Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.154 | 0.7474 | 0.7295 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1529 | 0.741 | 0.7227 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0296 | 0.0662 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1529 | 0.741 | 0.741 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0296 | 0.0662 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.154 | 0.7474 | 0.7295 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.154 | 0.7474 | 0.7295 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1075 | 0.4929 | 0.457 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0908 | 0.4011 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0744 | 0.3113 | 0.5745 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.2002 | 1 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0296 | 0.0662 | 0.0662 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1032 | 0.4691 | 0.4315 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1529 | 0.741 | 0.7227 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.154 | 0.7474 | 0.7295 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0296 | 0.0662 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.154 | 0.7474 | 0.7295 |
Schistosoma mansoni | alpha-glucosidase | 0.1377 | 0.658 | 0.658 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0296 | 0.0662 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0296 | 0.0662 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0296 | 0.0662 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0296 | 0.0662 | 0.5 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1529 | 0.741 | 0.7227 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1529 | 0.741 | 0.7227 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1529 | 0.741 | 0.741 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1377 | 0.658 | 0.658 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1075 | 0.4929 | 0.457 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0744 | 0.3113 | 0.5745 |
Onchocerca volvulus | 0.0925 | 0.4108 | 0.1695 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | > 10 mM | Tested for binding activity against Selectin E of the compound; inactive | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.