Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0082 | 0.0428 | 0.0428 |
Leishmania major | heat shock protein, putative | 0.0124 | 0.1052 | 0.2588 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0261 | 0.3061 | 0.3061 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0124 | 0.1052 | 0.2588 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0241 | 0.2772 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0303 | 0.3678 | 1 |
Echinococcus granulosus | endoplasmin | 0.0241 | 0.2772 | 0.2772 |
Brugia malayi | Hsp90 protein | 0.0124 | 0.1052 | 0.1052 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0734 | 1 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0734 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0734 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0199 | 0.2147 | 0.2147 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0104 | 0.0753 | 0.0753 |
Echinococcus multilocularis | geminin | 0.0199 | 0.2147 | 0.2147 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0135 | 0.0135 |
Brugia malayi | Endoplasmin precursor | 0.0303 | 0.3678 | 0.3678 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0135 | 0.0135 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0241 | 0.2772 | 1 |
Schistosoma mansoni | fusion | 0.0261 | 0.3061 | 0.3061 |
Onchocerca volvulus | 0.0261 | 0.3061 | 0.2965 | |
Schistosoma mansoni | hypothetical protein | 0.0199 | 0.2147 | 0.2147 |
Brugia malayi | MH2 domain containing protein | 0.0271 | 0.3206 | 0.3206 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Onchocerca volvulus | 0.0261 | 0.3061 | 0.2965 | |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.0894 | 0.0894 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0303 | 0.3678 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0082 | 0.0428 | 0.0428 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0734 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0428 | 0.0825 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0062 | 0.0135 | 0.0135 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Echinococcus granulosus | geminin | 0.0199 | 0.2147 | 0.2147 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0261 | 0.3061 | 0.3061 |
Plasmodium vivax | endoplasmin, putative | 0.0303 | 0.3678 | 0.3591 |
Giardia lamblia | Grp94/Hsp90 | 0.0241 | 0.2772 | 0.7443 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0062 | 0.0135 | 0.0135 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0241 | 0.2772 | 0.7443 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0261 | 0.3061 | 0.3061 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0303 | 0.3678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3061 | 0.3061 |
Trichomonas vaginalis | heat shock protein, putative | 0.0303 | 0.3678 | 0.3591 |
Trichomonas vaginalis | heat shock protein, putative | 0.0241 | 0.2772 | 0.2673 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0124 | 0.1052 | 0.0929 |
Schistosoma mansoni | hypothetical protein | 0.0734 | 1 | 1 |
Schistosoma mansoni | heat shock protein | 0.0303 | 0.3678 | 0.3678 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0062 | 0.0135 | 0.0135 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0062 | 0.0135 | 0.0135 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0104 | 0.0753 | 0.0753 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0062 | 0.0135 | 0.0135 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0734 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0241 | 0.2772 | 0.2673 |
Chlamydia trachomatis | SWIB complex protein | 0.0734 | 1 | 1 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0241 | 0.2772 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0124 | 0.1052 | 0.0929 |
Trichomonas vaginalis | heat shock protein, putative | 0.0186 | 0.1958 | 0.1848 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0303 | 0.3678 | 0.3591 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0104 | 0.0753 | 0.0753 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0428 | 0.0428 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Brugia malayi | Probable DNA topoisomerase II | 0.0062 | 0.0135 | 0.0135 |
Schistosoma mansoni | endoplasmin | 0.0303 | 0.3678 | 0.3678 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0271 | 0.3206 | 0.3206 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0261 | 0.3061 | 0.8257 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0261 | 0.3061 | 0.3061 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0261 | 0.3061 | 0.3061 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0303 | 0.3678 | 1 |
Brugia malayi | heat shock protein 90 | 0.0303 | 0.3678 | 0.3678 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0261 | 0.3061 | 0.8257 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3061 | 0.3061 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0303 | 0.3678 | 1 |
Schistosoma mansoni | brg-1 associated factor | 0.0734 | 1 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0303 | 0.3678 | 0.3591 |
Echinococcus multilocularis | heat shock protein | 0.0303 | 0.3678 | 0.3678 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0104 | 0.0753 | 0.0753 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0428 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0135 | 0.0135 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0303 | 0.3678 | 0.3678 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0062 | 0.0135 | 0.0135 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0734 | 1 | 1 |
Brugia malayi | kinase, mitochondrial precursor | 0.0062 | 0.0135 | 0.0135 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0261 | 0.3061 | 0.3061 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0104 | 0.0753 | 0.0753 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0303 | 0.3678 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0734 | 1 | 1 |
Plasmodium vivax | heat shock protein, putative | 0.0124 | 0.1052 | 0.0929 |
Schistosoma mansoni | endoplasmin | 0.0303 | 0.3678 | 0.3678 |
Loa Loa (eye worm) | endoplasmin | 0.0303 | 0.3678 | 0.3678 |
Schistosoma mansoni | zinc finger protein | 0.0261 | 0.3061 | 0.3061 |
Trichomonas vaginalis | heat shock protein, putative | 0.0241 | 0.2772 | 0.2673 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0124 | 0.1052 | 0.1052 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0261 | 0.3061 | 0.3061 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0261 | 0.3061 | 0.3061 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0124 | 0.1052 | 0.2588 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0261 | 0.3061 | 0.8257 |
Treponema pallidum | heat shock protein 90 | 0.0241 | 0.2772 | 1 |
Plasmodium vivax | heat shock protein 90, putative | 0.0124 | 0.1052 | 0.0929 |
Brugia malayi | brahma associated protein 60 kDa | 0.0734 | 1 | 1 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0124 | 0.1052 | 0.0929 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0124 | 0.1052 | 0.0929 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0303 | 0.3678 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0241 | 0.2772 | 0.7443 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0124 | 0.1052 | 0.0929 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0261 | 0.3061 | 0.2965 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3061 | 0.3061 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0261 | 0.3061 | 0.8257 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0303 | 0.3678 | 1 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0124 | 0.1052 | 0.1052 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0166 | 0.1665 | 0.1665 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0261 | 0.3061 | 0.3061 |
Toxoplasma gondii | ran binding protein | 0.0261 | 0.3061 | 0.2965 |
Trypanosoma cruzi | heat shock protein, putative | 0.0124 | 0.1052 | 0.2588 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0734 | 1 | 1 |
Schistosoma mansoni | RNA binding protein | 0.0261 | 0.3061 | 0.3061 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0261 | 0.3061 | 0.2965 |
Onchocerca volvulus | 0.0734 | 1 | 1 | |
Brugia malayi | hypothetical protein | 0.0082 | 0.0428 | 0.0428 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0734 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0261 | 0.3061 | 0.3061 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0124 | 0.1052 | 0.1052 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0166 | 0.1665 | 0.1665 |
Plasmodium vivax | hypothetical protein, conserved | 0.0734 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0104 | 0.0753 | 0.0753 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0062 | 0.0135 | 0.0135 |
Echinococcus granulosus | heat shock protein 90 | 0.0303 | 0.3678 | 0.3678 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0124 | 0.1052 | 0.0929 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0734 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0734 | 1 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0261 | 0.3061 | 0.3061 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0166 | 0.1665 | 0.1665 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0062 | 0.0135 | 0.0135 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0734 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0894 | 0.0894 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0113 | 0.0894 | 0.0894 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0303 | 0.3678 | 1 |
Plasmodium falciparum | endoplasmin, putative | 0.0186 | 0.1958 | 0.1848 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Echinococcus granulosus | heat shock protein | 0.0303 | 0.3678 | 0.3678 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0303 | 0.3678 | 1 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0303 | 0.3678 | 0.3591 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0261 | 0.3061 | 0.8257 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0261 | 0.3061 | 0.8257 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0271 | 0.3206 | 0.3206 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0428 | 0.0825 |
Trypanosoma brucei | heat shock protein, putative | 0.0303 | 0.3678 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0734 | 1 | 1 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0241 | 0.2772 | 0.7443 |
Loa Loa (eye worm) | brahma associated protein | 0.0734 | 1 | 1 |
Onchocerca volvulus | 0.0261 | 0.3061 | 0.2965 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0104 | 0.0753 | 0.0753 |
Plasmodium vivax | heat shock protein 86, putative | 0.0303 | 0.3678 | 0.3591 |
Schistosoma mansoni | DNA topoisomerase II | 0.0062 | 0.0135 | 0.0135 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0062 | 0.0135 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3061 | 0.3061 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0261 | 0.3061 | 0.3061 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0428 | 0.0825 |
Echinococcus granulosus | heat shock protein 90 | 0.0241 | 0.2772 | 0.2772 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0261 | 0.3061 | 0.8257 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0241 | 0.2772 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0303 | 0.3678 | 0.3678 |
Brugia malayi | YY1-associated factor 2 | 0.0261 | 0.3061 | 0.3061 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1665 | 0.1665 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0241 | 0.2772 | 0.7443 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0241 | 0.2772 | 0.2772 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0261 | 0.3061 | 0.8257 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0261 | 0.3061 | 0.8257 |
Trichomonas vaginalis | endoplasmin, putative | 0.0186 | 0.1958 | 0.1848 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0241 | 0.2772 | 0.2772 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0261 | 0.3061 | 0.3061 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0261 | 0.3061 | 0.2965 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0104 | 0.0753 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3061 | 0.3061 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0082 | 0.0428 | 0.0428 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.3061 | 0.8257 |
Schistosoma mansoni | heat shock protein | 0.0303 | 0.3678 | 0.3678 |
Schistosoma mansoni | hypothetical protein | 0.0734 | 1 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0303 | 0.3678 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0734 | 1 | 1 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0261 | 0.3061 | 0.3061 |
Schistosoma mansoni | heat shock protein | 0.0124 | 0.1052 | 0.1052 |
Leishmania major | heat shock protein 83-1 | 0.0303 | 0.3678 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0734 | 1 | 1 |
Echinococcus multilocularis | endoplasmin | 0.0241 | 0.2772 | 0.2772 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0179 | 0.1855 | 0.4855 |
Onchocerca volvulus | 0.0261 | 0.3061 | 0.2965 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0104 | 0.0753 | 0.0753 |
Schistosoma mansoni | hypothetical protein | 0.0734 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.