Detailed information for compound 1609368

Basic information

Technical information
  • TDR Targets ID: 1609368
  • Name: 3-[1-(4-chloro-3-nitrophenyl)ethylideneamino] -1-propan-2-ylthiourea
  • MW: 314.791 | Formula: C12H15ClN4O2S
  • H donors: 2 H acceptors: 2 LogP: 3.08 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(NC(=S)N/N=C(/c1ccc(c(c1)[N+](=O)[O-])Cl)\C)C
  • InChi: 1S/C12H15ClN4O2S/c1-7(2)14-12(20)16-15-8(3)9-4-5-10(13)11(6-9)17(18)19/h4-7H,1-3H3,(H2,14,16,20)/b15-8+
  • InChiKey: HCLBWGSGLMYOFX-OVCLIPMQSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-[1-(4-chloro-3-nitro-phenyl)ethylideneamino]-1-isopropyl-thiourea
  • 3-[1-(4-chloro-3-nitrophenyl)ethylideneamino]-1-isopropylthiourea
  • 3-[1-(4-chloro-3-nitro-phenyl)ethylideneamino]-1-propan-2-yl-thiourea
  • MLS001006656
  • SMR000349645
  • T0515-8527

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi hypothetical protein, conserved 0.0378 0.3425 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0013 0.5
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0378 0.3425 1
Trypanosoma cruzi hypothetical protein, conserved 0.0378 0.3425 1
Leishmania major hypothetical protein, conserved 0.0378 0.3425 1
Brugia malayi PHD-finger family protein 0.003 0.0084 0.0071
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0378 0.3425 0.3416
Schistosoma mansoni hypothetical protein 0.1062 1 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0378 0.3425 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0013 0.5
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0057 0.0043
Echinococcus granulosus Zinc finger RanBP2 type 0.0378 0.3425 0.3416
Schistosoma mansoni RNA binding protein 0.0378 0.3425 0.3416
Leishmania major hypothetical protein, conserved 0.0378 0.3425 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.029 0.029
Echinococcus granulosus zinc finger protein Ran binding 0.0378 0.3425 0.3416
Onchocerca volvulus 0.0378 0.3425 0.222
Loa Loa (eye worm) hypothetical protein 0.0182 0.1549 0.1549
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0378 0.3425 0.3416
Loa Loa (eye worm) hypothetical protein 0.0378 0.3425 0.3425
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0212 0.0199
Brugia malayi YY1-associated factor 2 0.0378 0.3425 0.3416
Echinococcus granulosus SWI:SNF matrix associated 0.1062 1 1
Schistosoma mansoni brg-1 associated factor 0.1062 1 1
Schistosoma mansoni bromodomain containing protein 0.0076 0.0529 0.0517
Brugia malayi Bromodomain containing protein 0.0091 0.0665 0.0653
Loa Loa (eye worm) hypothetical protein 0.0378 0.3425 0.3425
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0378 0.3425 1
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1062 1 1
Echinococcus multilocularis SWI:SNF matrix associated 0.1062 1 1
Schistosoma mansoni fusion 0.0378 0.3425 0.3416
Echinococcus granulosus microtubule associated protein 2 0.0833 0.7803 0.78
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.7803 0.78
Trypanosoma brucei hypothetical protein, conserved 0.0378 0.3425 1
Loa Loa (eye worm) hypothetical protein 0.0378 0.3425 0.3425
Echinococcus granulosus zinc finger protein 0.0024 0.0022 0.0009
Onchocerca volvulus 0.1062 1 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0378 0.3425 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0374 0.0361
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0378 0.3425 0.3416
Brugia malayi SWIB/MDM2 domain containing protein 0.1062 1 1
Schistosoma mansoni hypothetical protein 0.0378 0.3425 0.3416
Schistosoma mansoni hypothetical protein 0.1062 1 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0013 0.5
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0378 0.3425 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0212 0.0199
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0378 0.3425 1
Onchocerca volvulus 0.0378 0.3425 0.222
Loa Loa (eye worm) brahma associated protein 0.1062 1 1
Toxoplasma gondii ran binding protein 0.0378 0.3425 0.3416
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0057 0.0043
Loa Loa (eye worm) hypothetical protein 0.0378 0.3425 0.3425
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.019 0.0177
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1062 1 1
Brugia malayi hypothetical protein 0.0182 0.1549 0.1537
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0374 0.0361
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1062 1 1
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0268 0.0268
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0378 0.3425 0.3416
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0378 0.3425 0.3416
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0013 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0378 0.3425 1
Echinococcus multilocularis zinc finger protein Ran binding 0.0378 0.3425 0.3416
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0378 0.3425 0.3416
Echinococcus multilocularis SWI:SNF matrix associated 0.1062 1 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0616 0.0616
Leishmania major hypothetical protein, conserved 0.0378 0.3425 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0488 0.0475
Trypanosoma brucei hypothetical protein, conserved 0.0378 0.3425 1
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1062 1 1
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.7803 0.78
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0378 0.3425 1
Plasmodium vivax hypothetical protein, conserved 0.1062 1 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0374 0.0374
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1062 1 1
Loa Loa (eye worm) hypothetical protein 0.0378 0.3425 0.3425
Onchocerca volvulus 0.0378 0.3425 0.222
Trichomonas vaginalis conserved hypothetical protein 0.1062 1 1
Chlamydia trachomatis SWIB complex protein 0.1062 1 0.5
Schistosoma mansoni hypothetical protein 0.1062 1 1
Brugia malayi Bromodomain containing protein 0.0046 0.0239 0.0227
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0013 0.5
Leishmania major hypothetical protein, conserved 0.0378 0.3425 1
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0378 0.3425 0.3416
Schistosoma mansoni zinc finger protein 0.0024 0.0022 0.0009
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1062 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0374 0.0374
Echinococcus multilocularis ring and YY1 binding protein 0.0378 0.3425 0.3416
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0021
Echinococcus multilocularis zinc finger protein 0.0024 0.0022 0.0009
Echinococcus granulosus ring and YY1 binding protein 0.0378 0.3425 0.3416
Schistosoma mansoni hypothetical protein 0.0041 0.019 0.0177
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0378 0.3425 0.222
Trypanosoma cruzi WLM domain containing protein, putative 0.0378 0.3425 1
Leishmania major hypothetical protein, conserved 0.0378 0.3425 1
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1062 1 1
Onchocerca volvulus 0.0378 0.3425 0.222
Schistosoma mansoni TRABID protein (C64 family) 0.0378 0.3425 0.3416
Loa Loa (eye worm) hypothetical protein 0.0046 0.024 0.024
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0013 0.0013
Schistosoma mansoni zinc finger protein 0.0378 0.3425 0.3416
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1062 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0488 0.0475
Echinococcus multilocularis SWI:SNF matrix associated 0.1062 1 1
Chlamydia trachomatis DNA topoisomerase I 0.1062 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0041 0.019 0.019
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0378 0.3425 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0013 0.5
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0378 0.3425 0.3416
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0378 0.3425 0.3416
Brugia malayi brahma associated protein 60 kDa 0.1062 1 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0057 0.0043

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.631 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 3.5481 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485366, AID485386, AID504448, AID504454, AID504459] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 63.0957 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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