Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | biogenic amine receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | g protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | g protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0132 | 0.1995 | 0.198 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0895 | 0.077 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0588 | 1 | 1 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5645 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | fmrfamide receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0135 | 0.0117 |
Echinococcus granulosus | somatostatin receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | amine GPCR | 0.004 | 0.0372 | 0.0136 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0135 | 0.0424 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0588 | 1 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0158 | 0.2453 | 0.4284 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Brugia malayi | RNA binding protein | 0.007 | 0.0906 | 0.0781 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0135 | 0.0424 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0334 | 0.5544 | 1 |
Brugia malayi | AKH receptor | 0.004 | 0.0372 | 0.024 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0334 | 0.5544 | 1 |
Brugia malayi | TAR-binding protein | 0.007 | 0.0906 | 0.0781 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0209 | 0.3348 | 0.3256 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5645 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0588 | 1 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.004 | 0.0372 | 0.024 |
Leishmania major | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3348 | 0.3335 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0588 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | amine GPCR | 0.004 | 0.0372 | 0.0136 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5645 |
Chlamydia trachomatis | SWIB complex protein | 0.0588 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0057 | 0.068 | 0.0358 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0135 | 0.0424 |
Echinococcus multilocularis | fmrfamide receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | orexin receptor type 2 | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0588 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Onchocerca volvulus | 0.0209 | 0.3348 | 0.3256 | |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | fusion | 0.0209 | 0.3348 | 0.3185 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0895 | 0.0877 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.004 | 0.0372 | 0.0354 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0209 | 0.3348 | 0.3185 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0588 | 1 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.0906 | 0.0683 |
Brugia malayi | Serotonin receptor | 0.004 | 0.0372 | 0.024 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.0906 | 0.0889 |
Echinococcus granulosus | neuropeptide Y receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0588 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0135 | 0.0424 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0588 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.004 | 0.0372 | 0.024 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0209 | 0.3348 | 0.2907 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0209 | 0.3348 | 0.3185 |
Schistosoma mansoni | myosin xvIII | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.1459 | 0.1342 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | larval opioid receptor | 0.004 | 0.0372 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0239 | 0.0221 |
Schistosoma mansoni | histamine h1 receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.004 | 0.0372 | 0.0136 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0209 | 0.3348 | 0.5645 |
Brugia malayi | ORL1-like opioid receptor | 0.004 | 0.0372 | 0.024 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0209 | 0.3348 | 0.5645 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.004 | 0.0372 | 0.0354 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0209 | 0.3348 | 0.3185 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0176 | 0.2766 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Onchocerca volvulus | 0.0209 | 0.3348 | 0.3256 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.1459 | 0.1342 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0135 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0588 | 1 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | neuropeptide F receptor | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | g protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | opsin-like receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0158 | 0.2453 | 0.3871 |
Echinococcus granulosus | neuropeptides capa receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | zinc finger protein | 0.0209 | 0.3348 | 0.3185 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.0906 | 0.0781 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0135 | 0.0117 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0334 | 0.5544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Brugia malayi | neuropeptide F receptor | 0.004 | 0.0372 | 0.024 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0906 | 0.0683 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0239 | 0.0221 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | somatostatin receptor | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.004 | 0.0372 | 0.024 |
Brugia malayi | Dopamine receptor | 0.004 | 0.0372 | 0.024 |
Brugia malayi | G-protein coupled receptor | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.004 | 0.0372 | 0.0136 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0588 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0906 | 0.0683 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0209 | 0.3348 | 0.3185 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.004 | 0.0372 | 0.024 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | allatostatin A receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0588 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Brugia malayi | Serotonin receptor | 0.004 | 0.0372 | 0.024 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0135 | 0.5 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.1459 | 0.1443 |
Plasmodium vivax | hypothetical protein, conserved | 0.0588 | 1 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0209 | 0.3348 | 0.3335 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3348 | 0.3335 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0588 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0906 | 0.0683 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | neuropeptide Y receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Brugia malayi | hypothetical protein | 0.004 | 0.0372 | 0.024 |
Leishmania major | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5939 |
Schistosoma mansoni | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus granulosus | allatostatin A receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.004 | 0.0372 | 0.0354 |
Leishmania major | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0209 | 0.3348 | 0.5645 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | g-protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | sulfakinin receptor protein | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | hypothetical protein | 0.004 | 0.0372 | 0.0136 |
Toxoplasma gondii | ran binding protein | 0.0209 | 0.3348 | 0.2907 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0239 | 0.0105 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Echinococcus granulosus | neuropeptide s receptor | 0.004 | 0.0372 | 0.0136 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5645 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3348 | 0.3335 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Mycobacterium ulcerans | hypothetical protein | 0.0176 | 0.2766 | 1 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Brugia malayi | Dopamine receptor protein 2 | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0209 | 0.3348 | 0.3185 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.004 | 0.0372 | 0.0354 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | serotonin receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | amine GPCR | 0.004 | 0.0372 | 0.0136 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0135 | 0.5 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0588 | 1 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0895 | 0.0671 |
Schistosoma mansoni | amine GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0588 | 1 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | G-protein coupled receptor | 0.004 | 0.0372 | 0.024 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Schistosoma mansoni | RNA binding protein | 0.0209 | 0.3348 | 0.3185 |
Schistosoma mansoni | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0588 | 1 | 1 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Schistosoma mansoni | adenoreceptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | G protein-coupled receptor | 0.004 | 0.0372 | 0.024 |
Brugia malayi | RE15519p | 0.004 | 0.0372 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.0906 | 0.0889 |
Echinococcus granulosus | sex peptide receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1459 | 0.1443 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | TYRA-2 protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.004 | 0.0372 | 0.0136 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0135 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | Dopamine receptor protein 1 | 0.004 | 0.0372 | 0.024 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.004 | 0.0372 | 0.0136 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0019 | 0.0068 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.004 | 0.0372 | 0.0354 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0209 | 0.3348 | 0.5645 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus multilocularis | orexin receptor type 2 | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0209 | 0.3348 | 0.5645 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0209 | 0.3348 | 0.3256 |
Echinococcus multilocularis | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0135 | 0.0424 |
Onchocerca volvulus | 0.0209 | 0.3348 | 0.3256 | |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0906 | 0.0683 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | opsin-like receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | biogenic amine receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0209 | 0.3348 | 0.3185 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | fmrfamide receptor | 0.004 | 0.0372 | 0.0136 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0135 | 0.0489 |
Brugia malayi | GnHR receptor homolog | 0.004 | 0.0372 | 0.024 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0209 | 0.3348 | 0.3185 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0135 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus granulosus | g protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | 0.0588 | 1 | 1 | |
Schistosoma mansoni | opsin-like receptor | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0209 | 0.3348 | 0.3256 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0906 | 0.0683 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0588 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | putative neuropeptide receptor | 0.004 | 0.0372 | 0.024 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0209 | 0.3348 | 0.5645 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0209 | 0.3348 | 0.5645 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3348 | 0.3335 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.0906 | 0.0889 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | biogenic amine receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0209 | 0.3348 | 0.3256 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5645 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | neuropeptide s receptor | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Schistosoma mansoni | hypothetical protein | 0.0209 | 0.3348 | 0.3185 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.004 | 0.0372 | 0.0354 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.004 | 0.0372 | 0.0136 |
Onchocerca volvulus | 0.0209 | 0.3348 | 0.3256 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0239 | 0.0105 |
Schistosoma mansoni | amine GPCR | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0135 | 0.0117 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.004 | 0.0372 | 0.024 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.3348 | 0.3335 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0588 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Schistosoma mansoni | brg-1 associated factor | 0.0588 | 1 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0209 | 0.3348 | 0.3185 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.004 | 0.0372 | 0.0354 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.004 | 0.0372 | 0.024 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0135 | 0.0424 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0135 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.004 | 0.0372 | 0.024 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0209 | 0.3348 | 0.3185 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0135 | 0.0489 |
Echinococcus multilocularis | serotonin receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0132 | 0.1995 | 0.198 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0209 | 0.3348 | 0.5645 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0158 | 0.2453 | 0.3871 |
Brugia malayi | MH2 domain containing protein | 0.0132 | 0.1995 | 0.1885 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | brahma associated protein 60 kDa | 0.0588 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0334 | 0.5544 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0209 | 0.3348 | 0.5939 |
Echinococcus granulosus | neuropeptides capa receptor | 0.004 | 0.0372 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus multilocularis | sex peptide receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.004 | 0.0372 | 0.0136 |
Brugia malayi | YY1-associated factor 2 | 0.0209 | 0.3348 | 0.3256 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0135 | 0.0424 |
Onchocerca volvulus | 0.004 | 0.0372 | 0.024 | |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0209 | 0.3348 | 0.5645 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0372 | 0.0354 |
Echinococcus multilocularis | g protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0588 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0588 | 1 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0209 | 0.3348 | 0.3256 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.004 | 0.0372 | 0.0136 |
Echinococcus multilocularis | serotonin receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.0906 | 0.0683 |
Echinococcus granulosus | g protein coupled receptor | 0.004 | 0.0372 | 0.0136 |
Echinococcus granulosus | neuropeptide receptor | 0.004 | 0.0372 | 0.0136 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.957 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.912 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.911 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.887 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.88 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.839 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.816 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.803 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.771 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.768 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.735 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.