Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0318 | 0.952 | 1 |
Brugia malayi | tRNA modification GTPase TrmE family protein | 0.0019 | 0.014 | 0.0021 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0019 | 0.014 | 0.0016 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0192 | 0.5558 | 0.5558 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0019 | 0.014 | 0.0147 |
Echinococcus granulosus | rho guanine nucleotide exchange factor 7 | 0.0019 | 0.0125 | 0.0125 |
Brugia malayi | Myosin tail family protein | 0.0019 | 0.0125 | 0.0005 |
Schistosoma mansoni | GTPase activating protein | 0.0019 | 0.014 | 0.0016 |
Schistosoma mansoni | signal transduction protein lnk-related | 0.0019 | 0.014 | 0.0016 |
Schistosoma mansoni | brg-1 associated factor | 0.0318 | 0.952 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Schistosoma mansoni | tensin-related | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0192 | 0.5558 | 0.5558 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0019 | 0.014 | 0.014 |
Echinococcus granulosus | SHC transforming protein 3 | 0.0019 | 0.014 | 0.014 |
Echinococcus multilocularis | signal transduction protein lnk realted | 0.0019 | 0.014 | 0.014 |
Schistosoma mansoni | tyrosine-protein kinase zap-70 | 0.0019 | 0.014 | 0.0016 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0019 | 0.014 | 0.0147 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0038 | 0.0724 | 0.0637 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Onchocerca volvulus | 0.0025 | 0.0334 | 0.0223 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0113 | 0.3091 | 0.3091 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Echinococcus multilocularis | endophilin A3 | 0.0019 | 0.0125 | 0.0125 |
Schistosoma mansoni | tensin | 0.0019 | 0.014 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus granulosus | slit robo rho gtpase activating protein 1 | 0.0019 | 0.0125 | 0.0125 |
Echinococcus multilocularis | 0.0019 | 0.014 | 0.014 | |
Schistosoma mansoni | tyrosine kinase | 0.0025 | 0.0334 | 0.0223 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0025 | 0.0334 | 0.0334 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0318 | 0.952 | 0.952 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0019 | 0.014 | 0.014 |
Echinococcus granulosus | expressed conserved protein | 0.0019 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0019 | 0.014 | 0.0021 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0038 | 0.0724 | 0.0642 |
Entamoeba histolytica | SH2 domain containing protein | 0.0019 | 0.014 | 0.0035 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0019 | 0.014 | 0.014 |
Entamoeba histolytica | protein kinase, putative | 0.0154 | 0.4375 | 1 |
Echinococcus granulosus | tensin C1 domain containing phosphatase | 0.0019 | 0.014 | 0.014 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0019 | 0.014 | 0.0016 |
Brugia malayi | Src substrate cortactin | 0.0019 | 0.0125 | 0.0005 |
Schistosoma mansoni | tensin-related | 0.0019 | 0.014 | 0.0016 |
Echinococcus granulosus | NCK adaptor protein | 0.0038 | 0.0724 | 0.0724 |
Onchocerca volvulus | 0.0025 | 0.0334 | 0.0223 | |
Schistosoma mansoni | tensin | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0044 | 0.0918 | 0.0918 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0025 | 0.0334 | 0.0334 |
Onchocerca volvulus | 0.0025 | 0.0334 | 0.0223 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0113 | 0.3091 | 1 |
Onchocerca volvulus | 0.0025 | 0.0334 | 0.0223 | |
Chlamydia trachomatis | DNA topoisomerase I | 0.0318 | 0.952 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0154 | 0.4375 | 0.4375 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0318 | 0.952 | 1 |
Echinococcus granulosus | Spectrin alpha actinin | 0.0019 | 0.0125 | 0.0125 |
Brugia malayi | SH2 domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.0019 | 0.014 | 0.014 |
Brugia malayi | RhoGAP domain containing protein | 0.0019 | 0.014 | 0.0021 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0192 | 0.5558 | 0.5558 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0113 | 0.3091 | 1 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0318 | 0.952 | 0.952 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.0019 | 0.014 | 0.014 |
Brugia malayi | protein-tyrosine kinase | 0.0173 | 0.4974 | 0.5164 |
Schistosoma mansoni | vav2 | 0.0019 | 0.014 | 0.0016 |
Brugia malayi | cytokine inducible SH2-containing protein 5 | 0.0019 | 0.014 | 0.0021 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Onchocerca volvulus | 0.0019 | 0.014 | 0.0016 | |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0167 | 0.4779 | 0.4779 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0192 | 0.5558 | 0.5558 |
Loa Loa (eye worm) | cytokine inducible SH2-containing protein 5 | 0.0019 | 0.014 | 0.0147 |
Echinococcus multilocularis | intersectin 2 | 0.0019 | 0.0125 | 0.0125 |
Echinococcus multilocularis | SHC transforming protein 3 | 0.0019 | 0.014 | 0.014 |
Brugia malayi | Tensin | 0.0019 | 0.014 | 0.0021 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Echinococcus granulosus | hematopoietic lineage cell specific protein | 0.0019 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0044 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0192 | 0.5558 | 0.5558 |
Echinococcus granulosus | SH2 motif | 0.0019 | 0.014 | 0.014 |
Brugia malayi | Variant SH3 domain containing protein | 0.0038 | 0.0724 | 0.0642 |
Brugia malayi | Variant SH3 domain containing protein | 0.0038 | 0.0724 | 0.0642 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.1072 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus granulosus | tyrosine kinase | 0.0173 | 0.4974 | 0.4974 |
Brugia malayi | Fes/CIP4 homology domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0167 | 0.4779 | 0.4779 |
Schistosoma mansoni | tensin | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | nostrin | 0.0019 | 0.0125 | 0.0125 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0192 | 0.5558 | 0.5558 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0192 | 0.5558 | 0.5558 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0334 | 0.0351 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0318 | 0.952 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.014 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Echinococcus granulosus | arf GAP with SH3 domain ANK repeat and PH | 0.0019 | 0.0125 | 0.0125 |
Onchocerca volvulus | 0.0019 | 0.014 | 0.0016 | |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus granulosus | endophilin A3 | 0.0019 | 0.0125 | 0.0125 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0318 | 0.952 | 0.952 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0025 | 0.0319 | 0.0207 |
Loa Loa (eye worm) | brahma associated protein | 0.0318 | 0.952 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0173 | 0.4974 | 0.4974 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus granulosus | suppressor of cytokine signaling 7 | 0.0019 | 0.014 | 0.014 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Loa Loa (eye worm) | TK protein kinase | 0.0173 | 0.4974 | 0.5225 |
Echinococcus multilocularis | arf GAP with SH3 domain, ANK repeat and PH | 0.0019 | 0.0125 | 0.0125 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0025 | 0.0334 | 0.0334 |
Echinococcus multilocularis | fch and double sh3 domains protein 2 | 0.0019 | 0.0125 | 0.0125 |
Brugia malayi | SRC-1 | 0.0192 | 0.5558 | 0.5785 |
Brugia malayi | brahma associated protein 60 kDa | 0.0318 | 0.952 | 1 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0154 | 0.4375 | 0.4375 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3091 | 0.3246 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Onchocerca volvulus | 0.0113 | 0.3091 | 0.3157 | |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0113 | 0.3091 | 1 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0038 | 0.0724 | 0.0724 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus multilocularis | SH2 domain containing protein 7 | 0.0019 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0019 | 0.014 | 0.0016 | |
Schistosoma mansoni | tyrosine kinase | 0.0192 | 0.5558 | 0.5783 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus multilocularis | SH2 motif | 0.0019 | 0.014 | 0.014 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.3091 | 0.3157 |
Echinococcus multilocularis | breast cancer anti estrogen resistance protein | 0.0019 | 0.0125 | 0.0125 |
Echinococcus multilocularis | rho guanine nucleotide exchange factor 7 | 0.0019 | 0.0125 | 0.0125 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0192 | 0.5558 | 0.5558 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0019 | 0.014 | 0.0147 |
Schistosoma mansoni | nck2/grb4 | 0.0038 | 0.0724 | 0.0637 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0318 | 0.952 | 0.952 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0019 | 0.014 | 0.0021 |
Onchocerca volvulus | Suppressor of cytokine signaling at 36E homolog | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | expressed protein | 0.0019 | 0.0125 | 0.0125 |
Brugia malayi | Protein kinase domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0192 | 0.5558 | 0.5558 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0173 | 0.4974 | 0.4974 |
Onchocerca volvulus | Suppressor of cytokine signaling 7 homolog | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0044 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0038 | 0.0724 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Brugia malayi | Protein kinase domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Schistosoma mansoni | RNA binding protein | 0.0113 | 0.3091 | 0.3157 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Onchocerca volvulus | 0.0049 | 0.1072 | 0.1008 | |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0113 | 0.3091 | 0.316 |
Echinococcus granulosus | breast cancer anti estrogen resistance protein | 0.0019 | 0.0125 | 0.0125 |
Onchocerca volvulus | 0.0025 | 0.0334 | 0.0223 | |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0025 | 0.0334 | 0.0334 |
Echinococcus granulosus | N chimaerin | 0.0019 | 0.014 | 0.014 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0334 | 0.0228 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0113 | 0.3091 | 0.316 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0192 | 0.5558 | 0.5558 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Schistosoma mansoni | SH2A | 0.0019 | 0.014 | 0.0016 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0025 | 0.0334 | 0.0334 |
Schistosoma mansoni | tyrosine kinase | 0.0025 | 0.0334 | 0.0223 |
Echinococcus granulosus | nostrin | 0.0019 | 0.0125 | 0.0125 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0113 | 0.3091 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0318 | 0.952 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Onchocerca volvulus | 0.0025 | 0.0334 | 0.0223 | |
Loa Loa (eye worm) | guanylate kinase | 0.0019 | 0.0125 | 0.0131 |
Echinococcus granulosus | intersectin 2 | 0.0019 | 0.0125 | 0.0125 |
Echinococcus granulosus | suppressor of cytokine signaling 6 | 0.0019 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Echinococcus granulosus | SH2 domain containing protein 7 | 0.0019 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0019 | 0.014 | 0.0016 | |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0113 | 0.3091 | 0.3157 |
Echinococcus multilocularis | slit robo rho gtpase activating protein 1 | 0.0019 | 0.0125 | 0.0125 |
Schistosoma mansoni | fusion | 0.0113 | 0.3091 | 0.3157 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3091 | 0.3246 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0019 | 0.014 | 0.014 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0019 | 0.014 | 0.0035 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3091 | 0.3246 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0113 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | protein-tyrosine kinase | 0.0019 | 0.0125 | 0.0131 |
Brugia malayi | brahma associated protein 60 kDa | 0.0318 | 0.952 | 1 |
Onchocerca volvulus | 0.0113 | 0.3091 | 0.3157 | |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0192 | 0.5558 | 0.5558 |
Loa Loa (eye worm) | STAT protein | 0.0019 | 0.014 | 0.0147 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Loa Loa (eye worm) | p53BP2 | 0.0019 | 0.0125 | 0.0131 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0192 | 0.5558 | 0.5558 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0025 | 0.0334 | 0.0493 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0044 | 0.0918 | 0.0845 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0318 | 0.952 | 1 |
Echinococcus multilocularis | tensin | 0.0019 | 0.014 | 0.014 |
Brugia malayi | Peripheral plasma membrane protein CASK | 0.0019 | 0.0125 | 0.0005 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0113 | 0.3091 | 0.3091 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0113 | 0.3091 | 0.316 |
Loa Loa (eye worm) | TK protein kinase | 0.0154 | 0.4375 | 0.4596 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0113 | 0.3091 | 0.3091 |
Echinococcus granulosus | c src tyrosine kinase | 0.0044 | 0.0918 | 0.0918 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0318 | 0.952 | 0.952 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0318 | 0.952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Schistosoma mansoni | adapter molecule crk | 0.0038 | 0.0724 | 0.0637 |
Echinococcus multilocularis | hematopoietic lineage cell specific protein | 0.0019 | 0.0125 | 0.0125 |
Brugia malayi | Protein kinase domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0044 | 0.0918 | 0.0845 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3091 | 0.3246 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0025 | 0.0334 | 0.0334 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0724 | 0.076 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0113 | 0.3091 | 0.3091 |
Chlamydia trachomatis | SWIB complex protein | 0.0318 | 0.952 | 0.5 |
Loa Loa (eye worm) | thyroid receptor interactor | 0.0019 | 0.0125 | 0.0131 |
Onchocerca volvulus | 0.0019 | 0.014 | 0.0016 | |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0019 | 0.0125 | 0.0131 |
Echinococcus granulosus | SH2 domain containing adapter protein F | 0.0019 | 0.014 | 0.014 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0173 | 0.4974 | 0.4974 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0044 | 0.0918 | 0.0849 |
Brugia malayi | Guanylate kinase family protein | 0.0019 | 0.0125 | 0.0005 |
Echinococcus multilocularis | NCK adaptor protein | 0.0038 | 0.0724 | 0.0724 |
Echinococcus multilocularis | tensin | 0.0019 | 0.014 | 0.014 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0038 | 0.0724 | 0.0724 |
Schistosoma mansoni | zinc finger protein | 0.0113 | 0.3091 | 0.3157 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0019 | 0.014 | 0.014 |
Echinococcus granulosus | tensin | 0.0019 | 0.014 | 0.014 |
Brugia malayi | SH2 domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0019 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Schistosoma mansoni | tyrosine kinase | 0.0044 | 0.0918 | 0.0845 |
Schistosoma mansoni | hypothetical protein | 0.0318 | 0.952 | 1 |
Echinococcus granulosus | src region | 0.0019 | 0.0125 | 0.0125 |
Onchocerca volvulus | 0.0113 | 0.3091 | 0.3157 | |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0113 | 0.3091 | 0.3091 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Schistosoma mansoni | shc transforming protein | 0.0019 | 0.014 | 0.0016 |
Echinococcus granulosus | signal transduction protein lnk realted | 0.0019 | 0.014 | 0.014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0318 | 0.952 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0113 | 0.3091 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor kinase | 0.0019 | 0.0125 | 0.0125 |
Plasmodium vivax | hypothetical protein, conserved | 0.0318 | 0.952 | 0.5 |
Echinococcus granulosus | tyrosine kinase | 0.0025 | 0.0334 | 0.0334 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0192 | 0.5558 | 0.5558 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0113 | 0.3091 | 0.3157 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0113 | 0.3091 | 0.3091 |
Echinococcus granulosus | hypothetical protein | 0.0019 | 0.014 | 0.014 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0318 | 0.952 | 0.952 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0192 | 0.5558 | 0.5558 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0025 | 0.0334 | 0.0334 |
Echinococcus granulosus | SH2 motif | 0.0019 | 0.014 | 0.014 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0038 | 0.0724 | 0.0637 |
Brugia malayi | SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Echinococcus multilocularis | N chimaerin | 0.0019 | 0.014 | 0.014 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0019 | 0.014 | 0.0147 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus multilocularis | tyrosine kinase | 0.0025 | 0.0334 | 0.0334 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0113 | 0.3091 | 0.316 |
Loa Loa (eye worm) | protein kinase C and casein kinase substrate in neurons protein 2 | 0.0019 | 0.0125 | 0.0131 |
Brugia malayi | protein-tyrosine kinase | 0.0019 | 0.0125 | 0.0005 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.0125 | 0.0005 |
Echinococcus granulosus | fch and double sh3 domains protein 2 | 0.0019 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | SRC-1 | 0.0192 | 0.5558 | 0.5838 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0192 | 0.5558 | 0.5558 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0113 | 0.3091 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0113 | 0.3091 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0318 | 0.952 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0044 | 0.0918 | 0.0918 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0192 | 0.5558 | 0.5558 |
Brugia malayi | Protein kinase domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Brugia malayi | YY1-associated factor 2 | 0.0113 | 0.3091 | 0.316 |
Echinococcus multilocularis | suppressor of cytokine signaling 6 | 0.0019 | 0.014 | 0.014 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | SH2 domain containing adapter protein F | 0.0019 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Brugia malayi | SH2 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Echinococcus granulosus | expressed protein | 0.0019 | 0.0125 | 0.0125 |
Onchocerca volvulus | 0.0019 | 0.014 | 0.0016 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.014 | 0.0016 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0025 | 0.0334 | 0.0351 |
Brugia malayi | Variant SH3 domain containing protein | 0.0019 | 0.014 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.014 | 0.0016 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0113 | 0.3091 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0019 | 0.014 | 0.0035 |
Echinococcus multilocularis | SH2 motif | 0.0019 | 0.014 | 0.014 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0173 | 0.4974 | 0.4974 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0019 | 0.014 | 0.014 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0019 | 0.014 | 0.0016 |
Onchocerca volvulus | 0.0318 | 0.952 | 1 | |
Brugia malayi | Protein kinase domain containing protein | 0.0025 | 0.0334 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Echinococcus multilocularis | SH2 motif | 0.0019 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0113 | 0.3091 | 0.3157 | |
Schistosoma mansoni | tyrosine kinase | 0.0192 | 0.5558 | 0.5783 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0113 | 0.3091 | 0.3091 |
Brugia malayi | Spectrin alpha chain | 0.0019 | 0.0125 | 0.0005 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0318 | 0.952 | 1 |
Echinococcus granulosus | epidermal growth factor receptor kinase | 0.0019 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0125 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.014 | 0.0147 |
Schistosoma mansoni | hypothetical protein | 0.0318 | 0.952 | 1 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0038 | 0.0724 | 0.076 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0018 | 0.012 | 0.0126 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0019 | 0.014 | 0.0016 |
Echinococcus multilocularis | transfer RNA-Ala | 0.0019 | 0.0125 | 0.0125 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0019 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3091 | 0.3246 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0019 | 0.014 | 0.0147 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0113 | 0.3091 | 1 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0038 | 0.0724 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1072 | 0.1126 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0173 | 0.4974 | 0.4974 |
Echinococcus multilocularis | Spectrin alpha actinin | 0.0019 | 0.0125 | 0.0125 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0192 | 0.5558 | 0.5558 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.3091 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Anticonvulsant activity in CF1 mouse assessed as protection against maximal electroshock-induced seizure at 300 mg/kg, ip after 30 mins to 4 hrs | ChEMBL. | 22417639 | |
Activity (ADMET) | Neurotoxicity in CF1 mouse at 100 mg/kg, ip after 30 mins by rotarod test | ChEMBL. | 22417639 | |
Activity (ADMET) | Neurotoxicity in CF1 mouse at 300 mg/kg, ip after 30 mins to 4 hrs by rotarod test | ChEMBL. | 22417639 | |
Activity (functional) | Anticonvulsant activity in CF1 mouse assessed as protection against maximal electroshock-induced seizure at 100 mg/kg, ip after 30 mins | ChEMBL. | 22417639 | |
Activity (functional) | Anticonvulsant activity in CF1 mouse assessed as protection against subcutaneous pentylenetetrazole-induced seizure at 300 mg/kg, ip after 30 mins | ChEMBL. | 22417639 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.