Detailed information for compound 1634033

Basic information

Technical information
  • TDR Targets ID: 1634033
  • Name: NCI60_002357
  • MW: 295.332 | Formula: C18H17NO3
  • H donors: 1 H acceptors: 1 LogP: 2.19 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCc2c3C1C(O)c1ccccc1c3c1c(c2)OCO1
  • InChi: 1S/C18H17NO3/c1-19-7-6-10-8-13-18(22-9-21-13)15-11-4-2-3-5-12(11)17(20)16(19)14(10)15/h2-5,8,16-17,20H,6-7,9H2,1H3
  • InChiKey: NVMGTUCOAQKLLO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-8-ol
  • MEGxp0_002052

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase Srms 0.0009 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0009 0.0002 0.0001
Brugia malayi hypothetical protein 0.002 0.0044 0.0052
Echinococcus multilocularis 0.0009 0.0002 0.0002
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1096 0.4212 0.5054
Schistosoma mansoni lamin 0.0027 0.0071 0.007
Brugia malayi ecdysteroid receptor 0.001 0.0005 0.0006
Schistosoma mansoni tensin-related 0.0009 0.0002 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.1189 0.4574 0.5466
Onchocerca volvulus 0.0044 0.0135 0.0317
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.007
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0259 0.097 0.0969
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0124
Entamoeba histolytica cysteine protease, putative 0.0259 0.097 0.23
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Plasmodium vivax vivapain-3 0.0607 0.2319 0.2292
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0135 0.0162
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0044 0.0135 0.0161
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0044 0.0135 0.0161
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0135 0.0162
Loa Loa (eye worm) hypothetical protein 0.2159 0.8333 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0059 0.1394
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0044 0.0135 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.046 0.1749 0.2615
Toxoplasma gondii preprocathepsin c precursor, putative 0.2589 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0059 0.1394
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0059 0.5
Brugia malayi hypothetical protein 0.002 0.0044 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0259 0.097 0.1421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.097 0.1421
Echinococcus granulosus glycine receptor subunit alpha 1 0.0044 0.0135 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0044 0.0135 0.0161
Brugia malayi Cell death specification protein 2 0.0009 0.0001 0.0002
Echinococcus granulosus cathepsin b 0.2159 0.8333 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0135 0.0162
Brugia malayi Cathepsin L-like precursor 0.0348 0.1315 0.1578
Onchocerca volvulus 0.0027 0.0071 0.0166
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.002 0.0044 0.0052
Entamoeba histolytica cysteine protease, putative 0.0259 0.097 0.23
Giardia lamblia Cathepsin B precursor 0.0259 0.097 0.0969
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Schistosoma mansoni hypothetical protein 0.0292 0.1096 0.1095
Brugia malayi Sex muscle abnormal protein 5 0.0009 0.0002 0.0002
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0005 0.0006
Echinococcus granulosus NCK adaptor protein 0.0009 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0005 0.0006
Entamoeba histolytica cysteine protease, putative 0.0259 0.097 0.23
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Giardia lamblia Cathepsin B precursor 0.0847 0.3247 0.3246
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Plasmodium falciparum serine repeat antigen 4 0.0259 0.097 0.0938
Echinococcus multilocularis protein dispatched 1 0.0049 0.0155 0.0185
Loa Loa (eye worm) LGC-31 protein 0.0044 0.0135 0.0161
Schistosoma mansoni nuclear hormone receptor 0.001 0.0005 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0005 0.0006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0071 0.0085
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0041 0.0052
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0259 0.097 0.1421
Brugia malayi cytokine inducible SH2-containing protein 5 0.0009 0.0002 0.0002
Echinococcus multilocularis protein patched 0.0043 0.0131 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0259 0.097 0.1421
Toxoplasma gondii cathepsin CPC1 0.2589 1 1
Echinococcus multilocularis dna polymerase kappa 0.002 0.0041 0.0049
Onchocerca volvulus 0.1096 0.4212 1
Echinococcus multilocularis c src tyrosine kinase 0.0009 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0005 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0005 0.0006
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Echinococcus granulosus cathepsin l1 0.0748 0.2863 0.3435
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0259 0.097 0.1164
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis neuropeptide s receptor 0.0471 0.1789 0.2147
Brugia malayi cathepsin F-like cysteine proteinase 0.0348 0.1315 0.1578
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0041 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0607 0.2319 0.5051
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0259 0.097 0.23
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Onchocerca volvulus 0.1096 0.4212 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0044 0.0052
Onchocerca volvulus 0.0044 0.0135 0.0317
Brugia malayi Cation transporter family protein 0.0044 0.0135 0.0162
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0044 0.0135 0.0133
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) SH2 domain-containing protein 0.0009 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0005 0.0006
Brugia malayi hypothetical protein 0.0009 0.0001 0.0002
Giardia lamblia Cathepsin L-like protease 0.0259 0.097 0.0969
Onchocerca volvulus 0.0009 0.0002 0.0001
Schistosoma mansoni suppressor of cytokine signaling 0.0009 0.0002 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0044 0.0052
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0131 0.0157
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0348 0.1315 0.1578
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0748 0.2863 0.4319
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0607 0.2319 0.3487
Brugia malayi hypothetical protein 0.0009 0.0001 0.0002
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0044 0.0135 0.0162
Brugia malayi SRC-1 0.0009 0.0002 0.0002
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0009 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0131 0.0157
Echinococcus granulosus suppressor of cytokine signaling 7 0.0009 0.0002 0.0002
Schistosoma mansoni cathepsin F (C01 family) 0.1096 0.4212 0.4211
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Leishmania major cysteine peptidase A (CPA) 0.1096 0.4212 0.9202
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0009 0.0002 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.097 0.1164
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0005 0.0004
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0009 0.0002 0.0002
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0518 0.0621
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Schistosoma mansoni shc transforming protein 0.0009 0.0002 0.0001
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.0009 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.097 0.1421
Onchocerca volvulus 0.0009 0.0002 0.0001
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Echinococcus multilocularis cysteine protease 0.1096 0.4212 0.5054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0059 0.1583
Brugia malayi cathepsin L precursor 0.0259 0.097 0.1164
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0847 0.3247 0.4908
Brugia malayi Cation transporter family protein 0.0044 0.0135 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Schistosoma mansoni cpg binding protein 0.0029 0.0078 0.0077
Brugia malayi Protein kinase domain containing protein 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0024 0.0057 0.0131
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase shark 0.0009 0.0002 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0044 0.0135 0.0161
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0041 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus multilocularis musashi 0.0027 0.0071 0.0085
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0059 0.1394
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0041 0.058
Leishmania major cathepsin L-like protease 0.1189 0.4574 1
Plasmodium vivax unspecified product 0.0348 0.1315 0.1284
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni patched 1 0.0043 0.0131 0.013
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2159 0.8333 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Trypanosoma cruzi cruzipain precursor, putative 0.0348 0.1315 0.1536
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0059 0.007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Giardia lamblia Cathepsin B precursor 0.0847 0.3247 0.3246
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0259 0.097 0.0969
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.097 0.1421
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.046 0.1749 0.2615
Echinococcus multilocularis tensin 0.0009 0.0002 0.0002
Brugia malayi nuclear receptor NHR-88 0.001 0.0005 0.0006
Echinococcus granulosus SH2 motif 0.0009 0.0002 0.0002
Brugia malayi Cathepsin L-like cysteine proteinase 0.0748 0.2863 0.3435
Echinococcus multilocularis cathepsin b 0.2159 0.8333 1
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Echinococcus multilocularis protocadherin 11 0.0009 0.0001 0.0001
Giardia lamblia Cathepsin B precursor 0.0259 0.097 0.0969
Giardia lamblia Cysteine protease 0.0259 0.097 0.0969
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Echinococcus multilocularis SHC transforming protein 3 0.0009 0.0002 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0259 0.097 0.0969
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0005 0.0006
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.2673 0.3207
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0017 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0059 0.0038
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0002 0.0002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0005 0.0004
Echinococcus multilocularis cathepsin L cysteine protease 0.1096 0.4212 0.5054
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Brugia malayi excitatory GABA receptor EXP-1A 0.0044 0.0135 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0748 0.2863 0.3435
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0009 0.0002 0.0002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0005 0.0006
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0005 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0131 0.0157
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0009 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0005 0.0006
Brugia malayi intermediate filament protein 0.0027 0.0071 0.0086
Loa Loa (eye worm) SH2 domain-containing protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Brugia malayi steroid hormone receptor 0.001 0.0005 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0005 0.0006
Leishmania major cathepsin L-like protease 0.1096 0.4212 0.9202
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0059 0.0136
Loa Loa (eye worm) hypothetical protein 0.0348 0.1315 0.1577
Brugia malayi cathepsin B-like cysteine proteinase 0.2159 0.8333 1
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0009 0.0002 0.0002
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0044 0.0135 0.0161
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0044 0.0135 0.0162
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2159 0.8333 0.8333
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2159 0.8333 0.8333
Loa Loa (eye worm) hypothetical protein 0.0748 0.2863 0.3435
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Leishmania major cathepsin L-like protease 0.1096 0.4212 0.9202
Brugia malayi cathepsin Z-like cysteine proteinase 0.046 0.1749 0.2099
Onchocerca volvulus 0.0009 0.0002 0.0001
Giardia lamblia Cysteine protease 0.0259 0.097 0.0969
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0607 0.2319 0.3487
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0024 0.0057 0.0055
Echinococcus granulosus microtubule associated protein 2 0.0699 0.2673 0.3207
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0044 0.0135 0.0161
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0044 0.0135 0.0162
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.007
Onchocerca volvulus 0.1096 0.4212 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.097 0.1421
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.1096 0.4212 1
Echinococcus multilocularis cathepsin L 0.0607 0.2319 0.2782
Echinococcus granulosus cpg binding protein 0.0031 0.0085 0.0101
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0009 0.0002 0.0001
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0024 0.0057 0.0068
Onchocerca volvulus 0.1096 0.4212 1
Loa Loa (eye worm) SRC-1 0.0009 0.0002 0.0002
Giardia lamblia DINP protein human, muc B family 0.002 0.0041 0.004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0204 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus granulosus cathepsin l1 0.1096 0.4212 0.5054
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0259 0.097 0.1421
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0204 1
Loa Loa (eye worm) hypothetical protein 0.0259 0.097 0.1163
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0259 0.097 0.0938
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0044 0.0135 0.0133
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0607 0.2319 0.2318
Plasmodium vivax serine-repeat antigen (SERA) 0.0259 0.097 0.0938
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0204 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0821 0.3147 0.3776
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus granulosus protocadherin 11 0.0009 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Echinococcus multilocularis protocadherin 11 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0041 0.0052
Echinococcus granulosus tyrosine protein kinase ABL1 0.0009 0.0002 0.0002
Echinococcus granulosus intermediate filament protein 0.0027 0.0071 0.0085
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0009 0.0002 0.0002
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.002 0.0044 0.0052
Leishmania major cathepsin L-like protease 0.1189 0.4574 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0009 0.0002 0.0002
Echinococcus multilocularis SH2 motif 0.0009 0.0002 0.0002
Giardia lamblia Cysteine protease 0.0259 0.097 0.0969
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0005 0.0006
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0009 0.0002 0.0001
Onchocerca volvulus 0.0009 0.0002 0.0001
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.1143 0.4396 0.4376
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2159 0.8333 0.8333
Echinococcus multilocularis tyrosine protein kinase shark 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Schistosoma mansoni nAChR subunit 0.002 0.0044 0.0042
Loa Loa (eye worm) cathepsin B 0.0847 0.3247 0.3896
Echinococcus granulosus tyrosine protein kinase Src42A 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0024 0.0057 0.0131
Plasmodium falciparum cysteine proteinase falcipain 1 0.0607 0.2319 0.2292
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0059 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0059 0.007
Onchocerca volvulus 0.1096 0.4212 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.046 0.1749 0.2615
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.0009 0.0001 0.0001
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0044 0.0135 0.0161
Entamoeba histolytica protein kinase, putative 0.0009 0.0002 0.0001
Onchocerca volvulus 0.002 0.0044 0.01
Echinococcus granulosus cathepsin L cysteine protease 0.0607 0.2319 0.2782
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0059 0.1394
Onchocerca volvulus 0.1096 0.4212 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Trypanosoma cruzi major cysteine proteinase, putative 0.0352 0.1331 0.1556
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Loa Loa (eye worm) ctsf protein 0.1096 0.4212 0.5054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0005 0.0006
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0847 0.3247 0.3246
Brugia malayi Papain family cysteine protease containing protein 0.0607 0.2319 0.2783
Giardia lamblia Cathepsin L precursor 0.0259 0.097 0.0969
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0124
Brugia malayi Cathepsin L-like precursor 0.1096 0.4212 0.5054
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0001 0.0001
Brugia malayi hypothetical protein 0.002 0.0044 0.0052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0135 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Onchocerca volvulus 0.0259 0.097 0.23
Echinococcus granulosus dna polymerase eta 0.002 0.0041 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Onchocerca volvulus 0.0009 0.0002 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Echinococcus granulosus expressed conserved protein 0.0094 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Echinococcus multilocularis dna polymerase eta 0.002 0.0041 0.0049
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0044 0.0135 0.0161
Brugia malayi cathepsin L-like precursor 0.0748 0.2863 0.3435
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0044 0.0135 0.0161
Echinococcus multilocularis X box binding protein 1 0.0292 0.1096 0.1315
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.2319 0.5504
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Leishmania major cathepsin L-like protease 0.1096 0.4212 0.9202
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0009 0.0002 0.0001
Schistosoma mansoni adapter molecule crk 0.0009 0.0002 0.0001
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1096 0.4212 0.4191
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0259 0.097 0.0969
Loa Loa (eye worm) hypothetical protein 0.1096 0.4212 0.5054
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Giardia lamblia Cathepsin L precursor 0.0259 0.097 0.0969
Echinococcus granulosus ccaat enhancer binding protein delta 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0041 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Schistosoma mansoni thyroid hormone receptor 0.001 0.0005 0.0004
Echinococcus multilocularis nAChR subunit 0.0044 0.0135 0.0161
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0009 0.0002 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.1096 0.4212 0.5054
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0009 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0005 0.0006
Brugia malayi nuclear hormone receptor 0.001 0.0005 0.0006
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0259 0.097 0.0938
Leishmania major cathepsin L-like protease 0.1096 0.4212 0.9202
Echinococcus granulosus tyrosine protein kinase Blk 0.0009 0.0002 0.0002
Echinococcus granulosus tyrosine kinase 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0607 0.2319 0.2318
Leishmania major cathepsin L-like protease 0.1189 0.4574 1
Brugia malayi Cathepsin L-like precursor 0.1096 0.4212 0.5054
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.0009 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0005 0.0006
Giardia lamblia Cathepsin L precursor 0.0259 0.097 0.0969
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0002 0.0002
Giardia lamblia Hypothetical protein 0.0259 0.097 0.0969
Plasmodium vivax vivapain-1 0.0607 0.2319 0.2292
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.2589 1 1
Echinococcus granulosus lamin 0.0027 0.0071 0.0085
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0071 0.0085
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0044 0.0135 0.0161
Echinococcus granulosus glycine receptor subunit alpha 1 0.0044 0.0135 0.0161
Toxoplasma gondii cathepsin B 0.0847 0.3247 0.3124
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0259 0.097 0.1163
Onchocerca volvulus 0.002 0.0044 0.01
Brugia malayi RhoGAP domain containing protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Echinococcus granulosus glycine receptor subunit beta 0.0044 0.0135 0.0161
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0002 0.0002
Echinococcus multilocularis nAChR subunit 0.0024 0.0057 0.0068
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni intermediate filament proteins 0.0027 0.0071 0.007
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0044 0.0135 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0748 0.2863 0.4319
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0259 0.097 0.0938
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Giardia lamblia Hypothetical protein 0.0259 0.097 0.0969
Leishmania major cathepsin L-like protease 0.1096 0.4212 0.9202
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0059 0.1394
Brugia malayi Cathepsin L-like precursor 0.1096 0.4212 0.5054
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0059 0.0136
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0005 0.0006
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0044 0.0135 0.0162
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0041 0.0368
Onchocerca volvulus 0.0044 0.0135 0.0317
Schistosoma mansoni cathepsin F (C01 family) 0.1096 0.4212 0.4211
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0044 0.0135 0.0161
Schistosoma mansoni tyrosine kinase 0.0009 0.0002 0.0001
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0057 0.0068
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Schistosoma mansoni growth factor receptor-bound protein 0.0009 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0005 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0607 0.2319 0.5051
Loa Loa (eye worm) hypothetical protein 0.0259 0.097 0.1163
Echinococcus granulosus tyrosine protein kinase Lyn 0.0009 0.0002 0.0002
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0022 0.0027
Brugia malayi cathepsin F-like cysteine proteinase 0.0259 0.097 0.1164
Echinococcus multilocularis neuropeptide receptor A26 0.0471 0.1789 0.2147
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0005 0.0006
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0044 0.0052
Trypanosoma cruzi cruzipain precursor, putative 0.1189 0.4574 0.5466
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0022 0.0026
Plasmodium falciparum serine repeat antigen 7 0.0259 0.097 0.0938
Loa Loa (eye worm) GABA receptor subunit 0.0024 0.0057 0.0068
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0259 0.097 0.0969
Plasmodium vivax vivapain-2 0.1096 0.4212 0.4191
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Src64B 0.0009 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.1189 0.4574 0.5466
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0748 0.2863 0.3435
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0259 0.097 0.0969
Echinococcus granulosus nAChR subunit 0.0024 0.0057 0.0068
Brugia malayi Cation transporter family protein 0.0044 0.0135 0.0162
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1096 0.4212 0.5054
Brugia malayi hypothetical protein 0.002 0.0044 0.0052
Echinococcus granulosus SHC transforming protein 3 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trypanosoma cruzi major cysteine proteinase, putative 0.0259 0.097 0.112
Echinococcus multilocularis lamin dm0 0.0027 0.0071 0.0085
Echinococcus multilocularis cysteine protease 0.1096 0.4212 0.5054
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0002 0.0002
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.2589 1 1
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0352 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0135 0.0162
Loa Loa (eye worm) fibroinase 0.1096 0.4212 0.5054
Schistosoma mansoni hypothetical protein 0.0009 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.007
Entamoeba histolytica hypothetical protein 0.0259 0.097 0.23
Toxoplasma gondii cathepsin CPC2 0.1143 0.4396 0.4294
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0009 0.0002 0.0002
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0044 0.0135 0.0161
Brugia malayi Protein kinase domain containing protein 0.0009 0.0002 0.0002
Plasmodium falciparum serine repeat antigen 3 0.0259 0.097 0.0938
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0259 0.097 0.0938
Brugia malayi Cell death specification protein 2 0.0009 0.0001 0.0002
Schistosoma mansoni cathepsin C 0.0259 0.097 0.0969
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0259 0.097 0.0938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0005 0.0006
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Plasmodium falciparum serine repeat antigen 1 0.0259 0.097 0.0938
Schistosoma mansoni cathepsin B (C01 family) 0.0259 0.097 0.0969
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0009 0.0002 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0005 0.0006
Echinococcus granulosus suppressor of cytokine signaling 6 0.0009 0.0002 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1096 0.4212 1
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0044 0.0042
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0259 0.097 0.23
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0005 0.0006
Echinococcus multilocularis growth factor receptor bound protein 2 0.0009 0.0002 0.0002
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Plasmodium falciparum serine repeat antigen 6 0.0259 0.097 0.0938
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.002 0.0044 0.0052
Plasmodium falciparum serine repeat antigen 8 0.0259 0.097 0.0938
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.002 0.0044 0.0052
Onchocerca volvulus 0.0027 0.0071 0.0166
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0059 0.0136
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0009 0.0002 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0005 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.0607 0.2319 0.2783
Loa Loa (eye worm) ACC-1 protein 0.0044 0.0135 0.0161
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0005 0.0006
Echinococcus granulosus protocadherin 11 0.0009 0.0001 0.0001
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0131 0.0157
Schistosoma mansoni signal transduction protein lnk-related 0.0009 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0005 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Giardia lamblia Cathepsin L precursor 0.0259 0.097 0.0969
Echinococcus granulosus hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni SH2A 0.0009 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase Srms 0.0009 0.0002 0.0002
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0041 0.058
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0044 0.0135 0.0161
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0009 0.0002 0.0002
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0044 0.0135 0.0161
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0259 0.097 0.1421
Echinococcus multilocularis tensin 0.0009 0.0002 0.0002
Toxoplasma gondii cathepsin CPL 0.1096 0.4212 0.4106
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0259 0.097 0.1421
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.2319 0.5504
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0035 0.022
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.002 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.0348 0.1315 0.1577
Giardia lamblia Cathepsin B precursor 0.0847 0.3247 0.3246
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0044 0.0042
Trypanosoma brucei unspecified product 0.002 0.0041 0.0052
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0135 0.0162
Echinococcus granulosus cathepsin L cysteine proteinase 0.1096 0.4212 0.5054
Brugia malayi protein-tyrosine kinase 0.0009 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0352 0.0422
Loa Loa (eye worm) acetylcholine receptor protein 0.002 0.0044 0.0052
Echinococcus granulosus cathepsin b 0.2159 0.8333 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0044 0.0135 0.0162
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0204 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0009 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.0259 0.097 0.1163
Schistosoma mansoni acetylcholine receptor subunit beta 0.002 0.0044 0.0042
Echinococcus granulosus tyrosine kinase 0.0009 0.0002 0.0002
Brugia malayi hypothetical protein 0.002 0.0044 0.0052
Echinococcus multilocularis NCK adaptor protein 0.0009 0.0002 0.0002
Schistosoma mansoni suppressor of cytokine signaling 0.0009 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.1189 0.4574 0.5466
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0204 0.0244
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni tensin 0.0009 0.0002 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0259 0.097 0.0969
Echinococcus granulosus X box binding protein 1 0.0292 0.1096 0.1315
Schistosoma mansoni lamin 0.0027 0.0071 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0009 0.0002 0.0001
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0002 0.0002
Onchocerca volvulus Cathepsin L homolog 0.0259 0.097 0.23
Echinococcus granulosus FTZ F1 alpha 0.001 0.0005 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0607 0.2319 0.2747
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1096 0.4212 0.5054
Onchocerca volvulus 0.0024 0.0059 0.0136
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1096 0.4212 0.5054
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Plasmodium falciparum serine repeat antigen 9 0.0259 0.097 0.0938
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0041 0.005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0009 0.0002 0.0001
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Loa Loa (eye worm) hypothetical protein 0.0748 0.2863 0.3435
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0041 0.0049
Giardia lamblia Cathepsin B precursor 0.0259 0.097 0.0969
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Loa Loa (eye worm) cell death specification protein 2 0.0009 0.0001 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0071 0.0086
Giardia lamblia Cysteine protease 0.0259 0.097 0.0969
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0002 0.0002
Echinococcus granulosus cathepsin l cysteine peptidase 0.1096 0.4212 0.5054
Schistosoma mansoni tyrosine kinase 0.0009 0.0002 0.0001
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.002 0.0044 0.0052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0135 0.0133
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0044 0.0135 0.0161
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0044 0.0135 0.0161
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.01 0.0352 0.0422
Schistosoma mansoni acetylcholine receptor-related 0.002 0.0044 0.0042
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0057 0.0055
Schistosoma mansoni tyrosine kinase 0.0009 0.0002 0.0001
Echinococcus granulosus cysteine protease 0.0607 0.2319 0.2782
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Echinococcus granulosus glycine receptor subunit beta 0.0044 0.0135 0.0161
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0135 0.0133
Entamoeba histolytica cysteine protease, putative 0.0259 0.097 0.23
Giardia lamblia Cathepsin L-like protease 0.0259 0.097 0.0969
Entamoeba histolytica cysteine proteinase, putative 0.1096 0.4212 1
Echinococcus multilocularis lamin 0.0027 0.0071 0.0085
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Trypanosoma cruzi cysteine protease, putative 0.0607 0.2319 0.2747
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0009 0.0002 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0041 0.005
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0044 0.0135 0.0162
Echinococcus multilocularis glycine receptor subunit beta 0.0044 0.0135 0.0161
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0205 0.0203
Giardia lamblia Cathepsin B precursor 0.046 0.1749 0.1748
Giardia lamblia Cathepsin B precursor 0.0259 0.097 0.0969
Echinococcus multilocularis SH2 motif 0.0009 0.0002 0.0002
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.2319 0.5504
Echinococcus granulosus tensin 0.0009 0.0002 0.0002
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0041 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0259 0.097 0.1421
Echinococcus multilocularis SH2 domain containing protein 7 0.0009 0.0002 0.0002
Entamoeba histolytica SH2 domain containing protein 0.0009 0.0002 0.0001
Onchocerca volvulus 0.0044 0.0135 0.0317
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0005 0.0006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0135 0.0162
Echinococcus granulosus N chimaerin 0.0009 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.0009 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0041 0.0368
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1096 0.4212 0.6384
Brugia malayi STAT protein, DNA binding domain containing protein 0.0492 0.1873 0.2248
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0009 0.0002 0.0001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0059 0.1394
Plasmodium falciparum cysteine proteinase falcipain 3 0.1096 0.4212 0.4191
Schistosoma mansoni cathepsin s 0.0348 0.1315 0.1313
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0005 0.0009
Echinococcus multilocularis cathepsin b 0.2159 0.8333 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0005 0.0004
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Echinococcus multilocularis tyrosine kinase 0.0009 0.0002 0.0002
Echinococcus multilocularis glycine receptor subunit beta 0.0044 0.0135 0.0161
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0044 0.0135 0.0161
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0005 0.0004
Mycobacterium ulcerans hypothetical protein 0.0024 0.0059 0.1394
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0041 0.0052
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1096 0.4212 0.4191
Trypanosoma brucei cysteine peptidase C (CPC) 0.0847 0.3247 0.7089
Onchocerca volvulus 0.0009 0.0002 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0204 0.0202
Schistosoma mansoni hypothetical protein 0.0009 0.0002 0.0001
Entamoeba histolytica cysteine proteinase 1, putative 0.0607 0.2319 0.5504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Echinococcus granulosus SH2 domain containing adapter protein F 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Onchocerca volvulus 0.1096 0.4212 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0049
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0083
Echinococcus granulosus tyrosine protein kinase Src42A 0.0009 0.0002 0.0002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0059 0.1583
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.097 0.1164
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0005 0.0006
Schistosoma mansoni cpg binding protein 0.0031 0.0085 0.0083
Onchocerca volvulus Cathepsin L homolog 0.1096 0.4212 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0259 0.097 0.1163
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0005 0.0004
Echinococcus granulosus signal transduction protein lnk realted 0.0009 0.0002 0.0002
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.2589 1 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0131 0.0157
Onchocerca volvulus Cathepsin L homolog 0.1096 0.4212 1
Plasmodium falciparum serine repeat antigen 5 0.0259 0.097 0.0938
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0005 0.0009
Echinococcus multilocularis cathepsin L 0.0259 0.097 0.1163
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni tensin-related 0.0009 0.0002 0.0001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0017 0.0019
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0041 0.0095
Entamoeba histolytica cysteine protease, putative 0.0259 0.097 0.23
Schistosoma mansoni nAChR subunit 0.002 0.0044 0.0042
Echinococcus multilocularis N chimaerin 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0009 0.0002 0.0001
Echinococcus granulosus dna polymerase kappa 0.002 0.0041 0.0049
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0847 0.3247 0.7073
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0009 0.0002 0.0002
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.1143 0.4396 0.4376
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Echinococcus granulosus lamin dm0 0.0027 0.0071 0.0085
Entamoeba histolytica cysteine protease, putative 0.0259 0.097 0.23
Onchocerca volvulus 0.0009 0.0002 0.0001
Loa Loa (eye worm) ACC-1 protein 0.0044 0.0135 0.0161
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0044 0.0135 0.0133
Schistosoma mansoni tyrosine kinase 0.0009 0.0002 0.0001
Brugia malayi Cell death specification protein 2 0.0009 0.0001 0.0002
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0044 0.0135 0.0161
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0607 0.2319 0.2747
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0259 0.097 0.1163
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0259 0.097 0.0938
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0005 0.0006
Giardia lamblia Dipeptidyl-peptidase I precursor 0.1143 0.4396 0.4395
Echinococcus granulosus expressed conserved protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) bZIP transcription factor family protein 0.0009 0.0001 0.0001
Onchocerca volvulus 0.002 0.0044 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0131 0.0138
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0748 0.2863 0.6796
Giardia lamblia Encystation-specific protease 0.1143 0.4396 0.4395
Brugia malayi cathepsin Z-like cysteine proteinase 0.046 0.1749 0.2099
Schistosoma mansoni tensin 0.0009 0.0002 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.2319 0.5504
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0202
Loa Loa (eye worm) TK protein kinase 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0044 0.0135 0.0317
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0841 0.3224 0.3839
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0044 0.0052
Schistosoma mansoni cathepsin F (C01 family) 0.0748 0.2863 0.2862
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0057 0.0068
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0044 0.0135 0.0161
Loa Loa (eye worm) TK/ABL protein kinase 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Brugia malayi Hepatic leukemia factor 0.0009 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0847 0.3247 0.3866
Loa Loa (eye worm) hypothetical protein 0.0348 0.1315 0.1577
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0068
Schistosoma mansoni cpg binding protein 0.0031 0.0085 0.0083
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0009 0.0002 0.0001
Brugia malayi hypothetical protein 0.0009 0.0001 0.0002
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0204 0.0025
Entamoeba histolytica cysteine proteinase 2 0.0607 0.2319 0.5504
Brugia malayi Cathepsin L-like precursor 0.1096 0.4212 0.5054
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Onchocerca volvulus 0.0009 0.0002 0.0001
Plasmodium vivax serine-repeat antigen (SERA) 0.0259 0.097 0.0938
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0044 0.0052
Echinococcus multilocularis expressed conserved protein 0.0094 0.0328 0.0394
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0078 0.0093
Echinococcus multilocularis tyrosine protein kinase Abl 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0059 0.5
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0352 0.0832
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0204 0.0202
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0135 0.0162
Brugia malayi Cathepsin L-like precursor 0.1096 0.4212 0.5054
Onchocerca volvulus 0.0044 0.0135 0.0317
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0044 0.0052
Entamoeba histolytica hypothetical protein 0.0024 0.0057 0.0131
Loa Loa (eye worm) hypothetical protein 0.0259 0.097 0.1163
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0009 0.0002 0.0002
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0044 0.0135 0.0161
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0044 0.0135 0.0162
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0005 0.0006
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0035 0.5
Loa Loa (eye worm) cysteine protease 0.1096 0.4212 0.5054
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Echinococcus granulosus neuropeptide s receptor 0.0471 0.1789 0.2147
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0009 0.0002 0.0001
Onchocerca volvulus 0.0029 0.0078 0.0183
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0059 0.1394
Brugia malayi Tensin 0.0009 0.0002 0.0002
Echinococcus granulosus nAChR subunit 0.0044 0.0135 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0005 0.0006
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.2589 1 1
Onchocerca volvulus 0.001 0.0005 0.0009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0607 0.2319 0.2318
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0044 0.0135 0.0161
Trypanosoma cruzi cysteine peptidase, putative 0.0348 0.1315 0.1536
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0352 0.0422
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Schistosoma mansoni GTPase activating protein 0.0009 0.0002 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.1096 0.4212 0.503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0009 0.0002 0.0002
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0044 0.0135 0.0161
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.046 0.1749 0.2615
Schistosoma mansoni thyroid hormone receptor 0.001 0.0005 0.0004
Loa Loa (eye worm) SH2 domain-containing protein 0.0009 0.0002 0.0002
Echinococcus multilocularis SH2 motif 0.0009 0.0002 0.0002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0204 0.0359
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0005 0.0006
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0009 0.0002 0.0002
Schistosoma mansoni coup transcription factor 0.001 0.0005 0.0004
Schistosoma mansoni growth factor receptor-bound protein 0.0009 0.0002 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0059 0.007
Schistosoma mansoni tyrosine kinase 0.0009 0.0002 0.0001
Loa Loa (eye worm) STAT protein 0.0492 0.1873 0.2247
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2159 0.8333 0.8333
Brugia malayi Cathepsin L-like precursor 0.0748 0.2863 0.3435
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0348 0.1315 0.1577
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.046 0.1749 0.2099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.097 0.1421
Brugia malayi Tyrosine-protein kinase abl-1 0.0009 0.0002 0.0002
Echinococcus multilocularis signal transduction protein lnk realted 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0019
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0009 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0052
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0024 0.0057 0.0055
Entamoeba histolytica cysteine proteinase, putative 0.0748 0.2863 0.6796
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0518 0.0621
Echinococcus multilocularis cpg binding protein 0.0031 0.0085 0.0101
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0259 0.097 0.0969
Plasmodium vivax unspecified product 0.0607 0.2319 0.2292
Brugia malayi Cathepsin L-like precursor 0.1096 0.4212 0.5054
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0009 0.0002 0.0002
Brugia malayi bZIP transcription factor family protein 0.0009 0.0001 0.0002
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0009 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor A26 0.0471 0.1789 0.2147
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1705 0.6574 1
Schistosoma mansoni tensin 0.0009 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0124
Onchocerca volvulus Cathepsin F homolog 0.1096 0.4212 1
Brugia malayi CXXC zinc finger family protein 0.0029 0.0078 0.0094
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.2673 0.2672
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0017
Brugia malayi fibroinase precursor 0.0259 0.097 0.1164
Echinococcus multilocularis cathepsin L cysteine protease 0.1096 0.4212 0.5054
Trypanosoma cruzi cysteine proteinase, putative 0.0607 0.2319 0.2747
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0044 0.0052
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Echinococcus granulosus cathepsin L 0.0607 0.2319 0.2782
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0052
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0001 0.0001
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0009 0.0002 0.0002
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0009 0.0002 0.0002
Echinococcus granulosus SH2 domain containing protein 7 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0204 0.0244
Brugia malayi Protein kinase domain containing protein 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0009 0.0002 0.0001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0135 0.0162
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0059 0.0038
Giardia lamblia Cathepsin L precursor 0.0259 0.097 0.0969
Schistosoma mansoni DNA polymerase eta 0.002 0.0041 0.004
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0044 0.0135 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1096 0.4212 0.6384
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0259 0.097 0.0938
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0259 0.097 0.0969
Echinococcus granulosus cathepsin L 0.0259 0.097 0.1163
Brugia malayi cathepsin L-like cysteine proteinase 0.0259 0.097 0.1164
Plasmodium vivax unspecified product 0.0259 0.097 0.0938
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0259 0.097 0.1421
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.097 0.1164
Schistosoma mansoni nAChR subunit 0.0044 0.0135 0.0133
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0135 0.0162
Entamoeba histolytica cysteine protease, putative 0.0607 0.2319 0.5504
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Brugia malayi tRNA modification GTPase TrmE family protein 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0057 0.0068
Giardia lamblia Dipeptidyl-peptidase I precursor 0.1143 0.4396 0.4395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Onchocerca volvulus Putative nachr subunit 0.0044 0.0135 0.0317
Echinococcus granulosus growth factor receptor bound protein 2 0.0009 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1189 0.4574 1
Brugia malayi CHE-14 protein 0.0043 0.0131 0.0158
Trypanosoma cruzi cysteine proteinase, putative 0.0607 0.2319 0.2747
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0041 0.004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0005 0.0006
Schistosoma mansoni vav2 0.0009 0.0002 0.0001
Echinococcus granulosus c src tyrosine kinase 0.0009 0.0002 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0005 0.0006
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.2589 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0161
Giardia lamblia Cathepsin L precursor 0.0259 0.097 0.0969
Schistosoma mansoni nck2/grb4 0.0009 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.097 0.1421
Plasmodium vivax vivapain-2 0.1096 0.4212 0.4191
Echinococcus granulosus SH2 motif 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0259 0.097 0.1163
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0005 0.0006
Plasmodium falciparum serine repeat antigen 2 0.0259 0.097 0.0938
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0009 0.0002 0.0002
Brugia malayi SH2 domain containing protein 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1096 0.4212 0.6384
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0009 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.0009 0.0002 0.0002
Schistosoma mansoni cathepsin S (C01 family) 0.0259 0.097 0.0969

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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