Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0011 | 0.2106 | 0.2106 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.0026 | 0.9307 | 0.5 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0028 | 1 | 1 |
Mycobacterium ulcerans | ATPase | 0.0017 | 0.4595 | 0.5 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.0026 | 0.9307 | 0.5 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.0026 | 0.9307 | 1 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0016 | 0.4433 | 1 |
Trypanosoma brucei | Valosin-containing protein | 0.0026 | 0.9307 | 0.5 |
Toxoplasma gondii | cell division protein CDC48AP | 0.0017 | 0.4595 | 0.0000097958 |
Giardia lamblia | AAA family ATPase | 0.0017 | 0.4595 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.4433 | 1 |
Brugia malayi | valosin containing protein | 0.0016 | 0.4433 | 1 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.0028 | 1 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0028 | 1 | 1 |
Leishmania major | Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog | 0.0026 | 0.9307 | 0.5 |
Toxoplasma gondii | cell division protein CDC48CY | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | VCP protein | 0.0011 | 0.2106 | 0.4749 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.0028 | 1 | 0.5 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0017 | 0.4595 | 0.5 |
Trypanosoma cruzi | Valosin-containing protein, putative | 0.0026 | 0.9307 | 0.5 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0011 | 0.2106 | 0.2106 |
Brugia malayi | vesicle-fusing ATPase | 0.0016 | 0.4433 | 1 |
Entamoeba histolytica | cdc48-like protein, putative | 0.0026 | 0.9307 | 0.5 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0026 | 0.9307 | 0.9307 |
Brugia malayi | transitional endoplasmic reticulum ATPase TER94, putative | 0.0011 | 0.2106 | 0.4749 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.