Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | 4-aminobutyrate aminotransferase | 0.0023 | 0.0024 | 0.0038 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0014 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0252 | 0.0572 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0115 | 0.1124 | 0.1781 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0034 | 0.0156 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.374 | 0.5923 |
Trichomonas vaginalis | glutaminase, putative | 0.0552 | 0.6315 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.0252 | 0.04 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0334 | 0.0529 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0083 | 0.0742 | 0.1176 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0188 | 0.1992 | 0.1992 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Toxoplasma gondii | NADP-dependent succinate-semialdehyde dehydrogenase | 0.004 | 0.0233 | 0.1061 |
Mycobacterium ulcerans | methyltransferase | 0.0045 | 0.0287 | 0.0454 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0071 | 0.0604 | 0.0956 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0195 | 0.2076 | 0.3287 |
Mycobacterium ulcerans | NAD-dependent aldehyde dehydrogenase AldA | 0.004 | 0.0233 | 0.0369 |
Schistosoma mansoni | thyroid hormone receptor | 0.0205 | 0.2194 | 0.3475 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0071 | 0.0604 | 0.1615 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0071 | 0.0604 | 0.0956 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0071 | 0.0604 | 0.1615 |
Trypanosoma cruzi | Thiopurine S-methyltransferase (TPMT), putative | 0.0045 | 0.0287 | 0.065 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0071 | 0.0604 | 0.1615 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.0575 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0036 | 0.0189 | 0.03 |
Schistosoma mansoni | alpha-glucosidase | 0.0162 | 0.1681 | 0.2662 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0014 | 0.0038 |
Trypanosoma brucei | Thiopurine S-methyltransferase (TPMT), putative | 0.0045 | 0.0287 | 0.4987 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0189 | 0.0506 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0014 | 0.0052 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | nuclear hormone receptor | 0.0034 | 0.0156 | 0.0247 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0059 | 0.0462 | 0.0732 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0176 | 0.1848 | 0.2926 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0042 | 0.0252 | 0.1155 |
Loa Loa (eye worm) | glutaminase | 0.0552 | 0.6315 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0334 | 0.0529 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0334 | 0.0529 |
Mycobacterium ulcerans | 4-aminobutyrate aminotransferase | 0.0023 | 0.0024 | 0.0038 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0071 | 0.0604 | 0.0956 |
Schistosoma mansoni | glutaminase | 0.0552 | 0.6315 | 1 |
Treponema pallidum | hypothetical protein | 0.0024 | 0.0036 | 0.2675 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0189 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0034 | 0.0156 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0038 | 0.0204 | 0.0323 |
Trypanosoma cruzi | aldehyde dehydrogenase, putative | 0.004 | 0.0233 | 0.0528 |
Mycobacterium tuberculosis | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 | 0.004 | 0.0233 | 0.0844 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0134 | 0.1347 | 0.36 |
Trypanosoma cruzi | Thiopurine S-methyltransferase (TPMT), putative | 0.0045 | 0.0287 | 0.065 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.0252 | 0.04 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0334 | 0.0893 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (small chain) | 0.0034 | 0.0156 | 0.0563 |
Schistosoma mansoni | zinc finger protein | 0.0034 | 0.0156 | 0.0247 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0195 | 0.2076 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0024 | 0.0038 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0014 | 0.0249 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0071 | 0.0604 | 0.0604 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0176 | 0.1848 | 0.2926 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0233 | 0.0369 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | DR-78 | 0.0034 | 0.0156 | 0.0247 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0189 | 0.0506 |
Echinococcus multilocularis | Aminotransferase class III | 0.0023 | 0.0024 | 0.0024 |
Brugia malayi | 4-aminobutyrate aminotransferase, mitochondrial precursor | 0.0253 | 0.2763 | 0.4375 |
Schistosoma mansoni | nuclear hormone receptor | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0071 | 0.0604 | 0.0956 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0034 | 0.0156 | 0.0156 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0038 | 0.0204 | 0.0323 |
Mycobacterium ulcerans | L-lysine aminotransferase | 0.0253 | 0.2763 | 0.4375 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0126 | 0.02 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.0575 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0138 | 0.1395 | 0.2208 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0189 | 0.03 |
Brugia malayi | tailless protein | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0071 | 0.0604 | 0.0956 |
Onchocerca volvulus | 0.0034 | 0.0156 | 0.0323 | |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0042 | 0.0252 | 0.04 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0334 | 0.0529 |
Schistosoma mansoni | nuclear hormone receptor | 0.0034 | 0.0156 | 0.0247 |
Brugia malayi | nuclear receptor NHR-67 | 0.0034 | 0.0156 | 0.0247 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0042 | 0.0252 | 0.4392 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0189 | 0.0189 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0188 | 0.1992 | 0.3155 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0042 | 0.0252 | 0.4392 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0083 | 0.0742 | 0.1176 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0042 | 0.0252 | 0.04 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.0575 | 0.1303 |
Brugia malayi | nuclear receptor NHR-88 | 0.0071 | 0.0604 | 0.0956 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0042 | 0.0252 | 0.04 |
Echinococcus granulosus | ornithine aminotransferase | 0.0023 | 0.0024 | 0.0065 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0071 | 0.0604 | 0.0956 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0071 | 0.0604 | 0.0956 |
Toxoplasma gondii | ornithine aminotransferase, mitochondrial precursor, putative | 0.0023 | 0.0024 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0014 | 0.0023 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0042 | 0.0252 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.0189 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0034 | 0.0156 | 0.0247 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0071 | 0.0604 | 0.0604 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0034 | 0.0156 | 0.0417 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0071 | 0.0604 | 0.0956 |
Mycobacterium ulcerans | adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 0.0023 | 0.0024 | 0.0038 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0042 | 0.0252 | 0.1216 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0071 | 0.0604 | 0.0956 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.0575 | 0.091 |
Schistosoma mansoni | nuclear receptor | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0126 | 0.02 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0034 | 0.0156 | 0.0156 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0014 | 0.0014 |
Trypanosoma brucei | glucosidase, putative | 0.0042 | 0.0252 | 0.4392 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0042 | 0.0252 | 0.04 |
Trichomonas vaginalis | acetylornithine aminotransferase, putative | 0.0023 | 0.0024 | 0.0038 |
Schistosoma mansoni | thyroid hormone receptor | 0.0205 | 0.2194 | 0.3475 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0034 | 0.0156 | 0.0156 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0034 | 0.0156 | 0.0417 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0188 | 0.1992 | 0.5326 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0038 | 0.0204 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Echinococcus multilocularis | succinate semialdehyde dehydrogenase | 0.004 | 0.0233 | 0.0233 |
Plasmodium vivax | ornithine aminotransferase, putative | 0.0023 | 0.0024 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0254 | 0.2779 | 0.44 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0023 | 0.0024 | 0.0024 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0071 | 0.0604 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0195 | 0.2076 | 0.3287 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0233 | 0.0369 |
Mycobacterium tuberculosis | Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) | 0.0023 | 0.0024 | 0.0087 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.004 | 0.023 | 0.023 |
Brugia malayi | nuclear receptor RXR | 0.0038 | 0.0204 | 0.0323 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0287 | 0.1381 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0126 | 0.02 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0134 | 0.1347 | 0.1347 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0036 | 0.0189 | 0.03 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0071 | 0.0604 | 0.1615 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0034 | 0.0156 | 0.0417 |
Mycobacterium ulcerans | glutamate-1-semialdehyde aminotransferase | 0.0023 | 0.0024 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | MH2 domain containing protein | 0.0138 | 0.1395 | 0.2208 |
Plasmodium falciparum | ornithine aminotransferase | 0.0023 | 0.0024 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0079 | 0.0692 | 0.1095 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0036 | 0.0189 | 0.03 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0038 | 0.0204 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Schistosoma mansoni | alpha-glucosidase | 0.0162 | 0.1681 | 0.2662 |
Leishmania major | aldehyde dehydrogenase, putative | 0.004 | 0.0233 | 0.1123 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0014 | 0.0249 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0034 | 0.0156 | 0.0247 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0034 | 0.0156 | 0.0247 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0071 | 0.0604 | 0.0956 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0083 | 0.0742 | 0.2687 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0069 | 0.0575 | 0.2768 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0071 | 0.0604 | 0.5175 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0692 | 0.1095 |
Echinococcus granulosus | GPCR family 2 | 0.0036 | 0.0189 | 0.0506 |
Mycobacterium ulcerans | NAD-dependent aldehyde dehydrogenase AldA | 0.004 | 0.0233 | 0.0369 |
Treponema pallidum | quinoline 2-oxidoreductase | 0.0028 | 0.0088 | 0.9035 |
Brugia malayi | nuclear hormone receptor | 0.0071 | 0.0604 | 0.0956 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.0575 | 0.1303 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0059 | 0.0462 | 0.0732 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.0252 | 0.04 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0034 | 0.0156 | 0.0417 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0077 | 0.0669 | 0.1789 |
Schistosoma mansoni | lamin | 0.0031 | 0.0126 | 0.02 |
Trypanosoma brucei | Thiopurine S-methyltransferase (TPMT), putative | 0.0045 | 0.0287 | 0.4987 |
Echinococcus multilocularis | GPCR, family 2 | 0.0036 | 0.0189 | 0.0189 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0071 | 0.0604 | 0.0956 |
Schistosoma mansoni | ornithine--oxo-acid transaminase | 0.0023 | 0.0024 | 0.0038 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0071 | 0.0604 | 0.1615 |
Loa Loa (eye worm) | glutaminase 2 | 0.0552 | 0.6315 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.1347 | 0.2132 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0115 | 0.1124 | 0.1781 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Mycobacterium ulcerans | succinate-semialdehyde dehydrogenase | 0.004 | 0.0233 | 0.0369 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0126 | 0.02 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0195 | 0.2076 | 0.2076 |
Mycobacterium tuberculosis | Conserved protein | 0.0045 | 0.0287 | 0.1037 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0071 | 0.0604 | 0.1615 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0052 | 0.0376 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0692 | 0.1095 |
Brugia malayi | glutaminase DH11.1 | 0.0552 | 0.6315 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0189 | 0.0189 |
Schistosoma mansoni | nuclear receptor | 0.0034 | 0.0156 | 0.0247 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0071 | 0.0604 | 0.5175 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0334 | 0.0334 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0138 | 0.1395 | 0.2208 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0042 | 0.0252 | 0.04 |
Echinococcus granulosus | succinate semialdehyde dehydrogenase | 0.004 | 0.0233 | 0.0623 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0071 | 0.0604 | 0.0956 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0205 | 0.2194 | 0.2194 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0014 | 0.0023 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0034 | 0.0156 | 0.0247 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0126 | 0.02 |
Brugia malayi | nuclear hormone receptor | 0.0034 | 0.0156 | 0.0247 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0038 | 0.0204 | 0.0323 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0334 | 0.0529 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0038 | 0.0204 | 0.0323 |
Echinococcus granulosus | transcription factor Dp 1 | 0.004 | 0.023 | 0.0615 |
Trypanosoma brucei | aldehyde dehydrogenase, putative | 0.004 | 0.0233 | 0.4057 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0126 | 0.0126 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0575 | 0.0575 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0071 | 0.0604 | 0.0956 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0034 | 0.0156 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0126 | 0.0126 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0059 | 0.0462 | 0.1674 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0195 | 0.2076 | 0.3287 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0034 | 0.0156 | 0.0417 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0014 | 0.0023 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0188 | 0.1992 | 0.3155 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0071 | 0.0604 | 0.1615 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Echinococcus granulosus | Aminotransferase class III | 0.0023 | 0.0024 | 0.0065 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0014 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase small chain CoxS | 0.0034 | 0.0156 | 0.0246 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0034 | 0.0156 | 0.0156 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0014 | 0.0023 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0071 | 0.0604 | 0.5175 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0014 | 0.0023 |
Brugia malayi | Succinate semialdehyde dehydrogenase, mitochondrial precursor | 0.004 | 0.0233 | 0.0369 |
Wolbachia endosymbiont of Brugia malayi | acetylornithine transaminase protein | 0.0023 | 0.0024 | 1 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0023 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | Probable aminotransferase | 0.0023 | 0.0024 | 0.0087 |
Brugia malayi | follicle stimulating hormone receptor | 0.0254 | 0.2779 | 0.44 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0071 | 0.0604 | 0.0604 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0071 | 0.0604 | 0.0956 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0115 | 0.1124 | 0.1781 |
Brugia malayi | steroid hormone receptor | 0.0071 | 0.0604 | 0.0956 |
Schistosoma mansoni | coup transcription factor | 0.0071 | 0.0604 | 0.0956 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0176 | 0.1848 | 0.2926 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0204 | 0.0323 |
Mycobacterium tuberculosis | Probable acetylornithine aminotransferase ArgD | 0.0023 | 0.0024 | 0.0087 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0071 | 0.0604 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Onchocerca volvulus | 0.0109 | 0.1049 | 1 | |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) | 0.004 | 0.0233 | 0.0844 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0014 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Echinococcus granulosus | lamin | 0.0031 | 0.0126 | 0.0338 |
Schistosoma mansoni | succinate semialdehyde dehydrogenase | 0.004 | 0.0233 | 0.0369 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0034 | 0.0156 | 0.0247 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0038 | 0.0204 | 0.0323 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0014 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Onchocerca volvulus | 0.0034 | 0.0156 | 0.0323 | |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0188 | 0.1992 | 0.1992 |
Schistosoma mansoni | lamin | 0.0031 | 0.0126 | 0.02 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0195 | 0.2076 | 0.3287 |
Trypanosoma cruzi | hypothetical protein | 0.0392 | 0.4411 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0042 | 0.0252 | 0.04 |
Mycobacterium tuberculosis | Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) | 0.0023 | 0.0024 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | ecdysone receptor | 0.0034 | 0.0156 | 0.0247 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0071 | 0.0604 | 0.0956 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0575 | 0.1536 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0034 | 0.0156 | 0.0323 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0071 | 0.0604 | 0.0956 |
Mycobacterium ulcerans | acetylornithine aminotransferase | 0.0023 | 0.0024 | 0.0038 |
Echinococcus multilocularis | geminin | 0.0335 | 0.374 | 0.374 |
Schistosoma mansoni | alpha glucosidase | 0.0042 | 0.0252 | 0.04 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.0252 | 0.04 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0071 | 0.0604 | 0.0604 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.1124 | 0.1781 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0071 | 0.0604 | 0.0956 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0195 | 0.2076 | 1 |
Mycobacterium tuberculosis | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 0.0023 | 0.0024 | 0.0087 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0189 | 0.03 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0071 | 0.0604 | 0.0956 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0071 | 0.0604 | 0.0604 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0252 | 0.0572 |
Echinococcus granulosus | geminin | 0.0335 | 0.374 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0071 | 0.0604 | 0.0956 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.0014 | 0.0023 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0042 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0071 | 0.0604 | 0.0604 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.374 | 0.5923 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0071 | 0.0604 | 0.0956 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0077 | 0.0669 | 0.0669 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0334 | 0.0893 |
Mycobacterium tuberculosis | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) | 0.0253 | 0.2763 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0604 | 0.0956 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0117 | 0.1142 | 0.1808 |
Mycobacterium leprae | PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD | 0.004 | 0.0233 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0071 | 0.0604 | 0.0604 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0195 | 0.2076 | 0.7514 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0126 | 0.02 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0195 | 0.2076 | 0.3287 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0071 | 0.0604 | 0.0956 |
Mycobacterium ulcerans | ornithine aminotransferase RocD1 and RocD2 | 0.0023 | 0.0024 | 0.0038 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0126 | 0.0338 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0071 | 0.0604 | 0.1615 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0195 | 0.2076 | 0.555 |
Brugia malayi | nuclear receptor RXR | 0.0034 | 0.0156 | 0.0247 |
Mycobacterium ulcerans | hypothetical protein | 0.0029 | 0.0096 | 0.0152 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase small chain CoxS | 0.0034 | 0.0156 | 0.0246 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0034 | 0.0156 | 0.0247 |
Treponema pallidum | hypothetical protein | 0.0029 | 0.0096 | 1 |
Chlamydia trachomatis | glutamate-1-semialdehyde-2,1-aminomutase | 0.0023 | 0.0024 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0334 | 0.0334 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0014 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0189 | 0.03 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.0575 | 0.091 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0071 | 0.0604 | 0.0604 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0071 | 0.0604 | 0.0956 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0189 | 0.03 |
Brugia malayi | ecdysteroid receptor | 0.0071 | 0.0604 | 0.0956 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.0575 | 0.091 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0034 | 0.0156 | 0.0323 |
Brugia malayi | nuclear receptor NHR-88 | 0.0034 | 0.0156 | 0.0247 |
Onchocerca volvulus | 0.0071 | 0.0604 | 0.5175 | |
Mycobacterium ulcerans | glutaminase | 0.0552 | 0.6315 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0071 | 0.0604 | 0.0956 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0126 | 0.0338 |
Echinococcus granulosus | FTZ F1 alpha | 0.0071 | 0.0604 | 0.1615 |
Echinococcus multilocularis | succinate semialdehyde dehydrogenase | 0.004 | 0.0233 | 0.0233 |
Brugia malayi | conserved hypotetical protein | 0.0034 | 0.0156 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0156 | 0.0247 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.0252 | 0.04 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0034 | 0.0156 | 0.0247 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | > 100 uM | Cytotoxicity against human MT4 cells after 96 hrs by MTT assay | ChEMBL. | 22047799 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.