Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.4584 | 1 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.0587 | 0.9326 | 0.5 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.0619 | 1 | 1 |
Toxoplasma gondii | cell division protein CDC48AP | 0.0371 | 0.4742 | 0.0000097958 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0587 | 0.9326 | 0.9296 |
Mycobacterium ulcerans | ATPase | 0.0371 | 0.4742 | 0.5 |
Trypanosoma cruzi | Valosin-containing protein, putative | 0.0587 | 0.9326 | 0.5 |
Toxoplasma gondii | cell division protein CDC48CY | 0.0619 | 1 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0256 | 0.232 | 0.1979 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.0587 | 0.9326 | 1 |
Giardia lamblia | AAA family ATPase | 0.0371 | 0.4742 | 0.5 |
Leishmania major | Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog | 0.0587 | 0.9326 | 0.5 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0371 | 0.4742 | 0.5 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.0587 | 0.9326 | 0.5 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0619 | 1 | 1 |
Trypanosoma brucei | Valosin-containing protein | 0.0587 | 0.9326 | 0.5 |
Brugia malayi | vesicle-fusing ATPase | 0.0363 | 0.4584 | 1 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0619 | 1 | 1 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0363 | 0.4584 | 1 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.0619 | 1 | 0.5 |
Entamoeba histolytica | cdc48-like protein, putative | 0.0587 | 0.9326 | 0.5 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0256 | 0.232 | 0.1979 |
Brugia malayi | valosin containing protein | 0.0363 | 0.4584 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.