Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.1191 | 0.367 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0044 | 0.037 | 0.0226 |
Echinococcus multilocularis | peregrin | 0.0058 | 0.058 | 0.0429 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0163 | 0.1655 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0044 | 0.037 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.2125 | 0.6546 |
Plasmodium vivax | hypothetical protein, conserved | 0.0058 | 0.058 | 0.5876 |
Brugia malayi | jmjC domain containing protein | 0.0191 | 0.2539 | 0.7824 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0044 | 0.037 | 0.0215 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.007 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.012 | 0.1497 | 0.4612 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.002 | 0.0016 | 0.0016 |
Brugia malayi | brahma associated protein 60 kDa | 0.0044 | 0.037 | 0.1139 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0694 | 1 | 1 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.003 | 0.0158 | 0.1601 |
Onchocerca volvulus | 0.0099 | 0.1184 | 0.3311 | |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0436 | 0.0436 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0044 | 0.037 | 0.3748 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0058 | 0.058 | 0.5876 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0184 | 0.0568 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0163 | 0.0503 |
Brugia malayi | Bromodomain containing protein | 0.0058 | 0.058 | 0.1786 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0184 | 0.0184 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0217 | 0.2934 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2921 | 0.8999 |
Trypanosoma brucei | polo-like protein kinase | 0.0093 | 0.1102 | 1 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0044 | 0.037 | 0.0226 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0184 | 0.0027 |
Echinococcus multilocularis | tumor protein p63 | 0.0676 | 0.9734 | 0.973 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.037 | 0.037 |
Schistosoma mansoni | brg-1 associated factor | 0.0044 | 0.037 | 0.037 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0163 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0163 | 0.2125 | 0.6546 |
Brugia malayi | Thioredoxin reductase | 0.0086 | 0.0987 | 0.304 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.007 | 0.0761 | 0.0613 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.007 | 0.0761 | 0.0761 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.003 | 0.0158 | 0.1601 |
Echinococcus granulosus | hormone sensitive lipase | 0.0216 | 0.2921 | 0.2815 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0195 | 0.2611 | 0.8837 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.003 | 0.0158 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0163 | 0.0163 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0022 | 0.0041 | 0.0127 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0044 | 0.037 | 0.1139 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.0761 | 0.2345 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0388 | 0.0388 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.037 | 0.037 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.1191 | 0.367 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0388 | 0.0245 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0093 | 0.1102 | 1 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0216 | 0.2921 | 0.2921 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.003 | 0.0158 | 0.1601 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.003 | 0.0158 | 0.0158 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.003 | 0.0158 | 0.1601 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0086 | 0.0994 | 0.086 |
Echinococcus granulosus | peregrin | 0.0058 | 0.058 | 0.0439 |
Treponema pallidum | NADH oxidase | 0.003 | 0.0158 | 0.5 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0191 | 0.2539 | 0.2428 |
Trypanosoma brucei | trypanothione reductase | 0.0086 | 0.0987 | 0.8956 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0058 | 0.058 | 0.1786 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.037 | 0.037 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0184 | 0.0184 |
Toxoplasma gondii | thioredoxin reductase | 0.0086 | 0.0987 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.2819 | 0.8687 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0184 | 0.0027 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.0438 | 0.1348 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0044 | 0.037 | 0.3748 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0238 | 0.3245 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.1102 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0151 | 0.196 | 0.196 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0184 | 0.0184 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0184 | 0.0568 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0184 | 0.0038 |
Onchocerca volvulus | Alhambra homolog | 0.0058 | 0.058 | 0.135 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0057 | 0.0564 | 0.0564 |
Leishmania major | trypanothione reductase | 0.0086 | 0.0987 | 0.8781 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0184 | 0.0184 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0388 | 0.1196 |
Loa Loa (eye worm) | glutathione reductase | 0.0086 | 0.0987 | 0.304 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0238 | 0.3245 | 1 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0044 | 0.037 | 0.3748 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0163 | 0.0163 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0086 | 0.0987 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0044 | 0.037 | 0.0215 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0093 | 0.1102 | 0.1102 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.003 | 0.0158 | 0.0487 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.003 | 0.0158 | 0.1434 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0184 | 0.0568 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0044 | 0.037 | 0.3748 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0217 | 0.2934 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0057 | 0.0564 | 0.0413 |
Giardia lamblia | PHD finger protein 15 | 0.0058 | 0.058 | 0.447 |
Giardia lamblia | Kinase, PLK | 0.0093 | 0.1102 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0191 | 0.2539 | 0.242 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.0725 | 0.2235 |
Brugia malayi | glutathione reductase | 0.0086 | 0.0987 | 0.304 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0388 | 0.0388 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.003 | 0.0158 | 0.1434 |
Brugia malayi | hypoxia-induced factor 1 | 0.015 | 0.1938 | 0.5972 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1195 | 0.3682 |
Echinococcus granulosus | jumonji domain containing protein | 0.0081 | 0.0917 | 0.0782 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0086 | 0.0994 | 0.085 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0163 | 0.0163 |
Plasmodium vivax | glutathione reductase, putative | 0.0086 | 0.0987 | 1 |
Brugia malayi | PHD-finger family protein | 0.0058 | 0.058 | 0.1786 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0086 | 0.0987 | 0.2985 |
Echinococcus multilocularis | hormone sensitive lipase | 0.0216 | 0.2921 | 0.2807 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0057 | 0.0564 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.003 | 0.0158 | 0.1601 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.002 | 0.0016 | 0.005 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.015 | 0.1938 | 0.5972 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0217 | 0.2934 | 1 |
Onchocerca volvulus | 0.0238 | 0.3248 | 1 | |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0195 | 0.2611 | 0.8837 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0058 | 0.058 | 0.0429 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0249 | 0.0104 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0436 | 0.0436 |
Plasmodium falciparum | glutathione reductase | 0.003 | 0.0158 | 0.1601 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0057 | 0.0564 | 0.1739 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0217 | 0.2934 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0022 | 0.0041 | 0.0127 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0163 | 0.0503 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0163 | 0.0017 |
Plasmodium vivax | hypothetical protein, conserved | 0.0044 | 0.037 | 0.3748 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0086 | 0.0987 | 0.304 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1184 | 0.365 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0184 | 0.0038 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0044 | 0.037 | 0.0215 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0058 | 0.058 | 0.058 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0388 | 0.0234 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0163 | 0.0005 |
Brugia malayi | MH2 domain containing protein | 0.0238 | 0.3245 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0388 | 0.0234 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0058 | 0.058 | 0.5876 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0057 | 0.0564 | 0.1464 |
Plasmodium falciparum | thioredoxin reductase | 0.0086 | 0.0987 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.058 | 0.1786 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0184 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0725 | 0.0725 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0249 | 0.2248 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0388 | 0.0245 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0093 | 0.1102 | 0.0969 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0388 | 0.0388 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0184 | 0.0568 |
Plasmodium falciparum | glutathione reductase | 0.0086 | 0.0987 | 1 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0249 | 0.0093 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0216 | 0.2921 | 0.2921 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0195 | 0.2611 | 0.8837 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0163 | 0.0163 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.0438 | 0.1348 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0093 | 0.1102 | 0.3394 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0403 | 0.0794 |
Onchocerca volvulus | 0.0036 | 0.0249 | 0.0279 | |
Loa Loa (eye worm) | brahma associated protein | 0.0044 | 0.037 | 0.1139 |
Onchocerca volvulus | 0.0044 | 0.037 | 0.0669 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0044 | 0.037 | 1 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0057 | 0.0564 | 0.4305 |
Schistosoma mansoni | kinase | 0.0047 | 0.0421 | 0.0421 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.037 | 0.0686 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.003 | 0.0158 | 0.0011 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1102 | 0.3054 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.3248 | 1 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0436 | 0.1342 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0099 | 0.1184 | 0.1184 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0058 | 0.058 | 0.0439 |
Echinococcus granulosus | tumor protein p63 | 0.0676 | 0.9734 | 0.973 |
Brugia malayi | jmjC domain containing protein | 0.007 | 0.0761 | 0.2345 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.003 | 0.0158 | 0.1601 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.058 | 0.058 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0093 | 0.1102 | 0.3042 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0694 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0044 | 0.037 | 0.1139 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0725 | 0.2235 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0249 | 0.0768 |
Mycobacterium tuberculosis | Probable reductase | 0.0195 | 0.2611 | 0.8837 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0163 | 0.1655 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0184 | 0.0027 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0081 | 0.0917 | 0.0771 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0093 | 0.1102 | 0.5 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.003 | 0.0158 | 0.1434 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0086 | 0.0987 | 0.8781 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0216 | 0.2921 | 0.2921 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0044 | 0.037 | 0.1139 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0195 | 0.2611 | 0.8837 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0195 | 0.2611 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1191 | 0.367 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.0507 | 0.1563 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0057 | 0.0564 | 0.0424 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.1191 | 0.367 |
Plasmodium falciparum | thioredoxin reductase | 0.003 | 0.0158 | 0.1601 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.003 | 0.0158 | 0.1434 |
Plasmodium falciparum | phd finger protein, putative | 0.0058 | 0.058 | 0.5876 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0093 | 0.1102 | 0.3394 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.2819 | 0.8687 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.007 | 0.0761 | 0.0623 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0044 | 0.037 | 0.3748 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0403 | 0.0794 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0057 | 0.0564 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0093 | 0.1102 | 0.0959 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0388 | 0.1196 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.003 | 0.0158 | 0.5 |
Chlamydia trachomatis | SWIB complex protein | 0.0044 | 0.037 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.1102 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.