0.0455 0.3255 0.8062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Trichomonas vaginalis glucose transporter, putative 0.0032 0.013 0.0312
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0695 0.3504
Loa Loa (eye worm) hypothetical protein 0.0443 0.3164 0.367
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0122 0.0122
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0029 0.0071
Brugia malayi cathepsin L-like cysteine proteinase 0.013 0.0853 0.099
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.016 0.0397
Brugia malayi neuropeptide F receptor 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0063 0.0133
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0492 0.0492
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0036
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0063 0.0063
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0305 0.2144 0.2487
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.013 0.0853 0.099
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Trypanosoma cruzi cruzipain precursor, putative 0.0561 0.4038 0.4684
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.1181 0.862 1
Brugia malayi hypothetical protein 0.0122 0.0797 0.0925
Loa Loa (eye worm) glutamate receptor 0.0122 0.0792 0.0919
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0305 0.2144 0.531
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0029 0.0144
Schistosoma mansoni hypothetical protein 0.0049 0.0255 0.0255
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0046 0.0046
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.004 0.0047
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0127 0.0315
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.004 0.004
Echinococcus granulosus metabotropic glutamate receptor 2 0.0102 0.0646 0.0646
Echinococcus granulosus cathepsin b 0.1181 0.862 0.862
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0158 0.0158
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0122 0.0142
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0239 0.1207
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0018 0.0018
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0029 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0255 0.0255
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0352 0.0352
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0213 0.0213
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0255 0.0296
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0695 0.1666
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0046 0.0046
Entamoeba histolytica cysteine protease, putative 0.013 0.0853 0.1989
Plasmodium vivax serine-repeat antigen (SERA), putative 0.013 0.0853 0.2113
Schistosoma mansoni amine GPCR 0.0049 0.0255 0.0255
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0065 0.0161
Trypanosoma cruzi cruzipain precursor, putative 0.0175 0.1183 0.1373
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0153 0.0153
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0255 0.0255
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0695 0.1608
Brugia malayi Cam kinase protein 1 0.0032 0.0127 0.0147
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.013 0.0322
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0239 0.1207
Brugia malayi fibroinase precursor 0.013 0.0853 0.099
Onchocerca volvulus 0.0049 0.0255 0.0631
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.004 0.0047
Schistosoma mansoni hypothetical protein 0.0205 0.1405 0.1405
Schistosoma mansoni zinc finger protein 0.0015 0.0005 0.0005
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0109 0.027
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0036
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0109 0.027
Echinococcus granulosus cathepsin L cysteine protease 0.0305 0.2144 0.2144
Trypanosoma brucei glucose transporter 2A 0.0032 0.013 0.0322
Echinococcus multilocularis metabotropic glutamate receptor 5 0.015 0.1 0.1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0455 0.3255 0.78
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0035 0.0035
Giardia lamblia Cathepsin B precursor 0.013 0.0853 0.2044
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0647 0.0647
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0255 0.0255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0065 0.0327
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0031 0.0031
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0109 0.5174
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0122 0.0122
Echinococcus multilocularis cathepsin L 0.013 0.0853 0.0853
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0152 0.0176
Echinococcus granulosus expressed conserved protein 0.0091 0.0564 0.0564
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.004 0.0047
Leishmania major glucose transporter, lmgt2 0.0032 0.013 0.0322
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0035 0.0086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0137 0.0693
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0561 0.4038 0.9675
Plasmodium falciparum cysteine proteinase falcipain 3 0.0561 0.4038 1
Trypanosoma cruzi cysteine peptidase, putative 0.0561 0.4038 0.4684
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0432 0.0502
Leishmania major glucose transporter, lmgt3 0.0032 0.013 0.0322
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0029 0.0071
Echinococcus granulosus cathepsin b 0.1181 0.862 0.862
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0455 0.3255 0.3776
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.0268 0.0311
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0255 0.0255
Brugia malayi Cathepsin L-like precursor 0.0175 0.1183 0.1373
Echinococcus multilocularis expressed protein 0.0367 0.2602 0.2602
Brugia malayi Cathepsin L-like precursor 0.0386 0.2747 0.3186
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0127 0.0315
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Loa Loa (eye worm) hypothetical protein 0.0044 0.0219 0.0254
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0123 0.0123
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0063 0.0157
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0255 0.0255
Onchocerca volvulus 0.0049 0.0255 0.0631
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.016 0.0397
Schistosoma mansoni myosin xvIII 0.0049 0.0255 0.0255
Echinococcus granulosus neuropeptide receptor A26 0.0049 0.0255 0.0255
Trypanosoma brucei ISWI complex protein 0.0015 0.0005 0.0013
Giardia lamblia Cysteine protease 0.013 0.0853 0.2044
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.03 0.03
Plasmodium vivax CDK-related protein kinase 6, putative 0.0441 0.3149 0.78
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0255 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0261
Brugia malayi Cathepsin L-like precursor 0.0561 0.4038 0.4684
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0109 0.027
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0063 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.004 0.004
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0255 0.0255
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0305 0.2144 0.2144
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0255 0.0255
Echinococcus granulosus hypothetical protein 0.0049 0.0255 0.0255
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0255 0.0255
Brugia malayi PHD-finger family protein 0.0027 0.0088 0.0102
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0073 0.0432 0.0502
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0031 0.0122 0.0142
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0127 0.0315
Echinococcus multilocularis cathepsin b 0.1181 0.862 0.862
Schistosoma mansoni cathepsin s 0.0175 0.1183 0.1183
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0255 0.0296
Echinococcus multilocularis cysteine protease 0.0561 0.4038 0.4038
Echinococcus multilocularis tumor protein p63 0.0408 0.2909 0.2909
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0083 0.0506 0.0587
Onchocerca volvulus 0.0049 0.0255 0.0631
Brugia malayi Cathepsin L-like cysteine proteinase 0.0386 0.2747 0.3186
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0255 0.0255
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0049 0.0255 0.0296
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0047
Echinococcus granulosus expressed protein 0.0367 0.2602 0.2602
Loa Loa (eye worm) cathepsin B 0.0455 0.3255 0.3776
Schistosoma mansoni amine GPCR 0.0049 0.0255 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0075
Trypanosoma cruzi hexose transporter 0.0032 0.013 0.0151
Trypanosoma cruzi cysteine proteinase, putative 0.0305 0.2144 0.2487
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0026
Trypanosoma cruzi hexose transporter, putative 0.0032 0.013 0.0151
Schistosoma mansoni hypothetical protein 0.0049 0.0255 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.004 0.0047
Trypanosoma cruzi cysteine peptidase, putative 0.0561 0.4038 0.4684
Onchocerca volvulus 0.0049 0.0255 0.0631
Brugia malayi CXXC zinc finger family protein 0.0029 0.0104 0.0121
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0127 0.0315
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni neuropeptide receptor 0.0049 0.0255 0.0255
Plasmodium falciparum cysteine proteinase falcipain 1 0.0305 0.2144 0.531
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0122 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.013 0.0853 0.2044
Onchocerca volvulus 0.0049 0.0255 0.0631
Echinococcus multilocularis General substrate transporter 0.0089 0.0552 0.0552
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0029 0.0071
Onchocerca volvulus 0.0049 0.0255 0.0631
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0695 0.0695
Brugia malayi hypothetical protein 0.0035 0.0153 0.0178
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0035 0.004
Giardia lamblia PHD finger protein 15 0.0031 0.0123 0.0294
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0031 0.0031
Echinococcus granulosus g protein coupled receptor 0.0049 0.0255 0.0255
Entamoeba histolytica hypothetical protein 0.0035 0.0153 0.0301
Schistosoma mansoni cpg binding protein 0.0029 0.0104 0.0104
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0046 0.0053
Echinococcus granulosus ubiquitin specific protease 41 0.0073 0.0432 0.0432
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0386 0.2747 0.3186
Loa Loa (eye worm) hypothetical protein 0.0035 0.0152 0.0176
Giardia lamblia Cathepsin L precursor 0.013 0.0853 0.2044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0036
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.066 0.1633
Brugia malayi PXA domain containing protein 0.0019 0.0031 0.0036
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0035 0.0083
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.016 0.0397
Loa Loa (eye worm) hypothetical protein 0.0561 0.4038 0.4684
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.004 0.004
Onchocerca volvulus 0.0049 0.0255 0.0631
Loa Loa (eye worm) hypothetical protein 0.013 0.0853 0.099
Brugia malayi Papain family cysteine protease containing protein 0.0561 0.4038 0.4684
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0283 0.1983 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Echinococcus granulosus peregrin 0.0034 0.014 0.014
Schistosoma mansoni DNA polymerase eta 0.0019 0.0035 0.0035
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Leishmania major DNA polymerase eta, putative 0.0019 0.0035 0.0086
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0122 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.013 0.0853 0.2044
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0255 0.0296
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0197 0.0197
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0261
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0023 0.0026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0104 0.0121
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0283 0.1983 1
Plasmodium falciparum protein kinase 6 0.0441 0.3149 0.78
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0695 0.0695
Giardia lamblia Cathepsin L-like protease 0.013 0.0853 0.2044
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.004 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0853 0.2044
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0102 0.0646 0.0646
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0065 0.0327
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0984 0.1141
Brugia malayi sulfakinin receptor protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0031 0.0122 0.0142
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0197 0.0229
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0137 0.0693
Entamoeba histolytica cysteine proteinase, putative 0.0305 0.2144 0.5104
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0046 0.0053
Onchocerca volvulus Bile acid receptor homolog 0.002 0.004 0.0099
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1181 0.862 0.862
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.013 0.0312
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Echinococcus granulosus cathepsin l cysteine peptidase 0.0561 0.4038 0.4038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0352 0.0408
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0031 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0018 0.0018
Giardia lamblia Cathepsin L precursor 0.013 0.0853 0.2044
Onchocerca volvulus 0.0561 0.4038 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.004 0.0047
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0109 0.027
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Brugia malayi Sugar transporter family protein 0.0104 0.066 0.0765
Trypanosoma cruzi cysteine peptidase, putative 0.0305 0.2144 0.2487
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0255 0.0255
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0122 0.0122
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0029 0.0029
Onchocerca volvulus 0.0049 0.0255 0.0631
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.004 0.004
Schistosoma mansoni cathepsin C 0.013 0.0853 0.0853
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0255 0.0255
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0255 0.0255
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0153 0.0153
Brugia malayi Melatonin receptor type 1A 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.0443 0.3164 0.367
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0073 0.0432 0.0432
Plasmodium falciparum serine repeat antigen 7 0.013 0.0853 0.2113
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0127 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0305 0.2144 0.5138
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0239 0.1207
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0239 0.0278
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0199 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0073 0.0432 0.0432
Brugia malayi ecdysteroid receptor 0.002 0.004 0.0047
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0255 0.0255
Mycobacterium ulcerans hypothetical protein 0.0047 0.0239 0.1207
Schistosoma mansoni cathepsin F (C01 family) 0.0561 0.4038 0.4038
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1181 0.862 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0506 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0199 0.0476
Toxoplasma gondii cathepsin CPC1 0.013 0.0853 0.2113
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0152 0.0375
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0168 0.1132 0.2804
Giardia lamblia Dipeptidyl-peptidase I precursor 0.013 0.0853 0.2044
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0239 0.1037
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0018 0.0018
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0029 0.0068
Leishmania major cathepsin L-like protease 0.0561 0.4038 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0238 0.0276
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0255 0.0255
Trypanosoma cruzi hexose transporter, putative 0.0032 0.013 0.0151
Schistosoma mansoni hypothetical protein 0.0035 0.0153 0.0153
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0695 0.1608
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0255 0.0255
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0607 0.1395
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.013 0.0853 0.2113
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0031 0.0036
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.013 0.0853 0.0853
Entamoeba histolytica papain family cysteine protease domain containing protein 0.013 0.0853 0.1989
Trichomonas vaginalis sugar transporter, putative 0.0032 0.013 0.0312
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Loa Loa (eye worm) hypothetical protein 0.013 0.0853 0.099
Onchocerca volvulus Huntingtin homolog 0.0122 0.0797 0.1974
Brugia malayi GnHR receptor homolog 0.0049 0.0255 0.0296
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0127 0.0315
Giardia lamblia Dipeptidyl-peptidase I precursor 0.013 0.0853 0.2044
Entamoeba histolytica cysteine protease, putative 0.013 0.0853 0.1989
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0035 0.0086
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0239 0.1207
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0188
Plasmodium falciparum serine repeat antigen 3 0.013 0.0853 0.2113
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Schistosoma mansoni neuropeptide receptor 0.0049 0.0255 0.0255
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0255 0.0255
Onchocerca volvulus 0.0049 0.0255 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.013 0.0853 0.2113
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.0147
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0255 0.0255
Giardia lamblia Cathepsin B precursor 0.013 0.0853 0.2044
Echinococcus multilocularis GPCR, family 3, C terminal 0.002 0.0038 0.0038
Brugia malayi neuropeptide F receptor 0.0049 0.0255 0.0296
Brugia malayi steroid hormone receptor 0.002 0.004 0.0047
Plasmodium falciparum serine repeat antigen 5 0.013 0.0853 0.2113
Toxoplasma gondii cathepsin CPL 0.0561 0.4038 1
Schistosoma mansoni hypothetical protein 0.0047 0.0238 0.0238
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0127 0.0127
Giardia lamblia Cathepsin L precursor 0.013 0.0853 0.2044
Brugia malayi cathepsin L-like precursor 0.0386 0.2747 0.3186
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0031 0.0031
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Leishmania major cysteine peptidase A (CPA) 0.0561 0.4038 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0036
Echinococcus multilocularis cathepsin L cysteine protease 0.0561 0.4038 0.4038
Schistosoma mansoni thyroid hormone receptor 0.002 0.004 0.004
Echinococcus multilocularis serotonin receptor 0.0049 0.0255 0.0255
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1181 0.862 0.862
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.03 0.03
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0695 0.1608
Loa Loa (eye worm) hypothetical protein 0.0041 0.0199 0.0231
Giardia lamblia Cysteine protease 0.013 0.0853 0.2044
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0618 0.0618
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0137 0.0693
Echinococcus granulosus cathepsin l1 0.0386 0.2747 0.2747
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.004 0.004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0255 0.0255
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0255 0.0255
Onchocerca volvulus 0.0083 0.0506 0.1254
Treponema pallidum fructose-bisphosphate aldolase 0.0579 0.4173 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0109 0.5174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.013 0.0853 0.2044
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Trypanosoma brucei glucose transporter, putative 0.0032 0.013 0.0322
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0255 0.0255
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0109 0.0194
Echinococcus granulosus serotonin receptor 0.0049 0.0255 0.0255
Onchocerca volvulus 0.0049 0.0255 0.0631
Schistosoma mansoni adenoreceptor 0.0049 0.0255 0.0255
Brugia malayi nuclear receptor NHR-88 0.002 0.004 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0561 0.4038 1
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0045
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0152 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.004 0.0047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0175 0.1183 0.1373
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0152 0.0764
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0255 0.0296
Entamoeba histolytica protein kinase, putative 0.0032 0.0127 0.0238
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0352 0.0408
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0073 0.0432 0.1036
Entamoeba histolytica cysteine proteinase, putative 0.0305 0.2144 0.5104
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0101 0.0638 0.0638
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0213 0.0213
Brugia malayi Bromodomain containing protein 0.0034 0.014 0.0162
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0255 0.0296
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0113 0.0113
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0239 0.0509
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0255 0.0255
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0239 0.0278
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0506 0.0506
Onchocerca volvulus 0.013 0.0853 0.2113
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.013 0.0853 0.2113
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0071 0.0071
Onchocerca volvulus 0.0561 0.4038 1
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.004 0.0047
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0035 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0031 0.0075
Giardia lamblia Cathepsin L-like protease 0.013 0.0853 0.2044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.2747 0.6581
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0607 0.0607
Brugia malayi Papain family cysteine protease containing protein 0.013 0.0853 0.099
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0029 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0086
Entamoeba histolytica cysteine protease, putative 0.0305 0.2144 0.5104
Loa Loa (eye worm) sugar transporter 0.0104 0.066 0.0765
Brugia malayi phosphofructokinase 0.0109 0.0695 0.0806
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.013 0.0853 0.2044
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0031 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0305
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0255 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0109 0.0261
Toxoplasma gondii cathepsin CPC2 0.013 0.0853 0.2113
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0695 0.1666
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.004 0.0047
Schistosoma mansoni cathepsin B (C01 family) 0.013 0.0853 0.0853
Trichomonas vaginalis sugar transporter, putative 0.0032 0.013 0.0312
Loa Loa (eye worm) hypothetical protein 0.0122 0.0797 0.0925
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0255 0.0255
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0029 0.0068
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0109 0.027
Echinococcus granulosus GPCR family 2 0.0047 0.0238 0.0238
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0914 0.0914
Giardia lamblia Hypothetical protein 0.013 0.0853 0.2044
Plasmodium falciparum hexose transporter 0.0104 0.066 0.1633
Echinococcus granulosus FTZ F1 alpha 0.002 0.004 0.004
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.2914 0.2914
Brugia malayi hypothetical protein 0.0049 0.0255 0.0296
Trypanosoma cruzi cysteine protease, putative 0.0305 0.2144 0.2487
Schistosoma mansoni patched 1 0.0041 0.0199 0.0199
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0255 0.0255
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0352 0.0408
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0127 0.0315
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.013 0.0853 0.2113
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.016 0.0186
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.066 0.066
Onchocerca volvulus Cathepsin L homolog 0.0561 0.4038 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0063 0.0152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Plasmodium falciparum serine repeat antigen 8 0.013 0.0853 0.2113
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.03 0.0349
Echinococcus granulosus cathepsin L 0.013 0.0853 0.0853
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0035 0.004
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis ubiquitin specific protease 41 0.0073 0.0432 0.0432
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0031 0.0031
Echinococcus multilocularis expressed conserved protein 0.0091 0.0564 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0561 0.4038 0.9675
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0255 0.0255
Schistosoma mansoni hypothetical protein 0.0047 0.0238 0.0238
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0073 0.0432 0.0432
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0199 0.0231
Echinococcus granulosus neuropeptide receptor 0.0049 0.0255 0.0255
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0035 0.0175
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0031 0.0031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.013 0.0853 0.0853
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0255 0.0255
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.013 0.0853 0.0853
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0255 0.0255
Trypanosoma cruzi hexose transporter, putative 0.0032 0.013 0.0151
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0239 0.1207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0386 0.2747 0.6581
Loa Loa (eye worm) fibroinase 0.0561 0.4038 0.4684
Schistosoma mansoni cathepsin F (C01 family) 0.0561 0.4038 0.4038
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0122 0.0293
Trypanosoma cruzi cysteine peptidase, putative 0.0175 0.1183 0.1373
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0063 0.0157
Brugia malayi nuclear hormone receptor 0.002 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0296
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0695 0.0695
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0255 0.0255
Schistosoma mansoni biogenic amine receptor 0.0049 0.0255 0.0255
Brugia malayi follicle stimulating hormone receptor 0.0049 0.0255 0.0296
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0127 0.0147
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0561 0.4038 0.4038
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0455 0.3255 0.8062
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0255 0.0631
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0579 0.4173 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0239 0.1037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0561 0.4038 0.9675
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0031 0.0031
Trypanosoma cruzi cysteine proteinase, putative 0.0305 0.2144 0.2487
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0035 0.0086
Schistosoma mansoni hypothetical protein 0.0047 0.0238 0.0238
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0255 0.0255
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0255 0.0255

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0041 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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