Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.0784 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.1116 | 0.2161 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0033 | 0.0621 | 0.0621 |
Plasmodium vivax | amine transporter, putative | 0.0033 | 0.0621 | 0.4619 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.1116 | 0.3907 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0595 | 0.0595 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0104 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0361 | 0.0456 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0257 | 0.0257 |
Plasmodium falciparum | transporter, putative | 0.0033 | 0.0621 | 0.4619 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0536 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0015 | 0.0167 | 0.0167 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.1116 | 0.2161 |
Trichomonas vaginalis | mgm1, putative | 0.0022 | 0.0361 | 0.3356 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0195 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0033 | 0.0621 | 0.0621 |
Toxoplasma gondii | dynamin-related protein DRPA | 0.0022 | 0.0361 | 0.0788 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0361 | 0.0389 |
Brugia malayi | RNA, U transporter 1 | 0.0086 | 0.1963 | 0.5396 |
Trypanosoma brucei | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0595 | 0.0595 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0104 |
Trypanosoma cruzi | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0.0702 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0059 | 0.1275 | 0.1275 |
Onchocerca volvulus | 0.0033 | 0.0621 | 0.1706 | |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0022 | 0.0361 | 0.0788 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0033 | 0.0621 | 0.0621 |
Schistosoma mansoni | cpg binding protein | 0.0062 | 0.1359 | 0.1359 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.3638 | 0.4595 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.4419 | 0.4419 |
Echinococcus multilocularis | dynamin | 0.0022 | 0.0361 | 0.0361 |
Echinococcus granulosus | geminin | 0.0184 | 0.4419 | 0.4419 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0033 | 0.0621 | 0.0621 |
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0561 | 0.0561 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0595 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1116 | 0.141 |
Schistosoma mansoni | hypothetical protein | 0.0407 | 1 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0257 | 0.0257 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0391 | 0.0391 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0033 | 0.0621 | 0.5 |
Echinococcus multilocularis | snurportin 1 | 0.0324 | 0.7919 | 0.7919 |
Schistosoma mansoni | cpg binding protein | 0.0062 | 0.1359 | 0.1359 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0324 | 0.7919 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1706 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.1116 | 1 |
Plasmodium vivax | dynamin protein, putative | 0.0022 | 0.0361 | 0.1798 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0033 | 0.0621 | 0.5 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0033 | 0.0621 | 0.0621 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0361 | 0.0389 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0195 |
Echinococcus granulosus | serotonin transporter | 0.0033 | 0.0621 | 0.0621 |
Plasmodium falciparum | amino acid transporter, putative | 0.0033 | 0.0621 | 0.4619 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.1116 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0167 | 0.0167 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0561 | 0.3977 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0195 | 0.0195 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1706 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1861 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0808 | 1 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0621 | 0.1706 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0595 | 0.0595 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0595 | 0.0751 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0418 | 0.0522 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0808 | 0.1437 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0418 | 0.4203 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1861 |
Echinococcus granulosus | dynamin 1 | 0.0024 | 0.0404 | 0.0404 |
Echinococcus multilocularis | geminin | 0.0184 | 0.4419 | 0.4419 |
Trypanosoma cruzi | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Toxoplasma gondii | dynamin-related protein DRPB | 0.0022 | 0.0361 | 0.0788 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0195 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0033 | 0.0621 | 0.0621 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0059 | 0.1275 | 0.161 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0033 | 0.0621 | 0.0621 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0216 | 0.5214 | 0.5214 |
Plasmodium falciparum | dynamin-like protein | 0.0022 | 0.0361 | 0.1798 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.0621 | 0.4619 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0418 | 0.1275 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0033 | 0.0621 | 0.0621 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0418 | 0.4203 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0033 | 0.0621 | 0.0621 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0808 | 0.0808 |
Onchocerca volvulus | 0.0033 | 0.0621 | 0.1706 | |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0033 | 0.0621 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0015 | 0.0167 | 0.0167 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0595 | 0.0595 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0361 | 0.0361 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0808 | 0.1437 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.1116 | 0.2161 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0561 | 0.0859 |
Echinococcus granulosus | cpg binding protein | 0.0062 | 0.1359 | 0.1359 |
Toxoplasma gondii | hypothetical protein | 0.0033 | 0.0621 | 0.1861 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0361 | 0.0991 |
Trypanosoma cruzi | dynamin-1-like protein | 0.0022 | 0.0361 | 0.0389 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0216 | 0.5214 | 0.5214 |
Schistosoma mansoni | ran | 0.0022 | 0.0361 | 0.0361 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1706 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0561 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0536 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0216 | 0.5214 | 0.5214 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.4419 | 0.4419 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0808 | 1 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0361 | 0.1798 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.231 | 0.2917 |
Trichomonas vaginalis | dynamin, putative | 0.0022 | 0.0361 | 0.3356 |
Echinococcus multilocularis | dynamin 1 protein | 0.0022 | 0.0361 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.5214 | 0.6584 |
Trypanosoma brucei | dynamin-1-like protein | 0.0022 | 0.0361 | 0.0389 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0808 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0808 | 0.0808 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0808 | 1 |
Trichomonas vaginalis | dynamin, putative | 0.0022 | 0.0361 | 0.3356 |
Leishmania major | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0033 | 0.0621 | 0.0621 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0808 | 0.0808 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1861 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0808 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0125 | 0.2926 | 0.2926 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0033 | 0.0621 | 0.0784 |
Onchocerca volvulus | 0.0059 | 0.1275 | 0.3503 | |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0033 | 0.0621 | 0.0621 |
Echinococcus multilocularis | serotonin transporter | 0.0033 | 0.0621 | 0.0621 |
Brugia malayi | S-adenosyl-methionine cycloartenol-C24-methyltransferase | 0.0091 | 0.2071 | 0.5692 |
Brugia malayi | hypothetical protein | 0.0034 | 0.065 | 0.1787 |
Trypanosoma brucei | sterol 24-c-methyltransferase, putative | 0.0097 | 0.223 | 0.4773 |
Trichomonas vaginalis | interferon-induced GTP-binding protein mx, putative | 0.0022 | 0.0361 | 0.3356 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0361 | 0.0361 |
Trichomonas vaginalis | dynamin, putative | 0.0022 | 0.0361 | 0.3356 |
Echinococcus multilocularis | cpg binding protein | 0.0062 | 0.1359 | 0.1359 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0561 | 0.1617 |
Echinococcus multilocularis | dynamin 1 | 0.0024 | 0.0404 | 0.0404 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0216 | 0.5214 | 0.5214 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0595 | 0.0595 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0595 | 0.0595 |
Schistosoma mansoni | hypothetical protein | 0.0324 | 0.7919 | 0.7919 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0808 | 0.1437 |
Toxoplasma gondii | hypothetical protein | 0.0033 | 0.0621 | 0.1861 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0022 | 0.0361 | 0.1798 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0808 | 0.1437 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0361 | 0.0389 |
Echinococcus granulosus | dynamin 1 protein | 0.0022 | 0.0361 | 0.0361 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0195 |
Brugia malayi | Dynamin | 0.0024 | 0.0404 | 0.111 |
Schistosoma mansoni | dynamin | 0.0024 | 0.0404 | 0.0404 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0216 | 0.5214 | 0.5214 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.231 | 0.6349 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0418 | 0.0522 |
Brugia malayi | hypothetical protein | 0.0052 | 0.1116 | 0.3069 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0033 | 0.0621 | 0.0621 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.1706 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.0391 | 0.0391 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0033 | 0.0621 | 0.0621 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0033 | 0.0621 | 0.0621 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0808 | 0.102 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.0391 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0561 | 0.1543 |
Brugia malayi | Inositol-1 | 0.004 | 0.0808 | 0.222 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0195 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0111 | 0.2593 | 1 |
Schistosoma mansoni | dynamin | 0.0024 | 0.0404 | 0.0404 |
Trypanosoma brucei | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0702 | 1 |
Trypanosoma brucei | dynamin-1-like protein | 0.0022 | 0.0361 | 0.0389 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0808 | 0.0808 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0033 | 0.0621 | 0.0621 |
Loa Loa (eye worm) | DRP-1 protein | 0.0022 | 0.0361 | 0.0456 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0246 |
Leishmania major | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Entamoeba histolytica | Ran family GTPase | 0.0022 | 0.0361 | 0.0001 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.1116 | 0.2161 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0033 | 0.0621 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1516 | 0.1915 |
Brugia malayi | Dynamin central region family protein | 0.0022 | 0.0361 | 0.0991 |
Trichomonas vaginalis | dynamin, putative | 0.0022 | 0.0361 | 0.3356 |
Plasmodium vivax | dynamin-like protein, putative | 0.0022 | 0.0361 | 0.1798 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0808 | 0.2632 |
Trypanosoma brucei | Sterol methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0361 | 0.0389 |
Onchocerca volvulus | 0.0153 | 0.3638 | 1 | |
Schistosoma mansoni | ran | 0.0022 | 0.0361 | 0.0361 |
Plasmodium falciparum | dynamin-like protein | 0.0022 | 0.0361 | 0.1798 |
Loa Loa (eye worm) | serotonin transporter b | 0.0033 | 0.0621 | 0.0784 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0033 | 0.0621 | 0.0621 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0808 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0561 | 0.0709 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0033 | 0.0621 | 0.1706 |
Onchocerca volvulus | 0.0033 | 0.0621 | 0.1706 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0595 | 0.0595 |
Trichomonas vaginalis | dynamin, putative | 0.0022 | 0.0361 | 0.3356 |
Trichomonas vaginalis | ran, putative | 0.0022 | 0.0361 | 0.3357 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.231 | 0.6349 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0015 | 0.0167 | 0.0167 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0561 | 0.0859 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0361 | 0.0389 |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0561 | 0.0561 |
Trypanosoma cruzi | sterol 24-c-methyltransferase, putative | 0.0186 | 0.4459 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.5214 | 0.6584 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0404 | 0.051 |
Echinococcus granulosus | snurportin 1 | 0.0324 | 0.7919 | 0.7919 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0595 | 0.0595 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.1116 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0033 | 0.0621 | 0.0621 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0595 | 0.1635 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1516 | 0.1516 |
Brugia malayi | Dynamin | 0.0024 | 0.0404 | 0.111 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0033 | 0.0621 | 0.0784 |
Schistosoma mansoni | dynamin | 0.0022 | 0.0361 | 0.0361 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0418 | 0.4203 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0167 | 0.0167 |
Brugia malayi | CXXC zinc finger family protein | 0.0059 | 0.1275 | 0.3503 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0033 | 0.0621 | 0.0784 |
Trichomonas vaginalis | dynamin, putative | 0.0022 | 0.0361 | 0.3356 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.2071 | 0.2615 |
Echinococcus granulosus | dynamin | 0.0022 | 0.0361 | 0.0361 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0407 | 1 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0195 | 0.0195 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0595 | 0.0595 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0012 | 0.0012 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0251 | 0.069 |
Brugia malayi | hypothetical protein | 0.0153 | 0.3638 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.231 | 0.2917 |
Onchocerca volvulus | 0.0033 | 0.0621 | 0.1706 | |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0595 | 0.0595 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0361 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0595 | 0.0751 |
Loa Loa (eye worm) | histone methyltransferase | 0.0018 | 0.0257 | 0.0324 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.1516 | 0.4167 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0621 | 0.0784 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0561 | 0.3977 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | = 40 uM | Cytotoxicity against human HEL cells 3 days by coulter counting | ChEMBL. | 22137458 |
CC50 (functional) | >= 250 uM | Cytotoxicity against human HeLa cells 3 days by coulter counting | ChEMBL. | 22137458 |
CC50 (functional) | > 250 uM | Cytotoxicity against human CEM cells 3 days by coulter counting | ChEMBL. | 22137458 |
CC50 (functional) | >= 250 uM | Cytotoxicity against mouse L1210 cells 2 days by coulter counting | ChEMBL. | 22137458 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.