Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0023 | 0.0435 | 0.0426 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.012 | 0.3388 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Schistosoma mansoni | brg-1 associated factor | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.1004 | 0.0954 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0134 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.3388 | 0.3352 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0839 | 0.0831 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.1004 | 0.0954 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0196 | 0.5713 | 0.5713 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0042 | 0.1027 | 0.2665 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0012 | 0.0108 | 0.0054 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.017 | 0.0161 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0575 | 0.0566 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0028 | 0.0594 | 0.0543 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.1556 | 0.151 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.3388 | 0.3352 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0027 | 0.0563 | 0.0511 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0028 | 0.0594 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Schistosoma mansoni | RNA binding protein | 0.012 | 0.3388 | 0.3352 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.002 | 0.0347 | 0.0552 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.05 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.071 | 0.071 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0188 | 0.0134 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0434 | 0.0425 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.071 | 0.066 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.017 | 0.0161 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 1 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0023 | 0.0425 | 0.0373 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.012 | 0.3388 | 1 |
Onchocerca volvulus | 0.012 | 0.3388 | 0.3352 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0337 | 1 | 1 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0012 | 0.0108 | 0.0054 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.012 | 0.3388 | 0.3352 |
Brugia malayi | TAR-binding protein | 0.006 | 0.1556 | 0.151 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Cation transporter family protein | 0.0023 | 0.0425 | 0.0373 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0012 | 0.0108 | 0.0054 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0425 | 0.0373 |
Echinococcus granulosus | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Brugia malayi | RNA binding protein | 0.006 | 0.1556 | 0.151 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | glutaminase | 0.0256 | 0.7546 | 0.7546 |
Onchocerca volvulus | 0.012 | 0.3388 | 0.3352 | |
Schistosoma mansoni | hypothetical protein | 0.012 | 0.3388 | 0.3352 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.012 | 0.3388 | 0.3352 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0031 | 0.0697 | 0.0688 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3388 | 0.3388 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0012 | 0.0108 | 0.0054 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0023 | 0.0425 | 0.0373 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0023 | 0.0425 | 0.0373 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0034 | 0.0764 | 0.1848 |
Brugia malayi | brahma associated protein 60 kDa | 0.0337 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.012 | 0.3388 | 0.3352 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0508 | 0.05 |
Onchocerca volvulus | 0.0337 | 1 | 1 | |
Schistosoma mansoni | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Brugia malayi | Pre-SET motif family protein | 0.0028 | 0.0594 | 0.0543 |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Loa Loa (eye worm) | TAR-binding protein | 0.006 | 0.1556 | 0.1556 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3388 | 0.3388 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.001 | 0.0054 | 0.0054 |
Onchocerca volvulus | 0.012 | 0.3388 | 0.3352 | |
Chlamydia trachomatis | SWIB complex protein | 0.0337 | 1 | 0.5 |
Trichomonas vaginalis | glutaminase, putative | 0.0256 | 0.7546 | 0.7543 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0023 | 0.0425 | 0.0373 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0042 | 0.1027 | 0.2665 |
Echinococcus multilocularis | peregrin | 0.0092 | 0.2547 | 0.2506 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0023 | 0.0435 | 0.0382 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Onchocerca volvulus | 0.0223 | 0.6539 | 0.652 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0425 | 0.0373 |
Onchocerca volvulus | 0.012 | 0.3388 | 0.3352 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0028 | 0.0594 | 0.0543 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0042 | 0.1027 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0188 | 0.0134 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0042 | 0.1027 | 0.2665 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0188 | 0.0134 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0763 | 0.0755 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0028 | 0.0594 | 0.0543 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0763 | 0.0755 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0434 | 0.0425 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0763 | 0.0755 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 1 | 1 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.012 | 0.3388 | 0.3352 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0337 | 1 | 1 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0084 | 0.2297 | 0.2255 |
Plasmodium vivax | SET domain protein, putative | 0.0028 | 0.0594 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0435 | 0.0435 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0023 | 0.0425 | 0.0373 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.012 | 0.3388 | 0.3382 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0337 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.006 | 0.1556 | 0.151 |
Schistosoma mansoni | fusion | 0.012 | 0.3388 | 0.3352 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0134 |
Onchocerca volvulus | 0.0023 | 0.0425 | 0.0373 | |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0009 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | zinc finger protein | 0.012 | 0.3388 | 0.3352 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.3388 | 0.3352 |
Echinococcus multilocularis | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | Cation transporter family protein | 0.0023 | 0.0425 | 0.0373 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0012 | 0.0108 | 0.0054 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0042 | 0.1027 | 0.0978 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3388 | 0.3388 |
Schistosoma mansoni | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0042 | 0.1027 | 0.1019 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0425 | 0.0373 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.012 | 0.3388 | 0.3352 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0042 | 0.1027 | 0.0978 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.1004 | 0.0954 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.001 | 0.0054 | 0.0054 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.012 | 0.3388 | 0.3087 |
Onchocerca volvulus | 0.0023 | 0.0425 | 0.0373 | |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.1556 | 0.151 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0337 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | LGC-31 protein | 0.0023 | 0.0425 | 0.0425 |
Echinococcus granulosus | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Pre-SET motif family protein | 0.0196 | 0.5713 | 0.569 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0425 | 0.0373 |
Onchocerca volvulus | 0.0023 | 0.0425 | 0.0373 | |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0337 | 1 | 1 |
Echinococcus multilocularis | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0603 | 0.0594 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0188 | 0.0134 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.012 | 0.3388 | 0.3352 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Onchocerca volvulus | Alhambra homolog | 0.0023 | 0.0435 | 0.0382 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0014 | 0.017 | 0.0116 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0023 | 0.0425 | 0.0425 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0425 | 0.0373 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0042 | 0.1027 | 0.2665 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1173 | 0.1173 |
Echinococcus granulosus | nAChR subunit | 0.0012 | 0.0108 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0028 | 0.0594 | 0.0543 |
Brugia malayi | Bromodomain containing protein | 0.0086 | 0.2365 | 0.2323 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Onchocerca volvulus | 0.0012 | 0.0108 | 0.0054 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0433 | 0.0424 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0015 | 0.0207 | 0.0153 |
Brugia malayi | PHD-finger family protein | 0.0023 | 0.0435 | 0.0382 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0028 | 0.0594 | 0.0543 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0508 | 0.05 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0023 | 0.0425 | 0.0373 |
Echinococcus granulosus | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0337 | 1 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0023 | 0.0425 | 0.0373 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.1004 | 0.0954 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0188 | 0.0134 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Echinococcus granulosus | tar DNA binding protein | 0.006 | 0.1556 | 0.151 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0188 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0083 | 0.0074 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0023 | 0.0435 | 0.0382 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.012 | 0.3388 | 1 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0023 | 0.0425 | 0.0425 |
Echinococcus multilocularis | nAChR subunit | 0.0012 | 0.0108 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.017 | 0.0161 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.05 | 0.0492 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.006 | 0.1556 | 0.1556 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.012 | 0.3388 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | glutaminase | 0.0256 | 0.7546 | 0.7532 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0207 | 0.0207 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0337 | 1 | 0.5 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0014 | 0.017 | 0.0116 |
Schistosoma mansoni | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0012 | 0.0108 | 0.0108 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0042 | 0.1027 | 0.1019 |
Loa Loa (eye worm) | ACC-1 protein | 0.0023 | 0.0425 | 0.0425 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.017 | 0.0161 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0012 | 0.0108 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.017 | 0.0161 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0434 | 0.0425 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Toxoplasma gondii | ran binding protein | 0.012 | 0.3388 | 0.3382 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.1004 | 0.0954 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.1004 | 0.0954 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.1556 | 0.151 |
Echinococcus granulosus | ring and YY1 binding protein | 0.012 | 0.3388 | 0.3352 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.012 | 0.3388 | 0.3352 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0425 | 0.0425 |
Onchocerca volvulus | 0.0023 | 0.0425 | 0.0373 | |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0023 | 0.0425 | 0.0373 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0034 | 0.0764 | 0.1848 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0188 | 0.0134 |
Brugia malayi | RNA recognition motif domain containing protein | 0.006 | 0.1556 | 0.151 |
Onchocerca volvulus | 0.0023 | 0.0425 | 0.0373 | |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0014 | 0.017 | 0.017 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0435 | 0.0382 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.1556 | 0.151 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0012 | 0.0108 | 0.0054 |
Trichomonas vaginalis | set domain proteins, putative | 0.0223 | 0.6539 | 0.6535 |
Loa Loa (eye worm) | glutaminase 2 | 0.0256 | 0.7546 | 0.7546 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0433 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3388 | 0.3388 |
Loa Loa (eye worm) | brahma associated protein | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.3388 | 0.3352 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.1004 | 0.0954 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0023 | 0.0425 | 0.0373 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.1173 | 0.1165 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0508 | 0.05 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0207 | 0.0153 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0023 | 0.0425 | 0.0425 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0435 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0763 | 0.0755 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0188 | 0.0188 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0023 | 0.0425 | 0.0373 |
Onchocerca volvulus | 0.0023 | 0.0425 | 0.0373 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0434 | 0.0425 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0697 | 0.0688 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0042 | 0.1004 | 0.0954 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0023 | 0.0425 | 0.0373 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0042 | 0.1027 | 0.1019 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0425 | 0.0373 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.012 | 0.3388 | 1 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0042 | 0.1027 | 0.0978 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Cation transporter family protein | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0023 | 0.0425 | 0.0373 |
Onchocerca volvulus | 0.0028 | 0.0594 | 0.0543 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0433 | 0.0424 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0337 | 1 | 1 |
Giardia lamblia | GTOR | 0.0042 | 0.1027 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0425 | 0.0373 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0047 | 0.1161 | 0.1113 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0134 |
Echinococcus granulosus | peregrin | 0.0092 | 0.2547 | 0.2506 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0014 | 0.017 | 0.0116 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0018 | 0.0273 | 0.0321 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.1556 | 0.151 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0023 | 0.0435 | 0.0426 |
Brugia malayi | YY1-associated factor 2 | 0.012 | 0.3388 | 0.3352 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0337 | 1 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.012 | 0.3388 | 0.3352 |
Loa Loa (eye worm) | ACC-1 protein | 0.0023 | 0.0425 | 0.0425 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.012 | 0.3388 | 0.3352 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0763 | 0.0755 |
Plasmodium vivax | hypothetical protein, conserved | 0.0337 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0188 | 0.0134 |
Brugia malayi | glutaminase DH11.1 | 0.0256 | 0.7546 | 0.7532 |
Mycobacterium ulcerans | glutaminase | 0.0256 | 0.7546 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0047 | 0.1161 | 0.1113 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0023 | 0.0425 | 0.0425 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0042 | 0.1027 | 0.2665 |
Onchocerca volvulus | 0.0012 | 0.0108 | 0.0054 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0032 | 0.071 | 0.066 |
Schistosoma mansoni | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0023 | 0.0425 | 0.0373 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0188 | 0.0134 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0425 | 0.0373 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0188 | 0.0134 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0337 | 1 | 1 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0042 | 0.1027 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0028 | 0.0594 | 0.0543 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.001 | 0.0054 | 0.0054 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0108 | 0.0108 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0023 | 0.0425 | 0.0373 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0023 | 0.0425 | 0.0373 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0047 | 0.1161 | 0.1161 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.012 | 0.3388 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0042 | 0.1004 | 0.1004 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0337 | 1 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0023 | 0.0425 | 0.0373 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0042 | 0.1027 | 0.2665 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0014 | 0.017 | 0.0116 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3388 | 0.3388 |
Loa Loa (eye worm) | RNA binding protein | 0.006 | 0.1556 | 0.1556 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0042 | 0.1027 | 0.0978 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0028 | 0.0594 | 0.0543 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0034 | 0.0764 | 0.1848 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1161 | 0.1161 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0023 | 0.0425 | 0.0373 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.012 | 0.3388 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0042 | 0.1027 | 0.1027 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0015 | 0.0207 | 0.0153 |
Echinococcus multilocularis | enhancer of polycomb | 0.0014 | 0.0163 | 0.0109 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0023 | 0.0425 | 0.0425 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0337 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0425 | 0.0373 |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.3388 | 1 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0023 | 0.0425 | 0.0373 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.965 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.584 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.575 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.493 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.