Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | V-type ATP synthase subunit B | 0.0103 | 0 | 0.5 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Trypanosoma cruzi | ATP synthase, epsilon chain, putative | 0.0181 | 0.2387 | 1 |
Echinococcus granulosus | mitochondrial F1F0 ATP synthase subunit epsilon | 0.0431 | 1 | 1 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit gamma | 0.0149 | 0.1405 | 0.2008 |
Echinococcus multilocularis | ATP synthase subunit delta, mitochondrial | 0.0181 | 0.2387 | 0.2387 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE EPSILON CHAIN ATPC | 0.0181 | 0.2387 | 0.1757 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE ALPHA CHAIN ATPA | 0.0332 | 0.6996 | 1 |
Leishmania major | ATPase alpha subunit | 0.0274 | 0.5201 | 1 |
Mycobacterium tuberculosis | Probable ATP synthase beta chain AtpD | 0.0332 | 0.6996 | 1 |
Trypanosoma cruzi | Mitochondrial ATP synthase epsilon chain, putative | 0.0146 | 0.1323 | 0.5544 |
Plasmodium falciparum | ATP synthase subunit delta, mitochondrial, putative | 0.0181 | 0.2387 | 0.2387 |
Trypanosoma brucei | mitochondrial ATP synthase delta chain | 0.0181 | 0.2387 | 0.4589 |
Plasmodium vivax | ATP synthase alpha chain, putative | 0.0332 | 0.6996 | 0.6996 |
Leishmania major | hypothetical protein, conserved | 0.0146 | 0.1323 | 0.2544 |
Schistosoma mansoni | ATP synthase alpha subunit mitochondrial | 0.0332 | 0.6996 | 0.6996 |
Plasmodium vivax | hypothetical protein, conserved | 0.0181 | 0.2387 | 0.2387 |
Treponema pallidum | flagellum-specific ATP synthase (fliI) | 0.0103 | 0 | 0.5 |
Chlamydia trachomatis | V-type ATP synthase subunit A | 0.0103 | 0 | 0.5 |
Trypanosoma brucei | ATP synthase F1, alpha subunit | 0.0274 | 0.5201 | 1 |
Mycobacterium tuberculosis | Probable ATP synthase alpha chain AtpA | 0.0332 | 0.6996 | 1 |
Schistosoma mansoni | ATP synthase delta chain mitochondrial | 0.0181 | 0.2387 | 0.2387 |
Trypanosoma cruzi | ATP synthase F1 subunit gamma protein, putative | 0.0149 | 0.1405 | 0.5885 |
Echinococcus multilocularis | ATP synthase subunit alpha, mitochondrial | 0.0332 | 0.6996 | 0.6996 |
Onchocerca volvulus | ATP synthase subunit alpha, mitochondrial homolog | 0.0332 | 0.6996 | 1 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE BETA CHAIN ATPD | 0.0332 | 0.6996 | 1 |
Plasmodium vivax | ATP synthase epsilon chain, mitochondrial , putative | 0.0431 | 1 | 1 |
Entamoeba histolytica | V-type ATPase, A subunit, putative | 0.0103 | 0 | 0.5 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Leishmania major | ATP synthase, epsilon chain, putative | 0.0181 | 0.2387 | 0.4589 |
Trypanosoma cruzi | ATP synthase F1 subunit gamma protein, putative | 0.0149 | 0.1405 | 0.5885 |
Trypanosoma brucei | ATP synthase F1, alpha subunit | 0.0274 | 0.5201 | 1 |
Echinococcus multilocularis | mitochondrial F1F0 ATP synthase subunit epsilon | 0.0431 | 1 | 1 |
Plasmodium vivax | ATP synthase subunit gamma, mitochondrial, putative | 0.0149 | 0.1405 | 0.1405 |
Echinococcus granulosus | 5'partial|ATP synthase subunit delta mitochondrial | 0.0181 | 0.2387 | 0.2387 |
Echinococcus granulosus | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Plasmodium falciparum | mitochondrial ATP synthase F1, epsilon subunit, putative | 0.0431 | 1 | 1 |
Giardia lamblia | Vacuolar ATP synthase subunit B | 0.0103 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0431 | 1 | 1 |
Trypanosoma brucei | ATP synthase F1 subunit gamma protein, putative | 0.0149 | 0.1405 | 0.2701 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Treponema pallidum | V-type ATP synthase subunit B | 0.0103 | 0 | 0.5 |
Loa Loa (eye worm) | ATP synthase subunit epsilon | 0.0431 | 1 | 1 |
Onchocerca volvulus | ATP synthase subunit delta, mitochondrial homolog | 0.0181 | 0.2387 | 0.1757 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit alpha | 0.0332 | 0.6996 | 1 |
Trichomonas vaginalis | ATP synthase, putative | 0.0103 | 0 | 0.5 |
Trypanosoma cruzi | Mitochondrial ATP synthase epsilon chain, putative | 0.0146 | 0.1323 | 0.5544 |
Treponema pallidum | V-type ATP synthase subunit A | 0.0103 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit alpha | 0.0332 | 0.6996 | 1 |
Echinococcus multilocularis | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Entamoeba histolytica | V-type ATPase, B subunit, putative | 0.0103 | 0 | 0.5 |
Trichomonas vaginalis | ATP synthase beta subunit, putative | 0.0103 | 0 | 0.5 |
Chlamydia trachomatis | type III secretion system ATPase | 0.0103 | 0 | 0.5 |
Brugia malayi | ATP synthase gamma chain, mitochondrial precursor, putative | 0.0149 | 0.1405 | 0.1405 |
Trypanosoma brucei | mitochondrial ATP synthase epsilon chain | 0.0146 | 0.1323 | 0.2544 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Plasmodium falciparum | ATP synthase F1, alpha subunit | 0.0332 | 0.6996 | 0.6996 |
Giardia lamblia | Vacuolar ATP synthase catalytic subunit A | 0.0103 | 0 | 0.5 |
Loa Loa (eye worm) | ATP synthase subunit delta | 0.0181 | 0.2387 | 0.2387 |
Trichomonas vaginalis | ATP synthase alpha subunit mitochondrial, putative | 0.0103 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit gamma | 0.0149 | 0.1405 | 0.2008 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit epsilon | 0.0181 | 0.2387 | 0.3412 |
Brugia malayi | ATP synthase delta chain, mitochondrial precursor, putative | 0.0181 | 0.2387 | 0.2387 |
Toxoplasma gondii | ATP synthase F1 gamma subunit | 0.0149 | 0.1405 | 0.1405 |
Leishmania major | ATP synthase F1 subunit gamma protein, putative | 0.0149 | 0.1405 | 0.2701 |
Mycobacterium tuberculosis | Probable ATP synthase epsilon chain AtpC | 0.0181 | 0.2387 | 0.1757 |
Brugia malayi | ATP synthase alpha chain, mitochondrial precursor, putative | 0.0332 | 0.6996 | 0.6996 |
Leishmania major | ATPase alpha subunit | 0.0274 | 0.5201 | 1 |
Treponema pallidum | V-type ATP synthase subunit B | 0.0103 | 0 | 0.5 |
Echinococcus granulosus | ATP synthase subunit alpha mitochondrial | 0.0332 | 0.6996 | 0.6996 |
Toxoplasma gondii | atp synthase F1, epsilon subunit, putative | 0.0431 | 1 | 1 |
Chlamydia trachomatis | type III secretion system ATP synthase | 0.0103 | 0 | 0.5 |
Plasmodium falciparum | ATP synthase subunit gamma, mitochondrial | 0.0149 | 0.1405 | 0.1405 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1405 | 0.1405 |
Treponema pallidum | V-type ATP synthase subunit A | 0.0103 | 0 | 0.5 |
Toxoplasma gondii | ATP synthase, putative | 0.0181 | 0.2387 | 0.2387 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit epsilon | 0.0181 | 0.2387 | 0.3412 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.