Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0111 | 1 | 1 |
Echinococcus multilocularis | dual specificity | 0.0111 | 1 | 1 |
Trypanosoma brucei | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0111 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0111 | 1 | 1 |
Echinococcus granulosus | dual specificity | 0.0111 | 1 | 1 |
Echinococcus multilocularis | dual specificity | 0.0111 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0111 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0111 | 1 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0111 | 1 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK2 protein kinase | 0.0111 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0111 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0111 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0111 | 1 | 0.5 |
Echinococcus multilocularis | dual specificity | 0.0111 | 1 | 1 |
Giardia lamblia | Kinase, CMGC DYRK | 0.0111 | 1 | 0.5 |
Trypanosoma cruzi | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0111 | 1 | 1 |
Echinococcus granulosus | dual specificity | 0.0111 | 1 | 1 |
Echinococcus granulosus | dual specificity | 0.0111 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase DYRK2, putative | 0.0111 | 1 | 0.5 |
Leishmania major | protein kinase, putative,dual-specificity protein kinase, putative | 0.0111 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0111 | 1 | 0.5 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0093 | 0.0767 | 0.0767 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.