Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0044 | 0.0044 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0708 | 1 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.0692 | 0.8395 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0044 | 0.0127 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.034 | 0.034 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.2281 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0395 | 0.1676 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0171 | 0.0689 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.1897 |
Echinococcus granulosus | dnaJ subfamily B | 0.0419 | 0.5885 | 0.5885 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0126 | 0.0126 |
Echinococcus granulosus | cytochrome B | 0.0063 | 0.0792 | 0.0792 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0171 | 0.0171 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0631 | 0.8901 | 0.8901 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0126 | 0.0494 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0625 | 0.2695 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0044 | 0.0127 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0126 | 0.0126 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0044 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0126 | 0.0126 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0425 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0126 | 0.0126 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0044 | 0.0127 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.9883 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0044 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0126 | 0.0126 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0785 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0126 | 0.0126 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0425 | 1 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0167 | 0.2277 | 0.2277 |
Schistosoma mansoni | cytochrome b | 0.0063 | 0.0792 | 0.0792 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0044 | 0.0127 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0015 | 0.0015 |
Onchocerca volvulus | 0.0029 | 0.0316 | 0.2213 | |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.1897 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0167 | 0.2277 | 0.2277 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2281 | 0.2281 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0126 | 0.0494 |
Schistosoma mansoni | cytochrome b | 0.0063 | 0.0792 | 0.0792 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0171 | 0.2354 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0425 | 0.181 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0788 | 0.0788 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0015 | 0.0015 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0425 | 0.409 |
Echinococcus granulosus | alkaline phosphatase | 0.0167 | 0.2277 | 0.2277 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0044 | 0.0044 |
Toxoplasma gondii | apocytochrome b, putative | 0.0063 | 0.0792 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0044 | 0.0127 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0625 | 0.2695 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0425 | 1 |
Mycobacterium leprae | PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) | 0.0246 | 0.3406 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0126 | 0.0494 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0044 | 0.0127 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0425 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.0167 | 0.2277 | 0.2277 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0246 | 0.3406 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0171 | 0.2354 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0044 | 0.0044 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0126 | 0.0126 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0246 | 0.3406 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0171 | 0.2354 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0015 | 0.0015 |
Onchocerca volvulus | 0.0097 | 0.1275 | 1 | |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0015 | 0.0015 |
Echinococcus multilocularis | alkaline phosphatase | 0.0167 | 0.2277 | 0.2277 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.0167 | 0.2277 | 0.2277 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0044 | 0.0127 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0014 | 0.0093 | 0.0399 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0044 | 0.0044 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0425 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.0785 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0316 | 0.133 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0126 | 0.0126 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0171 | 0.0171 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0425 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.034 | 0.034 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0044 | 0.0044 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0044 | 0.0127 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0246 | 0.3406 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0171 | 0.2354 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0126 | 0.0126 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0171 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0425 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0044 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0126 | 0.0126 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0044 | 0.0127 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0044 | 0.0044 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0044 | 0.0044 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0044 | 0.0044 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0419 | 0.5885 | 0.5885 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.0785 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.1644 | 0.7187 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0425 | 0.0425 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.2281 | 0.2281 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0044 | 0.0044 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.1949 | 0.1949 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0425 | 0.0425 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0044 | 0.0044 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0171 | 0.113 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0044 | 0.0044 |
Echinococcus granulosus | smad | 0.0008 | 0.0015 | 0.0015 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0425 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0316 | 0.133 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0044 | 0.0127 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0024 | 0.0041 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0044 | 0.0127 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.1897 |
Wolbachia endosymbiont of Brugia malayi | cytochrome b subunit of the bc complex | 0.0063 | 0.0792 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0015 | 0.0015 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0167 | 0.2277 | 0.2277 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0171 | 0.2354 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0425 | 1 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0167 | 0.2277 | 0.2277 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0625 | 0.2695 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0425 | 0.181 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.1133 | 0.1133 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0015 | 0.0015 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0425 | 1 |
Plasmodium vivax | cytochrome b | 0.0063 | 0.0792 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0171 | 0.0171 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0171 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0785 | 0.0785 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.034 | 0.034 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.1949 | 0.1949 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0425 | 0.4801 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0093 | 0.0344 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0044 | 0.0127 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0246 | 0.3406 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0044 | 0.0127 |
Toxoplasma gondii | cytochrome b | 0.0063 | 0.0792 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0026 | 0.0049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0044 | 0.0127 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0044 | 0.0127 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0425 | 0.0425 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0014 | 0.0093 | 0.0344 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0425 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0419 | 0.5885 | 0.5885 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0044 | 0.0127 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0708 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0044 | 0.0127 |
Plasmodium falciparum | cytochrome b | 0.0063 | 0.0792 | 1 |
Schistosoma mansoni | smad | 0.0008 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0044 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0395 | 0.0395 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.1644 | 0.7187 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0316 | 0.0316 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2281 | 0.2281 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0044 | 0.0127 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0015 | 0.0015 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0171 | 0.0689 |
Brugia malayi | cytochrome b | 0.0063 | 0.0792 | 0.3429 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0044 | 0.0044 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.034 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0044 | 0.0044 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0425 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0395 | 0.1676 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0167 | 0.2277 | 0.2277 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0026 | 0.0026 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.2281 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0625 | 0.2695 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0015 | 0.0015 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0044 | 0.0127 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0044 | 0.0127 |
Echinococcus multilocularis | smad | 0.0008 | 0.0015 | 0.0015 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.1644 | 0.7187 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0785 | 0.1897 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0044 | 0.0044 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0631 | 0.8901 | 0.8901 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0044 | 0.0044 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0246 | 0.3406 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.0167 | 0.2277 | 0.2277 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0785 | 0.0785 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0171 | 0.0171 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0044 | 0.0044 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0044 | 0.0127 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0171 | 0.2354 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | cytochrome b | 0.0063 | 0.0792 | 0.3429 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0126 | 0.0494 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | > 1000 nM | Concentration of the Compound that inhibits electrically-induced contractions of the mouse vas deferens by 50% | ChEMBL. | 1323677 |
Ki (binding) | = 11 nM | Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay | ChEMBL. | 1323677 |
Ki (binding) | = 21 nM | Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay | ChEMBL. | 1323677 |
Ki (binding) | = 79 nM | Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay | ChEMBL. | 1323677 |
Ki (binding) | = 176 nM | Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay | ChEMBL. | 1323677 |
Ratio (binding) | = 0.5 | Ratio of the compound on opioid receptor mu (ki(nM)) to the opioid receptor delta (Ki(nM)) | ChEMBL. | 1323677 |
Ratio (binding) | = 2.3 | Ratio of the compound on opioid receptor mu (ki(nM)) to the opioid receptor delta (Ki(nM)) | ChEMBL. | 1323677 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.