Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Cyclin fold protein | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin family protein | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0051 | 0.289 | 0.289 |
Echinococcus granulosus | cyclin B | 0.0135 | 1 | 1 |
Mycobacterium tuberculosis | Transcriptional regulatory protein | 0.0051 | 0.289 | 0.5 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Plasmodium falciparum | transcriptional regulatory protein sir2a | 0.0051 | 0.289 | 0.289 |
Echinococcus granulosus | cyclin B3 1 | 0.0135 | 1 | 1 |
Giardia lamblia | Transcriptional regulator, Sir2 family | 0.0051 | 0.289 | 0.289 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2883 | 0.2883 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0051 | 0.289 | 0.289 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2883 | 0.2883 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Plasmodium vivax | NAD-dependent deacetylase, putative | 0.0051 | 0.289 | 1 |
Toxoplasma gondii | cyclin domain protein, cyclin H family protein | 0.0033 | 0.1387 | 0.191 |
Echinococcus multilocularis | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | cyclin, putative | 0.0135 | 1 | 1 |
Trypanosoma brucei | Silent information regulator 2 related protein 3 | 0.0051 | 0.289 | 0.289 |
Echinococcus multilocularis | cyclin | 0.0033 | 0.1387 | 0.1387 |
Plasmodium vivax | cyclin 4, putative | 0.0033 | 0.1387 | 0.4797 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0135 | 1 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclin b3 | 0.0135 | 1 | 1 |
Echinococcus granulosus | Cyclin L1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin t1 | 0.0033 | 0.1387 | 0.1387 |
Leishmania major | NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe | 0.0051 | 0.289 | 0.289 |
Leishmania major | cyclin | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0135 | 1 | 1 |
Giardia lamblia | Cyclin fold protein 1, putative | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | cyclin 6, putative | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin B3 | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2883 | 0.2883 |
Trichomonas vaginalis | cyclins, putative | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin D, putative | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0051 | 0.289 | 0.289 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclins | 0.0135 | 1 | 1 |
Entamoeba histolytica | cyclin, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin G | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Hypothetical protein | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B3, putative | 0.0033 | 0.1387 | 0.1387 |
Toxoplasma gondii | cyclin, N-terminal domain-containing protein | 0.0033 | 0.1387 | 0.191 |
Echinococcus granulosus | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | cyclin 3 | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin B | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin b3 | 0.0135 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0103 | 0.726 | 1 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0051 | 0.289 | 0.289 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1542 | 0.1542 |
Echinococcus granulosus | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin, putative | 0.0135 | 1 | 1 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | cyclin 9 | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclin | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0135 | 1 | 1 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0135 | 1 | 1 |
Trypanosoma brucei | mitotic cyclin | 0.0033 | 0.1387 | 0.1387 |
Mycobacterium leprae | Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) | 0.0034 | 0.1537 | 0.5 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1542 | 0.1542 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | Cyclin L1 | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin A3 4 | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin B3, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B, putative | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Leishmania major | cyclin 9, putative | 0.0033 | 0.1387 | 0.1387 |
Plasmodium falciparum | cyclin | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1542 | 0.1542 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2883 | 0.2883 |
Leishmania major | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Giardia lamblia | Cyclin A | 0.0135 | 1 | 1 |
Plasmodium vivax | cyclin homologue, putative | 0.0033 | 0.1387 | 0.4797 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | cyclin, putative | 0.0135 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma cruzi | cyclin 9, putative | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin B3 1 | 0.0135 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.1387 | 0.4797 |
Plasmodium falciparum | cyclin dependent kinase binding protein, putative | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin C, putative | 0.0033 | 0.1387 | 0.1387 |
Trypanosoma brucei | cyclin dependent kinase-binding protein, putative | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0051 | 0.289 | 0.289 |
Trichomonas vaginalis | cyclins, putative | 0.0033 | 0.1387 | 0.1387 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin A3 4 | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin A, putative | 0.0135 | 1 | 1 |
Leishmania major | mitotic cyclin, putative | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin k | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin A, putative | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclin B | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0135 | 1 | 1 |
Onchocerca volvulus | 0.0135 | 1 | 1 | |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | cyclins | 0.0135 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Mycobacterium ulcerans | NAD-dependent deacetylase | 0.0051 | 0.289 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclins, putative | 0.0135 | 1 | 1 |
Toxoplasma gondii | cyclin dependent kinase binding protein | 0.0033 | 0.1387 | 0.191 |
Toxoplasma gondii | hypothetical protein | 0.0033 | 0.1387 | 0.191 |
Echinococcus granulosus | cyclin k | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | CYL-1 protein | 0.0033 | 0.1387 | 0.1387 |
Plasmodium falciparum | cyclin 1 | 0.0033 | 0.1387 | 0.1387 |
Schistosoma mansoni | cyclin l | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0135 | 1 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0135 | 1 | 1 |
Schistosoma mansoni | cyclin d | 0.0033 | 0.1387 | 0.1387 |
Toxoplasma gondii | cyclin 4, putative | 0.0033 | 0.1387 | 0.191 |
Toxoplasma gondii | histone deacetylase SIR2 | 0.0051 | 0.289 | 0.3981 |
Giardia lamblia | Cyclin B-like protein | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin D, putative | 0.0135 | 1 | 1 |
Plasmodium vivax | cyclin dependent kinase binding protein, putative | 0.0033 | 0.1387 | 0.4797 |
Schistosoma mansoni | cyclin k | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0051 | 0.289 | 0.289 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin C | 0.0033 | 0.1387 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cyclin y | 0.0033 | 0.1387 | 0.1387 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0135 | 1 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | cyclin C | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B, putative | 0.0033 | 0.1387 | 0.1387 |
Trichomonas vaginalis | cyclin B3, putative | 0.0135 | 1 | 1 |
Echinococcus granulosus | cyclin G2 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0051 | 0.289 | 0.289 |
Echinococcus granulosus | cyclin t1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0033 | 0.1387 | 0.1387 |
Echinococcus multilocularis | cyclins | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0033 | 0.1387 | 0.1387 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.