Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0118 | 0.153 | 0.3677 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0107 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0107 | 0.1367 | 0.2609 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.006 | 0.0669 | 0.0669 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0217 | 0.4201 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0065 | 0.075 | 0.075 |
Onchocerca volvulus | Alhambra homolog | 0.002 | 0.0084 | 0.112 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1745 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0024 | 0.0146 | 0.0186 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0029 | 0.0037 |
Mycobacterium ulcerans | lipase LipD | 0.0023 | 0.0125 | 0.0234 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0591 | 0.8496 | 0.8628 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0084 | 0.0107 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1745 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0054 | 0.058 | 0.1139 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0023 | 0.0125 | 0.0234 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0021 | 0.0107 | 0.0136 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0217 | 1 |
Echinococcus granulosus | peregrin | 0.002 | 0.0084 | 0.0084 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.000000012083 | 0.000000015415 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.002 | 0.0084 | 0.1228 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0118 | 0.153 | 0.3677 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0024 | 0.0146 | 0.0286 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0023 | 0.0125 | 0.0713 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0024 | 0.0146 | 0.0286 |
Toxoplasma gondii | ABC1 family protein | 0.0023 | 0.0125 | 0.2131 |
Brugia malayi | hypothetical protein | 0.012 | 0.1556 | 0.1985 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0293 | 0.4109 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0107 | 0.021 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.1359 | 0.2667 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0106 | 0.1355 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Brugia malayi | beta-lactamase family protein | 0.0023 | 0.0125 | 0.0159 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0064 | 0.0733 | 0.0935 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0024 | 0.0146 | 0.0148 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0217 | 1 |
Loa Loa (eye worm) | glutamate receptor | 0.0025 | 0.0162 | 0.0207 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0031 | 0.0253 | 0.0322 |
Brugia malayi | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1744 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.006 | 0.0669 | 0.0853 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.000000012083 | 0.000000023714 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0477 | 0.0477 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.2683 |
Onchocerca volvulus | 0.0023 | 0.0125 | 0.1659 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0023 | 0.0125 | 0.0713 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0293 | 0.4109 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0364 | 0.5158 | 1 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0546 | 0.7836 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0146 | 0.0186 |
Schistosoma mansoni | jumonji domain containing protein | 0.0052 | 0.0553 | 0.1085 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0024 | 0.0146 | 0.0146 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0023 | 0.0125 | 0.0234 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0118 | 0.153 | 0.3526 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.0859 | 0.0872 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0029 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0293 | 0.4109 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.328 |
Mycobacterium ulcerans | beta-lactamase | 0.0023 | 0.0125 | 0.0234 |
Brugia malayi | phosphofructokinase | 0.0107 | 0.1367 | 0.1744 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0364 | 0.5158 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0023 | 0.0125 | 0.0234 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0023 | 0.0125 | 0.0234 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.002 | 0.0084 | 0.1228 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0477 | 0.0484 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0029 | 0.0217 | 0.4201 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.006 | 0.0669 | 0.0669 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0477 | 0.0609 |
Onchocerca volvulus | 0.0065 | 0.0751 | 1 | |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0107 | 0.1367 | 0.1388 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0023 | 0.0125 | 0.0245 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.036 | 0.5095 | 0.5174 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0084 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0079 | 0.0951 | 0.0951 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0023 | 0.0125 | 0.0713 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.006 | 0.0669 | 0.1313 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0016 | 0.0033 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0751 | 0.1474 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.006 | 0.0669 | 0.1313 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0118 | 0.153 | 0.3677 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0031 | 0.0253 | 0.0322 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0054 | 0.058 | 0.0589 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0477 | 0.0609 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.2683 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0107 | 0.1367 | 0.3119 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Loa Loa (eye worm) | phosphofructokinase | 0.0107 | 0.1367 | 0.1745 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Mycobacterium tuberculosis | Probable reductase | 0.0106 | 0.1355 | 0.325 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0023 | 0.0125 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0751 | 0.1474 |
Echinococcus multilocularis | geminin | 0.0106 | 0.1359 | 0.138 |
Echinococcus multilocularis | peregrin | 0.002 | 0.0084 | 0.0085 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0054 | 0.058 | 0.058 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.075 | 0.0956 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.036 | 0.5095 | 0.6502 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0079 | 0.0951 | 0.0965 |
Loa Loa (eye worm) | hypothetical protein | 0.0479 | 0.6841 | 0.873 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0028 | 0.0199 | 0.0202 |
Giardia lamblia | PHD finger protein 15 | 0.002 | 0.0084 | 0.2924 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0031 | 0.0251 | 0.0492 |
Plasmodium vivax | hypothetical protein, conserved | 0.002 | 0.0084 | 0.1228 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0023 | 0.0125 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0951 | 0.1213 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.2131 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Brugia malayi | beta-lactamase | 0.0023 | 0.0125 | 0.0159 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.036 | 0.5095 | 0.5095 |
Echinococcus granulosus | jumonji domain containing protein | 0.0028 | 0.0199 | 0.0199 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0477 | 0.0873 |
Onchocerca volvulus | 0.0023 | 0.0125 | 0.1659 | |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0107 | 0.0136 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0364 | 0.5158 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.1359 | 0.2667 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0106 | 0.1355 | 0.325 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.002 | 0.0084 | 0.0084 |
Brugia malayi | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1744 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0477 | 0.0873 |
Loa Loa (eye worm) | beta-lactamase | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.036 | 0.5095 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0293 | 0.0374 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0364 | 0.5158 | 0.658 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0293 | 0.4109 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.006 | 0.0669 | 0.1313 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0029 | 0.003 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.000000012083 | 0.000000015415 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0023 | 0.0124 | 0.0126 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0106 | 0.1355 | 0.325 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0107 | 0.1367 | 0.2609 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.000000012083 | 0.00000001227 |
Mycobacterium tuberculosis | Conserved protein | 0.0023 | 0.0125 | 0.0234 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0217 | 0.4201 |
Mycobacterium tuberculosis | Conserved protein | 0.0023 | 0.0125 | 0.0234 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0073 | 0.0862 | 0.1692 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.439 | 0.5603 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.2534 | 0.3234 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0023 | 0.0125 | 0.0245 |
Brugia malayi | Bromodomain containing protein | 0.002 | 0.0084 | 0.0107 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0029 | 0.0057 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0477 | 1 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0029 | 0.0217 | 0.4201 |
Mycobacterium tuberculosis | Conserved protein | 0.0023 | 0.0125 | 0.0234 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.000000012083 | 0.000000012083 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.5158 | 0.6582 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.0217 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | glutamate receptor | 0.0064 | 0.0733 | 0.0936 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0023 | 0.0125 | 0.0234 |
Onchocerca volvulus | 0.0023 | 0.0125 | 0.1659 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.006 | 0.0669 | 0.0679 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0477 | 0.0873 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0477 | 1 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.0859 | 0.0859 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0107 | 0.1367 | 0.328 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0058 | 0.0645 | 0.0822 |
Brugia malayi | Protein kinase domain containing protein | 0.0546 | 0.7839 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0023 | 0.0124 | 0.0244 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0041 | 0.0396 | 0.0505 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0107 | 0.1367 | 0.1367 |
Brugia malayi | Serotonin receptor | 0.0465 | 0.6648 | 0.8481 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0023 | 0.0125 | 0.0713 |
Echinococcus multilocularis | MAM | 0.0065 | 0.0751 | 0.0762 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0477 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.006 | 0.0669 | 0.0854 |
Mycobacterium leprae | PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) | 0.0293 | 0.4109 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0023 | 0.0125 | 0.0713 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0683 | 0.9848 | 1 |
Echinococcus granulosus | geminin | 0.0106 | 0.1359 | 0.1359 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0124 | 0.0159 |
Brugia malayi | PHD-finger family protein | 0.002 | 0.0084 | 0.0107 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0031 | 0.0251 | 0.032 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0477 | 0.0609 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0106 | 0.1355 | 0.325 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0217 | 0.4201 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0023 | 0.0125 | 0.0234 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0029 | 0.0217 | 0.4201 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0477 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0029 | 0.5 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0106 | 0.1355 | 0.3088 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Plasmodium falciparum | phd finger protein, putative | 0.002 | 0.0084 | 0.1228 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0031 | 0.0253 | 0.0322 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.000000012083 | 0.000000015415 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0002 | 0.0003 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0253 | 0.0322 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0477 | 1 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0107 | 0.1367 | 1 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0016 | 0.0033 | 0.0042 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.0217 | 0.0748 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 0.1355 | 0.325 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.002 | 0.0084 | 0.0085 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0217 | 0.4201 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0023 | 0.0125 | 0.0125 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.036 | 0.5095 | 0.65 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0029 | 0.0217 | 0.1406 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0016 | 0.0033 | 0.0042 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0065 | 0.075 | 0.0761 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0124 | 0.0244 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0107 | 0.1367 | 0.2609 |
Echinococcus granulosus | MAM | 0.0065 | 0.0751 | 0.0751 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0477 | 0.0609 |
Mycobacterium leprae | Isocitrate lyase | 0.0137 | 0.1815 | 0.4244 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0144 | 0.1919 | 0.4632 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0477 | 0.1098 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.006 | 0.0669 | 0.0679 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.002 | 0.0084 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0033 | 0.0042 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0023 | 0.0124 | 0.0124 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0293 | 0.4109 | 1 |
Onchocerca volvulus | 0.0065 | 0.0751 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 11.2 nM | Activity against [Ca2+]-ATPase in rabbit myocardial membrane | ChEMBL. | 7830270 |
RIC50 (binding) | = 0.85 | Inhibitory potency against sarco- endoplasmic reticulum calcium-ATPase in relative to thapsigargin | ChEMBL. | 15828839 |
RIC50 (binding) | = 0.85 | Inhibitory potency against sarco- endoplasmic reticulum calcium-ATPase in relative to thapsigargin | ChEMBL. | 15828839 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.