Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.3322 | 0.5448 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0131 | 0.3919 | 0.7641 |
Onchocerca volvulus | AMP deaminase 2 homolog | 0.0054 | 0.1522 | 0.2079 |
Mycobacterium ulcerans | cytidine deaminase | 0.0052 | 0.1453 | 0.2768 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0054 | 0.1522 | 0.3585 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0086 | 0.2512 | 0.2512 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.0131 | 0.3919 | 0.7786 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0231 | 0.0231 |
Brugia malayi | Globin family protein | 0.0008 | 0.0094 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0103 | 0.0169 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0166 | 0.5004 | 0.7149 |
Mycobacterium leprae | PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) | 0.0052 | 0.1453 | 0.0545 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0405 | 0.0809 |
Brugia malayi | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.0481 | 0.0481 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0166 | 0.5004 | 1 |
Plasmodium falciparum | AMP deaminase, putative | 0.0054 | 0.1522 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.0086 | 0.251 | 0.492 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0143 | 0.0235 |
Plasmodium falciparum | adenosine deaminase | 0.0166 | 0.5004 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0405 | 0.0596 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0104 | 0.00000000024618 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0231 | 0.0379 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0143 | 0.0235 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.775 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0143 | 0.0286 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0405 | 0.0633 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0009 | 0.0104 | 0.0104 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0405 | 0.0329 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0209 | 0.0343 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0018 | 0.0403 | 0.061 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0041 | 0.1103 | 0.2465 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0143 | 0.0286 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0104 | 0.0171 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0209 | 0.0343 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0143 | 0.0286 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0737 | 0.1291 |
Echinococcus granulosus | adenosine deaminase | 0.0166 | 0.5004 | 0.5004 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0131 | 0.3919 | 0.779 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.0052 | 0.1453 | 0.2768 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0737 | 0.1473 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0405 | 0.0809 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.0481 | 0.0481 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0012 | 0.0209 | 0.0234 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0143 | 0.0143 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0143 | 0.0235 |
Toxoplasma gondii | AMP deaminase | 0.0054 | 0.1522 | 0.2893 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0131 | 0.3919 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0131 | 0.3919 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0143 | 0.0143 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.1522 | 0.2908 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0231 | 0.0231 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0143 | 0.0235 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0041 | 0.1103 | 0.1809 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0009 | 0.0104 | 0.0104 |
Leishmania major | AMP deaminase, putative,adenosine monophosphate deaminase-like protein | 0.0054 | 0.1522 | 0.2908 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0011 | 0.0182 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1327 | 0.2176 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0737 | 0.1209 |
Brugia malayi | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0143 | 0.0235 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Brugia malayi | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | AMP deaminase | 0.0054 | 0.1522 | 0.2496 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0143 | 0.0235 |
Mycobacterium ulcerans | adenosine deaminase | 0.0166 | 0.5004 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2512 | 0.412 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.775 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0351 | 0.0576 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0737 | 0.0737 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0166 | 0.5004 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0143 | 0.0235 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0166 | 0.5004 | 0.8207 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0131 | 0.3919 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1522 | 0.2496 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0405 | 0.0664 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0143 | 0.0286 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0143 | 0.0235 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0143 | 0.0286 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.065 | 0.065 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0166 | 0.5004 | 1 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.0052 | 0.1453 | 0.3401 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0143 | 0.0143 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Brugia malayi | adenosine monophosphate deaminase | 0.0054 | 0.1522 | 0.2496 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0104 | 0.0171 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0045 | 0.1246 | 0.2044 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0143 | 0.0235 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0143 | 0.0143 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0131 | 0.3919 | 0.779 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.0052 | 0.1453 | 0.2753 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0086 | 0.2512 | 0.3437 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.0052 | 0.1453 | 0.3401 |
Schistosoma mansoni | globin X | 0.0008 | 0.0094 | 0.0188 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | globin family protein | 0.0008 | 0.0094 | 0.0155 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0166 | 0.5004 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0143 | 0.0235 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0131 | 0.3919 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0143 | 0.0235 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0405 | 0.0462 |
Echinococcus multilocularis | cytidine deaminase | 0.0052 | 0.1453 | 0.1453 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Treponema pallidum | adenosine deaminase | 0.0166 | 0.5004 | 1 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0086 | 0.2512 | 0.2512 |
Entamoeba histolytica | cytidine deaminase, putative | 0.0052 | 0.1453 | 0.2636 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.065 | 0.065 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0041 | 0.1103 | 0.2465 |
Entamoeba histolytica | AMP deaminase, putative | 0.0054 | 0.1522 | 0.2778 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.3322 | 0.5448 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0131 | 0.3919 | 0.779 |
Giardia lamblia | Cytidine deaminase | 0.0052 | 0.1453 | 0.3536 |
Schistosoma mansoni | adenosine deaminase | 0.0166 | 0.5004 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0166 | 0.5004 | 0.7112 |
Trypanosoma brucei | cytidine deaminase | 0.0052 | 0.1453 | 0.3401 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.065 | 0.065 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 1 |
Onchocerca volvulus | 0.001 | 0.0143 | 0.0071 | |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.0481 | 0.0441 |
Entamoeba histolytica | AMP deaminase, putative | 0.0054 | 0.1522 | 0.2778 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.5512 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0086 | 0.251 | 0.6306 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0405 | 0.0633 |
Plasmodium vivax | adenosine deaminase, putative | 0.0166 | 0.5004 | 1 |
Leishmania major | adenosine monophosphate deaminase, putative,AMP deaminase, putative | 0.0054 | 0.1522 | 0.2908 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.0086 | 0.2512 | 0.412 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0143 | 0.0143 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0143 | 0.0143 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0143 | 0.0235 |
Trypanosoma brucei | cytochrome P450, putative | 0.0012 | 0.0209 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | globin family protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus granulosus | AMP deaminase 2 | 0.0054 | 0.1522 | 0.1522 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0143 | 0.0286 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0086 | 0.2512 | 0.3437 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0131 | 0.3919 | 1 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0131 | 0.3919 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.065 | 0.13 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0405 | 0.0614 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0405 | 0.0596 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0131 | 0.3919 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0143 | 0.0235 |
Onchocerca volvulus | 0.0029 | 0.0737 | 0.0936 | |
Brugia malayi | intermediate filament protein | 0.0026 | 0.065 | 0.1067 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0143 | 0.0143 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0143 | 0.0235 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0209 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0737 | 0.1209 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.6098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.3322 | 0.5448 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.2655 | 0.4355 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0216 | 0.0354 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0143 | 0.0143 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0045 | 0.1248 | 0.2351 |
Onchocerca volvulus | 0.0052 | 0.1453 | 0.1979 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0143 | 0.0235 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.065 | 0.1067 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.0481 | 0.0789 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.7706 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0131 | 0.3919 | 0.3919 |
Schistosoma mansoni | AMP deaminase | 0.0054 | 0.1522 | 0.3041 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.0086 | 0.2512 | 0.412 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus multilocularis | musashi | 0.0026 | 0.065 | 0.065 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0143 | 0.0143 |
Onchocerca volvulus | 0.0026 | 0.065 | 0.081 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0737 | 0.1473 |
Onchocerca volvulus | 0.0054 | 0.1522 | 0.2079 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0143 | 0.0286 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0086 | 0.251 | 0.6229 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.065 | 0.1067 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.2655 | 0.4355 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0143 | 0.0235 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0143 | 0.0071 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0209 | 0.0343 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0014 | 0.0268 | 0.0334 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0166 | 0.5004 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.0009 | 0.0104 | 0.0208 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.1327 | 0.2651 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0131 | 0.3919 | 1 |
Leishmania major | AMP deaminase, putative,amp deaminase-like protein | 0.0054 | 0.1522 | 0.2908 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.3322 | 0.5448 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0086 | 0.251 | 0.6229 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.5512 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0405 | 0.0614 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0166 | 0.5004 | 0.7112 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0131 | 0.3919 | 0.7832 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0737 | 0.1473 |
Onchocerca volvulus | 0.0052 | 0.1453 | 0.1979 | |
Leishmania major | AMP deaminase, putative | 0.0054 | 0.1522 | 0.2908 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0405 | 0.0405 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0737 | 0.1473 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0209 | 0.0234 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.0131 | 0.3919 | 0.7786 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0143 | 0.0143 |
Leishmania major | adenine aminohydrolase | 0.0166 | 0.5004 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0737 | 0.0737 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0636 | 0.1042 |
Trichomonas vaginalis | set domain proteins, putative | 0.0229 | 0.6962 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0008 | 0.0094 | 0.0188 |
Schistosoma mansoni | lamin | 0.0026 | 0.065 | 0.13 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0143 | 0.0235 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0131 | 0.3919 | 0.3919 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0131 | 0.3919 | 0.6427 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0405 | 0.0329 |
Onchocerca volvulus | 0.0229 | 0.6962 | 1 | |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0737 | 0.098 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0143 | 0.0235 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0143 | 0.0143 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0143 | 0.0143 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0041 | 0.1103 | 0.2465 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0131 | 0.3919 | 0.7832 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0209 | 0.0343 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0704 | 0.0704 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0143 | 0.0071 |
Echinococcus multilocularis | AMP deaminase 2 | 0.0054 | 0.1522 | 0.1522 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.5512 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0045 | 0.1246 | 0.1569 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0052 | 0.1453 | 0.1875 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0405 | 0.0596 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0131 | 0.3919 | 0.7832 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0274 | 0.0449 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0143 | 0.0286 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0405 | 0.0788 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0131 | 0.3919 | 0.3919 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.5512 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0209 | 0.0072 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0086 | 0.251 | 0.6229 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0143 | 0.0286 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0143 | 0.0235 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0131 | 0.3919 | 0.3919 |
Leishmania major | cytidine deaminase-like protein | 0.0052 | 0.1453 | 0.2768 |
Brugia malayi | Globin family protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0737 | 0.0737 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0143 | 0.0235 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.5512 |
Echinococcus multilocularis | tumor protein p63 | 0.0327 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.5004 | 0.8207 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.065 | 0.13 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0143 | 0.0235 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0143 | 0.0143 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.0131 | 0.3919 | 0.7786 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0274 | 0.0449 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.6098 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0054 | 0.1522 | 0.3585 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 0.775 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0009 | 0.0104 | 0.0104 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0405 | 0.0633 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0143 | 0.0286 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0131 | 0.3919 | 0.7832 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.065 | 0.1067 |
Echinococcus granulosus | cytidine deaminase | 0.0052 | 0.1453 | 0.1453 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0104 | 0.0171 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0052 | 0.1453 | 0.1875 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0094 | 0.0155 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0041 | 0.1103 | 0.2465 |
Echinococcus granulosus | lamin | 0.0026 | 0.065 | 0.065 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0041 | 0.1103 | 0.2465 |
Onchocerca volvulus | 0.0026 | 0.065 | 0.081 | |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.0481 | 0.0789 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0143 | 0.0071 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0143 | 0.0235 |
Brugia malayi | Globin family protein | 0.0008 | 0.0094 | 0.0155 |
Echinococcus multilocularis | adenosine deaminase | 0.0166 | 0.5004 | 0.5004 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0016 | 0.0346 | 0.0692 |
Onchocerca volvulus | 0.0048 | 0.1327 | 0.1794 | |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0009 | 0.0104 | 0.0104 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0143 | 0.0143 |
Brugia malayi | cytidine deaminase, identical | 0.0052 | 0.1453 | 0.2383 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0143 | 0.0286 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.065 | 0.1067 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0.1522 | 0.3585 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.0481 | 0.0441 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0009 | 0.0104 | 0.0171 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0143 | 0.0235 |
Echinococcus multilocularis | lamin | 0.0026 | 0.065 | 0.065 |
Schistosoma mansoni | DNA helicase recq1 | 0.0009 | 0.0104 | 0.0208 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0131 | 0.3919 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0209 | 0.0343 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0405 | 0.0405 |
Brugia malayi | Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative | 0.0008 | 0.0094 | 0.0155 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0405 | 0.0664 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0143 | 0.0235 |
Plasmodium vivax | adenosine/AMP deaminase, putative | 0.0054 | 0.1522 | 0.2639 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0166 | 0.5004 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0143 | 0.0235 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0405 | 0.0278 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0143 | 0.0286 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0143 | 0.0286 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0131 | 0.3919 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0216 | 0.0354 |
Schistosoma mansoni | adenosine deaminase-related | 0.0166 | 0.5004 | 1 |
Schistosoma mansoni | myoglobin 1 | 0.0008 | 0.0094 | 0.0188 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 69 % | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 at 6.25 ug/mL by microplate alamar blue assay | ChEMBL. | 21937153 |
MIC (functional) | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 by microplate alamar blue assay | ChEMBL. | 21937153 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.