Detailed information for compound 1651774

Basic information

Technical information
  • TDR Targets ID: 1651774
  • Name: 4-[4-[2-[4-(4-aminophenoxy)phenyl]-2-adamanty l]phenoxy]aniline
  • MW: 502.646 | Formula: C34H34N2O2
  • H donors: 2 H acceptors: 0 LogP: 8.4 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: Nc1ccc(cc1)Oc1ccc(cc1)C1(C2CC3CC1CC(C2)C3)c1ccc(cc1)Oc1ccc(cc1)N
  • InChi: 1S/C34H34N2O2/c35-28-5-13-32(14-6-28)37-30-9-1-24(2-10-30)34(26-18-22-17-23(20-26)21-27(34)19-22)25-3-11-31(12-4-25)38-33-15-7-29(36)8-16-33/h1-16,22-23,26-27H,17-21,35-36H2
  • InChiKey: OYVBSGFRWFEXHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [4-[4-[2-[4-(4-aminophenoxy)phenyl]-2-adamantyl]phenoxy]phenyl]amine
  • 2,2-bis[4-(4-aminophenoxy)phenyl]adamantane
  • NSC711118
  • NCI60_039083

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major trypanothione reductase 0.0096 0.2165 0.8018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0953 0.0939
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0117 0.2688 1
Mycobacterium tuberculosis Probable reductase 0.0218 0.5147 0.896
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0645 0.2248
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0009 0.0052 0.0037
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0278 0.3884
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.2688 1
Brugia malayi ecdysteroid receptor 0.001 0.0089 0.0068
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.2165 0.2153
Brugia malayi nuclear hormone receptor 0.001 0.0089 0.0068
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0645 0.2248
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0009 0.0052 0.0037
Echinococcus multilocularis 0.0018 0.0278 0.0263
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0117 0.2688 0.338
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0645 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0223 0.0207
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.2688 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0645 0.2248
Echinococcus granulosus ring and YY1 binding protein 0.0117 0.2688 0.2676
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0278 0.0409
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0278 0.3884
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0009 0.0052 0.0037
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0278 0.0289
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0009 0.0052 0.0124
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0278 0.0856
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0009 0.0052 0.0124
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0953 0.0939
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Echinococcus multilocularis muscleblind protein 1 0.0149 0.3479 0.3469
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0329 0.7849 0.7845
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0278 0.3884
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0009 0.0052 0.0013
Entamoeba histolytica thioredoxin reductase, putative 0.0009 0.0052 0.5
Schistosoma mansoni Smad4 0.0008 0.0037 0.0021
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0009 0.0052 0.0037
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0117 0.2688 1
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0009 0.0052 0.0067
Brugia malayi CXXC zinc finger family protein 0.0029 0.0552 0.066
Loa Loa (eye worm) hypothetical protein 0.0117 0.2688 0.3394
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0052 0.0067
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0117 0.2688 0.3394
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0278 0.0409
Onchocerca volvulus 0.0117 0.2688 0.338
Echinococcus multilocularis SWI:SNF matrix associated 0.0329 0.7849 0.7845
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0089 0.0068
Echinococcus multilocularis glutamate synthase 0.0009 0.0052 0.0037
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0278 0.3884
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0278 0.3884
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0089 0.0068
Trichomonas vaginalis ferritin, putative 0.0008 0.0045 0.0057
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0117 0.2688 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0089 0.0074
Echinococcus granulosus FTZ F1 alpha 0.001 0.0089 0.0074
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0223 0.0238
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0242 0.5739 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.2688 0.3394
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0223 0.0207
Mycobacterium tuberculosis Probable dehydrogenase 0.0218 0.5147 0.896
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0645 0.076
Onchocerca volvulus Huntingtin homolog 0.0125 0.2882 0.3629
Trichomonas vaginalis glutamate synthase, putative 0.0009 0.0052 0.0067
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0496 0.1682
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0431 0.0504
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0037 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0089 0.0074
Treponema pallidum NADH oxidase 0.0033 0.0645 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0645 1
Mycobacterium ulcerans monoxygenase 0.0009 0.0052 0.0124
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0278 0.0856
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0089 0.0068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0089 0.0068
Schistosoma mansoni hypothetical protein 0.0329 0.7849 0.7845
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0089 0.0074
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0117 0.2688 0.3394
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0645 0.0821
Brugia malayi cytochrome P450 0.0018 0.0278 0.0309
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0009 0.0052 0.0013
Schistosoma mansoni zinc finger protein 0.0117 0.2688 0.2676
Schistosoma mansoni ferritin 0.0008 0.0045 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0278 0.0409
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0009 0.0052 0.5
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0218 0.5147 0.896
Echinococcus multilocularis ferritin 0.0008 0.0045 0.0029
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0645 0.063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Echinococcus multilocularis dnaJ subfamily B 0.0417 1 1
Echinococcus granulosus GPCR family 2 0.0016 0.0223 0.0207
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0089 0.0074
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0278 0.3884
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Schistosoma mansoni smad1 5 8 and 0.0008 0.0037 0.0021
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0009 0.0052 0.0124
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0009 0.0052 0.0037
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0037 0.0021
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0056 0.0025
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0052 0.0067
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0009 0.0052 0.0037
Loa Loa (eye worm) hypothetical protein 0.0149 0.3479 0.4406
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0009 0.0052 0.5
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0278 0.3884
Schistosoma mansoni hypothetical protein 0.0009 0.0052 0.0037
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0645 0.0821
Echinococcus granulosus zinc finger protein Ran binding 0.0117 0.2688 0.2676
Echinococcus multilocularis zinc finger protein Ran binding 0.0117 0.2688 0.2676
Trypanosoma brucei hypothetical protein, conserved 0.0117 0.2688 1
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0009 0.0052 0.0067
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0329 0.7849 1
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0329 0.7849 1
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0496 0.1682
Toxoplasma gondii ran binding protein 0.0117 0.2688 0.338
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0009 0.0052 0.0013
Echinococcus multilocularis Smad4 0.0008 0.0037 0.0021
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0009 0.0052 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0953 0.0939
Leishmania major hypothetical protein, conserved 0.0117 0.2688 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0645 0.076
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0009 0.0052 0.0124
Plasmodium falciparum thioredoxin reductase 0.0033 0.0645 0.076
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0496 0.1682
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0059 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0278 0.0409
Leishmania major cytochrome p450-like protein 0.0018 0.0278 0.0856
Mycobacterium tuberculosis Probable oxidoreductase 0.0242 0.5739 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0009 0.0052 0.002
Schistosoma mansoni hypothetical protein 0.0329 0.7849 0.7845
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.2748 0.3471
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0645 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0645 0.076
Echinococcus multilocularis SWI:SNF matrix associated 0.0329 0.7849 0.7845
Brugia malayi nuclear receptor NHR-88 0.001 0.0089 0.0068
Onchocerca volvulus Huntingtin homolog 0.0125 0.2882 0.3629
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0278 0.0409
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0645 0.2248
Trypanosoma cruzi WLM domain containing protein, putative 0.0117 0.2688 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0089 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.2688 1
Schistosoma mansoni hypothetical protein 0.0417 1 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0052 0.0067
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0089 0.0074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0645 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.2688 0.3394
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0645 0.1053
Chlamydia trachomatis SWIB complex protein 0.0329 0.7849 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0052 0.002
Schistosoma mansoni hypothetical protein 0.0016 0.0223 0.0207
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0278 0.3884
Brugia malayi Cytochrome P450 family protein 0.0018 0.0278 0.0309
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.2748 0.3471
Loa Loa (eye worm) hypothetical protein 0.0149 0.3479 0.4406
Brugia malayi brahma associated protein 60 kDa 0.0329 0.7849 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0117 0.2688 1
Leishmania major cytochrome p450-like protein 0.0027 0.0496 0.1682
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0089 0.0074
Onchocerca volvulus 0.0117 0.2688 0.338
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0223 0.0207
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0089 0.0074
Brugia malayi Cytochrome P450 family protein 0.0057 0.1226 0.1523
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0278 0.3884
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0645 0.2248
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.2165 0.2725
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0089 0.0074
Treponema pallidum oxidoreductase 0.0009 0.0052 0.0124
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0645 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0645 1
Schistosoma mansoni hypothetical protein 0.0034 0.0669 0.0654
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0953 0.0939
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.119 0.1459
Schistosoma mansoni hypothetical protein 0.0018 0.0278 0.0263
Schistosoma mansoni RNA binding protein 0.0117 0.2688 0.2676
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.2165 0.3724
Echinococcus multilocularis GPCR, family 2 0.0016 0.0223 0.0207
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0009 0.0052 0.0013
Brugia malayi Cytochrome P450 family protein 0.0027 0.0496 0.0588
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0278 0.0409
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0117 0.2688 0.2676
Mycobacterium ulcerans glutamate synthase subunit beta 0.0009 0.0052 0.0124
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0009 0.0052 0.0037
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0089 0.0074
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0552 0.066
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0218 0.5147 0.896
Schistosoma mansoni hypothetical protein 0.0016 0.0223 0.0207
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0278 0.3884
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0009 0.0052 0.0037
Leishmania major cytochrome p450-like protein 0.0018 0.0278 0.0856
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0278 0.3884
Schistosoma mansoni TRABID protein (C64 family) 0.0117 0.2688 0.2676
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0052 0.0067
Echinococcus granulosus ferritin 0.0008 0.0045 0.0029
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0009 0.0052 0.0037
Schistosoma mansoni hypothetical protein 0.0016 0.0223 0.0207
Leishmania major hypothetical protein, conserved 0.0117 0.2688 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0037 0.0021
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0278 0.0409
Schistosoma mansoni thyroid hormone receptor 0.001 0.0089 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0089 0.0068
Brugia malayi Muscleblind-like protein 0.0149 0.3479 0.4406
Loa Loa (eye worm) glutathione reductase 0.0096 0.2165 0.2725
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0645 0.076
Trichomonas vaginalis apoptosis inducing factor, putative 0.0009 0.0052 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0089 0.0068
Echinococcus multilocularis muscleblind protein 0.0149 0.3479 0.3469
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0009 0.0052 0.0124
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0009 0.0052 0.0013
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0278 0.3884
Echinococcus multilocularis cpg binding protein 0.0031 0.0593 0.0578
Schistosoma mansoni cpg binding protein 0.0031 0.0593 0.0578
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0089 0.0068
Onchocerca volvulus 0.0329 0.7849 1
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0117 0.2688 0.338
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0278 0.0409
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0223 0.0238
Schistosoma mansoni disulfide oxidoreductase 0.0009 0.0052 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Schistosoma mansoni cpg binding protein 0.0029 0.0552 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0278 0.0409
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0223 0.0238
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0218 0.5147 0.896
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0089 0.0074
Schistosoma mansoni smad1 5 8 and 0.0008 0.0037 0.0021
Echinococcus multilocularis SWI:SNF matrix associated 0.0329 0.7849 0.7845
Schistosoma mansoni thyroid hormone receptor 0.001 0.0089 0.0074
Mycobacterium ulcerans hypothetical protein 0.0009 0.0052 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Mycobacterium ulcerans dehydrogenase 0.0009 0.0052 0.0124
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0009 0.0052 0.0124
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0278 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0278 0.0409
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0329 0.7849 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0278 0.3884
Schistosoma mansoni glutamate synthase 0.0009 0.0052 0.0037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0089 0.0074
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0953 0.0939
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0009 0.0052 0.0037
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0089 0.0074
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0089 0.0048
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0278 0.3884
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0953 0.1173
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0009 0.0052 0.5
Brugia malayi Thioredoxin reductase 0.0096 0.2165 0.2725
Schistosoma mansoni ferritin light chain 0.0008 0.0045 0.0029
Schistosoma mansoni glutamate synthase 0.0009 0.0052 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0089 0.0068
Trypanosoma brucei hypothetical protein, conserved 0.0117 0.2688 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0645 0.2248
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0645 0.076
Echinococcus granulosus Smad4 0.0008 0.0037 0.0021
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0009 0.0052 0.5
Schistosoma mansoni nuclear hormone receptor 0.001 0.0089 0.0074
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0278 0.0409
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0223 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0089 0.0068
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0089 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Loa Loa (eye worm) brahma associated protein 0.0329 0.7849 1
Trichomonas vaginalis glutamate synthase, putative 0.0009 0.0052 0.0067
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0089 0.0074
Trypanosoma cruzi WLM domain containing protein, putative 0.0117 0.2688 1
Schistosoma mansoni ferritin 0.0008 0.0045 0.0029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0242 0.5739 1
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0117 0.2688 0.338
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0278 0.0409
Brugia malayi brahma associated protein 60 kDa 0.0329 0.7849 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0089 0.0068
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0496 0.7513
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Schistosoma mansoni sulfide quinone reductase 0.0009 0.0052 0.0037
Leishmania major hypothetical protein, conserved 0.0117 0.2688 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0009 0.0052 0.002
Mycobacterium ulcerans ferredoxin reductase 0.0009 0.0052 0.0124
Echinococcus granulosus expressed protein 0.0008 0.0045 0.0029
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0278 0.3884
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0089 0.0068
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0089 0.0074
Brugia malayi MH2 domain containing protein 0.0119 0.2748 0.3471
Schistosoma mansoni apoferritin-2 0.0008 0.0045 0.0029
Echinococcus granulosus glutamate synthase 0.0009 0.0052 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0089 0.0068
Brugia malayi Cytochrome P450 family protein 0.0027 0.0496 0.0588
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0052 0.0067
Loa Loa (eye worm) hypothetical protein 0.001 0.0089 0.0068
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0117 0.2688 0.3394
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0089 0.0074
Plasmodium falciparum thioredoxin reductase 0.0096 0.2165 0.271
Brugia malayi hypothetical protein 0.0125 0.2882 0.3642
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0117 0.2688 1
Loa Loa (eye worm) hypothetical protein 0.005 0.1053 0.1301
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0278 0.3884
Echinococcus multilocularis ring and YY1 binding protein 0.0117 0.2688 0.2676
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0218 0.5147 0.896
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0089 0.0074
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0009 0.0052 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0089 0.0068
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0009 0.0052 0.0013
Schistosoma mansoni sulfide quinone reductase 0.0009 0.0052 0.0037
Schistosoma mansoni brg-1 associated factor 0.0329 0.7849 0.7845
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.1053 0.1301
Schistosoma mansoni glutamate synthase 0.0009 0.0052 0.0037
Schistosoma mansoni ferritin light chain 0.0008 0.0045 0.0029
Echinococcus granulosus smad 0.0008 0.0037 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0089 0.0074
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0009 0.0052 0.0124
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0496 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0089 0.0068
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0089 0.0068
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0278 0.3884
Mycobacterium leprae putative cytochrome p450 0.0018 0.0278 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0278 0.0409
Brugia malayi steroid hormone receptor 0.001 0.0089 0.0068
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0089 0.0068
Echinococcus multilocularis smad 0.0008 0.0037 0.0021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0218 0.5147 0.896
Onchocerca volvulus 0.0117 0.2688 0.338
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0009 0.0052 0.5
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0089 0.0048
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0242 0.5739 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.2688 0.3394
Echinococcus multilocularis expressed protein 0.0008 0.0045 0.0029
Loa Loa (eye worm) cytochrome P450 0.0018 0.0278 0.0309
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0278 0.0409
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0645 0.076
Onchocerca volvulus 0.001 0.0089 0.0048
Schistosoma mansoni smad1 5 8 and 0.0008 0.0037 0.0021
Onchocerca volvulus 0.0117 0.2688 0.338
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0089 0.0048
Echinococcus granulosus cpg binding protein 0.0031 0.0593 0.0578
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0009 0.0052 0.0124
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0496 0.0588
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0278 0.3884
Loa Loa (eye worm) hypothetical protein 0.0034 0.0669 0.0809
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0009 0.0052 0.0013
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0009 0.0052 0.0013
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0278 0.0263
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0089 0.0074
Schistosoma mansoni hypothetical protein 0.0016 0.0223 0.0207
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0089 0.0068
Plasmodium falciparum glutathione reductase 0.0033 0.0645 0.076
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0089 0.0068
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0329 0.7849 1
Echinococcus granulosus muscleblind protein 0.0149 0.3479 0.3469
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0009 0.0052 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.1226 0.1523
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0645 0.063
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.2165 0.271
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0496 0.0588
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0645 0.2248
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0052 0.0067
Onchocerca volvulus 0.0029 0.0552 0.0641
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0278 0.3884
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0009 0.0052 0.002
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0645 0.2248
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0089 0.0068
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0278 0.0856
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.2165 0.8018
Brugia malayi SWIB/MDM2 domain containing protein 0.0329 0.7849 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0037 0.0021
Schistosoma mansoni smad 0.0008 0.0037 0.0021
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0278 0.0409
Schistosoma mansoni apoferritin-2 0.0008 0.0045 0.0029
Leishmania major hypothetical protein, conserved 0.0117 0.2688 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0089 0.0074
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0117 0.2688 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0953 0.1173
Trypanosoma brucei trypanothione reductase 0.0096 0.2165 0.8018
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0278 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0278 0.0409
Schistosoma mansoni fusion 0.0117 0.2688 0.2676
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.1053 0.1301
Brugia malayi glutamate synthase 0.0009 0.0052 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0953 0.0939
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0278 0.0856
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0089 0.0074
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0645 0.063
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0089 0.0068
Schistosoma mansoni ferritin 0.0008 0.0045 0.0029
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0278 0.0409
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0089 0.0068
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0278 0.0856
Loa Loa (eye worm) hypothetical protein 0.0009 0.0056 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0089 0.0068
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0059 0.0029
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0089 0.0074
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0089 0.0074
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0117 0.2688 1
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0009 0.0052 0.0013
Schistosoma mansoni cytochrome P450 0.0018 0.0278 0.0263
Leishmania major hypothetical protein, conserved 0.0117 0.2688 1
Loa Loa (eye worm) programmed cell death 8 0.0009 0.0052 0.002
Plasmodium vivax hypothetical protein, conserved 0.0329 0.7849 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0431 0.0504
Loa Loa (eye worm) hypothetical protein 0.0125 0.2882 0.3642
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0117 0.2688 0.2676
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0329 0.7849 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0645 0.076
Trichomonas vaginalis conserved hypothetical protein 0.0329 0.7849 1
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0329 0.7849 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0089 0.0074
Toxoplasma gondii thioredoxin reductase 0.0096 0.2165 0.271
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0037 0.0021
Loa Loa (eye worm) hypothetical protein 0.0117 0.2688 0.3394
Echinococcus granulosus Zinc finger RanBP2 type 0.0117 0.2688 0.2676
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.2165 0.2153
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0009 0.0052 0.0124
Schistosoma mansoni hypothetical protein 0.0329 0.7849 0.7845
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0329 0.7849 0.7845
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0645 0.0778
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0009 0.0052 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.1352 0.1338
Schistosoma mansoni ferritin 0.0008 0.0045 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0278 0.0409
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0645 0.2248
Mycobacterium ulcerans NADH dehydrogenase 0.0009 0.0052 0.0124
Schistosoma mansoni hypothetical protein 0.0117 0.2688 0.2676
Brugia malayi glutathione reductase 0.0096 0.2165 0.2725
Entamoeba histolytica disulphide oxidoreductase, putative 0.0009 0.0052 0.5
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0009 0.0052 0.0067
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.1053 0.1301
Brugia malayi YY1-associated factor 2 0.0117 0.2688 0.3394
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0089 0.0074
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0278 0.3884
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0089 0.0068
Chlamydia trachomatis DNA topoisomerase I 0.0329 0.7849 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0223 0.0238
Loa Loa (eye worm) hypothetical protein 0.0125 0.2882 0.3642
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0089 0.0074
Schistosoma mansoni cpg binding protein 0.0031 0.0593 0.0578
Echinococcus granulosus SWI:SNF matrix associated 0.0329 0.7849 0.7845
Schistosoma mansoni coup transcription factor 0.001 0.0089 0.0074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0953 0.0939
Plasmodium vivax glutathione reductase, putative 0.0096 0.2165 0.271
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0059 0.0044
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0117 0.2688 0.2676
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0117 0.2688 0.3394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0645 0.2248
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0669 0.0809
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0009 0.0052 0.0037
Treponema pallidum thioredoxin reductase (trxB) 0.0009 0.0052 0.0124
Plasmodium falciparum glutathione reductase 0.0096 0.2165 0.271
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0009 0.0052 0.0124
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0278 0.0409

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5.521 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.41 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.301 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.202 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.199 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.178 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.108 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.962 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.94 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.86 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.842 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.626 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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