Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | hypothetical protein | 0.0352 | 0.5538 | 1 |
Plasmodium falciparum | aminopeptidase P | 0.0109 | 0.1153 | 1 |
Plasmodium vivax | M17 leucyl aminopeptidase, putative | 0.0118 | 0.1312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Chlamydia trachomatis | cytosol aminopeptidase | 0.0118 | 0.1312 | 1 |
Mycobacterium ulcerans | leucyl aminopeptidase | 0.0118 | 0.1312 | 0.2067 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0067 | 0.0401 | 0.0401 |
Trypanosoma brucei | Xaa-Pro aminopeptidase, putative | 0.0109 | 0.1153 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Echinococcus granulosus | xaa pro aminopeptidase | 0.0109 | 0.1153 | 0.6684 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0109 | 0.1153 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0067 | 0.0401 | 0.0401 |
Mycobacterium leprae | Probable cytosol aminopeptidase PepB | 0.0118 | 0.1312 | 0.2067 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0352 | 0.5538 | 1 |
Wolbachia endosymbiont of Brugia malayi | leucyl aminopeptidase | 0.0118 | 0.1312 | 1 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0109 | 0.1153 | 0.0351 |
Treponema pallidum | aminopeptidase P | 0.0109 | 0.1153 | 0.5 |
Echinococcus multilocularis | xaa pro aminopeptidase | 0.0109 | 0.1153 | 0.6684 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0109 | 0.1153 | 1 |
Leishmania major | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 0.007 | 0.0446 | 0.2012 |
Onchocerca volvulus | 0.0065 | 0.0354 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0091 | 0.0831 | 0.1164 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0268 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0831 | 0.0831 |
Entamoeba histolytica | aminopeptidase, putative | 0.0109 | 0.1153 | 0.0316 |
Toxoplasma gondii | leucyl aminopeptidase LAP | 0.0118 | 0.1312 | 1 |
Echinococcus granulosus | leucine aminopeptidase protein | 0.0118 | 0.1312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Mycobacterium tuberculosis | Probable aminopeptidase PepB | 0.0118 | 0.1312 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0831 | 0.0831 |
Mycobacterium ulcerans | hypothetical protein | 0.0352 | 0.5538 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0599 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Mycobacterium tuberculosis | Conserved protein | 0.0352 | 0.5538 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0091 | 0.0831 | 1 |
Trypanosoma cruzi | aminopeptidase P1, putative | 0.0109 | 0.1153 | 1 |
Echinococcus multilocularis | leucine aminopeptidase protein | 0.0118 | 0.1312 | 1 |
Toxoplasma gondii | creatinase domain-containing protein | 0.0109 | 0.1153 | 0.6684 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0091 | 0.0831 | 0.1164 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0831 | 0.0831 |
Mycobacterium leprae | conserved hypothetical protein | 0.0352 | 0.5538 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0091 | 0.0831 | 0.1164 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0352 | 0.5538 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.