Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2714 | 0.2714 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0119 | 0.1842 | 0.1842 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0152 | 0.2714 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2714 | 0.2714 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0058 | 0.0227 | 0.0227 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0152 | 0.2714 | 0.1595 |
Schistosoma mansoni | fusion | 0.0152 | 0.2714 | 0.2545 |
Loa Loa (eye worm) | glutamate receptor | 0.0119 | 0.1842 | 0.1842 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0146 | 0.257 | 0.143 |
Schistosoma mansoni | hypothetical protein | 0.0427 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0152 | 0.2714 | 0.2714 |
Chlamydia trachomatis | SWIB complex protein | 0.0427 | 1 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0427 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0108 | 0.1546 | 0.1546 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3142 | 0.2983 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3142 | 0.2983 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0152 | 0.2714 | 0.2714 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0152 | 0.2714 | 0.1595 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0152 | 0.2714 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0152 | 0.2714 | 0.1595 |
Schistosoma mansoni | brg-1 associated factor | 0.0427 | 1 | 1 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0427 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2714 | 0.2714 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0427 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0152 | 0.2714 | 0.2545 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0152 | 0.2714 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.257 | 0.257 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0427 | 1 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0427 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.01 | 0.133 | 0.1129 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0152 | 0.2714 | 0.1595 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0427 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0427 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0427 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0135 | 0.2274 | 0.2095 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0152 | 0.2714 | 0.5 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0152 | 0.2714 | 0.1595 |
Schistosoma mansoni | hypothetical protein | 0.0427 | 1 | 1 |
Schistosoma mansoni | RNA binding protein | 0.0152 | 0.2714 | 0.2545 |
Brugia malayi | YY1-associated factor 2 | 0.0152 | 0.2714 | 0.2714 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 0.2714 | 0.2545 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0152 | 0.2714 | 0.5 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0427 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0168 | 0.3142 | 0.2089 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0152 | 0.2714 | 0.2714 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0152 | 0.2714 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0427 | 1 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0427 | 1 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0152 | 0.2714 | 0.1595 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0152 | 0.2714 | 0.5 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0427 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0427 | 1 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0427 | 1 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0427 | 1 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0152 | 0.2714 | 0.5 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0146 | 0.257 | 0.143 |
Echinococcus multilocularis | geminin | 0.0168 | 0.3142 | 0.2089 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0152 | 0.2714 | 0.1595 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0427 | 1 | 0.5 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0152 | 0.2714 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0152 | 0.2714 | 0.2714 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2714 | 0.2714 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0152 | 0.2714 | 0.2545 |
Onchocerca volvulus | 0.0427 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2714 | 0.2714 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0152 | 0.2714 | 0.1595 |
Plasmodium vivax | hypothetical protein, conserved | 0.0427 | 1 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0427 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0427 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0152 | 0.2714 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.