Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0036 | 0.2947 | 0.2666 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0036 | 0.2947 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2947 | 0.2947 |
Brugia malayi | YY1-associated factor 2 | 0.0036 | 0.2947 | 0.2666 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0101 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0101 | 1 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0036 | 0.2947 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0101 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0101 | 1 | 1 |
Schistosoma mansoni | brg-1 associated factor | 0.0101 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0101 | 1 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0383 | 0.0383 |
Brugia malayi | brahma associated protein 60 kDa | 0.0101 | 1 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0036 | 0.2947 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0036 | 0.2947 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0036 | 0.2947 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0036 | 0.2947 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0383 | 0.0383 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | brahma associated protein | 0.0101 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0012 | 0.0383 | 0.5 |
Chlamydia trachomatis | SWIB complex protein | 0.0101 | 1 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0101 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0036 | 0.2947 | 0.2666 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2947 | 0.2947 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0101 | 1 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0036 | 0.2947 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0036 | 0.2947 | 0.2666 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0101 | 1 | 1 |
Onchocerca volvulus | 0.0101 | 1 | 1 | |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0101 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 1 | 0.5 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0101 | 1 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0036 | 0.2947 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2947 | 0.2947 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2947 | 0.2947 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2947 | 0.2947 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0036 | 0.2947 | 0.2666 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0383 | 0.0383 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0101 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0101 | 1 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0036 | 0.2947 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0101 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.2947 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.