Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.032 | 0.3438 | 0.3438 |
Chlamydia trachomatis | SWIB complex protein | 0.0899 | 1 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0899 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Schistosoma mansoni | TRABID protein (C64 family) | 0.032 | 0.3438 | 0.3438 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0899 | 1 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.0328 | 0.0328 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.032 | 0.3438 | 0.3438 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Toxoplasma gondii | ran binding protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | ring and YY1 binding protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.032 | 0.3438 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0899 | 1 | 1 |
Schistosoma mansoni | brg-1 associated factor | 0.0899 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0899 | 1 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.032 | 0.3438 | 1 |
Schistosoma mansoni | RNA binding protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0041 | 0.0285 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.0328 | 0.0328 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.032 | 0.3438 | 0.3438 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.0328 | 0.0328 |
Plasmodium vivax | hypothetical protein, conserved | 0.0899 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.032 | 0.3438 | 0.3438 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.032 | 0.3438 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0899 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0041 | 0.0285 | 1 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.032 | 0.3438 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0899 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.032 | 0.3438 | 0.3438 |
Schistosoma mansoni | fusion | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.032 | 0.3438 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0899 | 1 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0154 | 0.1557 | 0.1557 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.0328 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.0899 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0041 | 0.0285 | 0.0285 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.032 | 0.3438 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0899 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0899 | 1 | 1 |
Brugia malayi | YY1-associated factor 2 | 0.032 | 0.3438 | 0.3438 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.0328 | 0.0328 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.032 | 0.3438 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0154 | 0.1557 | 0.1557 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.032 | 0.3438 | 0.3438 |
Schistosoma mansoni | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.032 | 0.3438 | 0.3438 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.0328 | 0.0328 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0899 | 1 | 1 |
Onchocerca volvulus | 0.0899 | 1 | 1 | |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.032 | 0.3438 | 1 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.032 | 0.3438 | 0.3438 |
Loa Loa (eye worm) | acetyltransferase | 0.0154 | 0.1557 | 0.1557 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Echinococcus multilocularis | ring and YY1 binding protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0149 | 0.1508 | 0.1508 |
Trypanosoma brucei | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0154 | 0.1557 | 0.1557 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.032 | 0.3438 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0899 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.