Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0281 | 0.0966 | 0.0966 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0281 | 0.0966 | 0.0966 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0281 | 0.0966 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1399 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Giardia lamblia | Cathepsin B precursor | 0.0506 | 0.2784 | 0.5 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Echinococcus multilocularis | cathepsin b | 0.1399 | 1 | 1 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0281 | 0.0966 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1399 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0506 | 0.2784 | 1 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1399 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0281 | 0.0966 | 0.0966 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0281 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | ctsf protein | 0.0281 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0281 | 0.0966 | 0.0966 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0506 | 0.2784 | 0.2784 |
Onchocerca volvulus | Cathepsin L homolog | 0.0281 | 0.0966 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0506 | 0.2784 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0281 | 0.0966 | 0.0966 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0281 | 0.0966 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.0966 | 0.0966 |
Entamoeba histolytica | cysteine protease, putative | 0.0281 | 0.0966 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1399 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1399 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0281 | 0.0966 | 0.0966 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.0966 | 0.0966 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0281 | 0.0966 | 0.0966 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0506 | 0.2784 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0506 | 0.2784 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0281 | 0.0966 | 0.0966 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0281 | 0.0966 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0506 | 0.2784 | 0.2012 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0506 | 0.2784 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0281 | 0.0966 | 0.0966 |
Plasmodium vivax | vivapain-2 | 0.0281 | 0.0966 | 0.5 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0281 | 0.0966 | 0.0966 |
Onchocerca volvulus | Cathepsin L homolog | 0.0281 | 0.0966 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.1399 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0281 | 0.0966 | 0.5 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0281 | 0.0966 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.0281 | 0.0966 | 0.0966 |
Toxoplasma gondii | cathepsin B | 0.0506 | 0.2784 | 1 |
Onchocerca volvulus | 0.0281 | 0.0966 | 0.5 | |
Echinococcus multilocularis | cysteine protease | 0.0281 | 0.0966 | 0.0966 |
Echinococcus granulosus | cathepsin l1 | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | fibroinase | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0281 | 0.0966 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | cathepsin B | 0.0506 | 0.2784 | 0.2784 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1399 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0281 | 0.0966 | 0.0966 |
Brugia malayi | Cathepsin L-like precursor | 0.0281 | 0.0966 | 0.0966 |
Echinococcus multilocularis | cathepsin b | 0.1399 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.0966 | 0.0966 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0281 | 0.0966 | 0.0966 |
Echinococcus granulosus | cathepsin b | 0.1399 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0281 | 0.0966 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.