Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.3313 | 0.3253 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0254 | 0.3313 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0713 | 1 | 1 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0254 | 0.3313 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.3313 | 0.3253 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0254 | 0.3313 | 0.3253 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0254 | 0.3313 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 1 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0713 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0254 | 0.3313 | 0.3253 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0713 | 1 | 1 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0713 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.3313 | 0.3253 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0254 | 0.3313 | 1 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0254 | 0.3313 | 0.3253 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0343 | 0.4615 | 0.4567 |
Echinococcus granulosus | snurportin 1 | 0.0343 | 0.4615 | 0.4567 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0713 | 1 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0713 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0254 | 0.3313 | 0.3253 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.3313 | 0.3253 |
Onchocerca volvulus | 0.0713 | 1 | 1 | |
Brugia malayi | RNA, U transporter 1 | 0.0091 | 0.0951 | 0.087 |
Plasmodium vivax | hypothetical protein, conserved | 0.0713 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0254 | 0.3313 | 0.3253 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0254 | 0.3313 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0713 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0713 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.3313 | 0.3253 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 1 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0254 | 0.3313 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0254 | 0.3313 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Chlamydia trachomatis | SWIB complex protein | 0.0713 | 1 | 0.5 |
Echinococcus multilocularis | snurportin 1 | 0.0343 | 0.4615 | 0.4567 |
Schistosoma mansoni | RNA binding protein | 0.0254 | 0.3313 | 0.3253 |
Schistosoma mansoni | zinc finger protein | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 1 | 1 |
Loa Loa (eye worm) | brahma associated protein | 0.0713 | 1 | 1 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0254 | 0.3313 | 1 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0254 | 0.3313 | 0.3253 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0713 | 1 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0713 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 1 | 1 |
Schistosoma mansoni | fusion | 0.0254 | 0.3313 | 0.3253 |
Toxoplasma gondii | ran binding protein | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0254 | 0.3313 | 0.3253 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0254 | 0.3313 | 0.3253 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Brugia malayi | YY1-associated factor 2 | 0.0254 | 0.3313 | 0.3253 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.3313 | 0.3253 |
Schistosoma mansoni | brg-1 associated factor | 0.0713 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.3313 | 0.3253 |
Schistosoma mansoni | hypothetical protein | 0.0343 | 0.4615 | 0.4567 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.3313 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0713 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0713 | 1 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0254 | 0.3313 | 1 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0254 | 0.3313 | 0.3253 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0254 | 0.3313 | 0.3253 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0713 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.